LOCUS       NM_011990               9227 bp    mRNA    linear   ROD 17-SEP-2024
DEFINITION  Mus musculus solute carrier family 7 (cationic amino acid
            transporter, y+ system), member 11 (Slc7a11), mRNA.
ACCESSION   NM_011990
VERSION     NM_011990.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9227)
  AUTHORS   Wang,J., Yi,H., Li,J., Yang,Y., Sun,G., Xue,Y. and He,L.
  TITLE     P62-autophagic pathway degrades SLC7A11 to regulate ferroptosis in
            doxorubicin-induced cardiotoxicity
  JOURNAL   Life Sci 356, 122981 (2024)
   PUBMED   39147314
  REMARK    GeneRIF: P62-autophagic pathway degrades SLC7A11 to regulate
            ferroptosis in doxorubicin-induced cardiotoxicity.
REFERENCE   2  (bases 1 to 9227)
  AUTHORS   Lv,T., Fan,X., He,C., Zhu,S., Xiong,X., Yan,W., Liu,M., Xu,H.,
            Shi,R. and He,Q.
  TITLE     SLC7A11-ROS/alphaKG-AMPK axis regulates liver inflammation through
            mitophagy and impairs liver fibrosis and NASH progression
  JOURNAL   Redox Biol 72, 103159 (2024)
   PUBMED   38642501
  REMARK    GeneRIF: SLC7A11-ROS/alphaKG-AMPK axis regulates liver inflammation
            through mitophagy and impairs liver fibrosis and NASH progression.
REFERENCE   3  (bases 1 to 9227)
  AUTHORS   Beckers,P., Belo Do Nascimento,I., Charlier,M., Desmet,N.,
            Massie,A. and Hermans,E.
  TITLE     Implication of system xc- in neuroinflammation during the onset and
            maintenance of neuropathic pain
  JOURNAL   J Neuroinflammation 21 (1), 117 (2024)
   PUBMED   38715127
  REMARK    GeneRIF: Implication of system xc[-] in neuroinflammation during
            the onset and maintenance of neuropathic pain.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 9227)
  AUTHORS   Cao,N., Zhang,F., Yin,J., Zhang,J., Bian,X., Zheng,G., Li,N.,
            Lin,Y. and Luo,L.
  TITLE     LPCAT2 inhibits colorectal cancer progression via the PRMT1/SLC7A11
            axis
  JOURNAL   Oncogene 43 (22), 1714-1725 (2024)
   PUBMED   38605214
  REMARK    GeneRIF: LPCAT2 inhibits colorectal cancer progression via the
            PRMT1/SLC7A11 axis.
REFERENCE   5  (bases 1 to 9227)
  AUTHORS   Yang,B., Shu,W., Hu,J., Wang,Z., Wu,J., Su,J., Tan,J., Yu,B. and
            Zhang,X.
  TITLE     Aberrant Expression of SLC7A11 Impairs the Antimicrobial Activities
            of Macrophages in Staphylococcus Aureus Osteomyelitis in Mice
  JOURNAL   Int J Biol Sci 20 (7), 2555-2575 (2024)
   PUBMED   38725861
  REMARK    GeneRIF: Aberrant Expression of SLC7A11 Impairs the Antimicrobial
            Activities of Macrophages in Staphylococcus Aureus Osteomyelitis in
            Mice.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 9227)
  AUTHORS   Sato,H., Kuriyama-Matsumura,K., Hashimoto,T., Sasaki,H., Wang,H.,
            Ishii,T., Mann,G.E. and Bannai,S.
  TITLE     Effect of oxygen on induction of the cystine transporter by
            bacterial lipopolysaccharide in mouse peritoneal macrophages
  JOURNAL   J Biol Chem 276 (13), 10407-10412 (2001)
   PUBMED   11136724
REFERENCE   7  (bases 1 to 9227)
  AUTHORS   Sato,H., Tamba,M., Ishii,T. and Bannai,S.
  TITLE     Cloning and expression of a plasma membrane cystine/glutamate
            exchange transporter composed of two distinct proteins
  JOURNAL   J Biol Chem 274 (17), 11455-11458 (1999)
   PUBMED   10206947
REFERENCE   8  (bases 1 to 9227)
  AUTHORS   Odorizzi,G., Cowles,C.R. and Emr,S.D.
