LOCUS       NM_001403015            2290 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus solute carrier family 35, member B3 (Slc35b3),
            transcript variant 7, mRNA.
ACCESSION   NM_001403015 XM_006516529
VERSION     NM_001403015.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2290)
  AUTHORS   Sasaki,N., Hirano,T., Ichimiya,T., Wakao,M., Hirano,K.,
            Kinoshita-Toyoda,A., Toyoda,H., Suda,Y. and Nishihara,S.
  TITLE     The 3'-phosphoadenosine 5'-phosphosulfate transporters, PAPST1 and
            2, contribute to the maintenance and differentiation of mouse
            embryonic stem cells
  JOURNAL   PLoS One 4 (12), e8262 (2009)
   PUBMED   20011239
  REMARK    GeneRIF: PAPST-dependent sulfation of heparan sulfate or
            chondroitin sulfate chains regulates the extrinsic signaling
            required for the maintenance and normal differentiation of mouse
            embryonic stem cells.[PAPST1, PAPST2]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2290)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   3  (bases 1 to 2290)
  AUTHORS   Bailey,P.J., Klos,J.M., Andersson,E., Karlen,M., Kallstrom,M.,
            Ponjavic,J., Muhr,J., Lenhard,B., Sandelin,A. and Ericson,J.
  TITLE     A global genomic transcriptional code associated with CNS-expressed
            genes
  JOURNAL   Exp Cell Res 312 (16), 3108-3119 (2006)
   PUBMED   16919269
REFERENCE   4  (bases 1 to 2290)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125223.3.
            
            On Mar 24, 2022 this sequence version replaced XM_006516529.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR12282455.37573294.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-370               AC125223.3         56409-56778
            371-658             AC125223.3         61005-61292
            659-780             AC125223.3         62711-62832
            781-873             AC125223.3         65079-65171
            874-1028            AC125223.3         72287-72441
            1029-1136           AC125223.3         73775-73882
            1137-1234           AC125223.3         76969-77066
            1235-1327           AC125223.3         79102-79194
            1328-1439           AC125223.3         79588-79699
            1440-1509           AC125223.3         82134-82203
            1510-2290           AC125223.3         84025-84805
FEATURES             Location/Qualifiers
     source          1..2290
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 18.61 cM"
     gene            1..2290
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
                     /note="solute carrier family 35, member B3"
                     /db_xref="GeneID:108652"
                     /db_xref="MGI:MGI:1913978"
     exon            1..370
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
                     /inference="alignment:Splign:2.1.0"
     exon            371..658
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
                     /inference="alignment:Splign:2.1.0"
     CDS             458..1660
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
                     /note="isoform 2 is encoded by transcript variant 7;
                     adenosine 3'-phospho 5'-phosphosulfate transporter 2; PAPS
                     transporter 2"
                     /codon_start=1
                     /product="adenosine 3'-phospho 5'-phosphosulfate
                     transporter 2 isoform 2"
                     /protein_id="NP_001389944.1"
                     /db_xref="GeneID:108652"
                     /db_xref="MGI:MGI:1913978"
                     /translation="MDLKFNNSRKYVSISVPSKTQAMSPHIKSVEDVVVLGVNLSKFS
                     KLTQFLICVAGVFVFYLIYGYLQELIFSVEGFKPYGWYLTLVQFAFYSVFGLIELQLT
                     QDRRRSPVSPSVSFFSVYEYRWSSLSGTPWFITFIPRIPGKTYMLIAFLTVGTMGLSN
                     TSLGYLNYPTQVIFKCCKLIPVMLGGVFIQGKRYNLADVSAAVCMSLGLIWFTLADST
                     IAPNFNLTGVMLISLALCADAVIGNVQEKAMKLHNASNSEMVLYSYSIGFVYILLGLS
                     CTSGLGPAVAFCSKNPVGTYGYAFLFSLTGYFGISFVLALIKIFGALLAVTVTTGRKA
                     MTVVLSFLFFAKPFTFQYIWSGLLVVLGIFLNVYSKNMDKIRLPSVYNMIKKAMDMKK
                     SRTLAQTV"
     exon            659..780
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
                     /inference="alignment:Splign:2.1.0"
