LOCUS       NM_008063               1908 bp    mRNA    linear   ROD 15-FEB-2024
DEFINITION  Mus musculus solute carrier family 37 (glucose-6-phosphate
            transporter), member 4 (Slc37a4), transcript variant 2, mRNA.
ACCESSION   NM_008063
VERSION     NM_008063.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1908)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1908)
  AUTHORS   Raggi,F., Pissavino,A.L., Resaz,R., Segalerba,D., Puglisi,A.,
            Vanni,C., Antonini,F., Del Zotto,G., Gamberucci,A., Marcolongo,P.,
            Bosco,M.C., Grillo,F., Mastracci,L. and Eva,A.
  TITLE     Development and characterization of an inducible mouse model for
            glycogen storage disease type Ib
  JOURNAL   J Inherit Metab Dis 41 (6), 1015-1025 (2018)
   PUBMED   29967951
REFERENCE   3  (bases 1 to 1908)
  AUTHORS   Kwon,J.H., Lee,Y.M., Cho,J.H., Kim,G.Y., Anduaga,J., Starost,M.F.,
            Mansfield,B.C. and Chou,J.Y.
  TITLE     Liver-directed gene therapy for murine glycogen storage disease
            type Ib
  JOURNAL   Hum Mol Genet 26 (22), 4395-4405 (2017)
   PUBMED   28973635
REFERENCE   4  (bases 1 to 1908)
  AUTHORS   Kim,G.Y., Kwon,J.H., Cho,J.H., Zhang,L., Mansfield,B.C. and
            Chou,J.Y.
  TITLE     Downregulation of pathways implicated in liver inflammation and
            tumorigenesis of glycogen storage disease type Ia mice receiving
            gene therapy
  JOURNAL   Hum Mol Genet 26 (10), 1890-1899 (2017)
   PUBMED   28334808
REFERENCE   5  (bases 1 to 1908)
  AUTHORS   Kim,G.Y., Lee,Y.M., Kwon,J.H., Jun,H.S. and Chou,J.
  TITLE     Glycogen storage disease type Ib neutrophils exhibit impaired cell
            adhesion and migration
  JOURNAL   Biochem Biophys Res Commun 482 (4), 569-574 (2017)
   PUBMED   27864142
REFERENCE   6  (bases 1 to 1908)
  AUTHORS   Kameya,S., Hawes,N.L., Chang,B., Heckenlively,J.R., Naggert,J.K.
            and Nishina,P.M.
  TITLE     Mfrp, a gene encoding a frizzled related protein, is mutated in the
            mouse retinal degeneration 6
  JOURNAL   Hum Mol Genet 11 (16), 1879-1886 (2002)
   PUBMED   12140190
REFERENCE   7  (bases 1 to 1908)
  AUTHORS   Reese,J., Das,S.K., Paria,B.C., Lim,H., Song,H., Matsumoto,H.,
            Knudtson,K.L., DuBois,R.N. and Dey,S.K.
  TITLE     Global gene expression analysis to identify molecular markers of
            uterine receptivity and embryo implantation
  JOURNAL   J Biol Chem 276 (47), 44137-44145 (2001)
   PUBMED   11551965
REFERENCE   8  (bases 1 to 1908)
  AUTHORS   Hiraiwa,H., Pan,C.J., Lin,B., Akiyama,T.E., Gonzalez,F.J. and
            Chou,J.Y.
  TITLE     A molecular link between the common phenotypes of type 1 glycogen
            storage disease and HNF1alpha-null mice
  JOURNAL   J Biol Chem 276 (11), 7963-7967 (2001)
   PUBMED   11121425
REFERENCE   9  (bases 1 to 1908)
  AUTHORS   Gerin,I., Veiga-da-Cunha,M., Noel,G. and Van Schaftingen,E.
  TITLE     Structure of the gene mutated in glycogen storage disease type Ib
  JOURNAL   Gene 227 (2), 189-195 (1999)
   PUBMED   10023055
REFERENCE   10 (bases 1 to 1908)
  AUTHORS   Lin,B., Annabi,B., Hiraiwa,H., Pan,C.J. and Chou,J.Y.
