LOCUS       NM_134071               3742 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus SMC5-SMC6 complex localization factor 1 (Slf1), mRNA.
ACCESSION   NM_134071
VERSION     NM_134071.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3742)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3742)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3742)
  AUTHORS   Liu,T., Chen,H., Kim,H., Huen,M.S., Chen,J. and Huang,J.
  TITLE     RAD18-BRCTx interaction is required for efficient repair of
            UV-induced DNA damage
  JOURNAL   DNA Repair (Amst) 11 (2), 131-138 (2012)
   PUBMED   22036607
  REMARK    GeneRIF: RAD18 interacts with BRCTx in a phosphorylation-dependent
            manner
REFERENCE   4  (bases 1 to 3742)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 3742)
  AUTHORS   Adams,D.J., van der Weyden,L., Gergely,F.V., Arends,M.J., Ng,B.L.,
            Tannahill,D., Kanaar,R., Markus,A., Morris,B.J. and Bradley,A.
  TITLE     BRCTx is a novel, highly conserved RAD18-interacting protein
  JOURNAL   Mol Cell Biol 25 (2), 779-788 (2005)
   PUBMED   15632077
  REMARK    GeneRIF: Results describe the cloning, characterization, and
            targeted mutagenesis of Brctx, a novel gene with a BRCT motif
            [Brctx].
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122418.4 and AC161266.2.
            
            On Feb 8, 2008 this sequence version replaced NM_134071.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17253012.8332796.1,
                                           SRR1660821.113519.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-116               AC122418.4         83947-84062
            117-230             AC122418.4         92701-92814
            231-306             AC122418.4         92975-93050
            307-547             AC122418.4         93945-94185
            548-710             AC122418.4         106681-106843
            711-839             AC122418.4         113311-113439
            840-983             AC122418.4         114738-114881
            984-1127            AC122418.4         115791-115934
            1128-1262           AC122418.4         118359-118493
            1263-1316           AC122418.4         127004-127057
            1317-1475           AC122418.4         128072-128230
            1476-1639           AC122418.4         128947-129110
            1640-1768           AC122418.4         134955-135083
            1769-1934           AC122418.4         135809-135974
            1935-2082           AC122418.4         152668-152815
            2083-2228           AC161266.2         182174-182319       c
            2229-2392           AC161266.2         180903-181066       c
            2393-2523           AC161266.2         180112-180242       c
            2524-2616           AC161266.2         178135-178227       c
            2617-2799           AC161266.2         177547-177729       c
            2800-3742           AC161266.2         174113-175055       c
FEATURES             Location/Qualifiers
     source          1..3742
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 40.98 cM"
     gene            1..3742
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /note="SMC5-SMC6 complex localization factor 1"
                     /db_xref="GeneID:105377"
                     /db_xref="MGI:MGI:2145448"
     exon            1..116
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..3281
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /note="BRCT domain containing 1; ankyrin repeat
                     domain-containing protein 32; BRCT domain-containing
                     protein 1; ankyrin repeat domain 32; protein BRCTx"
                     /codon_start=1
                     /product="SMC5-SMC6 complex localization factor protein 1"
                     /protein_id="NP_598832.3"
                     /db_xref="CCDS:CCDS26657.2"
                     /db_xref="GeneID:105377"
