LOCUS       NM_172758               3282 bp    mRNA    linear   ROD 06-AUG-2023
DEFINITION  Mus musculus solute carrier family 38, member 7 (Slc38a7), mRNA.
ACCESSION   NM_172758
VERSION     NM_172758.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3282)
  AUTHORS   Verdon Q, Boonen M, Ribes C, Jadot M, Gasnier B and Sagne C.
  TITLE     SNAT7 is the primary lysosomal glutamine exporter required for
            extracellular protein-dependent growth of cancer cells
  JOURNAL   Proc Natl Acad Sci U S A 114 (18), E3602-E3611 (2017)
   PUBMED   28416685
REFERENCE   2  (bases 1 to 3282)
  AUTHORS   Hagglund MG, Sreedharan S, Nilsson VC, Shaik JH, Almkvist IM,
            Backlin S, Wrange O and Fredriksson R.
  TITLE     Identification of SLC38A7 (SNAT7) protein as a glutamine
            transporter expressed in neurons
  JOURNAL   J Biol Chem 286 (23), 20500-20511 (2011)
   PUBMED   21511949
  REMARK    GeneRIF: The preferred substrate and axonal localization of SLC38A7
            close to the synaptic cleft indicates that SLC38A7 could have an
            important function for the reuptake and recycling of glutamate.
REFERENCE   3  (bases 1 to 3282)
  AUTHORS   Taniwaki T, Haruna K, Nakamura H, Sekimoto T, Oike Y, Imaizumi T,
            Saito F, Muta M, Soejima Y, Utoh A, Nakagata N, Araki M, Yamamura K
            and Araki K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   4  (bases 1 to 3282)
  AUTHORS   Araki K, Imaizumi T, Sekimoto T, Yoshinobu K, Yoshimuta J, Akizuki
            M, Miura K, Araki M and Yamamura K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC127300.3.
            
            [WARNING] On Dec 26, 2023 this sequence was replaced by
            NM_172758.5.
            
            On Oct 19, 2007 this sequence version replaced NM_172758.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK052548.1, ERR3363658.3373570.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                AC127300.3         45164-45183
            21-126              AC127300.3         45748-45853
            127-514             AC127300.3         49887-50274
            515-713             AC127300.3         52324-52522
            714-858             AC127300.3         52712-52856
            859-957             AC127300.3         53669-53767
            958-1015            AC127300.3         54494-54551
            1016-1130           AC127300.3         54781-54895
            1131-1278           AC127300.3         56332-56479
            1279-1478           AC127300.3         56934-57133
            1479-1533           AC127300.3         58187-58241
            1534-3282           AC127300.3         60984-62732
FEATURES             Location/Qualifiers
     source          1..3282
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 47.67 cM"
     gene            1..3282
                     /gene="Slc38a7"
                     /gene_synonym="D430050E18"
                     /note="solute carrier family 38, member 7"
                     /db_xref="GeneID:234595"
                     /db_xref="MGI:MGI:2679005"
     exon            1..20
                     /gene="Slc38a7"
                     /gene_synonym="D430050E18"
                     /inference="alignment:Splign:2.1.0"
     exon            21..126
                     /gene="Slc38a7"
                     /gene_synonym="D430050E18"
                     /inference="alignment:Splign:2.1.0"
     exon            127..514
                     /gene="Slc38a7"
                     /gene_synonym="D430050E18"
