LOCUS       NM_178740               8518 bp    mRNA    linear   ROD 01-AUG-2024
DEFINITION  Mus musculus SLIT and NTRK-like family, member 4 (Slitrk4),
            transcript variant 1, mRNA.
ACCESSION   NM_178740
VERSION     NM_178740.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8518)
  AUTHORS   Matsumoto,Y., Miwa,H., Katayama,K.I., Watanabe,A., Yamada,K.,
            Ito,T., Nakagawa,S. and Aruga,J.
  TITLE     Slitrk4 is required for the development of inhibitory neurons in
            the fear memory circuit of the lateral amygdala
  JOURNAL   Front Mol Neurosci 17, 1386924 (2024)
   PUBMED   38736483
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8518)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 8518)
  AUTHORS   Zhou,Y.Q., Bao,T.S., Xie,J.X., Yao,L.L., Yu,S.T., Li,Q.,
            Huang,P.Q., Zhou,W.Z., Wang,Y.Y., Chen,S.Y., Wang,X.Q., Zhang,X.L.,
            Jiang,S.H., Yi,S.Q., Zhang,Z.G., Ma,M.Z., Hu,L.P., Xu,J. and Li,J.
  TITLE     The SLITRK4-CNPY3 axis promotes liver metastasis of gastric cancer
            by enhancing the endocytosis and recycling of TrkB in tumour cells
  JOURNAL   Cell Oncol (Dordr) 46 (4), 1049-1067 (2023)
   PUBMED   37012514
  REMARK    GeneRIF: The SLITRK4-CNPY3 axis promotes liver metastasis of
            gastric cancer by enhancing the endocytosis and recycling of TrkB
            in tumour cells.
REFERENCE   4  (bases 1 to 8518)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 8518)
  AUTHORS   Yamagata,A., Sato,Y., Goto-Ito,S., Uemura,T., Maeda,A.,
            Shiroshima,T., Yoshida,T. and Fukai,S.
  TITLE     Structure of Slitrk2-PTPdelta complex reveals mechanisms for
            splicing-dependent trans-synaptic adhesion
  JOURNAL   Sci Rep 5, 9686 (2015)
   PUBMED   25989451
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 8518)
  AUTHORS   Beaubien,F. and Cloutier,J.F.
  TITLE     Differential expression of Slitrk family members in the mouse
            nervous system
  JOURNAL   Dev Dyn 238 (12), 3285-3296 (2009)
   PUBMED   19924824
REFERENCE   7  (bases 1 to 8518)
  AUTHORS   Cheng,T.W. and Gong,Q.
  TITLE     Secreted TARSH regulates olfactory mitral cell dendritic complexity
  JOURNAL   Eur J Neurosci 29 (6), 1083-1095 (2009)
   PUBMED   19302145
REFERENCE   8  (bases 1 to 8518)
  AUTHORS   Aruga,J., Yokota,N. and Mikoshiba,K.
  TITLE     Human SLITRK family genes: genomic organization and expression
            profiling in normal brain and brain tumor tissue
  JOURNAL   Gene 315, 87-94 (2003)
   PUBMED   14557068
REFERENCE   9  (bases 1 to 8518)
  AUTHORS   Aruga,J. and Mikoshiba,K.
  TITLE     Identification and characterization of Slitrk, a novel neuronal
            transmembrane protein family controlling neurite outgrowth
  JOURNAL   Mol Cell Neurosci 24 (1), 117-129 (2003)
   PUBMED   14550773
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK053065.1, AK032263.1, AL669956.10 and BC079655.1.
