LOCUS       NM_001410447            6249 bp    mRNA    linear   ROD 16-OCT-2024
DEFINITION  Mus musculus solute carrier family 6 (neurotransmitter transporter,
            taurine), member 6 (Slc6a6), transcript variant 3, mRNA.
ACCESSION   NM_001410447
VERSION     NM_001410447.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6249)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6249)
  AUTHORS   Pulcrano,S., De Gregorio,R., De Sanctis,C., Volpicelli,F.,
            Piscitelli,R.M., Speranza,L., Perrone-Capano,C., di Porzio,U.,
            Caiazzo,M., Martini,A., Giacomet,C., Medina,D., Awatramani,R.,
            Viggiano,D., Federici,M., Mercuri,N.B., Guatteo,E. and
            Bellenchi,G.C.
  TITLE     miR-218 Promotes Dopaminergic Differentiation and Controls Neuron
            Excitability and Neurotransmitter Release through the Regulation of
            a Synaptic-Related Genes Network
  JOURNAL   J Neurosci 43 (48), 8104-8125 (2023)
   PUBMED   37816598
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6249)
  AUTHORS   Li,C., Zhou,Y., Niu,Y., He,W., Wang,X., Zhang,X., Wu,Y., Zhang,W.,
            Zhao,L., Zheng,H., Song,W. and Gao,H.
  TITLE     Deficiency of Pdk1 drives heart failure by impairing taurine
            homeostasis through Slc6a6
  JOURNAL   FASEB J 37 (9), e23134 (2023)
   PUBMED   37561545
  REMARK    GeneRIF: Deficiency of Pdk1 drives heart failure by impairing
            taurine homeostasis through Slc6a6.
REFERENCE   4  (bases 1 to 6249)
  AUTHORS   Singh,P., Gollapalli,K., Mangiola,S., Schranner,D., Yusuf,M.A.,
            Chamoli,M., Shi,S.L., Lopes Bastos,B., Nair,T., Riermeier,A.,
            Vayndorf,E.M., Wu,J.Z., Nilakhe,A., Nguyen,C.Q., Muir,M.,
            Kiflezghi,M.G., Foulger,A., Junker,A., Devine,J., Sharan,K.,
            Chinta,S.J., Rajput,S., Rane,A., Baumert,P., Schonfelder,M.,
            Iavarone,F., di Lorenzo,G., Kumari,S., Gupta,A., Sarkar,R.,
            Khyriem,C., Chawla,A.S., Sharma,A., Sarper,N., Chattopadhyay,N.,
            Biswal,B.K., Settembre,C., Nagarajan,P., Targoff,K.L., Picard,M.,
            Gupta,S., Velagapudi,V., Papenfuss,A.T., Kaya,A., Ferreira,M.G.,
            Kennedy,B.K., Andersen,J.K., Lithgow,G.J., Ali,A.M.,
            Mukhopadhyay,A., Palotie,A., Kastenmuller,G., Kaeberlein,M.,
            Wackerhage,H., Pal,B. and Yadav,V.K.
  TITLE     Taurine deficiency as a driver of aging
  JOURNAL   Science 380 (6649), eabn9257 (2023)
   PUBMED   37289866
REFERENCE   5  (bases 1 to 6249)
  AUTHORS   Hosoi,Y., Akita,T., Watanabe,M., Ito,T., Miyajima,H. and Fukuda,A.
  TITLE     Taurine depletion during fetal and postnatal development blunts
            firing responses of neocortical layer II/III pyramidal neurons
  JOURNAL   Front Mol Neurosci 15, 806798 (2022)
   PUBMED   36466806
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6249)
  AUTHORS   Vinnakota,S., Qian,X., Egal,H., Sarthy,V. and Sarkar,H.K.
  TITLE     Molecular characterization and in situ localization of a mouse
            retinal taurine transporter
  JOURNAL   J Neurochem 69 (6), 2238-2250 (1997)
   PUBMED   9375654
REFERENCE   7  (bases 1 to 6249)
  AUTHORS   Guthridge,M.A., Seldin,M. and Basilico,C.
