LOCUS       NM_027216               2721 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus solute carrier family 39 (metal ion transporter),
            member 11 (Slc39a11), transcript variant 2, mRNA.
ACCESSION   NM_027216 XM_979808
VERSION     NM_027216.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2721)
  AUTHORS   Martin,A.B., Aydemir,T.B., Guthrie,G.J., Samuelson,D.A., Chang,S.M.
            and Cousins,R.J.
  TITLE     Gastric and colonic zinc transporter ZIP11 (Slc39a11) in mice
            responds to dietary zinc and exhibits nuclear localization
  JOURNAL   J Nutr 143 (12), 1882-1888 (2013)
   PUBMED   24089422
REFERENCE   2  (bases 1 to 2721)
  AUTHORS   Yu,Y., Wu,A., Zhang,Z., Yan,G., Zhang,F., Zhang,L., Shen,X., Hu,R.,
            Zhang,Y., Zhang,K. and Wang,F.
  TITLE     Characterization of the GufA subfamily member SLC39A11/Zip11 as a
            zinc transporter
  JOURNAL   J Nutr Biochem 24 (10), 1697-1708 (2013)
   PUBMED   23643525
  REMARK    GeneRIF: data suggest that Zip11 has unique protein sequence and
            structure features, it functions as a cellular zinc transporter,
            and its expression is at least partially regulated by zinc via
            hMTF-1 binding to metal response element sequences of Zip11
            promoter.
REFERENCE   3  (bases 1 to 2721)
  AUTHORS   Kelleher,S.L., Velasquez,V., Croxford,T.P., McCormick,N.H.,
            Lopez,V. and MacDavid,J.
  TITLE     Mapping the zinc-transporting system in mammary cells: molecular
            analysis reveals a phenotype-dependent zinc-transporting network
            during lactation
  JOURNAL   J Cell Physiol 227 (4), 1761-1770 (2012)
   PUBMED   21702047
REFERENCE   4  (bases 1 to 2721)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY299357.1 and AK036999.1.
            
            On Oct 27, 2009 this sequence version replaced NM_027216.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK036999.1, AK170673.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-371               BY299357.1         2-372
            372-2721            AK036999.1         319-2668
FEATURES             Location/Qualifiers
     source          1..2721
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 78.74 cM"
     gene            1..2721
                     /gene="Slc39a11"
                     /gene_synonym="1810074D23Rik; ZIP-11"
                     /note="solute carrier family 39 (metal ion transporter),
                     member 11"
                     /db_xref="GeneID:69806"
                     /db_xref="MGI:MGI:1917056"
     exon            1..140
                     /gene="Slc39a11"
                     /gene_synonym="1810074D23Rik; ZIP-11"
                     /inference="alignment:Splign:2.1.0"
     exon            141..259
                     /gene="Slc39a11"
                     /gene_synonym="1810074D23Rik; ZIP-11"
                     /inference="alignment:Splign:2.1.0"
     CDS             152..1159
                     /gene="Slc39a11"
                     /gene_synonym="1810074D23Rik; ZIP-11"
                     /note="isoform 2 is encoded by transcript variant 2; zinc
                     transporter ZIP11; zrt- and Irt-like protein 11; solute
                     carrier family 39 member 11"
                     /codon_start=1
                     /product="zinc transporter ZIP11 isoform 2"
                     /protein_id="NP_081492.4"
                     /db_xref="CCDS:CCDS36363.1"
                     /db_xref="GeneID:69806"
                     /db_xref="MGI:MGI:1917056"
                     /translation="MLQGYSSVVQALLGTFFTWAMTAAGAALVFIFSSGQRRILDGSL
                     GFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMPHL
                     GATEDPQTALALNLDPALMKKSDPRDPTSLLFPESELSIRIDKRENGEVYQRKKVAAT
                     DLAEGVAPSGSMHGSSGQPGGSSWRRIALLILAITIHNIPEGLAVGVGFGAVEKTASA
                     TFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWKAFWYGQLSGMVEPLAGVFGAFA
                     VVLAEPILPYALAFAAGAMVYVVMDDIIPEAQISGNGKLASWASILGFVVMMSLDVGL
                     G"
     exon            260..298
                     /gene="Slc39a11"
                     /gene_synonym="1810074D23Rik; ZIP-11"
                     /inference="alignment:Splign:2.1.0"
     exon            299..457
                     /gene="Slc39a11"
                     /gene_synonym="1810074D23Rik; ZIP-11"
                     /inference="alignment:Splign:2.1.0"
     exon            458..581