            
            On Jul 27, 2018 this sequence version replaced NM_178740.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK053065.1, AK046301.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2990              AK053065.1         2-2991
            2991-3523           AK032263.1         2882-3414
            3524-4107           AL669956.10        20851-21434         c
            4108-8518           BC079655.1         1-4411
FEATURES             Location/Qualifiers
     source          1..8518
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 34.57 cM"
     gene            1..8518
                     /gene="Slitrk4"
                     /gene_synonym="6430513G13; D930039I09Rik"
                     /note="SLIT and NTRK-like family, member 4"
                     /db_xref="GeneID:245446"
                     /db_xref="MGI:MGI:2442509"
     exon            1..197
                     /gene="Slitrk4"
                     /gene_synonym="6430513G13; D930039I09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            198..269
                     /gene="Slitrk4"
                     /gene_synonym="6430513G13; D930039I09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            270..8494
                     /gene="Slitrk4"
                     /gene_synonym="6430513G13; D930039I09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3584..3589
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slitrk4"
                     /gene_synonym="6430513G13; D930039I09Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3605
                     /gene="Slitrk4"
                     /gene_synonym="6430513G13; D930039I09Rik"
                     /note="major polyA site"
ORIGIN      
        1 ctgggtgcgc gcgcggtgtc tggccgggtg cgcgcgcgcg ccgctgcccg cttgcttgcc
       61 tgctaaaggc tgttctgtgg gcttgaccag cgagcgggag ccaagaagct ggatcccaga
      121 tcaagtagag agcatcgcgg aaactgagga gcgagtcgga aagcagtggg ccctccacag
      181 gacttggggc tccagagata aagctgctca aagaccgtgg catggggact cctcttcgtc
      241 ggcagtgaca gcctgtggtc tgagtgaaga ttatttgtct ttattcagaa gcatagagtt
      301 gtttgctgat tgcaagaaga tgtttctttg gctctttctg attgtgtcag ccctgatttc
      361 ttctacaaat gcagattctg acatatcagt ggaaatttgc aatgtgtgtt cctgcgtgtc
      421 agtagagaat gtgctctatg tcaactgtga gaaggtttca gtctacaggc caaaccagct
      481 gaaaccacct tggtctaatt tctatcatct caatttccaa aacaattttt taaatatcct
      541 ctatccaaat acattcgtga atttttctca tgcagtatct ctgcatctgg gaaataataa
      601 gctgcagaac attgagggag gagcctttct cgggctcagt gcattaaagc agttgcactt
      661 gaacaacaat gaattaaaga ttctccgagc tgacactttc cttggcatag agaacttgga
      721 gtatctccag gctgactaca atttaatcaa gtatattgaa cgaggagcct tcaataagct
      781 ccataaactg aaagttctca ttcttaatga caatctgatt tcattccttc ctgataatat
      841 ttttcgattt gcatctttaa cccatttgga tatacgagga aacagaatcc agaaacttcc
      901 ttatattgga gttctagaac acattggccg ggttgttgag ttgcagctgg aagataatcc
      961 ttggaactgt agctgtgatt tgttgcctct aaaggcttgg ctggagaata tgccatataa
     1021 catttacata ggagaagcta tttgtgaaac tcccagtgac ttatatggaa ggcttttaaa