  TITLE     Induction of expression of growth-related genes by FGF-4 in mouse
            fibroblasts
  JOURNAL   Oncogene 12 (6), 1267-1278 (1996)
   PUBMED   8649829
REFERENCE   8  (bases 1 to 6249)
  AUTHORS   Naylor,S.L., Carritt,B., Boileau,C., Beroud,C., Alexander,C.,
            Allderdice,P., Alimov,A., Ashworth,T., Bonifas,J., Bugert,P.,
            Buys,C.H., Chipperfield,M.A., Deng,G., Drabkin,H., Gemmill,R.M.,
            Grompe,M., Joensuu,T., Jonasdottir,A., Gizatullin,R., Krols,L.,
            Leach,R.J., Lott,S.T., Killary,A., Martinsson,T., Messiaen,L. et
            al.
  TITLE     Report of the sixth international workshop on human chromosome 3
            mapping 1995
  JOURNAL   Cytogenet Cell Genet 72 (4), 255-270 (1996)
   PUBMED   8641130
REFERENCE   9  (bases 1 to 6249)
  AUTHORS   Patel,A., Rochelle,J.M., Jones,J.M., Sumegi,J., Uhl,G.R.,
            Seldin,M.F., Meisler,M.H. and Gregor,P.
  TITLE     Mapping of the taurine transporter gene to mouse chromosome 6 and
            to the short arm of human chromosome 3
  JOURNAL   Genomics 25 (1), 314-317 (1995)
   PUBMED   7774940
REFERENCE   10 (bases 1 to 6249)
  AUTHORS   Liu,Q.R., Lopez-Corcuera,B., Nelson,H., Mandiyan,S. and Nelson,N.
  TITLE     Cloning and expression of a cDNA encoding the transporter of
            taurine and beta-alanine in mouse brain
  JOURNAL   Proc Natl Acad Sci U S A 89 (24), 12145-12149 (1992)
   PUBMED   1465453
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC162914.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784644.879818.1,
                                           SRR17784650.84874.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-205               AC162914.2         45856-46060
            206-249             AC162914.2         60741-60784
            250-366             AC162914.2         73264-73380
            367-606             AC162914.2         85034-85273
            607-741             AC162914.2         86594-86728
            742-976             AC162914.2         87764-87998
            977-1109            AC162914.2         96843-96975
            1110-1244           AC162914.2         101629-101763
            1245-1348           AC162914.2         102701-102804
            1349-1473           AC162914.2         102930-103054
            1474-1586           AC162914.2         106669-106781
            1587-1724           AC162914.2         110085-110222
            1725-1827           AC162914.2         111479-111581
            1828-1928           AC162914.2         112025-112125
            1929-2099           AC162914.2         114039-114209
            2100-6249           AC162914.2         116666-120815
FEATURES             Location/Qualifiers
     source          1..6249
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 40.73 cM"
     gene            1..6249
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /note="solute carrier family 6 (neurotransmitter
                     transporter, taurine), member 6"
                     /db_xref="GeneID:21366"
                     /db_xref="MGI:MGI:98488"
     exon            1..205
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /inference="alignment:Splign:2.1.0"
     exon            206..249
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /inference="alignment:Splign:2.1.0"
     exon            250..366
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /inference="alignment:Splign:2.1.0"
     exon            367..606
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /inference="alignment:Splign:2.1.0"
     CDS             378..2243
