LOCUS       NM_027868               2272 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus solute carrier family 41, member 3 (Slc41a3),
            transcript variant 1, mRNA.
ACCESSION   NM_027868 XM_132686
VERSION     NM_027868.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2272)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2272)
  AUTHORS   Ilenwabor,B.P., Franken,G.A.C., Sponder,G., Bos,C., Racay,P.,
            Kolisek,M., Hoenderop,J.G.J. and de Baaij,J.H.F.
  TITLE     SLC41A1 knockout mice display normal magnesium homeostasis
  JOURNAL   Am J Physiol Renal Physiol 323 (5), F553-F563 (2022)
   PUBMED   36049064
REFERENCE   3  (bases 1 to 2272)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2272)
  AUTHORS   de Baaij,J.H., Arjona,F.J., van den Brand,M., Lavrijsen,M.,
            Lameris,A.L., Bindels,R.J. and Hoenderop,J.G.
  TITLE     Identification of SLC41A3 as a novel player in magnesium
            homeostasis
  JOURNAL   Sci Rep 6, 28565 (2016)
   PUBMED   27349617
  REMARK    GeneRIF: SLC41A3 was established as a new factor for Mg(2+)
            handling.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2272)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
REFERENCE   6  (bases 1 to 2272)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB872292.1, BY108317.1, CN699671.1, AK003140.1 and AW492407.1.
            
            On Nov 29, 2005 this sequence version replaced NM_027868.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC011108.1, SRR9219381.104321.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-51                BB872292.1         1-51
            52-397              BY108317.1         8-353
            398-612             CN699671.1         312-526
            613-2245            AK003140.1         581-2213
            2246-2272           AW492407.1         1-27                c
FEATURES             Location/Qualifiers
     source          1..2272
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 40.16 cM"
     gene            1..2272
                     /gene="Slc41a3"
                     /gene_synonym="1010001P06Rik; SLC41A1-L2"
                     /note="solute carrier family 41, member 3"
                     /db_xref="GeneID:71699"
                     /db_xref="MGI:MGI:1918949"
     exon            1..129
                     /gene="Slc41a3"
                     /gene_synonym="1010001P06Rik; SLC41A1-L2"
                     /inference="alignment:Splign:2.1.0"
     exon            130..432
                     /gene="Slc41a3"
                     /gene_synonym="1010001P06Rik; SLC41A1-L2"
                     /inference="alignment:Splign:2.1.0"
     CDS             160..1626
                     /gene="Slc41a3"
                     /gene_synonym="1010001P06Rik; SLC41A1-L2"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="solute carrier family 41 member 3 isoform 1"
                     /protein_id="NP_082144.2"
                     /db_xref="CCDS:CCDS20362.1"
                     /db_xref="GeneID:71699"
                     /db_xref="MGI:MGI:1918949"
                     /translation="MEGTEARQRRLEGCGRLKELGPLPSHDAGRLPKASEEGHLAVSE
                     SQLVDAKSLEAPPGRETSLIIGFQVVIPFLLAGMGLSWAGLLLNYFQHWPVFKDVKDL
                     MTLVPPLVGLKGNLEMTLASRLSTSANTGQIDDRQERYKIISSNLAVVQVQATVVGLL
                     AAVASLMLGTVSHEEFDWSKVALLCTSSVITAFLAALALGILMICIVIGARKFGVNPD
                     NIATPIAASLGDLITLSILALMSSFFYSHKDTWYLTPLVCVGFLALTPLWLFIAKQNP
                     PIMKILKYGWFPIILAMIISSFGGLILSKTISKHEFKGMAVLTPVMCGVGGNLVAIQT
                     SRISTFLHMWSTPGVLPVQMKRFWPNPCFIFCSSEINSVSARVLLFLVVPGHLIFFYL
                     ICLVEGQSVTNSKIFILLYLVAGVVQVVILLYLAEVTVRLTWHQALDPDNHCIPYLTG
                     LGDLLGTSLLALCFFLDWLLRGRANLQELVSELVSVPP"
     exon            433..540
                     /gene="Slc41a3"
                     /gene_synonym="1010001P06Rik; SLC41A1-L2"
                     /inference="alignment:Splign:2.1.0"
     exon            541..612
                     /gene="Slc41a3"
                     /gene_synonym="1010001P06Rik; SLC41A1-L2"
                     /inference="alignment:Splign:2.1.0"
     exon            613..757
                     /gene="Slc41a3"
                     /gene_synonym="1010001P06Rik; SLC41A1-L2"
                     /inference="alignment:Splign:2.1.0"