     1081 ggaaaccaac aagcaagaac tatgccccat gggtacaggc agtgactttg acgtacgcat
     1141 tctgcctcca tctcagcagg agaatggctt tactactccc aatggtcaca ctactcagac
     1201 aaccttgcac agattagtga caaaaccacc caaaacaaca aatccttcca aaatctctgg
     1261 aattgtggca ggcaaagccc tatccaacag aaatctcagt cagattgtgt catatcaaac
     1321 aagagtgcct cctcttacac cttgtccagt accttgcttt tgcaaaacac atccttctga
     1381 tttgggattg agtgtgaatt gccaagagaa aaatatacag tccatgtctg aattgacacc
     1441 aaaacctttg aatgccaaga agttgcatgt caatggtaat aacatcaaag atgtggacat
     1501 ttcagacttc actgagtttg aggggctgga tttgctccat ttaggcagca atcagattac
     1561 gttgatcaaa ggagaagtat tccacaatct tactaatctg cgcaggcttt atctcaatgg
     1621 caatcagatt gaaaggctat accctgaaat attttcagga cttcataacc tgcagtatct
     1681 ttatttggag tacaacttga ttaaggaaat tttagcaggc acctttgact ccatgccaaa
     1741 tttgcagcta ctgtacttga acaataatct cttaaaaagc ctgccagttt acatcttttc
     1801 tggagcacca cttgctagac tgaacctgag aaacaacaaa ttcatgtacc tacctgtcag
     1861 cggagtactt gatcagttgc agtctcttac acaaattgac ttagagggca acccttggga
     1921 ctgcacctgc gacttggtag cattaaagtt gtggctggag aagttaaatg atgggattgt
     1981 tgtgaaagaa ctgaaatgtg agactcctgt tcagtttgcc aacatcgaat tgaagtccct
     2041 caaaaatgaa atcttatgcc ctaaactctt aaacaagcca tcagcaacat tcacaagccc
     2101 tgcgcctgca attaccttca ccactccatt gggtcctatt cgaagtcctc ctgggggccc
     2161 agtgccatta tctattttaa tcttaagtat tctggtggtt ctcattttaa ctgtctttgt
     2221 tgcattttgc cttcttgttt ttgtgctgag acgtaacaag aaacccacag tgaagcatga
     2281 aggtctgggg aattctgagt gtggctccat gcagctgcaa ctaaggaaac atgaccacaa
     2341 aaccaataaa aaagatggac tgagcacaga agcattcatt ccacaaacca tcgaacagat
     2401 gagcaaaagt cacacctgtg gcctgaaaga gtcagaaact gggttcatgt tttctgatcc
     2461 tccgggacag aaggtaatga tgagaaatgc tgctgacaag gacaaagatt tattgcatgt
     2521 ggataccagg aaaagactga gcacaattga cgagctggac gaactcttcc ctagcagaga
     2581 ttccaatgtg ttcattcaaa attttcttga aagcaaaaag gagtataaca gcattggtgt
     2641 cagtggcttt gagattcgct atcctgaaaa acaacaagat aaaaaaaaca agaagtcact
     2701 gataggtggt aaccacagta aaattgttgt tgaacaaagg aagagtgagt attttgaact
     2761 gaaggcaaaa cttcagagtt cccccgacta cctacaggtc cttgaagagc aaacagcttt
     2821 gaacaagata taggtcatgt aatctgactt catacagagg acaatattta atgatgaaag
     2881 tgccttttgt tgacttctaa cttccaaata ctatattacc attaggcata gaggcaggtg
     2941 tttccaaggg tatctcatta actgtagctg taaagatatg tcaagtagaa gagaattccc
     3001 ttaatagatt ttactacata aaacctatac tgtggaatcc tatggggata ctgcaaactc
     3061 tattgccaaa gggatgcttt ataaacataa tacactgaat ttaacctcaa gaggcaaatc
     3121 agttttgtat cctgatgcaa aaccttcgtc tctttgtgct ttgtaaagca aactcgagaa
     3181 aactggtacc agtgtctgta cctcagctgg gtccttcatc ttgcacgtag attaagttgg
     3241 tgaaactgga ataacccttt tgatttgtgg cattgtaaca actctgtgta aagattatct
     3301 gaaaagtgta aaaaaaaaac acaaataagc atgcaaagag agaacatttg atagtatttg
     3361 taaatcagta aaatttatgg cctgcatctt gaaattgctg gatttataat gttaaattgt
     3421 gcaaatactt gtttaaaata taccatgcat tacataatta taaaataaat ttgaacactt
     3481 taagtattac ctgtctatac ataaaaacct aaaggagaaa aaaaatcaat gtgagttaca
     3541 tagcatttgt ggtgatctag aaaaaaacat gatgtttatc agaattaaac atggctcaaa