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /note="isoform a is encoded by transcript variant 3;
                     sodium- and chloride-dependent taurine transporter; solute
                     carrier family 6 member 6; taurine/beta-alanine
                     transporter"
                     /codon_start=1
                     /product="sodium- and chloride-dependent taurine
                     transporter isoform a"
                     /protein_id="NP_001397376.1"
                     /db_xref="GeneID:21366"
                     /db_xref="MGI:MGI:98488"
                     /translation="MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEADGKPPQREKW
                     SSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEVIIG
                     QYTSEGGITCWEKICPLFSGIGYASIVIVSLLNVYYIVILAWATYYLFHSFQKDLPWA
                     HCNHSWNTPQCMEDTLRRNESHWVSLSTANFTSPVIEFWERNVLSLSSGIDNPGSLKW
                     DLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGEGIKF
                     YLYPDISRLGDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNS
                     GTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFF
                     IMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAILCSISYLLGLTMVTEG
                     GMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSW
                     AVITPALCVGCFVFSLVKYVPLTYNKVYRYPDWAIGLGWGLALSSMLCIPLVIVILLC
                     RTEGPLRVRIKYLITPREPNRWAVEREGATPFHSRVTLMNGALMKPSHVIVETMM"
     exon            607..741
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /inference="alignment:Splign:2.1.0"
     exon            742..976
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1109
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /inference="alignment:Splign:2.1.0"
     exon            1110..1244
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..1348
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /inference="alignment:Splign:2.1.0"
     exon            1349..1473
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /inference="alignment:Splign:2.1.0"
     exon            1474..1586
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /inference="alignment:Splign:2.1.0"
     exon            1587..1724
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /inference="alignment:Splign:2.1.0"
     exon            1725..1827
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /inference="alignment:Splign:2.1.0"
     exon            1828..1928
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /inference="alignment:Splign:2.1.0"
     exon            1929..2099
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /inference="alignment:Splign:2.1.0"
     exon            2100..6249
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6223..6228
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /note="hexamer: AATAAA"
     polyA_site      6249
                     /gene="Slc6a6"
                     /gene_synonym="Taut"
                     /note="major polyA site"
ORIGIN      
        1 ggagagctgc ctgttcagac aacagacacg cgaggtcagg gagaagccgc ttataaatta
       61 ccgcttcctc cgcgccgccg ccagcgtcgt gctccgggac ctggttgctg ccgagctccc
      121 gtgcccagcc gccaacgccg cgatcgccgc cagtcccgcc agcctcgcca gccccgggcc
      181 atccgctgtg ggcttagcca cccaggtgca gaaccagtgc cacagcctct tcagaggagc
      241 atctcaagcc caagcagtag ctggtgttag gcaccatctt gtagccctgg aagccgctac
      301 caccgccacc cgctgcacca acgtccgtca gcctgacaga gttagatatg actcccgtgc
      361 acccagaaaa cgaagagatg gccacgaagg agaagctgca atgtctgaaa gacttccaca
      421 aagacatcct gaagccttct ccagggaaga gcccaggcac acggcctgaa gatgaggcgg
