LOCUS       NM_172796               3856 bp    mRNA    linear   ROD 01-JUL-2024
DEFINITION  Mus musculus schlafen 9 (Slfn9), mRNA.
ACCESSION   NM_172796 XM_913966
VERSION     NM_172796.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3856)
  AUTHORS   Zhang,P., Hu,X., Li,Z., Liu,Q., Liu,L., Jin,Y., Liu,S., Zhao,X.,
            Wang,J., Hao,D., Chen,H. and Liu,D.
  TITLE     Schlafen 11 triggers innate immune responses through its
            ribonuclease activity upon detection of single-stranded DNA
  JOURNAL   Sci Immunol 9 (96), eadj5465 (2024)
   PUBMED   38875319
  REMARK    GeneRIF: Schlafen 11 triggers innate immune responses through its
            ribonuclease activity upon detection of single-stranded DNA.
REFERENCE   2  (bases 1 to 3856)
  AUTHORS   Alvi,E., Mochizuki,A.L., Katsuki,Y., Ogawa,M., Qi,F., Okamoto,Y.,
            Takata,M. and Mu,A.
  TITLE     Mouse Slfn8 and Slfn9 genes complement human cells lacking SLFN11
            during the replication stress response
  JOURNAL   Commun Biol 6 (1), 1038 (2023)
   PUBMED   37833372
  REMARK    GeneRIF: Mouse Slfn8 and Slfn9 genes complement human cells lacking
            SLFN11 during the replication stress response.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3856)
  AUTHORS   Bustos,O., Naik,S., Ayers,G., Casola,C., Perez-Lamigueiro,M.A.,
            Chippindale,P.T., Pritham,E.J. and de la Casa-Esperon,E.
  TITLE     Evolution of the Schlafen genes, a gene family associated with
            embryonic lethality, meiotic drive, immune processes and
            orthopoxvirus virulence
  JOURNAL   Gene 447 (1), 1-11 (2009)
   PUBMED   19619625
REFERENCE   4  (bases 1 to 3856)
  AUTHORS   Neumann,B., Zhao,L., Murphy,K. and Gonda,T.J.
  TITLE     Subcellular localization of the Schlafen protein family
  JOURNAL   Biochem Biophys Res Commun 370 (1), 62-66 (2008)
   PUBMED   18355440
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK036579.1 and AY261800.1.
            
            On Oct 13, 2006 this sequence version replaced NM_172796.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK036579.1, AY261800.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1303              AK036579.1         2-1304
            1304-2559           AY261800.1         1212-2467
            2560-3856           AK036579.1         2561-3857
FEATURES             Location/Qualifiers
     source          1..3856
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 50.3 cM"
     gene            1..3856
                     /gene="Slfn9"
                     /gene_synonym="9830137M10Rik"
                     /note="schlafen 9"
                     /db_xref="GeneID:237886"
                     /db_xref="MGI:MGI:2445121"
     exon            1..243
                     /gene="Slfn9"
                     /gene_synonym="9830137M10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            244..1313
                     /gene="Slfn9"
                     /gene_synonym="9830137M10Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             251..2983
                     /gene="Slfn9"
                     /gene_synonym="9830137M10Rik"
                     /codon_start=1
                     /product="schlafen family member 9"
                     /protein_id="NP_766384.2"
                     /db_xref="CCDS:CCDS25154.1"