     3601 ttaaactaga gtttgttctc agttatgtca aatacccaca atccttaaag gttgtccaaa
     3661 attagcaagt gcttaccgtg tgagcgcacc caaagctatt tttgtaacat aattcatatt
     3721 tatgaagtac tttgtatact aaataggaaa acacgtactc cttaatatgt atttaatatg
     3781 cttgacttac tctcctgatc acagcaaatt aatcagtaag cataaattta gataagaaaa
     3841 agaaatatga aaatgaaact gaagctaatg tgtacagaaa tattttggac tctgtgatca
     3901 ggtataattt aaaagcagaa aaaaatacaa aaaatataaa aaagtaaaaa aaaaaaacag
     3961 ttctgtgcaa ttcttgtgaa tttagcatat tatcttcaga tttgttacca actgtgcatt
     4021 ttaaaatagg ctcattagtt ttatagtatt gtgtctgggg cagttgttat ttgccatcaa
     4081 ttgtcttgct tttcaggatt ctatgagctt aattcaaata gttttaattg caatatttaa
     4141 caaattaatg actaaggtta atagtatctt gtatgcatca gtatcctgtt ctttcatcat
     4201 tctgactatc agataatcta gtagaactat aaacatcatg gtaatcttgg ctaccaaagc
     4261 caccctgcta aatgcttgca ctggtctcag atgaattcat gatctacaac tacaactgat
     4321 atgcccctgt gtttgcgtgt gatgttaagt tctagatcaa aattggtcaa atgatcgagg
     4381 catttgataa tgggctgata tctgaagatg tttaggagct atgactagca aattaatatt
     4441 cagaacatca ttgtcttctt ggccacttct ctcttctctc ttctcttctc tctctctctc
     4501 tctctctctc tttctctctc tctctctctc tctctctctc tctctctctc tctctctctc
     4561 tctctcattc tctctgtctc tctctctgtg agtgtgtttt gtgtgtgtgt gttgtgatgt
     4621 gatgaattac tgttttattc agtaaggtag tcaagaaggc atacagacat tctttatgaa
     4681 tttcaagtgg cagatgtttt gacgcagctt ccaaaaggat attatagtta aagttgtagc
     4741 agcactccct ttattaaata ctaatttcaa gattttatgt gtttgttcca atttttttaa
     4801 agaaaaactg gacattatta caggagtgtg tatatgtgtg tgtgtttgtg tgtgtgtgtg
     4861 tgtgtgtgtg tgtgtataca tgcatgtgtg tttaagtgta tattcacaag tatagataac
     4921 ttggagattt tttttagata gcaaataaaa atctccctat gtatgtgctg gtgctcttaa
     4981 aactttaatg tgtaattttc agtttcatga caatgtctgt gaaaacttta tatgaatata
     5041 aatacatcca aacaaataat tgctttctga tcttgaaaga aaaaaatata ttcaaatgct
     5101 aattttcatc tgcagtttca taaggacatt taatatgcca ttaccatgca tgcatgcatc
     5161 catggattaa agggctccta atgcacactg acaggataaa gatgcaaagt cttctaacaa
     5221 cgtgttttta tttattcaat caataatgtt tggattcaga aatcttaaat gcacacttac
     5281 aggaggaacc agaaagctcc atgcataacc tggggctaat aggtcattgg gatgatgcat
     5341 ttttattcag tgtggtggtg tttgaaggat atttcaaggt ttccgaaaat tgtcaatcct
     5401 aagagtacct gccaccatct caaagcttgc tgtagtataa tggctatctc acactcttct
     5461 gctgaaaact attaatgttc aaaatatttt taagaaaaga aaatgtaatt taattgttcg
     5521 ttgtaatttg gaggtcctaa ttgtaaatgg aagtaacaaa tccttggtta aggctagtat
     5581 actttcctta actaaagtca ttgtgcctac attataccgt gtatgctaat ttgcacctgt
     5641 ctctcattag ttcttgtatc ttttatgata ctgtagttag gtataaattc tgagttgagt
     5701 acaagagcag ttaaaatact gtatctacat tttgttggct tcaactataa tcttgatgtt
     5761 agtttaaccc cttgagatat gatatgtaaa tggtaaaaca ttttttagtg actttgattc
     5821 aaatcttaaa agccaagaag ggatcatttc caatatggtg tgaaacatcg tggtcttctt
     5881 ggcttgatat tcttgtgtac agactgtttt agaacagttg cagagaaaac tagatcttat
     5941 gaaatcagtg aaggggtgag ataatatatt gtgtctgtgt aatataaatc aagttttaaa
     6001 ttattttttt atgaaatcaa taaaaatgat tcaattcctt aaaagtaaat ctttgtgtaa
