LOCUS       NM_177186               6333 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus solute carrier family 35, member E2 (Slc35e2), mRNA.
ACCESSION   NM_177186
VERSION     NM_177186.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6333)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6333)
  AUTHORS   Li,Y., Feng,R., Yu,X., Li,L., Liu,Y., Zhang,R., Chen,X., Zhao,Y.
            and Liu,Z.
  TITLE     SLC35E2 promoter mutation as a prognostic marker of esophageal
            squamous cell carcinoma
  JOURNAL   Life Sci 296, 120447 (2022)
   PUBMED   35247439
  REMARK    GeneRIF: SLC35E2 promoter mutation as a prognostic marker of
            esophageal squamous cell carcinoma.
            Erratum:[Life Sci. 2022 Jun 1;298:120493. doi:
            10.1016/j.lfs.2022.120493.. PMID: 35346501]
REFERENCE   3  (bases 1 to 6333)
  AUTHORS   Cui,W., Dai,X., Marcho,C., Han,Z., Zhang,K., Tremblay,K.D. and
            Mager,J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6333)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 6333)
  AUTHORS   Gineste,C., De Winter,J.M., Kohl,C., Witt,C.C., Giannesini,B.,
            Brohm,K., Le Fur,Y., Gretz,N., Vilmen,C., Pecchi,E., Jubeau,M.,
            Cozzone,P.J., Stienen,G.J., Granzier,H., Labeit,S.,
            Ottenheijm,C.A., Bendahan,D. and Gondin,J.
  TITLE     In vivo and in vitro investigations of heterozygous nebulin
            knock-out mice disclose a mild skeletal muscle phenotype
  JOURNAL   Neuromuscul Disord 23 (4), 357-369 (2013)
   PUBMED   23375831
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC058728.1 and AK142259.1.
            
            On Apr 11, 2007 this sequence version replaced NM_177186.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.2767447.1,
                                           SRR7652917.121384.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3972              BC058728.1         1-3972
            3973-5198           AK142259.1         1088-2313
            5199-5884           AK142259.1         2315-3000
            5885-6333           BC058728.1         4946-5394
FEATURES             Location/Qualifiers
     source          1..6333
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 86.62 cM"
     gene            1..6333
                     /gene="Slc35e2"
                     /gene_synonym="A530082C11Rik; Slc35e2a"
                     /note="solute carrier family 35, member E2"
                     /db_xref="GeneID:320541"
                     /db_xref="MGI:MGI:2444240"
     exon            1..323
                     /gene="Slc35e2"
                     /gene_synonym="A530082C11Rik; Slc35e2a"
                     /inference="alignment:Splign:2.1.0"
     exon            324..804
                     /gene="Slc35e2"
                     /gene_synonym="A530082C11Rik; Slc35e2a"
                     /inference="alignment:Splign:2.1.0"
     CDS             483..1700
                     /gene="Slc35e2"
                     /gene_synonym="A530082C11Rik; Slc35e2a"
                     /codon_start=1
                     /product="solute carrier family 35 member E2A"
                     /protein_id="NP_796160.1"
                     /db_xref="CCDS:CCDS38995.1"
                     /db_xref="GeneID:320541"
                     /db_xref="MGI:MGI:2444240"
                     /translation="MSAAAKSQVPEEAAPGCEEEPKGKTLLTWGSLFGHRSEKIVFTK