                     /db_xref="GeneID:237886"
                     /db_xref="MGI:MGI:2445121"
                     /translation="METYLSLVVKRSYPDLIIYAGEVTLGEKVRNKKDSKKRKLEKTR
                     ITQAACALLNSGGGVIVIQMANQSEQPERMGQDLETSLRNLIPSLDLQAFFETKQQED
                     KFYIFVKSWSSSPEDDSTKPRICSLGTSLYCRSLTSKVAMDSRDAFYFLKKKKAYIKC
                     SPTDDRAPPAKIPRTMSQKSLESNPAFEIFQSKKLEYGQRLLFSESTSIEFKQFDTEN
                     AQKYMKDIIPEYISAFANTQGGYLFIGVDDKSIILGCPKDNVDPDSLKIVANEAISKL
                     PVFHFCSSKDKNKVSYETRVIDVFQEGNLYGYLCVIKVEPFCCAVFSEAPISWMVDKE
                     KGVYTLNTEEWVRMMVDVGPEAASNDLSRDFECQLSLSDSPPHCRPVYSKKGLEHKVD
                     LQQRLFQVSPDCLKYTPESLWSELCSQHERLEDLVKQQIRSFSCGLLILSRSWAVDLN
                     LEEKQEVICDALLIAQNSPPILYTILGEQDEQGQDYCTRTAFTLKQKLVNTGGYTGRV
                     CVMTKVLCLSSQNNNKTSGGSVSPIDYPSSYNLANIQEMQGLLQALVIVLLNFRSFLS
                     DQLGCEVLNLLTAQQYEILSKSLRKTRELFVHGLPGSGKTIIAMKIMEKIRNTFHCET
                     DRILYICENQPLRDFIQAKNICQAVTRKTFMNYKFKTERFQHIIIDEAQNFRTEDGNW
                     YEKAKGITRGMKNCPGILWIFLDYFQTSHLQESGLPDFSLQYPKEELTQVVRNADKIA
                     EFLQQELQKIRDNPPCSIPQESLNILHEFKWSQGVSGTYEITYLTLEKMVSYITDKCD
                     VFLSKGYSPQDIAVLFSTDREKKAYEHMFLREMRKRRRASHMNDESVCHSNMFDSIRR
                     FSGLERSIVFGINPIATEQPISHNLLLCLASRAMKHLYILYLSTPEGQSSMVAC"
     exon            1314..1448
                     /gene="Slfn9"
                     /gene_synonym="9830137M10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1449..2172
                     /gene="Slfn9"
                     /gene_synonym="9830137M10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2173..3856
                     /gene="Slfn9"
                     /gene_synonym="9830137M10Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccaattcgc tgtgaccact gctagccaaa cccatgctag acccggggct gctcctctga
       61 acctcacaga caggcgacca gtccacaaat gaaacaccac ctggccacag accagaagat
      121 tctgggccgg aggctgagtt cgggaaggaa agggagactt acattcctgc ctgtttctaa
      181 attctgcttt cccagccggc cagggaacag cgatcaaaag tcttttctca caaaatgaaa
      241 gtggatcagc atggagacat atctctcctt agtggtgaaa cggtcttacc cagatttgat
      301 catctatgca ggagaagtga ctctgggaga aaaagttcga aataaaaagg actcaaagaa
      361 aagaaagctg gagaagacaa gaattacaca ggctgcatgt gctctgttaa actctggagg
      421 aggagtgatt gttatacaaa tggccaacca gagtgagcaa cctgagagga tgggacagga
      481 cttggaaaca tctttgagaa accttattcc atcccttgat ttgcaggctt tctttgagac
      541 caagcaacag gaggataagt tttacatttt tgttaagtct tggagctcca gccctgaaga
      601 tgattccact aagcctcgaa tttgcagcct gggcacttcc ctgtactgtc gatctctcac
      661 ttctaaggtt gccatggatt caagagatgc attttacttt ctgaaaaaaa agaaggcata
      721 tatcaaatgc agtccgactg atgacagagc tccacctgct aaaattccca gaaccatgag
      781 tcagaaaagc cttgaatcaa atccagcttt tgaaattttc caaagtaaga aacttgaata
      841 tggccaacgc ttgctttttt ctgaatccac atctatagag tttaaacaat tcgataccga
      901 aaatgcccaa aaatatatga aagacataat tccagagtac atctccgcgt ttgcaaacac
      961 ccagggaggc tatcttttca ttggagtgga tgataagagt atcatcctgg gatgcccaaa
     1021 agacaacgtt gaccctgact ctttgaaaat tgtggcaaat gaagcaatat ccaagttgcc
     1081 agttttccat ttttgttcat ctaaagacaa gaacaaggtg tcttatgaga ccagagtcat
     1141 agatgtgttt caagagggaa atttgtatgg ttatctctgt gtgatcaaag tagagccatt