                     /db_xref="MGI:MGI:2145448"
                     /translation="MEDSATKHIIQMTGFKMEEKEALVKLLLKLDCTFIKSEKYKNCT
                     HLIAERLCKSEKFLAACAAGKWVLTKDYIIHSAKSGRWLDETTYEWGYKIEKDSHYSP
                     QMQSAPKRWREELKRTGAPGAFHRWKVVLLVRADKRSDSLVRVLEAGKANVILPKNSP
                     SGITHVIASNARISAEREQENFKAPFYPIQYLGDFLLEKEIQNDEHSQISPAWTKYNN
                     QEKGNDVGFPEMKGAGENMYRTQNKMENHNKNVSDRFVLSEHHKKKFKDFRKDIRSVK
                     KRNTLRRHGLENQKETKKKDKNIQRSYILRKKNKKEGYCKTDDAHDTIRSMLKKRGHY
                     REQKEMKNPLLTDGTKESKTKDVKTNMNLIEIKNALKKQIYKDIYRAQAVRYNCIRVD
                     KQPVYNVEVKNSEFPRGILNLIENLIEGQFFKEAIEELSSLQAHYIPPVCLLHAILEN
                     VLQDKIDTFSGRYFHILSALLHLHPPWKSPAMLKYYLELFQCPTCMKGAWDFTEVLIR
                     SCLFNEDFCHQISENISTKVVNLTLLKFFFNLLEGEVRHLSQKLCDWSDSQSLKVTEK
                     AILHEIFWSGSETSGLLTKPVNMLLEWTIYSHKEKCKSNDVFKHELSYLLTGILGAAV
                     DYWIFLGIQMGRNVIRHMSDDLGSYISLSCDDFSSKELEIFICSFSSSWLQMFVAEAI
                     FKKLCLQGPTSTCTEPLSLQKIIDSYLPILGKMDIHGAGKMQSPKKLCQRPCLESQRA
                     LLMLNGAKRKQAEGRPELLELNRAKCSSSLKKLKKKSEELSCSKENCPSLVTKMNFHK
                     TNLKGETALHRVCIKNQVEKLIILLSLPGIDINVKDNAGWTPLHEACNYGNTECVQEI
                     LQRCPEVDLLTQVDGVTPLHDALSNGHVEIGKLLLQRGGPELLQQRNSKGELPLDYVL
                     SPKDKEELFAITNIDDTVDNFHAKTQKHFYHQQLEFGSFLLSRMLINFCSIFDLSSEF
                     ILAFKGLGHLNELLMACNSDTEASNAHTDWLLDVYARNIKTLKKLPSVLKELPENLNV
                     CPGVHTEALLVTLKMMCQSITELS"
     exon            117..230
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            231..306
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            307..547
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            548..710
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            711..839
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            840..983
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1127
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1262
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1263..1316
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1317..1475
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1476..1639
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1640..1768
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1769..1934
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1935..2082
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2083..2228
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2229..2392
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2393..2523
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2524..2616
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2617..2799
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2800..3742
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3716..3721
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3739
                     /gene="Slf1"
                     /gene_synonym="2700017A04Rik; Ankrd32; Brctd1; Brctx;
                     C730024G01Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtttcctaga acctagttta ttggagcagg gagtcctacg gtggtagtcg tcgcccctac
       61 cgccaccacc ggcagcttcg caagacgaaa ccagcccaga agcttcggcc gggaagatgg
      121 aagatagtgc cacaaaacat atcatccaaa tgacaggatt taagatggaa gaaaaggaag
      181 ctctagtcaa attgctttta aaactagatt gcacttttat taagagtgag aaatataaaa
      241 actgtacaca tcttatagct gaacgactgt gcaagagtga gaagttttta gcagcttgtg
      301 cagcaggaaa atgggtatta acaaaggatt acataattca cagtgccaaa agtggcagat
      361 ggcttgatga aacaacttat gaatggggat ataaaattga aaaagactcc cattattcac
      421 ctcaaatgca atctgcacct aaaagatggc gtgaagagct gaaacggact ggtgctcctg
      481 gggccttcca cagatggaaa gttgttctcc ttgttagggc agataagcgg agtgactctc
      541 ttgtaagagt tttggaggct ggaaaagcaa atgtcatttt accaaaaaat tctccaagtg
      601 ggataacaca tgtgattgcc agtaatgcaa gaatcagtgc tgaaagagag caagaaaact