                     /inference="alignment:Splign:2.1.0"
     CDS             245..1636
                     /gene="Slc38a7"
                     /gene_synonym="D430050E18"
                     /note="amino acid transporter; putative sodium-coupled
                     neutral amino acid transporter 7"
                     /codon_start=1
                     /product="sodium-coupled neutral amino acid transporter 7"
                     /protein_id="NP_766346.1"
                     /db_xref="CCDS:CCDS22567.1"
                     /db_xref="GeneID:234595"
                     /db_xref="MGI:MGI:2679005"
                     /translation="MAQVSINSDYSEWASSTDAGERARLLQSPCVDVVPKSEGEASPG
                     DPDSGTTSTLGAVFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVI
                     LAYCSQASNERTYQEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAV
                     MSKEPDGASGSPWYTDRKFTISLTAFLFILPLSIPKEIGFQKYASFLSVVGTWYVTAI
                     IIIKYIWPDKEMRPGDILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMRQPEVKT
                     WGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLRSYPSEDVAVAVARAFIILSVL
                     TSYPILHFCGRAVVEGLWLRYKGMPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDI
                     GKVISVIGGLAACFIFIFPGLCLIQAKLSEMEEVKPASWWALVSYGVLLVTLGAFIFG
                     QTTANAIFVDLLA"
     exon            515..713
                     /gene="Slc38a7"
                     /gene_synonym="D430050E18"
                     /inference="alignment:Splign:2.1.0"
     exon            714..858
                     /gene="Slc38a7"
                     /gene_synonym="D430050E18"
                     /inference="alignment:Splign:2.1.0"
     exon            859..957
                     /gene="Slc38a7"
                     /gene_synonym="D430050E18"
                     /inference="alignment:Splign:2.1.0"
     exon            958..1015
                     /gene="Slc38a7"
                     /gene_synonym="D430050E18"
                     /inference="alignment:Splign:2.1.0"
     exon            1016..1130
                     /gene="Slc38a7"
                     /gene_synonym="D430050E18"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1278
                     /gene="Slc38a7"
                     /gene_synonym="D430050E18"
                     /inference="alignment:Splign:2.1.0"
     exon            1279..1478
                     /gene="Slc38a7"
                     /gene_synonym="D430050E18"
                     /inference="alignment:Splign:2.1.0"
     exon            1479..1533
                     /gene="Slc38a7"
                     /gene_synonym="D430050E18"
                     /inference="alignment:Splign:2.1.0"
     exon            1534..3282
                     /gene="Slc38a7"
                     /gene_synonym="D430050E18"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tacaaggtat gtgaaaggag atttttagat aaagccttga gaagaacttg aggccaaaag
       61 gggaggtgag ggggctctga ccccatacct ttaggcagag gaaacagccc tcttctagat
      121 tagcaggttg acaagagttc cccgagatta gaagccctga aggagcgggc atcctcccag
      181 ctaccccagg aatgtggtcg tgaggcagag cccgcagctt tcagaagaag agtagtcttg
      241 ggccatggcc caggtcagca tcaacagtga ctacagcgag tgggcttcca gcactgatgc
      301 tggggagcgg gcccgtttgc tccaaagtcc ctgtgtggat gtggtaccta agagtgaggg
      361 ggaggcgtct cctggagatc cagacagcgg caccacttcg acgcttggag ccgtcttcat
      421 cgtcgtcaat gcctgcctcg gtgcgggtct gctcaacttc ccagcagcct tcagcaccgc
