LOCUS       NM_133891               3102 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus solute carrier family 44, member 1 (Slc44a1),
            transcript variant 1, mRNA.
ACCESSION   NM_133891
VERSION     NM_133891.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3102)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3102)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3102)
  AUTHORS   Hedtke,V. and Bakovic,M.
  TITLE     Choline transport for phospholipid synthesis: An emerging role of
            choline transporter-like protein 1
  JOURNAL   Exp Biol Med (Maywood) 244 (8), 655-662 (2019)
   PUBMED   30776907
  REMARK    GeneRIF: SLC44A1 acts as a choline transporter both in the plasma
            membrane and in the mitochondria. Novel aspects of choline
            transport regulation in the muscle, nervous system, and cancer are
            reviewed. Review.
            Review article
REFERENCE   4  (bases 1 to 3102)
  AUTHORS   Albrecht,N.E., Alevy,J., Jiang,D., Burger,C.A., Liu,B.I., Li,F.,
            Wang,J., Kim,S.Y., Hsu,C.W., Kalaga,S., Udensi,U., Asomugha,C.,
            Bohat,R., Gaspero,A., Justice,M.J., Westenskow,P.D., Yamamoto,S.,
            Seavitt,J.R., Beaudet,A.L., Dickinson,M.E. and Samuel,M.A.
  TITLE     Rapid and Integrative Discovery of Retina Regulatory Molecules
  JOURNAL   Cell Rep 24 (9), 2506-2519 (2018)
   PUBMED   30157441
REFERENCE   5  (bases 1 to 3102)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   6  (bases 1 to 3102)
  AUTHORS   Michel,V. and Bakovic,M.
  TITLE     The solute carrier 44A1 is a mitochondrial protein and mediates
            choline transport
  JOURNAL   FASEB J 23 (8), 2749-2758 (2009)
   PUBMED   19357133
  REMARK    GeneRIF: SLC44A1 mRNA and protein expression were down-regulated
            during choline deficiency.
REFERENCE   7  (bases 1 to 3102)
  AUTHORS   Yuan,Z., Wagner,L., Poloumienko,A. and Bakovic,M.
  TITLE     Identification and expression of a mouse muscle-specific CTL1 gene
  JOURNAL   Gene 341, 305-312 (2004)
   PUBMED   15474312
REFERENCE   8  (bases 1 to 3102)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 3102)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   10 (bases 1 to 3102)
  AUTHORS   Van der Bliek,A.M., Van der Velde-Koerts,T., Ling,V. and Borst,P.
  TITLE     Overexpression and amplification of five genes in a
            multidrug-resistant Chinese hamster ovary cell line
  JOURNAL   Mol Cell Biol 6 (5), 1671-1678 (1986)
   PUBMED   2431283
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK077951.1, BC113167.1, BQ031280.1 and BB271503.1.
            
            On Apr 25, 2009 this sequence version replaced NM_133891.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes isoform A.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY249865.1, BC113167.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-244               AK077951.1         1-244
            245-2660            BC113167.1         1-2416
            2661-3050           BQ031280.1         71-460              c
            3051-3102           BB271503.1         247-298
FEATURES             Location/Qualifiers
     source          1..3102
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 28.66 cM"
     gene            1..3102
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /note="solute carrier family 44, member 1"
                     /db_xref="GeneID:100434"
                     /db_xref="MGI:MGI:2140592"
     exon            1..304
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /inference="alignment:Splign:2.1.0"
     exon            305..394
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /inference="alignment:Splign:2.1.0"
     exon            395..537
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /inference="alignment:Splign:2.1.0"
     exon            538..674
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /inference="alignment:Splign:2.1.0"
     exon            675..768
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /inference="alignment:Splign:2.1.0"
     exon            769..938
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1028
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1168
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1355
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1356..1521
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1522..1678
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1679..1762
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1763..1900
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1901..2137