      661 ttaaggctcc attttatcca attcagtatt taggagattt tctattagag aaagaaattc
      721 agaatgatga acattcccaa atcagtcctg cttggaccaa atacaacaat caagaaaaag
      781 gaaatgatgt gggatttcct gaaatgaaag gtgctggaga aaacatgtat agaactcaga
      841 ataaaatgga aaatcataat aaaaatgtta gtgatagatt tgttctgagt gaacatcaca
      901 aaaaaaaatt caaagacttc agaaaagata taagatctgt taaaaagaga aatacactca
      961 gaagacatgg acttgagaat cagaaagaaa ctaagaaaaa ggataaaaat atccaaagga
     1021 gttacatttt gaggaaaaag aacaaaaaag aaggttattg caaaactgat gatgcccatg
     1081 atacaattag aagtatgtta aagaagcgtg ggcattacag agagcagaaa gaaatgaaga
     1141 atcctcttct tactgatggt accaaagaat caaagaccaa ggatgtcaag acaaatatga
     1201 atctcattga aataaaaaat gccttaaaga agcagatata caaggacata tatagagctc
     1261 aggctgtccg atacaactgc attagagtag ataaacagcc tgtatacaat gtagaggtta
     1321 aaaattctga gttccctaga ggaatattaa acttaatcga aaacctcata gagggacagt
     1381 tctttaaaga agccattgag gagctttcct ctttgcaagc tcattatatc cctcctgtgt
     1441 gccttctcca tgccattcta gagaatgttc tgcaggataa aatagacaca ttttctggtc
     1501 gatactttca tatattatca gctcttcttc atctgcatcc tccttggaag tcaccagcca
     1561 tgttaaaata ctacttagag ctatttcagt gtccaacttg tatgaaagga gcctgggatt
     1621 tcacggaggt gctcatcagg tcatgtcttt tcaatgaaga tttttgccat caaatatcag
     1681 aaaatattag tactaaggtg gtcaatctca cattgctcaa gtttttcttt aatttacttg
     1741 aaggtgaagt tcggcatttg agtcaaaagt tatgtgactg gtcagattct cagagtctaa
     1801 aagtaacaga aaaggcaatt cttcatgaaa ttttttggtc aggaagtgaa acttcaggac
     1861 ttttgacaaa accagtaaat atgcttttgg aatggactat atattctcac aaggaaaaat
     1921 gcaagtctaa tgatgtcttc aaacatgaac tatcttactt actgactgga attcttggtg
     1981 cagcagtaga ttactggatc ttccttggta ttcagatggg tagaaatgtg atccgacata
     2041 tgtctgatga cttaggaagt tatatttccc tttcctgtga tgacttttct tcaaaagaac
     2101 tagagatctt catttgttcc ttttcatctt cctggcttca aatgtttgtt gcagaagcaa
     2161 tttttaaaaa gctgtgctta cagggcccca ctagtacgtg cactgagcca ctctctcttc
     2221 agaaaataat agattcctat ttgccaattt tgggaaaaat ggacatacat ggggctggaa
     2281 agatgcagag tccaaaaaaa ctctgccagc ggccttgcct agagtctcaa agagcattac
     2341 taatgctgaa tggtgcaaaa cggaaacaag cagaaggtcg gccagagctc ctagagttaa
     2401 accgtgctaa atgttcctca tcattgaaaa aattgaaaaa gaagtcagag gaattgtcat
     2461 gttccaagga gaattgccca tctttggtta caaagatgaa ttttcataaa actaatctga
     2521 aaggggaaac agctctgcat agagtttgca taaaaaacca agtggagaaa ttgattatcc
     2581 ttctgtcttt gccaggaata gacatcaatg ttaaagacaa tgctggctgg acgcctttgc
     2641 atgaagcctg caactatggc aacacggagt gtgtccagga aattctgcag cgttgtccag
     2701 aggtggatct gctcactcaa gtggacgggg tgacgccttt gcatgatgcg ctgtcaaacg
     2761 gacatgtgga gattggcaag ctgcttctac agcgtggggg cccagaactt ttacagcaga
     2821 ggaactctaa gggggagttg cccttggatt atgtgctgtc ccctaaggac aaggaagaac
     2881 tatttgccat tacaaatata gacgatacag tggacaactt tcatgctaag acacagaaac
     2941 atttttacca ccaacagctt gaatttggtt cgtttttact tagtaggatg ttgattaatt
     3001 tttgttcaat atttgatttg tcctcagaat ttattctagc tttcaaaggg ttaggtcatc
     3061 taaatgagtt gcttatggca tgcaatagtg atacagaagc cagcaatgca catactgact
     3121 ggttattgga tgtttatgct aggaatataa agacattaaa gaagctccca agtgttctta
     3181 aagagctgcc tgagaatcta aatgtatgtc ctggagtgca tactgaggcc ttactggtga
     3241 cactgaaaat gatgtgtcag tcaatcacag agctgtcatg atgccagaaa gtatgaatca
     3301 gatgtctgaa cgtgcaacat gctttgtcat ttagtatatc catagcttat ggaaaaaata
     3361 ttaatttcag ttactcactg acagcaaagt ttcatagcac ttataaaaca tctacagatc
     3421 taaaatatgg gctcaggatt taactcagaa acatacaata agaaaatgaa gtagttttgt
     3481 tcggtataaa tggtttcact gatttttaaa aaacagattt gttcttcaaa tatttattta
     3541 tattatatat atagaaaatt aatttaaata ttttttcaag tcaaaatgtc ctttcctctg
     3601 agtgctacag gtctgaaaat catggcaagg atattcattc aaatgtgctt ctatatacat
     3661 gtaaaagttg tttgttcttt atatttaaga tgcatttgct tttttgtgtt tctaaaataa
     3721 acctttctag gactttaaat ta
//
