LOCUS       NM_177388               4386 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus solute carrier family 41, member 2 (Slc41a2), mRNA.
ACCESSION   NM_177388
VERSION     NM_177388.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4386)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4386)
  AUTHORS   Goytain,A. and Quamme,G.A.
  TITLE     Functional characterization of the mouse [corrected] solute
            carrier, SLC41A2
  JOURNAL   Biochem Biophys Res Commun 330 (3), 701-705 (2005)
   PUBMED   15809054
  REMARK    GeneRIF: SLC41A2 is a Mg2+ transporter that might be involved in
            magnesium homeostasis in epithelial cells
            Erratum:[Biochem Biophys Res Commun. 2007 May 11;356(3):822]
REFERENCE   3  (bases 1 to 4386)
  AUTHORS   Willnow,T., Antignac,C., Brandli,A., Christensen,E., Cox,R.,
            Davidson,D., Davies,J., Devuyst,O., Eichele,G., Hastie,N.,
            Verroust,P., Schedl,A. and Meij,I.
  TITLE     The European renal genome project: an integrated approach towards
            understanding the genetics of kidney development and disease
  JOURNAL   Organogenesis 2 (2), 42-47 (2005)
   PUBMED   19521566
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK038549.1.
            
            On Apr 6, 2007 this sequence version replaced NM_177388.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK038549.1, SRR9219383.34587.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4386              AK038549.1         2-4387
FEATURES             Location/Qualifiers
     source          1..4386
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 41.03 cM"
     gene            1..4386
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /note="solute carrier family 41, member 2"
                     /db_xref="GeneID:338365"
                     /db_xref="MGI:MGI:2442940"
     exon            1..58
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /inference="alignment:Splign:2.1.0"
     exon            59..793
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /inference="alignment:Splign:2.1.0"
     CDS             239..1960
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /codon_start=1
                     /product="solute carrier family 41 member 2"
                     /protein_id="NP_796362.1"
                     /db_xref="CCDS:CCDS24075.1"
                     /db_xref="GeneID:338365"
                     /db_xref="MGI:MGI:2442940"
                     /translation="MTHSKGRPVTYKTSASPESGGGFVDWTLNLNTIQSDKFLNLLLS
                     MVPVIYQKNQEDRHKKVNGIWQDGLSGAAQTFSKRSEPHLDYHEFSEQAFHSSSSGHT
                     PASCSPKYDDYAGYNYCDGREASETTAMLQDEDLSSEGDDVIVETSQRIPKESSGVMA
                     LQILVPFLLAGFGTVSAGMVLDIVQHWEVFKNVTEVFILVPALLGLKGNLEMTLASRL
                     STAVNVGKMDSPIEKWNLIIGNLALKQVQATVVGFLAAVAAIILGWIPEGKYYLSHSI
                     LLCSSSVATAFIASLLQGIIMVGVIVGSKKTGINPDNVATPIAASFGDLITLAILAWI
                     SQGLYSCLETYYYISPLVCAFFLALTPIWIIIAAKHPATRTVLHSGWEPVITAMVISS
                     IGGLILDTTVSDPNLVGIVVYTPVINGIGGNLVAIQASRISTYLHLHSIPGELPEEPK
                     GCSYPFRTFFGSGVNNKSAQVLLLFVIPGHLIFLYTIHLMKSGHTSLTVVFVVVYLFA
                     AVLQVFTLLWIADWMVHRFWRKGKDPDSFSIPYLTALGDLLGTALLALSFHFLWLIGD
                     RDGDVGD"
     exon            794..901
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /inference="alignment:Splign:2.1.0"
     exon            902..973
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1118
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1265
