LOCUS       NM_133184               2055 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus solute carrier family 5, member 4a (Slc5a4a), mRNA.
ACCESSION   NM_133184
VERSION     NM_133184.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2055)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2055)
  AUTHORS   Liu,M., Wang,Y., Ma,Y., Zhang,X., Zhang,L., Nie,L., Guo,W.,
            Zhao,D., Zhang,J., Yuan,D. and Yue,L.
  TITLE     Activation of SGLT3a in endometrial epithelial cells induces
            paracrine stromal cell decidualization
  JOURNAL   J Cell Physiol 237 (2), 1532-1546 (2022)
   PUBMED   34755904
  REMARK    GeneRIF: Activation of SGLT3a in endometrial epithelial cells
            induces paracrine stromal cell decidualization.
REFERENCE   3  (bases 1 to 2055)
  AUTHORS   Zukerman,S., Ackroff,K. and Sclafani,A.
  TITLE     Post-oral appetite stimulation by sugars and nonmetabolizable sugar
            analogs
  JOURNAL   Am J Physiol Regul Integr Comp Physiol 305 (7), R840-R853 (2013)
   PUBMED   23926132
REFERENCE   4  (bases 1 to 2055)
  AUTHORS   Barcelona,S., Menegaz,D. and Diez-Sampedro,A.
  TITLE     Mouse SGLT3a generates proton-activated currents but does not
            transport sugar
  JOURNAL   Am J Physiol Cell Physiol 302 (8), C1073-C1082 (2012)
   PUBMED   22301059
  REMARK    GeneRIF: Mouse SGLT3a did not transport sugar.
REFERENCE   5  (bases 1 to 2055)
  AUTHORS   Aljure,O. and Diez-Sampedro,A.
  TITLE     Functional characterization of mouse sodium/glucose transporter
            type 3b
  JOURNAL   Am J Physiol Cell Physiol 299 (1), C58-C65 (2010)
   PUBMED   20392930
REFERENCE   6  (bases 1 to 2055)
  AUTHORS   Endoh-Yamagami,S., Karkar,K.M., May,S.R., Cobos,I., Thwin,M.T.,
            Long,J.E., Ashique,A.M., Zarbalis,K., Rubenstein,J.L. and
            Peterson,A.S.
  TITLE     A mutation in the pericentrin gene causes abnormal interneuron
            migration to the olfactory bulb in mice
  JOURNAL   Dev Biol 340 (1), 41-53 (2010)
   PUBMED   20096683
REFERENCE   7  (bases 1 to 2055)
  AUTHORS   Tabatabai,N.M., Blumenthal,S.S., Lewand,D.L. and Petering,D.H.
  TITLE     Mouse kidney expresses mRNA of four highly related sodium-glucose
            cotransporters: regulation by cadmium
  JOURNAL   Kidney Int 64 (4), 1320-1330 (2003)
   PUBMED   12969150
REFERENCE   8  (bases 1 to 2055)
  AUTHORS   Pletcher,M.T., Roe,B.A., Chen,F., Do,T., Do,A., Malaj,E. and
            Reeves,R.H.
  TITLE     Chromosome evolution: the junction of mammalian chromosomes in the
            formation of mouse chromosome 10
  JOURNAL   Genome Res 10 (10), 1463-1467 (2000)
   PUBMED   11042146
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC140851.12.
            
            On Dec 30, 2006 this sequence version replaced NM_133184.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849377,
                              SAMN00849380 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-215               AC140851.12        152519-152733       c
            216-287             AC140851.12        151752-151823       c
            288-392             AC140851.12        149613-149717       c
            393-452             AC140851.12        146548-146607       c
            453-557             AC140851.12        143062-143166       c
            558-663             AC140851.12        137556-137661       c
            664-744             AC140851.12        136415-136495       c
            745-965             AC140851.12        133288-133508       c
            966-1101            AC140851.12        129398-129533       c
            1102-1209           AC140851.12        123558-123665       c
            1210-1360           AC140851.12        121944-122094       c
            1361-1529           AC140851.12        118365-118533       c
            1530-1745           AC140851.12        117299-117514       c
            1746-1848           AC140851.12        113584-113686       c
            1849-2055           AC140851.12        110919-111125       c
FEATURES             Location/Qualifiers
     source          1..2055
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 38.71 cM"
     gene            1..2055
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /note="solute carrier family 5, member 4a"
                     /db_xref="GeneID:64452"
                     /db_xref="MGI:MGI:1927848"
     exon            1..215
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /inference="alignment:Splign:2.1.0"
     CDS             81..2051
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /note="solute carrier family 5, member alpha 4a; low
                     affinity sodium-glucose cotransporter; sodium-dependent
                     glucose cotransporter; sodium/glucose cotransporter 3;
                     solute carrier family 5 member 4; Na(+)/glucose
                     cotransporter 3"
                     /codon_start=1
                     /product="solute carrier family 5 member 4A"
                     /protein_id="NP_573447.2"
                     /db_xref="CCDS:CCDS35941.1"
                     /db_xref="GeneID:64452"