      481 acgggaagcc ccctcagagg gagaagtggt ccagcaagat cgactttgtg ctgtctgtgg
      541 ccggaggctt cgtgggtttg ggcaacgtct ggcgtttccc gtacctctgc tacaaaaatg
      601 gtggaggtgc gttcctcata ccgtatttta ttttcctgtt tgggagcggc ctgcctgtgt
      661 ttttcttgga ggtcatcata ggccagtaca catcagaagg gggcatcacc tgctgggaga
      721 agatctgtcc tttgttctct ggcattggct acgcatccat cgtcattgtg tccctcctga
      781 acgtgtacta catcgtcatc ctggcctggg ccacatacta cctattccac tctttccaga
      841 aggatcttcc ctgggcccac tgcaaccata gctggaacac accacagtgc atggaggaca
      901 ccctgcgtag gaacgagagt cactgggtct cccttagcac tgccaacttc acctcacccg
      961 tcatcgagtt ctgggagcgc aatgtgctca gcctgtcctc cggaatcgac aacccaggca
     1021 gtctgaaatg ggacctcgcg ctctgcctcc tcttagtctg gctcgtctgt tttttctgca
     1081 tctggaaggg tgttcgatcc acaggcaagg ttgtctactt caccgctact ttcccgtttg
     1141 ccatgcttct ggtgctgctg gtccgtggac tgaccctgcc aggtgctggt gaaggcatca
     1201 aattctacct gtaccctgac atcagccgcc ttggggaccc acaggtgtgg atcgacgctg
     1261 gaactcagat attcttttcc tacgcaatct gcctgggggc catgacctca ctgggaagct
     1321 ataacaagta caagtataac tcgtacaggg actgtatgct gctgggatgc ctgaacagtg
     1381 gtaccagttt tgtgtctggc ttcgcaattt tttccatcct gggcttcatg gcacaagagc
     1441 aaggggtgga cattgctgat gtggctgagt caggtcctgg cttggccttc attgcctacc
     1501 caaaagctgt aaccatgatg ccgctgccca ccttttggtc tattctgttt ttcattatgc
     1561 tcctcttgct tggactggac agccagtttg ttgaagtcga aggacagatc acatccttgg
     1621 ttgatcttta cccgtccttc ctaaggaagg gttatcgtcg ggaaatcttc atagccatct
     1681 tgtgtagcat cagctacctg ctggggctga cgatggtgac ggagggtggc atgtatgtgt
     1741 ttcaactctt tgactactat gcagctagtg gtgtatgcct tttgtgggtt gcattctttg
     1801 aatgttttgt tattgcctgg atatatggcg gtgataactt atatgacggt attgaggaca
     1861 tgattggcta tcggcctggg ccctggatga agtacagctg ggctgtcatc actccagctc
     1921 tttgtgttgg atgtttcgtc ttctcgcttg tcaagtatgt acccctgacc tacaacaaag
     1981 tgtaccggta cccggattgg gcaattgggc tgggctgggg cctggccctt tcctccatgc
     2041 tgtgtatccc cttggtcatt gtcatcctcc tctgccggac ggagggaccg ctccgcgtga
     2101 gaatcaaata cctgataacc cccagggagc ccaaccgctg ggctgtggag cgtgaagggg
     2161 ccacaccctt tcactcccga gtaaccctca tgaacggcgc actcatgaaa cccagtcacg
     2221 tcattgtgga gaccatgatg tgaggtccgg gccatgtgac aggcgccgct ttcctgctgt
     2281 ttactaacgt tagattctca taggaccagg tttacagagc tttatatttg tactaggatt
     2341 ttttttttta attgtcacag aaaatgttac tctatgtgtg tgtgtatgtg tatcgtgtat
     2401 gtctgtatat gtgtgttttg ttttgtttgg gggatatttt gtacaaaaag aaaacccata
     2461 ggcctacgtc ctggggaaga ggatggactt tcatattgat ttccatgtat tttgtgggaa
     2521 cttggtaaat ttttctttgt atttttttta acatataact atatatactt agagtctgtc
     2581 atacactttg ccacttgaat tggtcttgcc agcaatggat ctcgtttttc aaaagcaatt
     2641 cttcggtgct tatatagctg gcagaaagtt ctgcccaaaa acaaatgaaa aaagagaaaa
     2701 aaaaaaaaaa cctgaatgct gggtggaatt ttcctatgat agtggataca tcttcaagaa
     2761 cggtgtagtc ccttctgagc tggttcagga ggaagaacac agctgaggag agggagcccc
     2821 ccccccccac tagctgaaca gacctgaggg gcaggagaga gcagggctat ggaccctcag
     2881 ccaacaagaa agatgccaaa atactggccc accctcagca tgaatgatag atctcagagc
     2941 agctgaagcg gttgtaccag ggccaaacgc ctgccctctt acttggaaga agacatgggt
     3001 ggtagtcagt gggactggct gaaccaccat gggtattaca ggcagggatg ggacgtctga
     3061 atgtctggtg aggatgtggc tcaggtctgg gagcctgcct ctgcaggcgt aggccgaatc
     3121 cctgtccttt cttgaacact cagtatggct gcccgaagcc aggccacagg agctgctggg
     3181 gcttcagagt gggggtcaca ctcaggaagt gtctgcggta tttgagtgga gtcatggtgg
     3241 gtggtgacca gagtattccc caagcagaat gtattttggt gagggcccgg ggtgagggag
     3301 gccagtggac caaatgatat tagcagctca ggagggtgag tgtaccccag gctggcaagt