  TITLE     Cloning and characterization of cDNAs encoding a candidate glycogen
            storage disease type 1b protein in rodents
  JOURNAL   J Biol Chem 273 (48), 31656-31660 (1998)
   PUBMED   9822626
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122428.4.
            
            On Mar 11, 2020 this sequence version replaced NM_008063.2.
            
            Transcript Variant: This variant (2) differs in the 5' UTR and
            lacks an alternate in-frame exon compared to variant 4. The
            resulting isoform (b) has the same N- and C-termini but is shorter
            compared to isoform a. Variants 1-3 and 7 all encode the same
            isoform (b).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC075655.1, AK003620.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-268               AC122428.4         86154-86421         c
            269-501             AC122428.4         85294-85526         c
            502-745             AC122428.4         84737-84980         c
            746-904             AC122428.4         84128-84286         c
            905-990             AC122428.4         83843-83928         c
            991-1104            AC122428.4         83241-83354         c
            1105-1243           AC122428.4         82564-82702         c
            1244-1908           AC122428.4         81809-82473         c
FEATURES             Location/Qualifiers
     source          1..1908
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 24.84 cM"
     gene            1..1908
                     /gene="Slc37a4"
                     /gene_synonym="100043178; G6PT; G6pt1; GSD-1b; mG6PT"
                     /note="solute carrier family 37 (glucose-6-phosphate
                     transporter), member 4"
                     /db_xref="GeneID:14385"
                     /db_xref="MGI:MGI:1316650"
     exon            1..268
                     /gene="Slc37a4"
                     /gene_synonym="100043178; G6PT; G6pt1; GSD-1b; mG6PT"
                     /inference="alignment:Splign:2.1.0"
     CDS             121..1410
                     /gene="Slc37a4"
                     /gene_synonym="100043178; G6PT; G6pt1; GSD-1b; mG6PT"
                     /note="isoform b is encoded by transcript variant 2;
                     solute carrier family 37 (glycerol-6-phosphate
                     transporter), member 4; glucose 6-phosphate transporter;
                     glucose-6-phosphatase, transport protein 1"
                     /codon_start=1
                     /product="glucose-6-phosphate exchanger SLC37A4 isoform b"
                     /protein_id="NP_032089.2"
                     /db_xref="CCDS:CCDS23108.1"
                     /db_xref="GeneID:14385"
                     /db_xref="MGI:MGI:1316650"
                     /translation="MAAQGYGYYRTVIFAAMFGGYSLYYFNRKTFSFVMPSLVDEIAL
                     DKDDLGLITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNVVFSWSSTVSA
                     FAALWFLNGLAQGLGWPPCGKILRKWFEPSQFGTWWAVLSTSMNLAGSLGPILATILA
                     QSYSWRSTLALSGALCVVVSFFCLLLIHNEPADVGLRNLDPAPSKGKKGSSKEESTLQ
                     DLLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQERGQSALVGSSYISALEVGGLVG
                     SIAAGYLSDRAMAKAGLSLYGNPRHGLLLLMMAGMAASMFLFRVTVTSDSPKIWILVL
                     GAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYS
                     WSTAFWVAEVVCGASTVVFFLLRNIRTKMGRVSKKGE"
     exon            269..501
                     /gene="Slc37a4"
                     /gene_synonym="100043178; G6PT; G6pt1; GSD-1b; mG6PT"