                     GDGSPEESLLTVTITETTVIESDLGVWSSRALIYLTLWFFFSFCTLFLNKYILSLLEG
                     EPSMLGAVQMLSTTLIGCVKIFVPCCLYQHKTRLSYPPNFIMTMLFVGLMRFATVVLG
                     LVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGLLVNLSLIPVMGGLALCTATEI
                     SFNILGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAPELQFYTSAAAVALLIPAWTF
                     FMDIPVIGRSGKSFSYSQDIVLLLLTDGALFHLQSVTAYALMGKISPVTFSVASTVKH
                     ALSIWLSIIVFGNKITSLSAIGTILVTLGVLLYNKARQYQQETMQSLVTATSRNPEDD
                     TEPLVPQDSRQHH"
     exon            805..940
                     /gene="Slc35e2"
                     /gene_synonym="A530082C11Rik; Slc35e2a"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1068
                     /gene="Slc35e2"
                     /gene_synonym="A530082C11Rik; Slc35e2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1189
                     /gene="Slc35e2"
                     /gene_synonym="A530082C11Rik; Slc35e2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..1243
                     /gene="Slc35e2"
                     /gene_synonym="A530082C11Rik; Slc35e2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1316
                     /gene="Slc35e2"
                     /gene_synonym="A530082C11Rik; Slc35e2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1317..1462
                     /gene="Slc35e2"
                     /gene_synonym="A530082C11Rik; Slc35e2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1463..6291
                     /gene="Slc35e2"
                     /gene_synonym="A530082C11Rik; Slc35e2a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6268..6273
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc35e2"
                     /gene_synonym="A530082C11Rik; Slc35e2a"
                     /note="hexamer: AATAAA"
     polyA_site      6291
                     /gene="Slc35e2"
                     /gene_synonym="A530082C11Rik; Slc35e2a"
                     /note="major polyA site"
ORIGIN      
        1 gggggttcct cgcacgttcg ccactgagcg cttctcgtct tgtgactttc tggtcagatt
       61 ttaggatcct tgaaatcaag cccctgggtc tgacctagag ggcggcacct tcgcggcctc
      121 agaggattgg ctccttcacc ttggtctcgg tggaacgttc cggaatgtac cacaggccag
      181 aggagcgaca cctgcacgct ggcccagcat ggcggacccc gcagaggtgg gacgctccgg
      241 aggcgcccac aggaggccgc aaggcggtgc tgtggccccg catcgtcgcc cgccccgtgg
      301 tttgcggtgg gccgctacgg aagcctttgc ttccttactt tgctggagac cagcatgctg
      361 gagtcaacat tcaagcagac caggactgct gcctcttcct ccagctgtgt ctctctgtct
      421 gcgcagttgc tttgatccat gtgggccgtc tttgagattc cctcctcgaa agcgccctca
      481 gcatgtcagc agcagcgaaa tcccaagtgc cggaggaggc agcgcctggc tgcgaggaag
      541 agcccaaggg aaaaacactt ctcacttggg ggtctctatt tggtcaccga agtgagaaga
      601 ttgtctttac caaaggtgat ggcagcccag aggagagctt gctcactgtc accatcacag
      661 agaccactgt cattgagtcg gatctgggtg tgtggagttc aagggctctc atctacctca
      721 cactgtggtt cttcttcagc ttctgtacac tgttcctcaa caaatacatc ctgtccctgt
      781 tagagggaga gcccagcatg ttaggtgctg tgcagatgct gtcaacaacg ttaattggat
      841 gtgttaaaat atttgttcct tgctgtttat atcaacacaa aacccggctt tcttacccac
      901 ccaatttcat catgactatg ctctttgtgg gcctcatgag gtttgcaacg gtggttttgg
      961 ggctggtcag cctcaagaat gtggcagtgt cctttgctga gacagtgaag agctcggctc