                     /db_xref="MGI:MGI:1927848"
                     /translation="MASTASVSTSTASSELSSLSNNINNAADISVIVIYFVVVMAVGV
                     WAMLKTNRSTVGGFFLAGRSMTWWPMGASLFASNIGSGHFVGLAGTGAASGIAVTAFE
                     SHSFALLLVLGWIFVPIYIKAGVMTMPEYLKKRFGGKRLQIYLSILFLFICVILTISA
                     DIFSGAIFIKLALGLNLYLAILILLAITAIFTITGGLASVIYTDTVQAVIMLVGSFIL
                     MVFAFVEVGGYESFTEKFMNAIPSVVEGDNLTINSRCYTPQPDSFHIFRDPVTGDIPW
                     PGTAFGMPITALWYWCINQVIVQRCLCGKNLSHVKAACILCGYLKLLPLFFMVMPGMI
                     SRILYTDMVACVVPSECVKHCGVDVGCTNYAYPMLVLKLMPMGLRGLMLSVMLASLMS
                     SLTSVFNSASTLFTIDLYTKIRKKASERELLIAGRLFVSVLIVTSILWVPIVEVSQGG
                     QLVHYTEAISSYLGPPIAAVFLVAVFCKRANEQGAFWGLMVGLVMGLIRMIAEFSYGT
                     GSCLAPSSCPKIICGVHYLYFAIILFFVCILVILGVSYLTKPIPDVHLHRLCWALRNS
                     KEERIDLDAEDKEENGADDRTEEDQTEKPRGCLKKTCDLFCGLQRAEFKLTKVEEEAL
                     TDTTEKPFWRTVMNVNVILLLAVAAFFYGYFA"
     exon            216..287
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /inference="alignment:Splign:2.1.0"
     exon            288..392
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /inference="alignment:Splign:2.1.0"
     exon            393..452
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /inference="alignment:Splign:2.1.0"
     exon            453..557
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /inference="alignment:Splign:2.1.0"
     exon            558..663
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /inference="alignment:Splign:2.1.0"
     exon            664..744
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /inference="alignment:Splign:2.1.0"
     exon            745..965
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1101
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /inference="alignment:Splign:2.1.0"
     exon            1102..1209
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /inference="alignment:Splign:2.1.0"
     exon            1210..1360
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1529
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /inference="alignment:Splign:2.1.0"
     exon            1530..1745
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /inference="alignment:Splign:2.1.0"
     exon            1746..1848
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /inference="alignment:Splign:2.1.0"
     exon            1849..2055
                     /gene="Slc5a4a"
                     /gene_synonym="SGLT3-a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgaggctgat cattaactca ggacttatat ataataagag gtgtcaatgc ctgccatagg
       61 gactgcgctt gcctacagcc atggccagca cagccagtgt cagtaccagc actgcaagct
      121 cagagctgtc ttcactgtca aataacatca ataatgctgc tgacatctct gtcatcgtca
      181 tctattttgt ggtggtcatg gctgttggag tgtgggcaat gctgaagacg aaccgaagca
      241 ctgttggagg cttctttctg gcaggtcgat ctatgacttg gtggccaatg ggcgcctctc
      301 tgtttgccag caacatcggc agtggccact tcgtgggcct ggctgggaca ggcgcagctt
      361 caggaattgc tgtcacggcg tttgaatcac attcgtttgc cttgctgctg gttctggggt
      421 ggatttttgt ccccatttac atcaaggctg gggtgatgac catgccagaa tatctcaaga
      481 agcgctttgg tgggaagaga ctccagatct atctctccat ccttttcctt ttcatctgcg
      541 tgatattgac aatctcagca gacatatttt ctggagccat cttcataaag ctggctttgg
      601 gactgaacct ttacctggcc atcctcatcc tcttggctat cacagccatc ttcacaatca
      661 ccgggggctt ggcatccgtg atttacacag acaccgtcca ggctgtcatc atgttggttg
      721 ggtccttcat cctcatggta ttcgcgtttg tggaagttgg aggctacgag agctttaccg
      781 agaagttcat gaacgccatc ccgtctgtag tggaggggga caacctgacc atcaactcca
      841 ggtgctacac tcctcagccc gactccttcc acatcttccg agaccctgtc actggagaca
      901 ttccatggcc gggaactgcg tttggaatgc ctattacagc tttgtggtac tggtgcataa
      961 accaggtcat tgtacagcgc tgcttatgtg gcaagaacct gtcccacgtg aaggctgcct
     1021 gcatcctgtg tggctacctg aagctgcttc ccttattctt catggtgatg ccgggaatga
     1081 tcagtcgcat tctgtacaca gatatggtgg cctgcgttgt gccttctgag tgtgtgaagc
     1141 attgtggcgt tgatgtcggc tgcactaact atgcctaccc gatgctggtg ctgaagctga
     1201 tgcccatggg actgcgaggc ctgatgctgt cagtcatgct ggcttctctc atgagctccc
     1261 tgacctccgt cttcaacagc gccagcaccc tcttcaccat agacctgtac accaagataa
     1321 ggaagaaggc atcagagaga gagctcctga tagccggacg gctgtttgtc tctgtgctaa
     1381 ttgttaccag catcttgtgg gttcccatag tagaagtatc tcaaggtgga caactggtcc
     1441 attatacaga agcaatttca agctaccttg ggccccccat tgcagctgtc ttcctggtcg
     1501 ccgtcttctg taaaagagcc aatgaacaag gagccttctg gggtctgatg gttggattgg
     1561 tgatgggcct tatccgaatg atcgcagagt tttcttacgg gacagggagt tgtctggctc
     1621 ccagcagctg tcccaagatc atctgtggag tacactatct gtactttgcc atcatccttt
     1681 ttttcgtgtg tatattggtt atcctgggag tttcctactt aacaaaaccc attcccgatg
     1741 ttcatctgca tcgcctgtgc tgggctcttc ggaacagtaa ggaggaaaga atcgatttag
     1801 acgcagaaga caaggaggag aacggagctg atgatagaac tgaagaagac caaactgaga
     1861 aacctcgtgg atgtctcaag aagacgtgtg acctattctg tggtttgcaa agagctgaat
     1921 tcaagttgac taaagtagag gaggaagctc tgacagacac aacagagaag cccttctggc
     1981 ggacggtcat gaacgtcaat gtcatcctcc tcttggctgt agcagcgttt ttctatggct
     2041 attttgcctg aactc
//