                     /inference="alignment:Splign:2.1.0"
     exon            502..745
                     /gene="Slc37a4"
                     /gene_synonym="100043178; G6PT; G6pt1; GSD-1b; mG6PT"
                     /inference="alignment:Splign:2.1.0"
     exon            746..904
                     /gene="Slc37a4"
                     /gene_synonym="100043178; G6PT; G6pt1; GSD-1b; mG6PT"
                     /inference="alignment:Splign:2.1.0"
     exon            905..990
                     /gene="Slc37a4"
                     /gene_synonym="100043178; G6PT; G6pt1; GSD-1b; mG6PT"
                     /inference="alignment:Splign:2.1.0"
     exon            991..1104
                     /gene="Slc37a4"
                     /gene_synonym="100043178; G6PT; G6pt1; GSD-1b; mG6PT"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1243
                     /gene="Slc37a4"
                     /gene_synonym="100043178; G6PT; G6pt1; GSD-1b; mG6PT"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1908
                     /gene="Slc37a4"
                     /gene_synonym="100043178; G6PT; G6pt1; GSD-1b; mG6PT"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcacagaaaa acacagctca gcagatccag gcactaaaga gagctagctg caagcaggag
       61 cagtcaagaa tctgtggtca gaagtactgg agtgggccag cagggccagc tttttctacc
      121 atggcagccc aaggctacgg ctactatcgc actgtcatat ttgcggccat gtttggaggc
      181 tacagcctgt actatttcaa ccgcaaaacc ttctcctttg tcatgccctc cttggtggat
      241 gagatcgctc tggacaagga cgatttgggg ctcatcacaa gcagccagtc ggcagcctac
      301 gccatcagca agtttgtgag cggggttctg tcagatcaga tgagcgcccg ctggctcttc
      361 tcctctgggc tgctcctggt tggtctggtc aacgtagtct tctcatggag ctccacagtg
      421 tcagcctttg ctgctctttg gtttcttaat ggtctggcac aggggctggg ctggcccccc
      481 tgtgggaaga tcctgaggaa gtggtttgag ccatcccagt ttggcacttg gtgggctgtg
      541 ttgtcaacca gcatgaacct ggctggaagt ttgggaccta tcttggcaac gatcctcgcc
      601 cagagctaca gctggcgcag cacactggcc ctgtctgggg cactgtgtgt ggttgtctcc
      661 ttcttctgtc tgctgcttat ccacaatgaa cctgctgatg ttggactccg aaatctggac
      721 cctgccccct ccaagggcaa aaagggctca tcaaaggagg agagcaccct acaggatctg
      781 ctgctgtccc cctatctctg ggtgctgtcc actggctacc tcgtggtctt cggagtaaag
      841 acttgctgta cagactgggg ccagttcttc cttatccagg agcgagggca gtccgccctt
      901 gtgggtagct cctacatcag tgccctcgag gtcggaggcc ttgtaggaag cattgcagct
      961 ggttacctgt cagacagggc catggcgaag gcagggctgt ctctgtatgg gaaccctcgt
     1021 cacggcctat tgctactcat gatggctggg atggcagcat ccatgttcct cttccgagta
     1081 acggtgacca gtgactcacc caagatctgg atcctggttt taggagccgt gtttggtttc
     1141 tcttcttatg gtcccattgc cttgtttgga gtcatagcca atgagagtgc acctcccaac
     1201 ttgtgtggaa cctctcatgc tattgtggga cttatggcca atgtgggtgg atttctggct
     1261 ggcttaccct tcagcaccat tgccaagcac tatagctgga gcacagcctt ctgggtggca
     1321 gaagtggttt gtggagccag cacagttgtc ttcttcttgc ttcgaaatat ccgcaccaag
     1381 atgggccgag tatccaagaa gggagagtga atcgagtcct cgctatggag catccccaac
     1441 tgcagcctta ctggcaggac acggaaagga gagcggctgc tctggctaac acagaacctt
     1501 tacgtttctg tgtctccact gtctctctga acctccatgg tgctgcaagt taccagtggc
     1561 taatgaggtc ccgactccca tcccatgctc tatttaaaat gatgatgttt ggttctagac
     1621 tccatcagct tctgtttcta ccttctggca gacaggcaac tcctgaattc agagtgtctc
     1681 ctataccctt cttcttctcc taggtcctga tctcctagtg agtattaatg gcctgtggtt
     1741 tctgctgtac cccaaggctt cttggcaggg ggcaaaattg ttgccaatac ctcagtccct
     1801 aagggaggag aggagtccac cactctcatg aataccctgg gacaaaaggg aagaatatag
     1861 agggcaaacc gacttgtata gatcaataaa gctagatttg atactaaa
//