     6061 ttttatgaga aagcagctat taaagtacag tgattcaaat atataaggca atttatatca
     6121 atacttaatt ttccatgcta aataagagta tcaagaaata tattaattag gaagttttaa
     6181 agacacttgt catttgttgc tttacataaa catttagttt tgtatgccat aaggatgcat
     6241 aaatactaaa gatcatggcc tcatgagtaa tgtcataggt attttagaaa tatcagagtc
     6301 aatctcagaa atgtatggcg ataatgttaa tctacacact tgcatgacta ttacatagaa
     6361 agtatatgaa atgagcacag tgagattgtt ttatttttct ttttaaattt ttcttgttat
     6421 tgttgcatcc aaagagttag ggagcaaata tactcagaat gtatttatag ttactatttt
     6481 gaaataaagt agagaatatg tattatatta cttttaccct gatttgatta tatctatttt
     6541 agataaattc actttaaaaa tcaagtaatg ctattaaaat ataatgtaaa tcacagcaaa
     6601 gaacaattct aatgaattat gtttttgttg aattacaaca agatattaga attcattgaa
     6661 tgacattttt ctggaagtat taataaaatt gtttggagca atgttatttc tgaagcagca
     6721 ttttgttaag tatatttatc ttttcttttt ttttcagaaa aaaataaaac agtaaccaaa
     6781 ctgattatat cactcaaatt tgagggtaag atatatagct ttataatact gtttacacac
     6841 aacttaagtg ttaagcctct gttaaaagat gtgttcttta caaacatact tgcaataggt
     6901 attccctagt tctagcaatc ccttaacgat cagatgtcag acagtgttaa aagttaatat
     6961 attttgatcc tattacattc tcactcacca tttggaatat aacataactt caaattagca
     7021 aatactggta ttcgatctag aaaatcaact caaatacttt tagagaaact tcaaaatttt
     7081 tacatcctat agcaagcttg actgatttta agttactgtg gtaaatggtt atttttaaca
     7141 tagtttcttt aaaagtaacc aaaaatatca atcacttgat gcatttactg ttgttgaaaa
     7201 aaaaaagtga accaactgca ttatagttaa ctagagagca gaaaaaaaaa tatcaaaagg
     7261 ctgaatttac cataaagttg ttttaaatca tgtatcctta agctacatga agcaaacaaa
     7321 gtgcacagaa atataaatta atatttctgt ggccttacta ctagacataa acagtgctga
     7381 aagtgggcac actatagata gcaagcacaa ggcatttttc tcagtcactc taatatgtaa
     7441 acaagtggca tcaaataaaa atacaggctt atgttcagtg ttcatgcaaa attacttact
     7501 agccagatga gctgaactag taccacatag taaatgttat caattactat gaataattat
     7561 aagttaattg atgattttta tctttcaatt gcagatttct aggagatctg tcttttgtta
     7621 aattcaaaac caaatgggag gttaagtaaa cctaaataac ttatttttta tttacaaaaa
     7681 ctgcctctag tgtgaatttt aatttaattt tattgtattg ttttctttat tctacttact
     7741 ttctaatgat ttatatgata gcattggaaa aggacaattt aaagaatgtg gttttactat
     7801 ctcctctgtg aaatactatg attttctaaa attttgtaaa atttactttt taatttgttc
     7861 ttcttatacc tacacagggg aaatacactg aagctctgag gcaattgaat actgccccat
     7921 ataatatgag agtgggagta caaaatattg aaactcaaca ttgtttgata actataagtt
     7981 agtttggcaa tagaatccag aaccaagaaa taactattca atctttcctt acagttgact
     8041 tttgtagaca ttccctgtat ataacataga ttttagccct tctgatatta caaaagaaag
     8101 gacaattttt tttctaaaaa attcacaaat ggagccttta gagagcaaat gaaagtatac
     8161 aataaaacaa tatcttttac ttttaaattg actatatata aaaaagggca gtcttttaga
     8221 atttttgaac aatatacttc ttccaggtgg caattcataa atagtagttc atgtcagatg
     8281 ctgttgataa acatctaagg aagccatgct gtgcaatgga tattaattat ggcaacattt
     8341 gagaatcata ttaagctctg ttctccctac taaaaattgc aatgtatatt tccatcattg
     8401 ttttatgtaa actgaatcat tgtactaaaa ttctggagtt gatatgaagt aactttaatg
     8461 ctgttttcat gaataaaagt cttttcttat aggtaaaaaa aaaaaaaaaa aaaaaaaa
//
