LOCUS       NM_001347328            2512 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus solute carrier family 4 (anion exchanger), member 1,
            adaptor protein (Slc4a1ap), transcript variant 1, mRNA.
ACCESSION   NM_001347328 XM_006503808
VERSION     NM_001347328.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2512)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2512)
  AUTHORS   Chen,J., Vijayakumar,S., Li,X. and Al-Awqati,Q.
  TITLE     Kanadaptin is a protein that interacts with the kidney but not the
            erythroid form of band 3
  JOURNAL   J Biol Chem 273 (2), 1038-1043 (1998)
   PUBMED   9422766
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC113276.9 and AC114613.12.
            
            On Nov 19, 2016 this sequence version replaced XM_006503808.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR2680377.170684.1,
                                           SRR7652917.652670.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-690               AC113276.9         13467-14156         c
            691-886             AC113276.9         12913-13108         c
            887-1009            AC113276.9         10396-10518         c
            1010-1070           AC113276.9         9118-9178           c
            1071-1210           AC113276.9         8568-8707           c
            1211-1371           AC113276.9         6946-7106           c
            1372-1441           AC113276.9         6224-6293           c
            1442-1628           AC113276.9         4827-5013           c
            1629-1740           AC113276.9         654-765             c
            1741-1984           AC114613.12        179158-179401       c
            1985-2071           AC114613.12        176805-176891       c
            2072-2142           AC114613.12        174390-174460       c
            2143-2212           AC114613.12        172289-172358       c
            2213-2512           AC114613.12        169033-169332       c
FEATURES             Location/Qualifiers
     source          1..2512
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 17.27 cM"
     gene            1..2512
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /note="solute carrier family 4 (anion exchanger), member
                     1, adaptor protein"
                     /db_xref="GeneID:20534"
                     /db_xref="MGI:MGI:1196608"
     exon            1..690
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..2262
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /note="isoform 1 is encoded by transcript variant 1;
                     solute carrier family 4 (anion exchanger), member 1,
                     adapter protein"
                     /codon_start=1
                     /product="kanadaptin isoform 1"
                     /protein_id="NP_001334257.1"
                     /db_xref="CCDS:CCDS84865.1"
                     /db_xref="GeneID:20534"
                     /db_xref="MGI:MGI:1196608"
                     /translation="MADPTPQLDAPAPQEVSSEFKKPVLPVPSAVRGKAPASSPSVSE
                     DVKKECLAAQLDSGCEEPEVPPPQPDSQETGGPPVEQLRSPRVAPASGGPTRAPPYRE
                     PSWGSPATAPYSLETLKGGTILGTRTLKDTSCCFFGRLASCDICLEHPSVSRYHAVLQ
                     HRGADPSGDSEGHEQGFYLYDLGSTHGTFLNKTRIPPRTYCRVHVGHVMRFGGSTRLF
                     ILQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEANTTEGKSSRSGQ
                     DDELGCTWGMGEDAVEDEAEENPIALDFQQDREAFYIKDPKKALQGFFDREGEELEYE
                     FDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMVQCSLEACRVLDTLGLLRQ
                     EAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLVEKKRLNRMKKAGKLDEKPETFESLVA
                     KLNDAERELAEISERLKASSKVLSEPSSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTF
                     ELRKEQQRLKGLIKLVKPAEIPELKKTELQTTNAENKTKKLALPLFGAMKGGSKFKLK
                     TGTVGKLPPKRPELPPALMQMKDEPEVEEEEEEEEEEEEKVKEEHEERVEDGGVRLLQ
                     EPELELEAAVEHPSAPSEPSCSKETKSHESISQLSQVEQSKDYQEMGKIVSSCEDPSA
                     APANEYKQDRDEPKKKKSPGPGKFPPILSSKYPEDDPDYCIWVPPEGQSGDGRTHLND
                     KYGY"
     exon            691..886
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /inference="alignment:Splign:2.1.0"
     exon            887..1009
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1070
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1210
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1371
