LOCUS       NM_145394               2589 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus solute carrier family 44, member 3 (Slc44a3), mRNA.
ACCESSION   NM_145394
VERSION     NM_145394.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2589)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2589)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB859851.1, CJ094004.1, CJ130557.1, BY735109.1, AC115727.10,
            AC105336.14, AK194277.1, AA450663.1 and CO813168.1.
            
            On Mar 24, 2009 this sequence version replaced NM_145394.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC025548.1, SRR17784650.232033.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-57                BB859851.1         61-117
            58-531              CJ094004.1         1-474
            532-648             CJ130557.1         33-149
            649-663             BY735109.1         261-275
            664-954             CJ130557.1         165-455
            955-1039            AC115727.10        51630-51714         c
            1040-1226           AC115727.10        50812-50998         c
            1227-1392           AC115727.10        39157-39322         c
            1393-1549           AC115727.10        31636-31792         c
            1550-1636           AC115727.10        27700-27786         c
            1637-1730           AC105336.14        156583-156676       c
            1731-1957           AK194277.1         1-227
            1958-2112           AA450663.1         182-336
            2113-2589           CO813168.1         201-677
FEATURES             Location/Qualifiers
     source          1..2589
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 52.94 cM"
     gene            1..2589
                     /gene="Slc44a3"
                     /note="solute carrier family 44, member 3"
                     /db_xref="GeneID:213603"
                     /db_xref="MGI:MGI:2384860"
     exon            1..184
                     /gene="Slc44a3"
                     /inference="alignment:Splign:2.1.0"
     CDS             146..2116
                     /gene="Slc44a3"
                     /codon_start=1
                     /product="choline transporter-like protein 3"
                     /protein_id="NP_663369.2"
                     /db_xref="CCDS:CCDS51060.1"
                     /db_xref="GeneID:213603"
                     /db_xref="MGI:MGI:2384860"
                     /translation="MPGTMQCLGAEYLVSAEKTRQREWRPQIYRKCTDTPWLVLFFLF
                     WTGLVFIMGYSVVAGAAGRLLFGYDSFGNVCGKKNSPVEGAPLSGQDMTLKKHVFFMN
                     ACNLEVKDRGLGPTALCVSSCPEKQLDTLEEVQLFANINGSFLCVYSLNSFNYTQSSS
                     ADTLCPRLPVPPSKPFPLFNRCIPQTPECYSLFASVLINDADALHRILSGIMAGRDTI
                     LGLCVFTFALSLAMLFAFRFISTLLIHIIISLVILGLLFVCGVLWWLYYDYTNDLSTE
                     LDTEKENMNCMLAFAIISTVVTVLLLALIFTLRKRIKLTVELLHVTNKAISSCPFLLF
                     QPLWTCAILIFFWVLWVAVLLSLGTAGTAQVMEGGQVEYKPLSGIRYMWWYHLIGLIW
                     TSEFILACQRMTVAGAMVACYFNRNQNDPPARPILSSLFVLFCYHQGTAVKGSFLLTV
                     TRIPRVIFMCIYSTLKEPQRSAWSRGEFRCSHCGLWCLLKYLYHLNQDAYTATAINGT
                     DFCTSAKDAHTIIAKNSSHLTSVNCFGNFVIFLGKVLVVCFSIFGGLMAFNYSRALQV
                     WAIPLLLVAFFACVVAHSFLSVFETALDILFLCFAVDLETNDGSSEKPYFMDPGFLSV
                     IKRTNNLNNAKSQGQKDALPNEEGTELQPIVR"
     exon            185..289
                     /gene="Slc44a3"
                     /inference="alignment:Splign:2.1.0"
     exon            290..432
                     /gene="Slc44a3"
                     /inference="alignment:Splign:2.1.0"
     exon            433..569
                     /gene="Slc44a3"
                     /inference="alignment:Splign:2.1.0"
     exon            570..663
                     /gene="Slc44a3"
                     /inference="alignment:Splign:2.1.0"
     exon            664..824
                     /gene="Slc44a3"
                     /inference="alignment:Splign:2.1.0"
     exon            825..914
                     /gene="Slc44a3"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1039
                     /gene="Slc44a3"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1226
                     /gene="Slc44a3"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1392