  TITLE     The AP-3 complex: a coat of many colours
  JOURNAL   Trends Cell Biol 8 (7), 282-288 (1998)
   PUBMED   9714600
  REMARK    Review article
REFERENCE   9  (bases 1 to 9227)
  AUTHORS   Swank,R.T., Novak,E.K., McGarry,M.P., Rusiniak,M.E. and Feng,L.
  TITLE     Mouse models of Hermansky Pudlak syndrome: a review
  JOURNAL   Pigment Cell Res 11 (2), 60-80 (1998)
   PUBMED   9585243
  REMARK    Review article
REFERENCE   10 (bases 1 to 9227)
  AUTHORS   Swank,R.T., Reddington,M. and Novak,E.K.
  TITLE     Inherited prolonged bleeding time and platelet storage pool
            deficiency in the subtle gray (sut) mouse
  JOURNAL   Lab Anim Sci 46 (1), 56-60 (1996)
   PUBMED   8699821
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB630675.1, AB022345.1 and AC101992.11.
            
            On Nov 6, 2005 this sequence version replaced NM_011990.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY766236.1, BC141408.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                BB630675.1         2-34
            34-1796             AB022345.1         1-1763
            1797-9227           AC101992.11        159592-167022       c
FEATURES             Location/Qualifiers
     source          1..9227
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 21.72 cM"
     gene            1..9227
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /note="solute carrier family 7 (cationic amino acid
                     transporter, y+ system), member 11"
                     /db_xref="GeneID:26570"
                     /db_xref="MGI:MGI:1347355"
     exon            1..629
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /inference="alignment:Splign:2.1.0"
     CDS             353..1861
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /note="sodium independent anionic amino acid transport
                     system; amino acid transport system xc-;
                     cysteine/glutamate transporter; solute carrier family 7
                     member 11; subtle gray protein"
                     /codon_start=1
                     /product="cystine/glutamate transporter"
                     /protein_id="NP_036120.1"
                     /db_xref="CCDS:CCDS17335.1"
                     /db_xref="GeneID:26570"
                     /db_xref="MGI:MGI:1347355"
                     /translation="MVRKPVVATISKGGYLQGNMSGRLPSMGDQEPPGQEKVVLKKKI
                     TLLRGVSIIIGTVIGSGIFISPKGILQNTGSVGMSLVFWSACGVLSLFGALSYAELGT
                     SIKKSGGHYTYILEVFGPLLAFVRVWVELLVIRPGATAVISLAFGRYILEPFFIQCEI
                     PELAIKLVTAVGITVVMVLNSTSVSWSARIQIFLTFCKLTAILIIIVPGVIQLIKGQT
                     HHFKDAFSGRDTSLMGLPLAFYYGMYAYAGWFYLNFITEEVDNPEKTIPLAICISMAI
                     ITVGYVLTNVAYFTTISAEELLQSSAVAVTFSERLLGKFSLAVPIFVALSCFGSMNGG
                     VFAVSRLFYVASREGHLPEILSMIHVHKHTPLPAVIVLHPLTMVMLFSGDLYSLLNFL
                     SFARWLFMGLAVAGLIYLRYKRPDMHRPFKVPLFIPALFSFTCLFMVVLSLYSDPFST
                     GVGFLITLTGVPAYYLFIVWDKKPKWFRRLSDRITRTLQIILEVVPEDSKEL"
     exon            630..756
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /inference="alignment:Splign:2.1.0"
     exon            757..872
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /inference="alignment:Splign:2.1.0"