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /inference="alignment:Splign:2.1.0"
     exon            1266..1413
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /inference="alignment:Splign:2.1.0"
     exon            1414..1493
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /inference="alignment:Splign:2.1.0"
     exon            1494..1625
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /inference="alignment:Splign:2.1.0"
     exon            1626..1774
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /inference="alignment:Splign:2.1.0"
     exon            1775..4386
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2134
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /note="major polyA site"
     regulatory      2163..2168
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /note="hexamer: AATAAA"
     regulatory      2167..2172
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /note="hexamer: AATAAT"
     polyA_site      2186
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /note="major polyA site"
     polyA_site      2193
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
     regulatory      2725..2730
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /note="hexamer: ATTAAA"
     polyA_site      2746
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
     regulatory      3473..3478
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
                     /note="hexamer: TATAAA"
     polyA_site      3495
                     /gene="Slc41a2"
                     /gene_synonym="A230035L05Rik; SLC41A1-L1"
ORIGIN      
        1 ttccgctcag caaggaacgc gagctggacc cccgacgagg cccggggctg acggagcgat
       61 tgaattcctc tcttaaacgt ctggattttt ttctttttct tttttttttt taaccagtgg
      121 aaactttttc tacctagtgg tcaatggctt aatttgaaca agcgttgctg tggctttggt
      181 tccgctgtgc ttttggaagc ttgggtctga aggatacagg tctttttgtg atgacaatat
      241 gacccacagt aaaggaagac ctgtcactta caagacaagt gccagtccgg agagtggagg
      301 aggttttgta gattggactt taaatttaaa tacaattcaa tctgacaagt ttttgaactt
      361 acttttaagc atggtgccag tcatttacca gaaaaatcag gaagacaggc ataaaaaagt
      421 aaatggcatc tggcaggacg ggctgtcggg tgcagcacag accttcagca agagatcaga
      481 gccacatctg gactaccacg agttctcaga gcaagccttc cacagcagca gcagtgggca
      541 cactccagcc agctgcagcc ccaagtacga tgactatgct ggctataact actgtgacgg
      601 gagggaggct tcggaaacca ccgccatgtt acaggacgaa gatctgtcca gcgagggcga
      661 tgatgttatt gtggaaacaa gccagaggat tccaaaggag tccagtgggg tcatggctct
      721 gcagatattg gtgccattct tgctggctgg gtttggaacg gtttctgctg gcatggtttt
      781 ggacatagtg cagcactggg aggtgttcaa aaatgtgaca gaagtcttca ttttggtccc
      841 cgcgcttctt ggtcttaaag gaaacttgga aatgacgctg gcttctcgat tatctactgc
      901 agtaaatgtt gggaagatgg actcacccat tgagaagtgg aatctaatca ttggcaactt
      961 ggctttaaag caggttcagg ccacagtggt tggcttttta gcagctgtgg cagccatcat
     1021 actgggctgg attccagaag ggaagtatta cctcagccat tccatacttc tgtgctccag
     1081 cagtgtggca acggccttca tcgcatctct actgcaggga ataataatgg ttggtgttat
     1141 cgttggctcc aagaagactg gcataaaccc tgacaacgtg gccacaccca ttgctgctag
     1201 ttttggtgat ctgataactc tcgccatatt agcttggata agtcagggtt tgtactcctg
     1261 tcttgagaca tattattaca tttccccatt agtgtgtgcc tttttcttgg ctctgactcc
     1321 tatctggatt ataatagctg ccaagcaccc agctaccagg acagtgctcc actcaggctg
     1381 ggagcctgtc ataacagcca tggttataag cagcatcggg ggccttattc tggacacaac
     1441 tgtatctgac ccaaacttgg ttgggattgt tgtttacacg ccagttatca acgggatcgg
     1501 tggcaatttg gtggccattc aggctagcag gatttctacc tacctccatt tacatagcat
