LOCUS       NM_021398               2601 bp    mRNA    linear   ROD 18-DEC-2022
DEFINITION  Mus musculus solute carrier family 43, member 3 (Slc43a3), mRNA.
ACCESSION   NM_021398
VERSION     NM_021398.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2601)
  AUTHORS   Hasbargen KB, Shen WJ, Zhang Y, Hou X, Wang W, Shuo Q, Bernlohr DA,
            Azhar S and Kraemer FB.
  TITLE     Slc43a3 is a regulator of free fatty acid flux
  JOURNAL   J Lipid Res 61 (5), 734-745 (2020)
   PUBMED   32217606
  REMARK    GeneRIF: Slc43a3 is a regulator of free fatty acid flux.
REFERENCE   2  (bases 1 to 2601)
  AUTHORS   Furukawa J, Inoue K, Maeda J, Yasujima T, Ohta K, Kanai Y, Takada
            T, Matsuo H and Yuasa H.
  TITLE     Functional identification of SLC43A3 as an equilibrative nucleobase
            transporter involved in purine salvage in mammals
  JOURNAL   Sci Rep 5, 15057 (2015)
   PUBMED   26455426
  REMARK    GeneRIF: SLC43A3 is an equilibrative nucleobase transporter
            involved in purine salvage in mammals.
            Erratum:[Sci Rep. 2016;6:22175. PMID: 26940463]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2601)
  AUTHORS   Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H,
            Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T,
            Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P,
            Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ,
            Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD,
            Flicek P, Skarnes WC, Mallon AM and Parkinson H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 2601)
  AUTHORS   Carninci P, Waki K, Shiraki T, Konno H, Shibata K, Itoh M, Aizawa
            K, Arakawa T, Ishii Y, Sasaki D, Bono H, Kondo S, Sugahara Y, Saito
            R, Osato N, Fukuda S, Sato K, Watahiki A, Hirozane-Kishikawa T,
            Nakamura M, Shibata Y, Yasunishi A, Kikuchi N, Yoshiki A, Kusakabe
            M, Gustincich S, Beisel K, Pavan W, Aidinis V, Nakagawara A, Held
            WA, Iwata H, Kono T, Nakauchi H, Lyons P, Wells C, Hume DA,
            Fagiolini M, Hensch TK, Brinkmeier M, Camper S, Hirota J, Mombaerts
            P, Muramatsu M, Okazaki Y, Kawai J and Hayashizaki Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   5  (bases 1 to 2601)
  AUTHORS   Stuart RO, Pavlova A, Beier D, Li Z, Krijanovski Y and Nigam SK.
  TITLE     EEG1, a putative transporter expressed during epithelial
            organogenesis: comparison with embryonic transporter expression
            during nephrogenesis
  JOURNAL   Am J Physiol Renal Physiol 281 (6), F1148-F1156 (2001)
   PUBMED   11704567
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL935159.11.
            
            [WARNING] On May 25, 2023 this sequence was replaced by
            NM_021398.4.