                     /gene="Slc44a3"
                     /inference="alignment:Splign:2.1.0"
     exon            1393..1549
                     /gene="Slc44a3"
                     /inference="alignment:Splign:2.1.0"
     exon            1550..1636
                     /gene="Slc44a3"
                     /inference="alignment:Splign:2.1.0"
     exon            1637..1774
                     /gene="Slc44a3"
                     /inference="alignment:Splign:2.1.0"
     exon            1775..2011
                     /gene="Slc44a3"
                     /inference="alignment:Splign:2.1.0"
     exon            2012..2560
                     /gene="Slc44a3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2540..2545
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc44a3"
                     /note="hexamer: AATAAA"
     polyA_site      2560
                     /gene="Slc44a3"
                     /note="major polyA site"
ORIGIN      
        1 gaaagggcgt gtctagggga ccagcgccct ggacctctag gaggcgctga gccctgctcg
       61 ccctgccgcc cctcctgggc cacttggccc ggtcgccgca cctctgtccc gtgtgcaagg
      121 cgaccaccgc cgccgccaat cccagatgcc gggtaccatg cagtgcttgg gcgccgagta
      181 cctggtttct gcagagaaaa caaggcaaag agaatggcga ccccaaattt atagaaaatg
      241 caccgataca ccgtggctag tcttgttctt tctcttttgg actggtttgg tgttcatcat
      301 gggttattcg gtggtggccg gggcagcagg aagactcctc tttggatatg acagctttgg
      361 caacgtgtgt ggcaagaaga actccccagt ggaaggagcc cccctctccg ggcaggacat
      421 gactctaaaa aaacacgtgt tctttatgaa tgcctgcaat cttgaagtca aagacagggg
      481 tcttggtccc acagccctct gtgtatccag ctgtcctgag aagcagctgg acactctgga
      541 agaggtccag ctttttgcca acatcaacgg ctctttcctg tgtgtgtata gtttgaattc
      601 cttcaactac actcagagtt caagtgcaga cacactgtgt cccaggctcc cggttcctcc
      661 aagcaagccc tttcccttat ttaaccggtg catccctcag acacccgagt gctattcctt
      721 gtttgcatca gtcttgataa atgatgcgga cgctctccat cggattctaa gtggaataat
      781 ggcgggaaga gacaccatcc tcggcctgtg tgtcttcaca ttcgccctgt ctctggccat
      841 gttgttcgcc ttccggttca tctcgaccct tctgatccac attatcatct ccttggtcat
      901 tttgggattg ctgttcgtct gcggtgtctt atggtggctg tattatgact acaccaacga
      961 cctcagtaca gaactggaca cagaaaagga gaatatgaat tgtatgctag cctttgccat
     1021 catctctaca gtcgtgacag tccttctcct ggccttgatt tttaccctca ggaagaggat
     1081 aaaattgaca gttgagcttc tccacgtcac aaacaaagcc atcagcagct gtcctttcct
     1141 gctgttccag ccactgtgga cgtgtgccat cctcattttc ttctgggtcc tctgggtggc
     1201 tgtgctgctg agcctgggca ctgctggtac tgcccaggtg atggaaggtg gccaagtgga
     1261 atataagcct ctttccggca ttcggtatat gtggtggtac catttaattg gcctcatctg
     1321 gactagcgaa ttcatccttg catgccagcg gatgactgta gcaggagcaa tggttgcttg
     1381 ttatttcaac aggaatcaaa atgaccctcc tgcccgtcca atcctttcgt ctctcttcgt
     1441 acttttctgc taccatcaag gaactgcggt gaaagggtca tttttactca ctgtgacaag
     1501 gatcccaaga gtcattttca tgtgtattta tagcactctg aaagagccgc agcgcagtgc
     1561 ttggtcaaga ggtgaattca gatgcagcca ctgtgggctt tggtgtctcc ttaaatatct
     1621 gtaccatctc aaccaggatg cgtacactgc aactgccatt aacgggacag acttttgtac
     1681 atccgcaaaa gatgcgcaca caatcatagc caagaattca agtcatctca cgtctgttaa
     1741 ctgctttgga aactttgtca ttttcctggg aaaggtgcta gtggtgtgct tcagcatttt
     1801 cgggggtctg atggcgttta actacagccg tgcgctccag gtgtgggcca tccctctgct
     1861 gctggttgcc ttttttgcct gcgtggtggc tcacagtttc ctatccgtgt ttgaaactgc
     1921 gctggatatc cttttcctgt gctttgctgt ggacctggaa acaaatgatg gatcgtcgga
     1981 gaaaccgtac tttatggacc cagggttttt gagtgttata aaacggacca acaacttgaa
     2041 caatgccaag tctcaaggac aaaaggatgc tttaccaaat gaagagggga cagaactcca
     2101 gcccattgtg agatagggac caagagaact ttgactacct gtgacaccga gacaaagtct
     2161 acagctgttt tcacgtgaac tagagcacgg aagatgttaa aactatgtct atatgcatca
     2221 atttaaaagg cacaatattg gctgggcaca gggacacaca tctgtaattc aaaactggaa
     2281 gaggctataa ggctagcctg agctacatac tcagatgtta aatgctagcc tgaatgctac
     2341 atagagacct catataaaca aacaaacaaa taaggttggc tcactggata aaggtgccag
     2401 ttgccaaccc gaggaactga ataccccagg acccacatgg taaaaggaga gaatcagttc
     2461 ctctaagttg tcctcagagc tccacatgtg aactgccccg agtgcactca ctcagcccca
     2521 ccaccaccac caaaaaataa ataaaaatgt taacacctca aaaaaaaaaa aaaaaaaaaa
     2581 aaaaaaaaa
//