     1561 ccccggagaa ctacctgagg agcccaaagg ctgttcctac ccatttagga cattttttgg
     1621 ttcaggagtg aacaataagt ctgcccaggt tctcctgctc ttcgtgatcc cgggccactt
     1681 gatcttcctc tacacaattc acctgatgaa gagtggccac acctctctga ctgtagtctt
     1741 tgttgttgtg tacctgtttg ctgctgtgct gcaggtgttc accctgctgt ggatcgccga
     1801 ctggatggtc catcgcttct ggagaaaagg aaaggaccca gacagtttct ccatcccgta
     1861 cctcacggcg ctgggcgatc tgcttgggac tgctctgctg gccttaagct tccattttct
     1921 ctggctcatt ggagaccgag atggagacgt tggagactaa tgggacctag aagctgtcgt
     1981 ggggtcacac aggggaagga tacaggcagc cattgctgcc cctccccaaa gctcttcatc
     2041 tgtcctgtaa cttatgccag ggtagtctgc agttcaccct gactccgtaa atggccttaa
     2101 tgtacttttt aaggaatttg tgccgaaacc acaatgaatg gtatttgtgc tgctttttgt
     2161 agaataaata atttgacaca gacatagata caagctcaca ttctaaagtt aattaggaaa
     2221 gaatttagga tgtttacaat gagttaattt tgaaaccaca gacctagcag aaatagactt
     2281 tattattaag ttataatgca cagttagagg caagggagtg ttagccttgt cttacagctg
     2341 tgtcacacta cagagtgcca tgactgatgt gacgggggcc agctgaacgt ccctaagtgt
     2401 tcattaggcc ttcctccctg ggagctaagg ttaccagtta cttaactcac aatacccctc
     2461 ccactgaaca taacaaccag ctcactttta cccatatcta aaactgccct gcgccaacgt
     2521 tcatctctgc tcagcgagtt ctcaacagct aaccctttag tagatttgtt tattctttcg
     2581 tggagacagg gcttgctatg ttgtccctgt agtcttttca cttgcagtcc cccttgcttt
     2641 ggctcccttc tcctggtgct aaaagcactg agctgtctcg ctcatcctgt gttgaaaaag
     2701 gttgatccga tttagaaaac cgtgattaaa gcagaaggtg tgctgagctg tgtttgtggg
     2761 cccaagatgg agtgcgtgcg tgtgcgcatg tgtgagggac aggcccgaga aagacagaga
     2821 caaagtagtt tctttctcaa aaatgagtac catttaatat aatgcagacc taggatctgg
     2881 gacgtgcagg tggtcctgtt gccctttaag gcgccctacc tgttggatgt cccaagttgg
     2941 cggcttacct cagcatctac tgcatcaggg ctccatctcc tgggaccgcc tcatggccgt
     3001 ggctgcgctc ctcagatgtc tttctgaacg taagcaccta acccctggct attcagtagt
     3061 aagcacttta aaattgcccg gcaatcgttc aaggccgtta aatatttaat aatttaaact
     3121 gctgagggca tggactccgc atgacgttga ttgtcatggc gaggttgtgc tggtgaagaa
     3181 ctagcaggta gcttgtaaat atactgagga agtttctcac taaatcttta tggaggctgt
     3241 ggtttagagt tgtatatttt tgcttatttt taaacttcgt tcaattctcc tgccttataa
     3301 tcaaacattt aaggcataga acggaatgaa ttacaggatc tctcctttgg agagttagtg
     3361 tcacggagtg accattctga caaaataagc ataaagttta agttgatgaa taagtattta
     3421 gttgcaaaga ttattttatt taaaaattaa tgaatactac ctttcatttt attataaaag
     3481 catttgtgaa tttgggtttt gcatttggct gtacattctt ttggtttttg ttttgttttg
     3541 ttttgttttg ttttgttttg ttttgttttt gagacagagt cttgcccagg cttaaacttc
     3601 agctccacct gccttagcct gttgggattc attttcttta actcacaaag agtatgcaga
     3661 gtaagcccca gtgttagcct ggttggcagt gttaggcata ttcctaagca cgggaagatg
     3721 tgtgagctac cgtgtgtggt gctgacagcc tcgcctggca ggtgggttga atggagactc
     3781 ctgtctgtgt tttatcaagg gggaaataca gaggagtgac atttgtaaga tttcacagct
     3841 atgcagggaa cagactcttc acatgtgtgt cccaccccca gatgtgcaaa gggtctacct
     3901 agttagctga gaaaaagccc aatcaagtgt tactagtctt ttagattggc agcagggaaa
     3961 cctccaccta gtgtggacca actgtgaact ctccccgttc ctaaggtcag agagactgta
     4021 tatgaacatt taccttataa aatatttttt attttataat gaagaccttt agactaaaga
     4081 acaatgcctc gattcttcag gcctccaaga gccagccctc ttcctagatc tgctgtgtca
     4141 ggcagtagag gctttatcgg aacagcaaaa tatctaagac acatgtagtg ggcagaaata
     4201 gactcggact gaatgcattg tgaagggata tgcactgtta attacagatc tttgaaagtc
     4261 tctgtgtaag tatgtaagtt ttatttatcc ataaaaaggt aaatgaataa tatttttata
     4321 ccacacaaac cctgctttcc aaaactggtt tcccactaac ttaccaggca cattatacac
     4381 acagcc
//