            
            On Nov 19, 2011 this sequence version replaced NM_021398.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF188622.1, SRR5189679.108524.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-204               AL935159.11        21126-21329
            205-551             AL935159.11        22003-22349
            552-681             AL935159.11        22703-22832
            682-728             AL935159.11        25461-25507
            729-805             AL935159.11        28722-28798
            806-898             AL935159.11        28998-29090
            899-1038            AL935159.11        31320-31459
            1039-1136           AL935159.11        32815-32912
            1137-1355           AL935159.11        34453-34671
            1356-1475           AL935159.11        34901-35020
            1476-1662           AL935159.11        39911-40097
            1663-1777           AL935159.11        40752-40866
            1778-2601           AL935159.11        42166-42989
FEATURES             Location/Qualifiers
     source          1..2601
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2"
     gene            1..2601
                     /gene="Slc43a3"
                     /gene_synonym="Eeg1; SEEEG-1"
                     /note="solute carrier family 43, member 3"
                     /db_xref="GeneID:58207"
                     /db_xref="MGI:MGI:1931054"
     exon            1..204
                     /gene="Slc43a3"
                     /gene_synonym="Eeg1; SEEEG-1"
                     /inference="alignment:Splign:2.1.0"
     exon            205..551
                     /gene="Slc43a3"
                     /gene_synonym="Eeg1; SEEEG-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             368..1876
                     /gene="Slc43a3"
                     /gene_synonym="Eeg1; SEEEG-1"
                     /note="embryonic epithelial gene 1; selectively expressed
                     in embryonic epithelia protein-1; embryonic epithelia gene
                     1 protein"
                     /codon_start=1
                     /product="equilibrative nucleobase transporter 1"
                     /protein_id="NP_067373.2"
                     /db_xref="CCDS:CCDS38164.1"
                     /db_xref="GeneID:58207"
                     /db_xref="MGI:MGI:1931054"
                     /translation="MASKGLPLYLATLLTGLLECIGFAGVLFGWTSLLFVFKAENYFS
                     EPCEQDCLLQSNVTGPSDLKAQDEKFSLIFTLASFMNNFMTFPTGYIFDRFKTTVARL
                     IAIFFYTCATIIIAFTSANTAMLLFLAMPMLAVGGILFLITNLQIGNLFGKHRSTIIT
                     LYNGAFDSSSAVFLVIKLLYEQGISLRSSFIFMSVCSVWHIARTFLLMPKGHIPYPLP
                     PNYSYGLCSRFGASKKENKAAEHETKELRSKECLPPKEENSGPEQQQQQEQQQQQQQQ
                     QEQHEQHSFRRCALSRRFILHVVWLSIIQLWHYLFIGTLNSLLTKLSGGDKVEVSAYT
                     NAFAITQFFGVLCAPWNGLLMDRLKQKYQKAAKRTGSSSEAVALCSMVPSLALTSLLS
                     LGFALCASIPVMQLQYATFILQVVSRSFLYGCNAAFLTLAFPSEHFGKLFGLVMALSA
                     IVSLLQFPLFKVSPESNAVYVSMGLAIFLTLVHPFLVYRECRAEKTKSSVDA"
     exon            552..681
                     /gene="Slc43a3"
                     /gene_synonym="Eeg1; SEEEG-1"
                     /inference="alignment:Splign:2.1.0"
     exon            682..728
                     /gene="Slc43a3"
                     /gene_synonym="Eeg1; SEEEG-1"
                     /inference="alignment:Splign:2.1.0"
     exon            729..805
                     /gene="Slc43a3"
                     /gene_synonym="Eeg1; SEEEG-1"
                     /inference="alignment:Splign:2.1.0"
     exon            806..898
                     /gene="Slc43a3"
                     /gene_synonym="Eeg1; SEEEG-1"
                     /inference="alignment:Splign:2.1.0"
     exon            899..1038
                     /gene="Slc43a3"
                     /gene_synonym="Eeg1; SEEEG-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1039..1136
                     /gene="Slc43a3"
                     /gene_synonym="Eeg1; SEEEG-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1137..1355