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /inference="alignment:Splign:2.1.0"
     exon            1372..1441
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /inference="alignment:Splign:2.1.0"
     exon            1442..1628
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /inference="alignment:Splign:2.1.0"
     exon            1629..1740
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /inference="alignment:Splign:2.1.0"
     exon            1741..1984
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /inference="alignment:Splign:2.1.0"
     exon            1985..2071
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /inference="alignment:Splign:2.1.0"
     exon            2072..2142
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /inference="alignment:Splign:2.1.0"
     exon            2143..2212
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /inference="alignment:Splign:2.1.0"
     exon            2213..2512
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2491..2496
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /note="hexamer: AGTAAA"
     polyA_site      2512
                     /gene="Slc4a1ap"
                     /gene_synonym="kanadaptin"
                     /note="major polyA site"
ORIGIN      
        1 acattttgag attgcacccg gctaaggatg gctgatccta cccctcagct agatgcgcca
       61 gctccccagg aagtcagtag cgagtttaag aagccggttt taccagtgcc ttccgcagta
      121 cggggtaagg ctccggcctc cagtccctcc gtttctgagg atgtgaagaa agaatgtctc
      181 gcggcgcagc tggactctgg atgtgaggag cccgaggtcc cgccaccgca gccggacagc
      241 caggagaccg ggggtccacc ggtggagcaa ctccgctccc cgcgggtagc tcctgcgtct
      301 ggcggtccga cccgggctcc tccgtaccga gagccatcgt ggggcagccc agccacggcc
      361 ccctacagtc tcgaaaccct gaagggtggc accatccttg gcacccgcac cttgaaagac
      421 acgagctgct gctttttcgg gagacttgct agttgtgaca tatgtctgga gcatccttcc
      481 gtgtctcggt accatgctgt actacagcac cggggggcgg atcccagcgg agactctgag
      541 ggtcatgagc agggctttta tctctacgat ctgggaagta cccacggcac gttcctcaac
      601 aaaactcgca tcccaccccg cacttactgt agagtccacg tcgggcatgt aatgcgcttt
      661 ggaggcagca ctcggctctt tatccttcag ggaccagagg aagaccgaga ggcagaatct
      721 gaattaacag taacacagtt gaaggaattg cgtaaacagc agcagatatt attggagaag
      781 aagatgttag gtgaagactc agatgaagaa gaagaagcaa ataccactga agggaagagc
      841 agtagaagtg gtcaagatga tgagctgggc tgcacgtggg gaatgggaga agatgctgtg
      901 gaggatgaag ctgaagagaa ccccattgcc ttagattttc agcaggaccg ggaagcgttt
      961 tatataaagg atccaaagaa ggctcttcaa ggcttctttg accgagaagg agaagagtta
     1021 gaatatgaat ttgatgagca aggacacagc acttggctct gcagggtgag gttacctgta
     1081 gatgattcaa ctgggaaaca gctggtggct gaggccattc actcaggaaa gaaaaaggaa
     1141 gcaatggtac agtgctcgct ggaagcctgc cgggtccttg atacactggg cttgctacgg
     1201 caggaagcag tatctcggaa aaggaaagcc aagaactggg aagatgagga tttttatgat
     1261 agtgacgatg atacattcct cgatcggact ggcctggtag agaagaagcg cctgaaccgg
     1321 atgaagaagg ctgggaagct tgatgagaag ccagaaactt ttgagtcact ggttgcaaag
     1381 ttaaatgatg ccgaaaggga actcgccgaa atttctgaaa ggctcaaggc ttcaagcaaa
     1441 gttctgtcag agccatcatc tcaggactct ttagatgcat tcatgtcaga aatgaaatca
     1501 ggcagcacat tagatggggt gtcccggaag aaacttcacc tgaggacttt tgaactaaga
     1561 aaagaacaac agcgacttaa agggttaata aaacttgtaa agccggcaga gatcccagaa
     1621 ctaaaaaaga ctgaacttca gactacaaat gcagaaaaca aaactaagaa acttgcattg
     1681 cctctctttg gtgccatgaa aggaggaagc aaattcaaat taaaaactgg gacagtaggg
     1741 aagttgccac ccaagcgtcc agaactccct ccagctttaa tgcaaatgaa ggatgaacct
     1801 gaagtagagg aggaggagga agaggaagag gaggaggagg agaaagtgaa ggaggagcat
     1861 gaagaacgag tggaggatgg aggtgtcagg cttcttcagg agcctgagct ggagctggaa
     1921 gcagcagtgg agcacccgag tgctccctca gagccctcgt gctccaagga gactaaaagc
     1981 catgaaagta tatctcaact cagccaagtg gagcagagta aagattatca agagatgggc
     2041 aaaatagtgt cgtcatgtga ggacccttca gcagcaccag cgaatgaata taaacaagac
     2101 agagatgagc cgaagaaaaa gaaatctcct gggcctggca aatttccacc catcctttct
     2161 tccaaatatc ctgaggatga cccagactac tgtatatggg tcccacctga aggtcaaagt
     2221 ggagatggca gaacccatct taatgacaag tatggctact gattggctca gagtcccaaa
     2281 ggaagaccat gtggaccgca ggatgtttgg gaggaaacat caagtcatgg ccaggaatca
     2341 gatgaccgtt tgtaaaatct ggtgactggc tctttcttct gtatccctgg tttcctataa
     2401 ctccctgccc attggattct cctcaatttc cgtgtttata tttaagtgtt tgtgtatata
     2461 tgtaaaaaaa gagccatgta cactagaatc agtaaagagg catgacccat ta
//