     3361 gtaccccagg agggcactat tcttccttgc ctcttgacaa actcttgtga aagttaccac
     3421 cccagaacca tccagcagct cccagcaagg agtgctccaa gtggctgtag accctggatc
     3481 ttaaaggatc tgagttccag tacagagcca gcttggtagt gacctcagat gatttccaag
     3541 ccactgcatt ggctgttgga caggcgtttg cccccagggg acggcagagg gaaggcgaag
     3601 ggaagtttcg gtcagttgaa gctatctcca cagaagtgag gtcagtactc cagagctgcc
     3661 caatgtcagc ttctgaacca ggagagggca ctacaccttc accccagcct ccactgggcc
     3721 caactgtgcc atcctgaact tctttgacaa atgtacacat tttttcctgt ctccaaagca
     3781 atgtactctg ccaagtgacc ctctaatcct cttccagtgg ctgttgactc agccacccat
     3841 gattgtactg tgttcctgtt gtcctgtgta tttctggttg ctctcgtgtt attttgagtg
     3901 tttggagttc tccttccccg attttaccga cttgtaatgt accctggttt tctttcgttc
     3961 aacggaacct taaaagtaac cactgtgggt gactgaaaga caggtgaagt gtaagggaga
     4021 ggggggctcg tccagctgtg gcagtgtctg tggtcatgcc cgtctaccct acccctaacc
     4081 cccaccgggc acgcccctct ggcgagcctt cagtattttg ggttggcaga caaatggcac
     4141 cattctggaa atggcctgag aaaggctttt tttaatcatt cccagatcga attctagacc
     4201 aaagacacag cgggccaagt ccccaggccc tgcctggatt tggaaggcca gccgcctccc
     4261 gagcccactc cccagcagtg tcccctcacc tgtcttcagt ggcccccact ctcaccccgc
     4321 ccctgcccct gatgaccctt attgtgatgc ttgtcttttc acgtctgcat gtaagtaaca
     4381 ttttgaagta gagctcgtga ctctggtccg cctgcctcct ggagagaggg ctaagctgtt
     4441 caccaaccag cccttgcctg gaacaggcca gatcctgtcc tgcctgtcag atggagacag
     4501 gaagcaaggg acattgcctg gtttagatga ggacattagg tgggcccagg agaccctggg
     4561 agatgttatt tggtcctaag agtgatgtga cctcccaaat ggagggtccc tgctgggcac
     4621 tgtgggcagc cccagagggc cctgatccaa ggcacttatg taatcaggag aataggccta
     4681 gtgtggggac ttacactgtg agctaagtgg aactggacat ttgagtcatt tgtagcttca
     4741 ggttctccaa gacttagtag agggaaggca ggtccagggc attgtctaag taaactgtca
     4801 agccttccct gtcaaccaaa ggccagagct gatgagggcc cttgctccat attcatggaa
     4861 cacagagcaa tacccacgtg tgccagtcct taccgccctg ctcaccccgg ccccgtgcca
     4921 cccttccttc cttcctttct cctccaaagc ctttgggaac taggaattga tacaccctcc
     4981 cctcaagttg taccacagga aactgagggc caaagacatc actagtgtga agagccttag
     5041 ctagggtgta tgggcaggcc tttgacctcc atgtagccca aggctatgca ggaagtagcc
     5101 tgagagggtt tcttttccct ctctgcctct ggcctccagt cctcacctca gctccatacc
     5161 ctaccatgga aagccacgca gaccatggca gcgcatgagg agaaagcagc actcgccccc
     5221 tctgcacagg aaggggcttt ctctatcaca gtgtgtcacc accatggccg acagcattcc
     5281 agtcctgcct ctcgggacgg ggcaatgctc tagcaaccag tctaacaggt gccagcccag
     5341 ttcctctctc caagatgcag acacaagcca ggaaggcacc ttagagaagg cccctcacag
     5401 tcccactcaa acctgagacc cctgtcccta tggacactgt aaatacctct gtgtgcacac
     5461 cccttccttc atcaagcccc aaaccacaca cacaacaaaa cccagatact ccaagatgga
     5521 gaggggcatc ccggaagcca gagcagtgct ccctcctccc ctcctccatc tgatcgccta
     5581 ggagtcagac cttcacagga aactggctgt ccatgctctc tgggagggag gagtggtgtc
     5641 attgtcatta caggcatgtt ctggcatgtt ccctgaagga cagagcatct tattatatat
     5701 ttggcttcaa aatgagatgg tagttccatt ttcttttttt aaaaacaatt aatctttcca
     5761 atccctaaca actgtgactg tatttagcac aagagaaaag ctgagaacgt gggttttgcc
     5821 tccttcagaa atatgtctgg ctcatcagga cattttttaa aaacttcaaa atatttttaa
     5881 gatattttaa acttttgtaa aaaacaaaaa acaaaaaaac aaatgcacgc acacacacac
     5941 acatacaaca cacacacaca cacacacaca cacacataca cacaaagaaa aaaaacctga
     6001 aaccaatcaa gaaggggagg agcgtttgtg tttgaaggat ccttggtgtg tgacctgtct
     6061 tgcagtatac aagctctgtg tatgtttaat tacaacgacc ccgcattttg cagggtttcg
     6121 gttttttttt cctcttttgc tttttagatg aatatgtata ttgatatttt aaatccatct
     6181 ttgctttttt tagaggagtt tataatcacc ttgtaacaca acaataaaca tttccttttt
     6241 aaaatccaa
//