     exon            873..998
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /inference="alignment:Splign:2.1.0"
     exon            999..1098
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /inference="alignment:Splign:2.1.0"
     exon            1099..1143
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..1267
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /inference="alignment:Splign:2.1.0"
     exon            1268..1371
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /inference="alignment:Splign:2.1.0"
     exon            1372..1468
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..1618
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /inference="alignment:Splign:2.1.0"
     exon            1619..1796
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /inference="alignment:Splign:2.1.0"
     exon            1797..9227
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9157..9162
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /note="hexamer: AATAAA"
     polyA_site      9178
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
     regulatory      9205..9210
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /note="hexamer: AATAAA"
     polyA_site      9227
                     /gene="Slc7a11"
                     /gene_synonym="9930009M05Rik; sut; xCT"
                     /note="major polyA site"
ORIGIN      
        1 aaatacggag ccttccacga ggaagctgag ctggtgtgta atgatagggc agcagccgcg
       61 gctgcagcta actgactgcc cctggagccg gtgccacaca ggtgctccga ggagcaagag
      121 gagtaattat agagccagcg aaggctgaaa cacacctctg agttctcacc tgtggacaca
      181 atagtgtaga gccagtcggt gatagcaaag gggaagtcac gaccgaacag tgatcagtca
      241 cttcttagag aaacaagtta aaagggtttg ttttgttttg ttttattttg tcttgttttg
      301 tttttccccc tctgttttct ttttcatccc cctcctctgg tgtgacactg ccatggtcag
      361 aaagccagtt gtggccacca tctccaaagg aggttacctg cagggcaata tgagcgggag
      421 gctgccctcc atgggggacc aagagccacc tgggcaggag aaggtagttc tgaaaaagaa
      481 gatcactttg ctgagggggg tctccatcat catcggcacc gtcatcggat caggcatctt
      541 catctccccc aagggcatac tccagaacac gggcagcgtg ggcatgtccc tggttttctg
      601 gtctgcctgt ggagtactgt cactttttgg agccctgtcc tatgcagaat taggtacaag
      661 cataaagaaa tctggtggtc attacacata cattctggag gtctttggtc ctttgctggc
      721 ttttgttcga gtctgggtgg aactgctcgt aatacgccct ggagctactg ctgtgatatc
      781 cctggcattt ggacgctaca tcctggaacc attttttatt caatgtgaaa ttcctgaact
      841 tgcaatcaag ctcgtgacag ctgtgggcat cactgtggtg atggtcctaa atagcacgag
      901 tgtcagctgg agtgcccgga tccagatttt cctaaccttt tgcaagctca cagcaattct
      961 gataattata gtccctggag ttatacagct aattaaaggg caaacacatc actttaaaga
     1021 tgcattttca ggaagagaca caagtctaat ggggttgccc ttggcttttt attatgggat
     1081 gtatgcatat gctggctggt tttacctcaa ctttattact gaagaagtag acaaccctga
     1141 aaaaaccatc ccccttgcaa tctgcatctc catggctatc atcacagtgg gctacgtact
     1201 gacaaacgtg gcctatttta ccaccatcag tgcggaggag ctgctgcagt ccagcgccgt
     1261 ggcggtgacc ttctctgagc ggctgctggg aaaattctca ttagcagtcc cgatctttgt
     1321 tgccctctcc tgcttcggct ccatgaacgg tggtgtgttc gctgtctcca ggttattcta
     1381 cgtcgcatct cgagaagggc accttccgga aatcctctct atgattcatg tccacaagca
     1441 cactcctctg ccagctgtta ttgttttgca tcctctgacg atggtgatgc tcttctccgg
