LOCUS       NM_172258               1768 bp    mRNA    linear   ROD 31-MAY-2024
DEFINITION  Mus musculus solute carrier family 36 (proton/amino acid
            symporter), member 3 (Slc36a3), transcript variant 1, mRNA.
ACCESSION   NM_172258
VERSION     NM_172258.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1768)
  AUTHORS   Lu,Y., Oura,S., Matsumura,T., Oji,A., Sakurai,N., Fujihara,Y.,
            Shimada,K., Miyata,H., Tobita,T., Noda,T., Castaneda,J.M.,
            Kiyozumi,D., Zhang,Q., Larasati,T., Young,S.A.M., Kodani,M.,
            Huddleston,C.A., Robertson,M.J., Coarfa,C., Isotani,A.,
            Aitken,R.J., Okabe,M., Matzuk,M.M., Garcia,T.X. and Ikawa,M.
  TITLE     CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched
            genes dispensable for male fertility in micedagger
  JOURNAL   Biol Reprod 101 (2), 501-511 (2019)
   PUBMED   31201419
REFERENCE   2  (bases 1 to 1768)
  AUTHORS   Bermingham,J.R. Jr. and Pennington,J.
  TITLE     Organization and expression of the SLC36 cluster of amino acid
            transporter genes
  JOURNAL   Mamm Genome 15 (2), 114-125 (2004)
   PUBMED   15058382
REFERENCE   3  (bases 1 to 1768)
  AUTHORS   Boll,M., Foltz,M., Rubio-Aliaga,I. and Daniel,H.
  TITLE     A cluster of proton/amino acid transporter genes in the human and
            mouse genomes
  JOURNAL   Genomics 82 (1), 47-56 (2003)
   PUBMED   12809675
  REMARK    GeneRIF: PAT3 was isolated and identified, but its function is not
            yet known.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL713870.26, AF453745.1 and AL772357.9.
            
            On May 19, 2018 this sequence version replaced NM_172258.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY211261.1, AF453745.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 AL713870.26        27674-27675         c
            3-224               AF453745.1         1-222
            225-226             AL713870.26        27319-27320         c
            227-391             AF453745.1         225-389
            392-392             AL713870.26        27153-27153         c
            393-1760            AF453745.1         391-1758
            1761-1768           AL772357.9         38044-38051         c
FEATURES             Location/Qualifiers
     source          1..1768
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 32.13 cM"
     gene            1..1768
                     /gene="Slc36a3"
                     /gene_synonym="PAT3; TRAMD2; tramdorin2"
                     /note="solute carrier family 36 (proton/amino acid
                     symporter), member 3"
                     /db_xref="GeneID:215332"
                     /db_xref="MGI:MGI:2665001"
     exon            1..137
                     /gene="Slc36a3"
                     /gene_synonym="PAT3; TRAMD2; tramdorin2"
                     /inference="alignment:Splign:2.1.0"
     exon            138..408
                     /gene="Slc36a3"
                     /gene_synonym="PAT3; TRAMD2; tramdorin2"
                     /inference="alignment:Splign:2.1.0"
     CDS             257..1690
                     /gene="Slc36a3"
                     /gene_synonym="PAT3; TRAMD2; tramdorin2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     proton/amino acid transporter 3; tramdorin 2;
                     proton-coupled amino acid transporter 3; solute carrier
                     family 36 member 3"
                     /codon_start=1
                     /product="proton-coupled amino acid transporter 3 isoform
                     1"
                     /protein_id="NP_758462.2"
                     /db_xref="CCDS:CCDS24708.1"
                     /db_xref="GeneID:215332"
                     /db_xref="MGI:MGI:2665001"
                     /translation="MGNVPLLREVGKCQRNMFGRSTASSKGSSNSRSSSSTSPKKGPR
                     READALMFIQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDILL
                     NCACHLTQRLQRSFVNYEETTMYSLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFCSV
                     YFMFLADNLQQIMEEAHFTSNVCQPRQSLVMTSILDTRFYMLTILPFLILLVLIQNPQ
                     VLSIFSTLATITTLSSLALIFEYLIQTPHHSNLPLVANWKTFLLFFGTAIFTFEGVGM
                     VLPLKSQMKSPQQFPAVLYLGMSFVIFLYICLGTLGYMKFGTDTQASITLNLPICWLY
                     QSVKLMYSVGIFFTYALQFHVPAEIIVPYVVSRVSENWALFVDLTVRTALVCLTCFSA