     1021 ccattttcac ggtgatcatg tctcggatga ttctggggga gtacacaggg ctgctggtca
     1081 acctgtccct cattccagtc atgggaggac tagcgttgtg cactgccacg gaaataagct
     1141 tcaacatcct ggggttttca gctgcgttat ccaccaacat tatggattgt ttgcagaatg
     1201 ttttttcaaa aaagcttctc agtggggaca aataccggtt ctcggccccg gaactgcagt
     1261 tctacaccag tgctgctgct gtggccttgc tcattccagc atggaccttc ttcatggata
     1321 tccctgtgat tggaaggagt gggaagagct tcagctacag ccaggacatc gtgctgttgc
     1381 tgctgacaga tggcgccttg tttcaccttc agagtgtcac tgcatatgcc ctgatgggaa
     1441 agatctcccc tgtgacgttc agtgtcgcca gtactgtgaa gcacgccttg tctatctggc
     1501 tcagcatcat cgtttttgga aacaaaatca ctagcctgtc tgccattggc accatccttg
     1561 tcacattggg tgtcttgctc tacaacaagg ccaggcagta tcagcaggag actatgcaga
     1621 gtctggtcac agccaccagc cgaaacccag aagatgacac agagcccctt gttccccagg
     1681 actctagaca gcaccactga tcacctgatg ctgtgtagat ccaggcctag atgttccttc
     1741 tgtactagag ggaaatgatg cagggcaggt ctctcgctcc ttcctggaaa tcagatgggg
     1801 aatttgggac tcagcttctg cctggcagag caccacagga ccaaatgatc tacagcttcc
     1861 ctggctgcaa gtgaaccagt gtctccgtgc ccagcctgca ctgtggaata agcacaggct
     1921 ccaggatcaa cccgagttgc tgtctgtttg atgccatcca ggagacctaa acttttctat
     1981 caccaccacc accaccacca ccaccaccat ggaagcctct tggttcttga cagtctatga
     2041 aacagacatt ccagatgcca atgactctag catggagcca taaaacccag agtagcaggc
     2101 agaagagaca agtttctcct gccacggaga gacagtgctg tgtgaaggag aagtgtctcc
     2161 tccttggcct gtgctacatt gaactaccct gctccagggt tgttgtccca tgtttctgct
     2221 accattttgt gattgcccat tctgggaagt tggcagcaaa tctctaattc aagcagatgg
     2281 tctggagtgc ttttccattt taagtatgtg aatgtgaagc gggcgattct gaatggcaca
     2341 gtggctgccc tatgaagatt tcccttcagg atgcttgata gggacgttct gacgagcatt
     2401 tgagtgttta taggctatgc tgtagttaaa gggacacttc tttttgatgt agcaggtgcc
     2461 tgtcgaggtt tctctgtgtc tccatgtaag gtacatcaaa gtgtacatgc acaactaact
     2521 cttcaccagg gatcatatga tgactgcctg agccaccagg tctccagagc ttaaggtgga
     2581 gtggaggaca acagtgggcc ttgggttaac acgctgaggt tctacattat tcggcatttt
     2641 gtgagttgtg tgtggggtgc agtctgttgc tagccagtct ctaagactcc attacttaca
     2701 agctgcagcc actggcactc cttgtccagg tctcactggt cctccctgct ctaagtcttt
     2761 cgtgcacatg gtggttcaaa aagataatgg ggtgaaaaag agcaataatt atgtctacat
     2821 tttatttact tgaaaaagcc atctgccatg atgatggatc aaaatgaggc cttttaatcc
     2881 ataagccaac ttttaaaaga agctgatgtg tgctggacat cagctaggtg tatctttact
     2941 atgctatgta aagatattgt gaagatgttc tctcatttga ctttgcccag gtttctagtt
     3001 ccttcctctt tgctcttctc aaaataaaga tccagtggag gacagatggc agacgttgga
     3061 ttaatctgtg tagacctgtc tgctcaagat ctggctgtgg agctgctgac accgaagagc
     3121 acgtgcttgt gggtattggt tggcagagct cttctggcct tcccgcagac ctgtctaagt
     3181 atgctcagag ctctacatgc ctggcttctt actattattt ggaatttctg cctgtgtcct
     3241 atgtttaatt aggaaatgac ctattgtgac ttgctctggc catccctccc ccatgtcaca
     3301 agactcagct tgttttgatt ttcttaaggt ttgggctaga aacaaaaaca aagatttttc
     3361 ttaaagcaat tttctctaaa gctgctttga gacttttcct cataggtgga aagatcatgg
     3421 aatcagctgc ttccttcagg tcttccagga cagggctggg ttgagaatcg tggaacggcc
     3481 ctgcttgacc atttgttatg actataccat aacaatacat ttttaattga ctttgttagt
     3541 actttcatag aatactatgt tcttcatgaa ttgttactga tgtaaatgta caaatattga
     3601 caccacgtgt cattccttgt cctggataat tcctcctgag tttatgtcat tgtctggtct
     3661 gttgtaaaca gaacactgga ttgaccttct gagccagcta gctgcttact cactgcacgc