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /inference="alignment:Splign:2.1.0"
     exon            2138..2218
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /inference="alignment:Splign:2.1.0"
     exon            2219..3102
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3070..3075
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /note="hexamer: AATAAA"
     polyA_site      3097
                     /gene="Slc44a1"
                     /gene_synonym="2210409B22Rik; 4833416H08Rik; Cdw92; CHTL1;
                     CTL1"
                     /note="major polyA site"
ORIGIN      
        1 tttccgctgg ggagcagctg cagcagcagg agcggagccg gagccgcgca gccgccgccg
       61 ccgccgctgc cgccgccggg ggatgtggcc ggcgcctgcc ccggaccgcg cagcctcctg
      121 agttcttgcc gctgtcgccg tcgccgccgt cgctgccgag tcgtgcgggg ccaggccgcg
      181 ccctccccgg gcgcccgccg gctcgcatgc cgaggggctc cggggcgtag ctgcgcgccc
      241 ggcgccgcct ccgggctcct ccggccccgc catgggctgc tgcagctccg cctccgccgc
      301 gcagagctcc aaacgagaat ggaagccatt ggaagaccgt agctgcacag acataccatg
      361 gctgcttctc tttgttctct tctgcattgg gatgggattt atttgtggct tttcagtagc
      421 aacaggtgca gcagcaagac tagtgtcagg atacgacagc tatggaaata tctgtgggca
      481 gagaaatgca aaactggaag caataccgaa cagtggtctg gaccacaccc accggaagta
      541 tgtgttcttt ttggacccat gcaacctgga cttgataaac aggaagatca agtctatagc
      601 actgtgcgta gcagcatgtc ctcgacagga gttgaaaacc ttgagtgacg tccagaagtt
      661 tgcagagatc aatggctcag cactatgtag ctacaacata aagccttctg aatatactct
      721 gacttcaaaa tcctctggct tttgccccaa gctaccagta ccagccagtg cacctattcc
      781 attcttccat cgctgtgctc ctgtgaacat ttcctgctat gccaagtttg cagaggccct
      841 gatcaccttt gtcagtgaca atagtgtctt acacaggctg attagtggag taatgaccag
      901 caaagaaatt atattgggac tttgcttgtt atcactagtt ctgtccatga tcctgatggt
      961 gattatcagg tatatatcaa gagtgctagt gtggattcta acagttctgg tcatactggg
     1021 ttcacttggt ggcacgggtg tattatggtg gctgtatgca aagcaaagaa ggtcccccaa
     1081 agaagcagtt attcctgagc agcttcagat agctgaggac aatctgcggg cgctcctcat
     1141 ctatgccatt tcagcgacag tgttcactgt cattctcttc ctgatcatgc tggttatgcg
     1201 caagcgtgtg gctctcacca tcgccttgtt ccacgtggct ggcaaggtct tcatacactt
     1261 gcctctgtta gtcttccagc ccttctggac gttttttgct ctcgtcttat tttgggcata
     1321 ctggataatg acacttctct tccttggcac tactggcagt gctgttcaga atgagcaagg
     1381 cttcgtggag tacaaaatct ccgggccttt gcagtacatg tggtggtacc acgtggttgg
     1441 cctgatttgg atcagtgagt tcattctcgc ctgtcagcag atgactgtgg caggagctgt
     1501 ggtaacatac tactttacta gggataaacg gaatttgcct ttcacaccta ttctggcatc
     1561 agtgaatcgc cttattcgtt accacctcgg tactgtggca aaaggatcct tcattatcac
     1621 cctcgtcaaa atccccagga tggtcctcat gtatatccac agtcagctca aagggaagga
     1681 aaacgcttgt gcacgatgca tgctgaaatc ctgcatttgc tgcctttggt gtcttgaaaa
     1741 gtgcctgagc tacttaaacc agaatgcata cacagccaca gctatcaata gcaccaactt
     1801 ctgcacctca gcaaaggatg ccttcgtcat tctagtggag aacgctctgc gagtggctgc
     1861 catcaacaca gtgggggact tcatgctgtt cctaggcaag gtgctgatag tctgcagcac
     1921 cggtttggct gggattatgc tgctcaacta ccagcaagat tacacagtat gggtgctgcc
     1981 tctgatcatc gtctgcctct ttgctttcct agtcgctcat tgcttcctgt ccatttacga
     2041 aatggtagtg gatgtattgt tcttgtgttt tgccattgat acaaaataca atgatgggag
     2101 ccctggccga gaattctata tggacaaagt gctgatggag tttgtggaaa acagtaggaa
     2161 agcaatgaaa gaagccggca aaggaggcgc tgcggacgcc cgagagctaa agccgatgct
     2221 caggaaaagg tgacctgtct ctgcagattg gaagaatgga ctctaaggag gctgtttgca
     2281 caaggctctc cactcaccag ctgttgagtc tgtgcggaag acaggatctt attacttcaa
     2341 tggcagcagc gatcaagaaa gttctccaac cttgaacagc caaatggatt gactacagtg
     2401 ggggcagcta attaatgatt aatcagaagc atttgataat aatctgcctt gcagccacgc
     2461 cttcaaactt cattgttgct ttctcttctg gccttgtaat gtttgagtca agccctgctt
     2521 ctcagctagt gagcatcagc ccaaagtcag aactcacagg ggattctctg cattcatccc
     2581 gggtctgtcc tctctgactc tgctacatac agggtccatg tgggctgata actagtacca
     2641 ggggcctgct gcatgctacg cattgggatg ggtgcccgac ataatactga atcctcaaga
     2701 agccttgtca agtttgtagg tatcattgac gttttgacga tgaggaaagg agatgctcag
     2761 agagagagag atcatgtgtt gtgagtcaga tcacacagtc gataggatca gtatttcaat
     2821 tccagagccc ctccactcta acgctatgct ttgcttatta ttgctacaga gataactgcc
     2881 ctgtagtatc ccaatggata tcactcccag tctcaaattg ggctgggtat ggcggtgtat
     2941 atgcatggga agcgtcttgg ggagggtggt agaagcacaa aagaatcaca gaattatttt
     3001 ctaagcaaaa taacacttgt ttgtttatgg cccatggatc atagcttcct gtccccacct
     3061 atttttgtaa ataaagtttt atgggaacac aaccacatcc at
//