     1501 agacctctat agtcttctaa atttcctcag ttttgccagg tggcttttta tggggctggc
     1561 agtcgcagga ctgatttatc ttcgatacaa acgcccagat atgcatcgtc ctttcaaggt
     1621 gcctctcttc atcccggcac tattttcctt cacctgcctc ttcatggttg tcctctctct
     1681 ttactcggac ccattcagca ccggggtcgg ttttcttatc accttgactg gggtccctgc
     1741 atattatctc ttcattgtat gggacaagaa acccaagtgg ttcagacgat tatcagacag
     1801 aataaccaga acattacaga ttatactaga agttgtacca gaagactcta aagaattatg
     1861 aacttaatgc atcaaaagct tggccatctg cccaggattg agatacaaaa tggattttta
     1921 tttcaagaaa acacaacgtt gatgatggac taaaggaatc agttatctct attcatatcc
     1981 tctagcgtat tcaaattaat ttctgagcaa cttactggta actccatgta tttgtagcaa
     2041 gctaatatgc aagtcataca gtgaggcaag ctcacagttc ttgagtctag tgcctatctg
     2101 ctggggggaa aggaaaaaaa acctaagggc tttggtacct gggctatcat tcctctacca
     2161 cgtttcttat catgactgag aaccttgaac agaagaccaa aatggtttct gtatatatga
     2221 ggtctataaa catagcttta cctactgggg acatctatac tgtgaaagta ttttgttttt
     2281 tatttttctg gaaaaaaatg tcattattgt agcaaagaag gtagaatgac tttgatattg
     2341 acattggact cttttccctt agtgatcaac atggctgtca cttatctttc aatggcttat
     2401 actcagagca tcagaacaaa agatgaggga gtagtgtgtg tgagtgtgtg tgtgtgtgtg
     2461 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgta gcttgagatc aaattcaggg
     2521 ctttacaaaa gccagacaag cactctacca ttgaaataca catacaccct aattttccta
     2581 aatgcataaa ataagtattt ccaggggtta gtattcatga cacaatccta ggaactatgt
     2641 ttgtactaaa atcattgaga acttgttagg ttaacttcat catagctcat tgtgaggaag
     2701 ctcggtgttt gcaacatcac tgtgcattca ttgtggtttg tttttttcct gaaaatgtgt
     2761 acagtttggt atgctatcca ttggtgaacc acctctttga taatttactt cttggtggac
     2821 aaaaatgttt tcctcatcac agtacaacat cagcatggga gacattgccc ataaatctcc
     2881 aagtatcagg ctttctcttt atgagcccca tttatatgca gtgttagtaa ttactcactt
     2941 ttactttgtg gctgttttca cctggtgatg agtttttgac agtgtgtgca ttctctttac
     3001 agttctgtta aaatatgcct ctggttaaaa ctatctggat caattaggaa aagtgcagat
     3061 ttacataaaa actatgaacg aaatgccact gcttcgtgaa aatctaggct gtttcagtca
     3121 tttcttcact ttagttataa ttcaatttgc aaaagaggga gatgtgacca aacccattga
     3181 aggagagtct tcagtacggt tgttcagcta gctacatatg ttaaatcaga gttagaaaac
     3241 agtagccata ttcaaatgga attaatgcaa tggtgggatt ttcaaaatat ttttctaaca
     3301 tccaaaaatt aaatgctcag catagtcaca gttaatttca tctcttatat tctgaccacg
     3361 taaaaccaca atgttttaaa aaattatcct gaactgggca ttggccaggt caccaccaag
     3421 taccacagtg ggaggctggt agttaatgcc aaccttgaag ccagtggggc accaatctat
     3481 aaactggatg ctgtgcttgg tcttgatggt ggcaatggca gcattgacta tttgggaccc
     3541 acataaccac ggtacagcag gcagcaagcc atgtatttac catggcaagg gtcatatttc
     3601 accatctggt tggctggctc aaagcaggca ttggtgatct ctgctacaga aagctgctca
     3661 tggtaggctt tctcagcaga gatgacaggg gcataagtgg ccagagggaa gtggatacga
     3721 gggtagggta ccaggttggt ctggaattct gtcagatcaa cattcagggc ccataatcaa
     3781 cggagagaca ctccatcagc agggaggtga agacagagcc agttccccca ccaaagctgt
     3841 ggaaaaccaa gaagccctgg agatccgtgc actggtcagc cagcttatga atcctgtcca
     3901 ggacaaggtc aatgacctcc ttgccagtgg tgtagcggcc acgggcatag ttattggcag
     3961 catcctcctt gcctgtgatg agctgctcag ggtggaagag ctggcagtag gtgtcagtga
     4021 gaacttcatt gatgactgtg ggttccaggt ctatgaacac tgcctgacgc acatgcttgt