     exon            758..904
                     /gene="Slc41a3"
                     /gene_synonym="1010001P06Rik; SLC41A1-L2"
                     /inference="alignment:Splign:2.1.0"
     exon            905..1049
                     /gene="Slc41a3"
                     /gene_synonym="1010001P06Rik; SLC41A1-L2"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..1129
                     /gene="Slc41a3"
                     /gene_synonym="1010001P06Rik; SLC41A1-L2"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1264
                     /gene="Slc41a3"
                     /gene_synonym="1010001P06Rik; SLC41A1-L2"
                     /inference="alignment:Splign:2.1.0"
     exon            1265..1413
                     /gene="Slc41a3"
                     /gene_synonym="1010001P06Rik; SLC41A1-L2"
                     /inference="alignment:Splign:2.1.0"
     exon            1414..2257
                     /gene="Slc41a3"
                     /gene_synonym="1010001P06Rik; SLC41A1-L2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2236..2241
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc41a3"
                     /gene_synonym="1010001P06Rik; SLC41A1-L2"
                     /note="hexamer: AATAAA"
     polyA_site      2257
                     /gene="Slc41a3"
                     /gene_synonym="1010001P06Rik; SLC41A1-L2"
                     /note="major polyA site"
ORIGIN      
        1 tgtctggacg cctaggcagg gcggggctgg cccgcctgct gcccttctcg cttcctcccg
       61 ccgcaggcct ccacagtgtc cagcgcgcgc ctggccgcct cgctttcgcc gccggccggg
      121 agaggaccgg tcagggctgc tgggctcagc cgtgtgctga tggaagggac agaagcccga
      181 cagaggaggc tggaaggctg tggaaggctg aaggagctgg ggccattgcc cagccacgat
      241 gcaggaagac tcccaaaggc ttctgaagaa ggacacctgg cggtctctga gagccaactg
      301 gtggatgcca aatcactgga ggccccgcct ggcagggaga cgtccctgat cattggcttt
      361 caggtggtaa tacccttcct gcttgcaggc atgggactgt cctgggctgg cttgcttctg
      421 aactatttcc agcactggcc agtgttcaaa gatgttaaag acctgatgac gttggtgcca
      481 cccctcgtcg gtctgaaggg aaacctggaa atgacgctgg cgtctcggct ctccacgtct
      541 gccaacactg ggcaaatcga tgaccgccag gagaggtaca aaatcatcag cagcaacctc
      601 gctgtggttc aggtgcaggc cactgttgtg gggctcctgg ctgcagtggc ctccctgatg
      661 ctgggcacag tgtcccacga ggagttcgat tggtccaagg tggccttgct gtgcacgagc
      721 agcgtcatca ccgccttcct tgctgccttg gccctaggaa ttctaatgat ctgcatagtg
      781 attggtgctc ggaagtttgg ggtcaaccct gataacatcg ccacacccat tgcagccagc
      841 ctgggcgacc tcatcaccct gtccatcctg gccctcatga gcagtttctt ctacagccac
      901 aaagacacat ggtatctgac gcctctggtc tgtgtcggct tcttggctct cacccctctg
      961 tggctcttca ttgccaagca gaacccgccc atcatgaaga tcctgaagta tgggtggttt
     1021 cccatcatcc tggctatgat catcagcagt ttcggaggtc tcatcctgag caaaaccatt
     1081 tcgaaacatg aatttaaagg catggctgtc ctgactccag tcatgtgtgg tgttggtggc
     1141 aacctggtgg ccattcagac tagccgcatc tccacctttc tgcatatgtg gagcacaccc
     1201 ggggtcctcc ctgtccagat gaaaagattc tggcctaacc cctgcttcat tttctgctct
     1261 tcagaaatca attctgtgtc agcacgagtc ctgctctttc tggtggtccc aggacacctg
     1321 attttcttct acctcatctg cctggtggaa ggccagtcag tgacaaacag caagatcttc
     1381 atattgctgt acctggtggc aggcgtggtc caggtggtca tcctgctgta cctggcagaa
     1441 gtgacagttc ggctgacatg gcaccaagcc ctggatcctg acaaccactg catcccctac
     1501 ctcacggggc tgggggacct gctgggcact agcctgctgg cactgtgctt cttcctggac
     1561 tggttactga ggggcagagc taatcttcag gagctggtct cagagctggt ttctgtgcct
     1621 ccctgactga gcctaccacc cgcaggtctc catgaaactt tccctcatgt cctcagtggt
     1681 ctggcaagcc gttcacccct gctgacaggc ttcaagctgc taaacacctt cgagggcagt
     1741 ggcctcatca gtctgccagg gagacaagta cacaccttga ctctcaagtt ggcagcccag
     1801 cctgaagtag agctctgaca ttaggagctc tgcttgcaag tgtgtgagta tgtatgcctg
     1861 gactctgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtagggca
     1921 ggctgttcta acctgaagat gctgaggaag gagcctattg gtgcaaccta ggttggtgat
     1981 ccattgggtg gatcaggacg gaactctgtg tccccaggtc tcaggagtgc catccccggg
     2041 ctcagctcca gttccctggg ctcatgctac tagtgctctg ggcccagtga ccatgcacct
     2101 tcaccccagg caggccctgt gtacccctcc tctatactcc agcatttaat cttgtggctg
     2161 ctttcttttt atttcccact ttctctgttt tataacagaa ccttctgtat aggttctggc
     2221 aatcaagaga tgtataataa aacatagctt acgtgaaaaa aaaaaaaaaa aa
//