      481 tgggggcgtg gcagctggca tcgccctgca gatgggcatg ctggttttta tcatcagtgg
      541 gctggtcatt ctggcctact gctctcaagc cagcaatgag aggacctacc aggaggtggt
      601 gtgggccgtg tgtggcaagc tgacaggtgt gctgtgtgag gtagccattg cggtctatac
      661 cttcggaacc tgcatcgcct tcctcatcat tattggggac cagcaggaca agattatagc
      721 tgtgatgtcg aaggagccgg atggggccag cggcagcccc tggtacacag accgcaagtt
      781 caccatcagt cttaccgcct tcctcttcat cctgcccctg tccatcccca aggagattgg
      841 cttccagaaa tatgccagct tcctgagcgt cgtgggcacc tggtacgtca ccgccattat
      901 aatcatcaaa tacatctggc cagataaaga gatgcgcccg ggggacatct tgactagacc
      961 agcgtcctgg atggctgtgt tcaacgccat gcccaccatc tgctttggat ttcagtgtca
     1021 tgtgagtagt gtacccgtct tcaacagcat gcggcagccc gaagtaaaga cctggggcgg
     1081 agtggtgacg gctgccatgg tcatagctct ggctgtctac atgggcacag gcatctgtgg
     1141 cttcctaacc tttggagctg ctgtggaccc cgacgtgctc cggtcctacc cctcagagga
     1201 cgtggctgtg gccgttgccc gagccttcat catcctgagt gtgctcacct cctatccaat
     1261 cttgcacttc tgtgggcggg ctgtggtgga aggcctgtgg ctgcgctaca aggggatgcc
     1321 cgtggaggag gatgtgggcc gggagcgccg gcgccgggtc ctgcagacgc tggtgtggtt
     1381 cctgctgacc ttgctactgg cgctctttat ccctgacatt ggcaaggtca tctcggtcat
     1441 cggaggcctg gcagcctgct tcatcttcat cttcccaggg ctgtgcctca ttcaagccaa
     1501 actatcagag atggaggagg tcaaacctgc cagctggtgg gcactggtca gttacggagt
     1561 ccttctggtc acattgggag ccttcatctt cggccagacc acagccaatg ccatttttgt
     1621 ggatctcttg gcctgaactc tgcttcccca gaaacatgag gaccgagcat cgctcagagc
     1681 tgtggagctg cccaagtccc acgtcccatt ccagccagtg agatgacatg tggactcctt
     1741 tccccatgga cagtcatgag acaatcagcc gcagatctgt ggacggctcc cgcccagctg
     1801 ccttgcatcc tgaccccacg ttctcatgga tggaggtccc atatcacagg agcttcttcc
     1861 cctttgctcg gatctccact tcaagccttt gggacttgag gatggagagg gtcagtgggt
     1921 ctcagaagag agagtctatt ctgacttccc tctggaaaaa gaacaacaac aaaaaaatgc
     1981 atctgcagag ggctggcgtc ctccgcggag cgtggcagga ctgtgctcag tacctcgggg
     2041 ttttgtgcct gcccatgtct ctcagaagcc agtgacaact tctcctggga cctggcaact
     2101 tccaaaggag ctgctgacat catataaatg tccaaattcc cctcttggtc ccctatgagt
     2161 ctctggtagc ttcgcaagtc tttgggctcc ctactgtgac tttgtccaaa caaagtggtc
     2221 catgttgggt ttgcttctgc tgtgttcccg gacatcacca agtctaatgt ttacaaagcc
     2281 agcctggctt cggagctagg ggctgccatg ccacggtgct ctgagcactc ctccgttagc
     2341 tctttatgca tgggcagagg gtctgttgtc tttttcagat tccagataag cccgtctttt
     2401 cagaggttta gggtaggatc ttttagacca tccttccagg cagggatgct caaggtccgg
     2461 gtgaagttct gcctcactcc tccaagcctg tcctctctct tctcccgcta aacccagccc
     2521 cagaacccag aaggagttag actggggacc ctggatgttt cccttcctgt ttccatcttt
     2581 acccatcccc acatggccat ccctctcccc caaccctatc tcttctcttt cttcatttgt
     2641 gggttttgtt atttggtggg gggggggggg ggtgtggcgc cagaccctgt cacaccagct
     2701 tgcctggctc cacacgtctg tcaagcctgg cctccatgcc tgggaatcct gctgaatcat
     2761 acccacccca ggtgaggtca gcatagacac ttctctcttg actgccttag cttcgaacct
     2821 acccctgctc acttttgtaa gtcccaagta cagaattggt ctttataaat ctattctgtc
     2881 taaaacactt atcctaggag tgaaagggac ccttcccagc agactacccc ctgcccccaa
     2941 cacaggtcag tcctgttgag gcaggaggct tagcatccag acttgctgaa ttgttgttct
     3001 cccatccatc cctggtactt ctggtcccgc tacactgttt tcccctagcc ccccaacccc
     3061 cataagcctc caagtgctgc ctttcacagt gaccaatcac agagctgggc atggcttaga
     3121 gacgtgctag ctgggacagt tggctagaac caggcttcag cttgtcctca ggaccccctt
     3181 cctccgtccc ctttgccctc tgtatccagt ttcttgctgg ttcttttcta ctcaagcaca
     3241 cttggagacg tgaggatgat taataaaggg acttacactg ct
//