     exon            781..873
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
                     /inference="alignment:Splign:2.1.0"
     exon            874..1028
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1136
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
                     /inference="alignment:Splign:2.1.0"
     exon            1137..1234
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
                     /inference="alignment:Splign:2.1.0"
     exon            1235..1327
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
                     /inference="alignment:Splign:2.1.0"
     exon            1328..1439
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..1509
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
                     /inference="alignment:Splign:2.1.0"
     exon            1510..2290
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2093..2098
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
                     /note="hexamer: AATAAA"
     polyA_site      2121
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
                     /note="major polyA site"
     regulatory      2267..2272
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
                     /note="hexamer: AATAAA"
     polyA_site      2290
                     /gene="Slc35b3"
                     /gene_synonym="4921526O06Rik; CGI-19; PABST2; PAPST2"
ORIGIN      
        1 agtggcgcgc agggtccggc gtgtgaagac cttccgggga ggtggcggcc gaggcggccg
       61 tcgcgggagc agacccggag gcggagacgg agaccgagga ggtgacagcg gcggagctgg
      121 gaggtggggg tcttgctgcg cggccaggcg tcgtcaggca gaactcgggt gggctcccac
      181 accgtgtcaa cagagaaggt ggacgccgcc gccgtcgggg tggtcggggc gcgcgcttcc
      241 gggaagagca tcgttccctg ttggcctgag aacccccggg ccggacccct cctctaccct
      301 gctctctgtg ctcagagact tggtctctcg gattcccttg gctgtttttg cagttcagag
      361 tcatttccgg gcccagccag cagaagaaag acaggacgaa gcatccgaaa agagcagaga
      421 ccaagttgca ggccttgact gtggcagagc agaaacaatg gacctcaagt tcaacaactc
      481 caggaagtat gtctccatct cagtgccctc caaaacgcag gccatgtcgc cgcacatcaa
      541 gtcagttgag gacgtcgtgg tgctgggcgt gaacctcagc aagtttagca agctcacaca
      601 gtttctcatc tgtgtggctg gagtttttgt attttaccta atttatggat acttacagga
      661 gctgatcttt tcagtggaag gctttaagcc ttacggctgg taccttacct tagtgcagtt
      721 tgccttttac tccgtatttg gcctaatcga gctacagctc actcaggaca gaaggagaag
      781 tccagtgtca ccttcagtgt ctttcttcag tgtctacgag tatcgttgga gcagtctttc
      841 aggaactcct tggtttatta catttattcc tagaatacca ggaaaaacct acatgctaat
      901 agcttttcta actgtgggta ctatgggctt atcaaacact tccttgggct acctgaatta
      961 cccaacccaa gtcatcttca agtgctgcaa actgattcct gttatgctag gaggagtttt
     1021 tattcaagga aagcggtaca accttgcaga tgtgtctgcc gcagtgtgca tgagcctggg
     1081 cctgatctgg tttaccctcg ctgacagcac aattgcacca aactttaatc tgacaggtgt
     1141 gatgcttatc tccctggcgc tgtgtgcaga cgctgtcatt gggaacgttc aggagaaggc
     1201 catgaaactg cacaatgctt ccaactcgga gatggttttg tattcctact caatcgggtt
     1261 tgtgtacatt ttgctgggac tgtcatgcac tagtggactg ggccctgcag tggcattttg
     1321 ttcaaagaac cctgttggga cttacggcta cgccttcctg ttttccctca ctggatactt
     1381 tgggatctcc tttgttctgg ccctcattaa aatcttcggt gcacttctgg ctgtaacagt
     1441 gacaacagga aggaaagcaa tgaccgttgt cctgtccttc ctgttctttg ctaagccgtt
     1501 cacttttcag tatatatggt ctggcttgtt agttgtcctt ggcatatttc tcaatgttta
     1561 cagcaaaaat atggataaaa taagattgcc atcggtgtac aacatgataa agaaagccat
     1621 ggacatgaaa aagtcaagga cgttggcaca gactgtgtag gaactgtgtt ctcctattta
     1681 aaataaagct ctgtgggaac aaccattaat caattcactt tgcaaaggct tgtgatacaa
     1741 accaaaggat ctgaaggccg ctgtcagatg agcagattgt acatccagtg gttccttggc
     1801 atccacctct acagaataca ggcttttgat caactccaaa tgatcaagag cccacaccta
     1861 ggacgtgttg caataaagtc agtatgaagg aaagtgcttc ctagcaatgt tctgaacatt
     1921 tcactggaaa tggaccgtgt tgtaagactg attggaaatc ctcccagcct gcagcgcggt
     1981 actgtgagtg gcactgtgtc tccattccgt tttgctggtg ttatttaaat tcttctctgt
     2041 tataagagtg aactgatgat ttgaagtgta gagaaaatac cattcattta taaataaaat
     2101 tatcctgtga ttttttttaa atggtgtttt aatagaattt gttatggcag agaatggaga
     2161 tgggatgaag ggctaatgta tactttaaaa cttgggtttt taaagttttg agaaaataac
     2221 attcacttaa ataaaattat cctctcattt ttaaaaaaaa tgtattaata aaatttgtta
     2281 ttgaagaaaa
//
