LOCUS       NM_009057                992 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus solute carrier family 50 (sugar transporter), member 1
            (Slc50a1), transcript variant 1, mRNA.
ACCESSION   NM_009057
VERSION     NM_009057.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 992)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 992)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 992)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 992)
  AUTHORS   Stokes,A.J., Wakano,C., Del Carmen,K.A., Koblan-Huberson,M. and
            Turner,H.
  TITLE     Formation of a physiological complex between TRPV2 and RGA protein
            promotes cell surface expression of TRPV2
  JOURNAL   J Cell Biochem 94 (4), 669-683 (2005)
   PUBMED   15547947
  REMARK    GeneRIF: RGA participates in the control of transient receptor
            potential cation channel, subfamily V, member 2 surface levels
REFERENCE   5  (bases 1 to 992)
  AUTHORS   Barnhill,J.C., Stokes,A.J., Koblan-Huberson,M., Shimoda,L.M.,
            Muraguchi,A., Adra,C.N. and Turner,H.
  TITLE     RGA protein associates with a TRPV ion channel during biosynthesis
            and trafficking
  JOURNAL   J Cell Biochem 91 (4), 808-820 (2004)
   PUBMED   14991772
  REMARK    GeneRIF: novel protein-protein interaction with TRPV2
REFERENCE   6  (bases 1 to 992)
  AUTHORS   Karim,S.A., Johnson,K.J., Griffiths,I.R. and Vouyiouklis,D.A.
  TITLE     A physical map of the genomic region on mouse chromosome 3
            containing the hindshaker (hsh) mutation
  JOURNAL   Genomics 83 (2), 225-230 (2004)
   PUBMED   14706451
REFERENCE   7  (bases 1 to 992)
  AUTHORS   Tagoh,H., Kishi,H. and Muraguchi,A.
  TITLE     Molecular cloning and characterization of a novel stromal
            cell-derived cDNA encoding a protein that facilitates gene
            activation of recombination activating gene (RAG)-1 in human
            lymphoid progenitors
  JOURNAL   Biochem Biophys Res Commun 221 (3), 744-749 (1996)
   PUBMED   8630032
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132327.3.
            
            On Aug 10, 2022 this sequence version replaced NM_009057.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X96618.1, AK014305.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-155               AC132327.3         127785-127939       c
            156-233             AC132327.3         127461-127538       c
            234-357             AC132327.3         127226-127349       c
            358-519             AC132327.3         126449-126610       c
            520-639             AC132327.3         126072-126191       c
            640-992             AC132327.3         125645-125997       c
FEATURES             Location/Qualifiers
     source          1..992
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 39.04 cM"
     gene            1..992
                     /gene="Slc50a1"
                     /gene_synonym="MmSWEET1; Rag1ap1; Rga"
                     /note="solute carrier family 50 (sugar transporter),
                     member 1"
                     /db_xref="GeneID:19729"
                     /db_xref="MGI:MGI:107417"
     exon            1..155
                     /gene="Slc50a1"
                     /gene_synonym="MmSWEET1; Rag1ap1; Rga"
                     /inference="alignment:Splign:2.1.0"
     CDS             76..741
                     /gene="Slc50a1"
                     /gene_synonym="MmSWEET1; Rag1ap1; Rga"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; RAG1-activating protein 1; probable sugar
                     transporter RAG1AP1; sugar transporter SWEET1; solute
                     carrier family 50 member 1; recombination activating gene
                     1 gene activation; recombination activating gene 1
                     activating protein 1"
                     /codon_start=1
                     /product="sugar transporter SWEET1 isoform 1 precursor"
                     /protein_id="NP_033083.2"
                     /db_xref="CCDS:CCDS17500.1"
                     /db_xref="GeneID:19729"
                     /db_xref="MGI:MGI:107417"
                     /translation="MEAGGVADSFLSSACVLFTLGMFSTGLSDLRHMQRTRSVDNIQF
                     LPFLTTDVNNLSWLSYGVLKGDGTLIIVNSVGAVLQTLYILAYLHYSPQKHGVLLQTA
                     TLLAVLLLGYGYFWLLVPDLEARLQQLGLFCSVFTISMYLSPLADLAKIVQTKSTQRL
                     SFSLTIATLFCSASWSIYGFRLRDPYITVPNLPGILTSLIRLGLFCKYPPEQDRKYRL
                     LQT"
     exon            156..233
                     /gene="Slc50a1"
                     /gene_synonym="MmSWEET1; Rag1ap1; Rga"
                     /inference="alignment:Splign:2.1.0"
     exon            234..357
                     /gene="Slc50a1"
                     /gene_synonym="MmSWEET1; Rag1ap1; Rga"
                     /inference="alignment:Splign:2.1.0"
     exon            358..519
                     /gene="Slc50a1"
                     /gene_synonym="MmSWEET1; Rag1ap1; Rga"
                     /inference="alignment:Splign:2.1.0"
     exon            520..639
                     /gene="Slc50a1"
                     /gene_synonym="MmSWEET1; Rag1ap1; Rga"
                     /inference="alignment:Splign:2.1.0"
     exon            640..992
                     /gene="Slc50a1"
                     /gene_synonym="MmSWEET1; Rag1ap1; Rga"
                     /inference="alignment:Splign:2.1.0"
     regulatory      971..976
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc50a1"
                     /gene_synonym="MmSWEET1; Rag1ap1; Rga"
                     /note="hexamer: AATAAA"
     polyA_site      992
                     /gene="Slc50a1"
                     /gene_synonym="MmSWEET1; Rag1ap1; Rga"
                     /note="major polyA site"
ORIGIN      
        1 ggagcttcgc cttccgcagc tccgggtctg agctactgga actccgcgct gggctaggga
       61 accggctccg gtgggatgga ggcgggcggc gtggcagact ctttcctttc tagtgcctgc
      121 gtgctcttca ccctgggcat gttctccact ggcctctcgg acctcaggca tatgcagagg
      181 acacggagcg tggacaacat ccagttcctg ccttttctca ccacggatgt caacaacctg
      241 agctggctga gttacggagt cttgaaggga gatgggaccc ttatcatcgt caatagcgtg
      301 ggggccgtgc ttcagactct ttatatcctg gcatatctgc actacagtcc tcagaagcat
      361 ggtgtgctcc tgcagacggc aaccctgctg gctgtccttc tcctgggtta tggctacttt
      421 tggcttctgg tgccggacct tgaggcccgg cttcagcagc taggcctctt ctgtagcgtc
      481 tttaccatca gcatgtacct ctccccactg gctgatttgg ccaagatcgt tcagactaaa
      541 tcaacccagc gcctctcctt ctccctgacc attgccacgc tcttttgctc cgcctcttgg
      601 tctatttacg ggtttcgcct ccgagaccca tacatcacgg tgcccaacct tccaggaatc
      661 ctcaccagct taatccgcct cgggcttttc tgcaagtacc ctccagagca agacaggaag
      721 taccgcctcc tgcagacctg accccaggca cccgagtgcc aactggatac caaacagagc
      781 tcctgtttct gctggtcctt gtgaccagtt ccatggatgc aataggttgt gagaaaaaga
      841 tgactttgaa actaaaggga ccaaagatct ttccttagat cagataggac ctgtgggatg
      901 aaatcacatt tttacaggag atcatctttt ctcatttcgg aggctgaggt ggtattagaa
      961 tgtgccttaa aataaactgt tccccacccc tg
//