     3721 atagttaaaa gatatacaca tttctaattt caaaaatagt tctaggagct acagagatgg
     3781 ccgagtggtt atgtttcttg ctgaggaccc aagttcagtt cccagaactc atgtagagtg
     3841 tttcaccaac ttcctataac ttcagcatta gggattctaa tgcctctggc ttctctgggc
     3901 atctgcacac tggcttgtgt atgaacacac acacatatac acacacacat atatcttaaa
     3961 aataagtaca tttgctaggg gaggtggtgc aagcctttaa tcccagcact tgggaatcag
     4021 aggcatgtgg atctctgagt ttgagggcag tctggactac agaacaagtt ccaggacagc
     4081 cagggcaaca cagagaaaag cctgtcttga aaaaccagat aaatagataa ataaaattta
     4141 aaaacgtcca tgatttgggg tataccttag tggcacatca ctggcatgta ttgtgaagct
     4201 cttgggttga tcaccagcag cagatgtggg acagaaagat aaaggggaga caacaaaaat
     4261 aaccccaaaa cttctaatac taaaagacaa ggaaacgttt ttgttttttg ggtttttttg
     4321 tttttttttt gtttggttgg tttttttttt ttttttttgg tttttcaaga cagggtttct
     4381 ctgtatagtc ctggctgtcc tggaactcac tttgtagacc aggctggcct cgaactcaga
     4441 aatccgcctg tctctgcctc ccaagtgctg ggattaaagg cgtgcgccac cactgcccgg
     4501 ccggaaagta tttttttaat tcattgtttt gcctgcatgt gtgtctttat gagggtgttg
     4561 gatcccctga aattggagtt acagataatt atgagctgcc atgttgctcc tgggaattga
     4621 attcgggtcg tcttgaagat cagccatctt accagctcct gttttgtttg tttttaaacc
     4681 cgatcatgat ggcacataca tataatctta gtaatttgga agcataagag tgcatagtgg
     4741 ttcaaggcca gcttgggcta catattgaga ccaagtttca aaaaaatgtt tatgatcaca
     4801 atttctcaaa tattaggatt atcatctgtc ttcagatggt ggttcacact tttaatccca
     4861 gcacttagga ggcagaggca ggtgattctc tgtgagtttg aggctagact ggtctacaaa
     4921 gccaaatcca ggacccccag ggctctgtta cacagaaaaa ccttgtctca agaaaagtaa
     4981 aaatgatgag tcagaggaga ttaaagagaa ttaaagctgt tcaagggatt cggccaagta
     5041 aactttactt tgtgccttaa aaacagcaca aaacaagtgg ctttgtgatc ctgctctcag
     5101 atgatcactt tgctcagtga taataacaga tgctcagcac agcctcctgt cacatctgtc
     5161 caagtgatgt cttctttttt tttttgttgt ttttttttgt tttttttttt tgtttttgga
     5221 gacagggttt ctctgtgtag ccatggctgt cctggaactc actttgtaga ccaggctggc
     5281 ctcgaactca gaaatccacc tgcctctgtc tcccgagtgc taggattaaa ggcgtgcgcc
     5341 accaccgccc agcaagtgat gtcttcttaa cattggaaag gggtaaagaa agatgttagt
     5401 acagatggga aacaatgccg gctcctcctg agattgcatt tacctatgta acccatagtg
     5461 tccttgaact ctagattctt ctaagtcatc gttctcagga ctgagattac aagtacgtgt
     5521 caccacttct gactcctgcc tttgaacatc aatcttttgt tttttcttaa cacgtaaata
     5581 ttgatctccc tgtgaggcgg cctcttcatc tcttcattct cccacccttc gtttattatg
     5641 ctaggcatag tactcagggc ttcaggaatg ctaggctgct attctttctc tgagacatgg
     5701 cctccagcct gtttttctta gtttatcaat gcctttgctc tccccatgaa ttagaacagg
     5761 acatgctgat tgtggacaaa tagtatccac cacaattaga gtgtagtagg ttttaacttc
     5821 agtgtctctg aagtacgttt tcctgggtac tctgatcctg actttgccag ctgctggacc
     5881 cttcctaata tgtccaagtt tagtttgaat taaatcaagt tggctagttg tgtgtttgtg
     5941 gggtttttgt ttgtttttac ttttcatttc tgggactcaa gctgcatact aaattcattt
     6001 gtaatgtctg gacttaataa taatgtaatt gtgagtatgt tcgttcaatg ttcgttcaat
     6061 gttggcactt tggaaaaggc cacagtttag ggtggacaat tgtctgcatc aaagccaagt
     6121 catatttgct ttataccaaa caatactaga gaattaaaac acatcataaa atgtacactg
     6181 ttttgtattt cacctctttc agtatttaaa taattatatt aatgcctcct agaaaagaat
     6241 tctgttagat aattcagtga ttcctgaaat aaattggtat tgtgtaatta aaaaaaaaaa
     6301 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//