     4081 catctcctgt ctcactgaag aaggtgttga aggagtcatt tcctccccca atggtcttgt
     4141 cacttggcat ctggccatca ggctggatgc catgtaccag gcagtagagc ttccagtagg
     4201 cattgctgat ctggacacca gcctggacaa catggatgga gatgcactca cgcatgatat
     4261 caattgctta gagggtgagg gtgagagaga gaagcagaca ctgggtctcg attaccattc
     4321 ccgacaacta agagtcgaca taagtaacgc aatgaggcca taaaacaggt tttaaattca
     4381 ggaatactcc tccacacttg taatatgtgt ttttatacaa agtaaatgtt tctcatattt
     4441 tagatttata tatgtatata cacatgcaat tacatgggtc aatgtttgtg ctgatgtaca
     4501 tattcgaatg tttatataaa accatgattt gagtattaca acaccaagct aaatgcagcc
     4561 caaacagttt aaaatataca atactctatt ttcaaatatt ctttgtttag tatacaaagc
     4621 acctgacatg taacttttaa agcatctcat aaagatttcc aatgcttaga tgcaatttta
     4681 ttctccttgc atgattataa gtatttccat tgactgatat tcttatagca cttctttatc
     4741 tcttctttaa agcagtagat tctctccttt gattttaagt ggctcttgga aatggttggc
     4801 tctgctcagc agacaacagg tcctgctctt gtcttttatc aggagattga acatttctct
     4861 tagtaagcat ggctgggtcc aggtccattt gtgaggtcat gagtgtccac ccacagtctg
     4921 tgcatatttt ctccccagcc ctgcaggtac aggatcagga cagctgatag ggttatttct
     4981 ctgtgctctg cagatactat aacactaaaa catgcatata ggaacattct gcttttcaga
     5041 ttgccttacg tgtgtctgct tagattgttt tcttaattgc catttgaaca gcaacagatg
     5101 gttaccatga gtacaactct ttactagacg tcatagtaag ttgagatcag cctttgggaa
     5161 ctccctgttt catctcaatt tataggtgaa tgggatgcta agaaagcctg cttctctccc
     5221 tttttttaat atctgataac tgaggtgtga aaagacaacc caaggtccct accacatttt
     5281 accatcatgc cacaaagaag ggaaatttta atgcttgtct cttgaatgta aatgaacacc
     5341 ctgagaagct aatgagacag gcatttgggt gcctccaatg cacctaagct ccttccaaga
     5401 ccccatccct agcactcact tgcaaagatt ttatattttt aaaagaccag ggattggggc
     5461 taaagaggtg gcttggcttc gaagaacact taacaccttt acagagaata catatggcag
     5521 ctatcaccat aggtaactac agttccaggg gacccagtgt cctcttgtat gtacaggcat
     5581 gcacatagtg cacatatatc catgcagaca aaatactcgt atctattaaa tgtatgtgaa
     5641 aaacttttag aaacaaggaa aagtacatag actttggaca ctgtaatatc tatattttct
     5701 ttgtgaataa ggtaaaagta gtccccatta tcttcccatt agaagtaatc ataggatatt
     5761 tgtaaaacac atgttaaata tataaattct atgttaatta aaatatacac ataaaaacca
     5821 ctagtggctg tctcataagt tctatgtgat acagaagtca gtgatgtcaa ctgggttaag
     5881 tcatgaataa tagaaaagaa atgaatgagg ttttatttgt agtttttttt tctttcctta
     5941 tttttagaga gaaatacatt tgagatttca atggagatga ctcaagaaac tttattttat
     6001 ttgaatatca ttggcttcct gatgcactct gtgttggtgc tgatagaatg caggtgatct
     6061 cttatgtccc taatcattca agctgagaat taggtcatgg cactgtgtaa tggcaaggag
     6121 attatagaga aggtagcaag tcatttgcat agcttctgtt tacattatat atggatagaa
     6181 gaatgattgc ctgcatatgt agtttaccta aatttcccca caaacagtat ttcaaaagtt
     6241 cattttcaat atatttgaca gctggaaagt gtgacctcta ggtaggcctc cgattgctaa
     6301 tattatactt taaagtagat gatttaatag ccaattttac aaacaatcct ttattttatt
     6361 gaattttcca attatttggt atctaaaaat aaatgatctg tccctatcat gtcacgtaac
     6421 tggtgcaaat gcacatgtta tgggcacata ggaagctcac ctgttcattt tatgaggcca
     6481 tgtccttctt tatcaactta tgatgacact gttgcttgtt tctttccttt atcatttctg
     6541 ttctatttac ataaaataac agttcgctct atctcagttt tcgatattaa tgccttcaag
     6601 atggtagcta tagaaagact cacttcctaa gatttttctt agtgaaaaga tctgttcctc