                     /gene="Slc39a11"
                     /gene_synonym="1810074D23Rik; ZIP-11"
                     /inference="alignment:Splign:2.1.0"
     exon            582..752
                     /gene="Slc39a11"
                     /gene_synonym="1810074D23Rik; ZIP-11"
                     /inference="alignment:Splign:2.1.0"
     exon            753..822
                     /gene="Slc39a11"
                     /gene_synonym="1810074D23Rik; ZIP-11"
                     /inference="alignment:Splign:2.1.0"
     exon            823..921
                     /gene="Slc39a11"
                     /gene_synonym="1810074D23Rik; ZIP-11"
                     /inference="alignment:Splign:2.1.0"
     exon            922..1080
                     /gene="Slc39a11"
                     /gene_synonym="1810074D23Rik; ZIP-11"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..2721
                     /gene="Slc39a11"
                     /gene_synonym="1810074D23Rik; ZIP-11"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggttgcgaag gggcggggcc cggcggtgga gggccacgtg tgctggagtg aagcaggaag
       61 tgaccgcgag agtggagccg ggcgagcgag tggcatcggg ggctgatgga agtggagagg
      121 gggctggaga gggcacccta cagtatccag catgctccaa ggttacagct ccgtggtcca
      181 ggccttgctg gggaccttct tcacctgggc aatgacagca gccggggcag ctctcgtgtt
      241 catattctcc agcgggcaga ggcggatctt agacggaagc ctgggctttg ccgcaggggt
      301 catgttagcg gcttcctact ggtcgctgct tgcaccagcg gtggagatgg cgacatcctc
      361 ggggggcttc ggagcctttg ccttcttccc agtggctgtt ggcttcaccc tgggggccgc
      421 ctttgtctac ctggctgacc tcctgatgcc tcacctgggt gctacagaag acccccagac
      481 agccctggcg ctgaacttgg accctgcatt gatgaagaag tctgatccca gggaccccac
      541 ttcgctgctc ttcccggaga gtgaactttc catccggata gacaagcgtg agaatggcga
      601 ggtataccag aggaagaagg tggcagctac tgacctcgca gagggcgtgg ccccctcagg
      661 atcgatgcac gggagctcag ggcagcctgg ggggagcagc tggaggagga ttgctttgct
      721 catcctggcc atcaccatac acaacattcc agagggtctt gctgttggcg taggatttgg
      781 agcagtagaa aagactgcat ctgccacctt cgagagtgcc aggaatctgg ccattggaat
      841 tgggatccag aatttcccag agggcctggc tgtcagcctt cctctgcgtg gagcaggctt
      901 ctctacctgg aaagctttct ggtatggaca gctgagcggc atggtggagc ccttggctgg
      961 ggtctttgga gcatttgcgg tggtactggc tgagcccatc ctgccctatg cactggcctt
     1021 tgctgctggt gccatggtct acgtggtcat ggatgacatc atccccgagg cccagatcag
     1081 tggcaacggg aagctggcat cctgggcctc catcctggga tttgtggtga tgatgtccct
     1141 tgatgtgggc ctcggctagc tctgacaaac cgtgggactc cgtgaaggaa agcaccaggc
     1201 ttctgtagga ccatgagcct ctcattacaa cccggttcct ttctcccctc cgtctcctta
     1261 ccccaaatca gctctgatca cattttgact cttcgttttg ctttggaggg agacgctggt
     1321 tttctttgta atctcaaggt gtcatagaac tgtagatttg tgtgtggacc actgagtgga
     1381 aggcatcttt cttcagtggg attgtcgagg ctaaccccta cttgtcccac ctccagtctc
     1441 cctcactaga ctcaacttca acacctcagg gtcacctcca gaagtcagct cctgggctag
     1501 aagtcctgag catgttggcc tgaggttttg gagcaggctg ccagggcccc ttgtgctcct
     1561 tctccataga ccctctgtcc acctagaatt ctgggacaga agccacatga acccagaagc
     1621 ctgctttctg aggctgagcc agctcaaaca gggtctgctt cctctaggga ggcgtgcgcg
     1681 ggaggcatgc gcgggaggca tgcgcgggag gacccacaca ccaagggaag gaaggcagct
     1741 tgtctctctc ctttgtccta agacaaggat tgacattgct gatgttagag caatatggaa
     1801 atgagggtga ccctgaacac gcagcgctct ttgaagagta ctgtaagcag gttttaagct
     1861 gagcttcccc ctgtcccccg ggctctttgt agatgacaag agcaggcact ttgtagtggc
     1921 tcccagatct cctagctatt aatcttgatg tgtttacagc ctttgttttt ctgagagact
     1981 tgtggatacc agcaaatggc aaatagtcaa tcccctcatt gactaacagg gttacttcag
     2041 tcaactctag ggaatgatat tcagggccta acaaggctcc ttctctgctg gccacttgga
     2101 aacttattac ccagagcccc tcagcttcag cgggctttgt gggaatctgg ccagcgggct
     2161 tctaatggga aaggaagggg gctggggtaa gaagaggtat ttttacattc cctttcttaa
     2221 aaaaacttaa acttctgaga tgactggacc tagactacat gctaacctac cccatcatac
     2281 atgtagctcc gccatcagct ctcccaatgc atctgagccc tccatggctg agaagcatgt
     2341 gggactcaga gaacagactc taccccagag cctggcattt gggtactgac tgggctatca
     2401 gtatcttgcc tctgtgttta catgttccgt ctctccaagg atggatattg tagtctgtga
     2461 atgctcaaga ccccagaggc caacctcggc ggggtgtgtc cattcttctg acgcactggt
     2521 gatcaaaggc ttcaatcaca cattgaagcc atattcagag atttgattat ctggtgaggt
     2581 tagctggtgt ggtgattggc acgtgcgtat atatttttat tcttaggtct ccatgtgtag
     2641 ttctgttgct gcaaatcatg ctttctgccg gataagacct cgtgactgtg attaatgtca
     2701 ataaagggaa ttttgttgcg c
//