                     VLIPRLDLVISLVGSVSSSALAIIIPPLLEIATFYSENISCATIVKDIMISILGLLGC
                     VLGTYQALYEMTQQTHFYMANSTRVHI"
     exon            409..499
                     /gene="Slc36a3"
                     /gene_synonym="PAT3; TRAMD2; tramdorin2"
                     /inference="alignment:Splign:2.1.0"
     exon            500..588
                     /gene="Slc36a3"
                     /gene_synonym="PAT3; TRAMD2; tramdorin2"
                     /inference="alignment:Splign:2.1.0"
     exon            589..684
                     /gene="Slc36a3"
                     /gene_synonym="PAT3; TRAMD2; tramdorin2"
                     /inference="alignment:Splign:2.1.0"
     exon            685..769
                     /gene="Slc36a3"
                     /gene_synonym="PAT3; TRAMD2; tramdorin2"
                     /inference="alignment:Splign:2.1.0"
     exon            770..988
                     /gene="Slc36a3"
                     /gene_synonym="PAT3; TRAMD2; tramdorin2"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1084
                     /gene="Slc36a3"
                     /gene_synonym="PAT3; TRAMD2; tramdorin2"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1251
                     /gene="Slc36a3"
                     /gene_synonym="PAT3; TRAMD2; tramdorin2"
                     /inference="alignment:Splign:2.1.0"
     exon            1252..1421
                     /gene="Slc36a3"
                     /gene_synonym="PAT3; TRAMD2; tramdorin2"
                     /inference="alignment:Splign:2.1.0"
     exon            1422..1768
                     /gene="Slc36a3"
                     /gene_synonym="PAT3; TRAMD2; tramdorin2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1745..1750
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc36a3"
                     /gene_synonym="PAT3; TRAMD2; tramdorin2"
                     /note="hexamer: ATTATA"
     polyA_site      1764
                     /gene="Slc36a3"
                     /gene_synonym="PAT3; TRAMD2; tramdorin2"
                     /note="major polyA site"
ORIGIN      
        1 agaggcaaca aaccctgagc ctgagcccac agctaggcac cagaacttcc ggtctaatga
       61 taccttcctc ctccttggtc agtgttcccc gtggaccaca gcatcaagga ctgatctggg
      121 agaggctgaa agtctgtggc caggcatacc caggagtcag gagccagaac ctgagacctg
      181 ctgtatggct tctcctgatg aaagcccact gagagcctgc ggcagctgag tgctatacct
      241 ctgctgcctg tccatcatgg ggaatgtgcc gctgcttaga gaagttggca agtgtcagcg
      301 gaatatgttc ggtcggtcta cagcctcctc aaaaggcagc agcaacagca gaagcagcag
      361 cagtacctcc ccaaagaagg gccctcgcag ggaagctgat gcgctaatgt ttatacagat
      421 ctttatccac ctgttgaaaa gcaacattgg cacaggcttc ctgggactgc ccctggctgt
      481 gaaaaatgct ggattgttgg tggggcctgt cagcctcttg gccatcgggg cgctcacagt
      541 gcactgtatg gatatcctgc tgaactgtgc ctgccatctc actcagagac tgcagaggag
      601 ttttgtgaac tatgaagaga ccacaatgta cagcctggaa acgtgtccaa gtccttggct
      661 gaggacgcac tcagtgtggg gcaggtacgt tgtgagcttc ctgctgatcg tcactcagct
      721 gggcttctgc agcgtgtact tcatgtttct ggcggacaac ttacaacaga tcatggaaga
      781 agcccacttc acctccaacg tctgccagcc gaggcagagc ctggtgatga cctccatcct
      841 ggacactcgc ttctatatgc tcaccatcct gcccttcctc atcctgctgg tgctcatcca
      901 gaacccacag gtgttgtcca tcttctctac cttggccacc atcaccaccc tgagcagcct
      961 ggctctgatc ttcgagtatc tcatccagac cccacaccac agcaacctgc ccctggttgc
     1021 aaactggaag actttcttgc tgttctttgg cacggctatc ttcacctttg aaggcgtggg
     1081 gatggttctg cctctcaaaa gccagatgaa gagcccgcag cagttccccg ctgtgctgta
     1141 tctggggatg tcctttgtca tcttcctcta catctgcctg gggactctgg gctacatgaa
     1201 gtttgggaca gacactcagg ccagcatcac cctcaacttg cccatttgct ggctgtacca
     1261 gtcagtcaag ctgatgtact ctgtgggcat cttcttcacc tatgccctcc agttccacgt
     1321 cccagctgag atcatcgtcc cctatgtcgt ctcaagagtg tctgagaact gggctctgtt
     1381 cgtagacctg actgtccgca cagccttggt ctgcctgacc tgtttctcag ccgtcctcat
     1441 cccccgcctg gacctggtca tctccctggt gggctctgtg agcagtagcg ccctggccat
     1501 catcatcccg ccgctgctgg agattgccac attttactct gagaacataa gctgtgccac
     1561 cattgtcaag gacatcatga tcagcatcct gggcctctta gggtgtgtac ttgggacata
     1621 ccaagccctg tacgagatga cccagcagac ccacttttac atggccaact ctacaagggt
     1681 ccacatataa ttacctattt ttatttgaat agctcttcct ttctccaccc tctgttggat
     1741 ttgcattata tgtgttcatc aaaatcca
//