                     /gene="Slc43a3"
                     /gene_synonym="Eeg1; SEEEG-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1356..1475
                     /gene="Slc43a3"
                     /gene_synonym="Eeg1; SEEEG-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1476..1662
                     /gene="Slc43a3"
                     /gene_synonym="Eeg1; SEEEG-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1663..1777
                     /gene="Slc43a3"
                     /gene_synonym="Eeg1; SEEEG-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1778..2601
                     /gene="Slc43a3"
                     /gene_synonym="Eeg1; SEEEG-1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 taggactgga aggatactgg ccgggtctgg ccgagctggg ctgggtctgg ctgagcagag
       61 cagagccgag ccgggcaaag ctcgacaggg aggctctggg cggagggtag tggaaggcgg
      121 tagcctggtg gcggcgaggc tgcggcgaca gagatccggg agagagttgc tgccggctgg
      181 agcgcgacct cttgcctggt ggaagctcca tggttattcc atggcgtttc ttgctcaacc
      241 cagagacagc tggaacaaga gggctcattg aagtcgagag cttgccaaag gaatttccca
      301 cacatcacta ccagtggtcc tctctgaagc tcaggacagg atttgtggac tcacttcacc
      361 tcagaccatg gcaagcaagg gcttgcccct ttacttggcc accttgttga ctggactctt
      421 ggaatgcatc ggttttgctg gtgtcctctt tggctggact tcactgttgt ttgtgttcaa
      481 agcagaaaac tacttttcag agccctgtga acaggactgc ttgctccaga gcaatgtaac
      541 agggccttct gatttaaaag cgcaggatga gaagttctca ctcatcttta ccctggcatc
      601 cttcatgaat aacttcatga cctttcccac tggctacatc tttgaccgct tcaagactac
      661 tgtggcccgc ctgatagcca tatttttcta cacctgcgcc acgatcatca ttgccttcac
      721 ctctgcaaac actgccatgc tgctcttcct agccatgccc atgctcgcag tgggaggaat
      781 cctgttcctt atcaccaacc tacagattgg gaacctcttt gggaaacacc gttcaaccat
      841 catcaccctc tacaatggag catttgactc ctcctcagca gtgttcctcg tcattaagct
      901 gctttacgag cagggcatca gcctcaggtc ttccttcatc ttcatgtctg tctgcagtgt
      961 ctggcacatt gcgcgtactt tccttctgat gcccaaggga catatcccct acccactgcc
     1021 tcccaactac agctatggct tgtgctccag gtttggtgct agcaagaaag agaataaagc
     1081 agctgaacac gaaaccaagg agctgcggtc aaaggaatgt ctgccaccca aggaagagaa
     1141 ctctggacca gaacagcagc agcagcagga gcagcagcag cagcagcagc agcagcagga
     1201 gcaacacgag caacactctt ttcgacgctg cgcgctctct cgtcgattca tcttgcacgt
     1261 ggtgtggctg tctatcatac agttgtggca ttacctcttc attggtactc tcaactctct
     1321 actcaccaag ttatccggtg gggacaaagt ggaagtcagt gcctacacaa atgcctttgc
     1381 catcacccag ttctttggcg tgctgtgtgc cccctggaat ggcttactca tggaccgcct
     1441 taaacagaag tatcagaagg cagccaaaag gacaggttcc tcgtctgagg ctgtggctct
     1501 ctgctccatg gtgccttcac tggctctgac gtctctgctg tccctgggct ttgccctgtg
     1561 tgcctccatt cctgtcatgc agctacagta cgccaccttc atcctgcaag tggtcagccg
     1621 ctccttcctg tatggatgca atgctgcctt cctcacgctg gcatttccct cagagcattt
     1681 tggaaagctc tttgggctgg tgatggcctt gtcagctatt gtgtctctgc tacagttccc
     1741 cctgttcaaa gtctcccctg agagcaacgc tgtgtatgta tcgatggggc ttgccatttt
     1801 cctgacattg gtccatccct tcctggtgta ccgtgagtgc cgtgctgaga agacaaaatc
     1861 gtctgtggat gcctagtcca ctctctagcc tcgatgatgc cttttctgtt cattactcga
     1921 ctttgatgat ccagtatcta caaagactgc ctccccagga gaactgtaat cggcagtcat
     1981 agtttttctt aaaccactgc caccacaaga aacaaaccaa caaaaaccaa aaaaacagaa
     2041 acaaaaaaca aggcactcaa atgtcaccta ggacttttga tttccaagat gagtggaaat
     2101 ttcagtggcc aagcagcctt cacaccaacc caaagcaaag atttagatga gtttttagtt
     2161 actccctgca cagggccaca gcagagctca ttgcaaggga cagggagata tgtcacagag
     2221 tcatgctacc ccaaaggact tgggatccaa ctgactggct agccagaaag attttggaca
     2281 acactttgta tcttgcctgt gagcaatgtc tcctcttcag gaaaagggct attcattgac
     2341 ttagggcagc ttttatatat aattagcttg gggttggaga gatggcttaa ctcttaagag
     2401 cactggctgc tcttccagag gacctggttt gatttttagc acccacatag tggctcacaa
     2461 actgtaactg cagtccctcc atggatactg catgcttgtg cacagacata tatgcagaca
     2521 aaacatccat acacattaaa caaatataat ttctctaggg aatactttta tacaataata
     2581 aagcctctat gtttaaggca a
//