     1201 ctgctgtgca gtgttctcag aggctcccat ttcatggatg gtagacaagg agaaaggtgt
     1261 ctacacactg aacaccgagg aatgggtacg catgatggtg gatgttggcc cagaggcagc
     1321 ttccaatgat ctatctagag attttgaatg tcagctgagt ctatccgaca gccctccaca
     1381 ctgcagacca gtgtattcta aaaagggact ggaacataaa gtcgacctgc agcagcgttt
     1441 atttcaagtg tcaccagact gtttaaagta tactcctgaa tctctctgga gtgagctgtg
     1501 ttcccagcat gagagactag aggatttagt aaagcagcaa atacgttctt tctcctgtgg
     1561 tttgctgatc ctctctagaa gctgggctgt ggacctgaac ctggaagaga agcaggaagt
     1621 catctgtgat gctctgctga ttgcacagaa tagccccccc atcctctaca ccatccttgg
     1681 ggagcaggat gagcagggtc aggactactg cacccgcact gcctttactc tgaagcagaa
     1741 gctggtgaac actggtggct acactgggag agtgtgtgtc atgaccaagg ttctctgcct
     1801 gagctctcag aacaataaca agaccagtgg gggctcagtc tctcctattg attacccaag
     1861 ctcctataac cttgcaaaca tccaggaaat gcagggcttg ctgcaggccc ttgtgattgt
     1921 cttgctcaac ttcagatctt tcttgagtga ccagcttggc tgtgaagttt tgaatcttct
     1981 cacagcccaa cagtatgaga tactctcaaa aagtctccgc aaaaccagag aactatttgt
     2041 gcatggcttg ccgggctcag ggaagacaat catagccatg aaaatcatgg aaaagatcag
     2101 aaacacattc cactgtgaaa cagatagaat cctctacatc tgtgaaaatc agccattgag
     2161 ggacttcatc caggcaaaaa atatctgcca ggcagtgacc cggaaaacct tcatgaatta
     2221 taaatttaag acagagaggt tccaacacat cattattgat gaagcccaga atttccgcac
     2281 tgaggatgga aactggtatg agaaggcaaa aggaatcact cgaggaatga aaaactgtcc
     2341 tggaattctc tggatctttc tggactattt tcagaccagt cacttgcagg agagtggcct
     2401 cccagatttc tcactccagt atccaaagga agagctcaca caagtggtac gcaatgcaga
     2461 taaaatagct gagttcctac aacaagagtt gcaaaaaatc agagataacc ctccatgcag
     2521 cattcctcaa gagtccctaa atattctcca tgaatttaag tggtcccaag gtgtatcagg
     2581 cacctatgag attacatact tgactttgga aaagatggta agctatataa cagataagtg
     2641 tgatgttttc ttgagtaaag gctattctcc ccaagatatt gcagtgcttt tcagcacaga
     2701 tagggagaag aaagcctatg agcatatgtt cctgagagaa atgaggaaga ggaggagagc
     2761 atctcacatg aatgacgagt ctgtctgtca ttctaacatg tttgacagca tccgtcgatt
     2821 ctcaggactg gaaagaagca ttgtgtttgg tatcaatccc attgcaactg agcagcccat
     2881 ttcccacaac ctattgctct gcctggcttc cagagcaatg aaacatctgt atattctgta
     2941 tctttcaact cctgaggggc agagctcaat ggtggcatgc tgaatgggat atatgagacc
     3001 ctaagttcaa tccctgatga tgagaaagtt aaatcgagtt gaggtccttc gggacaagaa
     3061 gaaagataaa gatataacaa aaccttgttc tgtagttttg acaaatgtag gaaaaaatta
     3121 ccaatgtgta tatcgtaact aactgaggct gaaaacaaag ctggagagaa gactggcaag
     3181 gcaatgtaca catgacatag gctatgggaa cgttgagacc ataaggactg aaaccagaga
     3241 tgaagacaac tcaatacagt aagtcatatc caattcttaa aacagacttc cattttaaat
     3301 tggttaatac atttatgaaa atattgtata aggataaaga taaagactaa aaacataata
     3361 ttaagtagca ctggggtctg cgcctggagc tgattttgtg ccacagcgct ccaatcccta
     3421 aataccactg ggaaagaact ggcctcccac aagtgtggac aagcctgtga gcgcaggtaa
     3481 gtccaccact tctgctcaga ggtacacacc tggaactctc agaacacagg aaccaaatca
     3541 catgaggcaa cagcaagaac acaagcaaca gataccaagg ccacttggca tcatcagaac
     3601 ccagttctcc ctccacagcg agctatcatg ggtaccccac acaccagaaa agcaagactc
     3661 tgatttaaaa tcagatttca tgatgatgat agactttaag aaggacataa gtaactccct
     3721 taaagaaata caggagaaca caggtataca ggtagaagcc cttaaagagg aaacataaaa
     3781 ttcccttaaa gaattgcagg aaaacacaac caaacaggtg aaggaattga acaaaaccat
     3841 ccagaatcta aaaatg
//