     6661 ccttctcttc cttatttcca gttgacttga aatgcagagg agggtggttt cagcctgcag
     6721 acaactccct gctacttggt gtgtgtattt cagtctgttt cgatcagagg ttcttttgtg
     6781 gtgtcagtcc ccacctgcac aattttatag gcaatacttt caaagaccca gttactcatt
     6841 atgcatctga gagccatgtg gctggcagag gcaattcaaa aggaagcaca cttcccccct
     6901 cccccgcccc caacacacac tcgcatacac actacagatt tttagagtga atagattact
     6961 gtttagagga cctgcttgct atgtccttac tacctcttga tgaagccact aaaagcagtg
     7021 ttgaaggcag gggagagaaa gcgaagacta atgctcagtt atctctttca cagcgataac
     7081 tgggttctga gcactttgtg tgatggggtt ttcacagcat cttgtgggaa aatgtgttag
     7141 gtctttggat ggataagtgg gttgcttgtg gtcacacctt actcttacta atgaccctta
     7201 ataaccatag actcagatct acagtcatat cctaccagga gacaagacac tgcaggttcc
     7261 tacttgtaaa attggaagga tcttgtttca aagaatttag gaattattct atgcctataa
     7321 tctctctgtc actctactta ctaaataata taatgttatc ttagagtaga agagtacttt
     7381 gagtaaataa aagaaaaaca ttatttgtaa tgaatgaaag tttatagcag gaaaatttac
     7441 attaaatagc ttagtattct aatgatttca gatactagtc cctagcattt ttttttaatc
     7501 taagaccaaa acattctgtg tcataatacc tatatttttc tatatgtctg gatgtatatc
     7561 acagcgacta cttcacaagc caccaaaatt cttttatgat tctgagcaac ctaaccactt
     7621 cttggagaaa cttgtcagac aatagtttta tctgagaatt tcattactgc tgctgtagaa
     7681 aaaaaaatgc aaccaaaatt ttaactaggt tcttcttggt attatgtttg ttcagagagt
     7741 tttgccctta ggaagcttct agaatcagca gcaaccagag tatatacttt acttcaaagc
     7801 ttgcatattt tagacacagg catggaccct gaatttctgt ttctgttagt gcgtttcagt
     7861 acaatggtaa tgagggtcag tagttttcaa caagtgggaa ttttgcaacg ataagtatcc
     7921 ggtatgtttt ctatttgggc tgtacaagat aaaacaaaac aaaacaaaac aaaacaaaac
     7981 aaaacaaaac aaaacaaacg aggtagttaa atgtctcact aatgctgtgc aggatgctgg
     8041 gagaacttga tttgtcttcc ctctctggta agacttgaac cctgaatttc atagcatgta
     8101 attcttactg tgtagtgaga attacatggt agtcatgcac tgggaaagga agattttagt
     8161 tattaattca gaactcagtc caatcaatca tctttatttt aacatatctg tatgtacttc
     8221 attaaaatgt gagtttgtaa gttttatcta aatatttagc ctactaatgt ttttgctttt
     8281 tacatctacg agtagaaaaa ttcataggtg tgctggtatg ttgatagtaa tgtatcagga
     8341 gctttatgta aatgtactta gctttgctta cattcttctg caagcatcat taactggttc
     8401 tggtggaatc actttagccc agtggtagtc agtttaatct tatgactacc ttcacaactg
     8461 tcctttgatc tgtgctccag atatatttta caaacttgct aagctctgtg ttggatctag
     8521 actgtgtttc tgatgacctt agaacattct ccatgtagga gcatggcacc tttgttctgg
     8581 tgatctcgat acaggattgg aaacacactg cctagacaaa aatggtaccc tgtgttctct
     8641 gcgttcctca cgtctggcta agttctttac catggcattg cgatgttgaa ccttggggaa
     8701 ggtgatggct gtattttgta caaatggtga atacttaaaa gggcaaggtg gttttgatac
     8761 acagatgctg agtggtgagt tgtgagcaca gcatagagat gtatctttga attccttggc
     8821 acgagtgtac aaacatgtga tgtgtgagat aaagcaggtt ccacagcgaa gtgagctccc
     8881 tcttgggaga gtgctgctgc aacaaactca ttgctcgatg gtatttgtgc gctatttgta
     8941 ggactggaaa agcacagtgg aacaaatgta cttcccgatg ggaattcttg ttcatctttt
     9001 tgtatggatg cattggtgca gtatgatgtc acaaaaattt gcattgttga attacatttc
     9061 atttgcggag ctggccactt gttaatgctt ctagctgctt ctctatatgt ctgtgtttgt
     9121 atatttttac ttgaaaatac ttcaaatgga catttgaata aatatttcat agtttacata
     9181 ttaagcatca tgtttctttt ctataataaa tactgcttta agctgaa
//
