LOCUS       NM_078484               1569 bp    mRNA    linear   ROD 17-APR-2023
DEFINITION  Mus musculus solute carrier family 35 (UDP-galactose transporter),
            member A2 (Slc35a2), transcript variant 1, mRNA.
ACCESSION   NM_078484
VERSION     NM_078484.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1569)
  AUTHORS   Cheng H, Wang S, Gao D, Yu K, Chen H, Huang Y, Li M, Zhang J and
            Guo K.
  TITLE     Nucleotide sugar transporter SLC35A2 is involved in promoting
            hepatocellular carcinoma metastasis by regulating cellular
            glycosylation
  JOURNAL   Cell Oncol (Dordr) 46 (2), 283-297 (2023)
   PUBMED   36454514
  REMARK    GeneRIF: Nucleotide sugar transporter SLC35A2 is involved in
            promoting hepatocellular carcinoma metastasis by regulating
            cellular glycosylation.
REFERENCE   2  (bases 1 to 1569)
  AUTHORS   Hayashi Y, Ito Y, Yanagiba Y, Kamijima M, Naito H and Nakajima T.
  TITLE     Differences in metabolite burden of di(2-ethylhexyl)phthalate in
            pregnant and postpartum dams and their offspring in relation to
            drug-metabolizing enzymes in mice
  JOURNAL   Arch Toxicol 86 (4), 563-569 (2012)
   PUBMED   22159897
  REMARK    GeneRIF: DEHP exposure did not influence lipase activity, whereas
            it slightly enhanced UGT activity and exclusively increased CYP4A14
            levels in pregnant and/or postpartum dams.
REFERENCE   3  (bases 1 to 1569)
  AUTHORS   Oelmann S, Stanley P and Gerardy-Schahn R.
  TITLE     Point mutations identified in Lec8 Chinese hamster ovary
            glycosylation mutants that inactivate both the UDP-galactose and
            CMP-sialic acid transporters
  JOURNAL   J Biol Chem 276 (28), 26291-26300 (2001)
   PUBMED   11319223
REFERENCE   4  (bases 1 to 1569)
  AUTHORS   Means GD, Toy DY, Baum PR and Derry JM.
  TITLE     A transcript map of a 2-Mb BAC contig in the proximal portion of
            the mouse X chromosome and regional mapping of the scurfy mutation
  JOURNAL   Genomics 65 (3), 213-223 (2000)
   PUBMED   10857745
REFERENCE   5  (bases 1 to 1569)
  AUTHORS   Ishida N, Yoshioka S, Iida M, Sudo K, Miura N, Aoki K and Kawakita
            M.
  TITLE     Indispensability of transmembrane domains of Golgi UDP-galactose
            transporter as revealed by analysis of genetic defects in
            UDP-galactose transporter-deficient murine had-1 mutant cell lines
            and construction of deletion mutants
  JOURNAL   J Biochem 126 (6), 1107-1117 (1999)
   PUBMED   10578063
REFERENCE   6  (bases 1 to 1569)
  AUTHORS   Ishida N, Miura N, Yoshioka S and Kawakita M.
  TITLE     Molecular cloning and characterization of a novel isoform of the
            human UDP-galactose transporter, and of related complementary DNAs
            belonging to the nucleotide-sugar transporter gene family
  JOURNAL   J Biochem 120 (6), 1074-1078 (1996)
   PUBMED   9010752
REFERENCE   7  (bases 1 to 1569)
  AUTHORS   Lennon G, Auffray C, Polymeropoulos M and Soares MB.
  TITLE     The I.M.A.G.E. Consortium: an integrated molecular analysis of
            genomes and their expression
  JOURNAL   Genomics 33 (1), 151-152 (1996)
   PUBMED   8617505
REFERENCE   8  (bases 1 to 1569)
  AUTHORS   Hara T, Yamauchi M, Takahashi E, Hoshino M, Aoki K, Ayusawa D and
            Kawakita M.
  TITLE     The UDP-galactose translocator gene is mapped to band
            Xp11.23-p11.22 containing the Wiskott-Aldrich syndrome locus
  JOURNAL   Somat Cell Mol Genet 19 (6), 571-575 (1993)
   PUBMED   8128316
REFERENCE   9  (bases 1 to 1569)
  AUTHORS   Hara T, Hattori S and Kawakita M.
  TITLE     Isolation and characterization of mouse FM3A cell mutants which are
            devoid of Newcastle disease virus receptors
  JOURNAL   J Virol 63 (1), 182-188 (1989)
   PUBMED   2535724
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF229634.1, CB723945.1 and BX512781.1.
            
            [WARNING] On Dec 5, 2023 this sequence was replaced by NM_078484.3.
            
            On Apr 14, 2007 this sequence version replaced NM_078484.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF229634.1, SRR7652917.231903.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1151              AF229634.1         1-1151
            1152-1523           CB723945.1         141-512
            1524-1569           BX512781.1         332-377
FEATURES             Location/Qualifiers
     source          1..1569
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 3.56 cM"
     gene            1..1569
                     /gene="Slc35a2"
                     /gene_synonym="Had-1; Had1; Sfc8; Ugalt; UGT"
                     /note="solute carrier family 35 (UDP-galactose
                     transporter), member A2"
                     /db_xref="GeneID:22232"
                     /db_xref="MGI:MGI:1345297"
     exon            1..190
                     /gene="Slc35a2"
                     /gene_synonym="Had-1; Had1; Sfc8; Ugalt; UGT"
                     /inference="alignment:Splign:2.1.0"
     CDS             100..1281
                     /gene="Slc35a2"
                     /gene_synonym="Had-1; Had1; Sfc8; Ugalt; UGT"
                     /note="isoform 1 is encoded by transcript variant 1;
                     solute carrier family 35 (UDP-galactose transporter)
                     member 2; mUGT1; UDP-Gal-Tr; solute carrier family 35
                     member A2; solute carrier family 35 (UDP-galactose
                     transporter), member 2; UDP-galactose translocator; solute
                     carrier family (UDP-N-acetylglucosamine transporter),
                     member 2"
                     /codon_start=1
                     /product="UDP-galactose translocator isoform 1"
                     /protein_id="NP_511039.2"
                     /db_xref="CCDS:CCDS52986.1"
                     /db_xref="GeneID:22232"
                     /db_xref="MGI:MGI:1345297"
                     /translation="MAAVGVGGSTAAAGAGAVSSGALEPGSTTAAHRRLKYISLAVLV
                     VQNASLILSIRYARTLPGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLH
                     EAVLVQYVDTLKLAVPSLIYTLQNNLQYVAISNLPAATFQVTYQLKILTTALFSVLML
                     NRSLSRLQWASLLLLFTGVAIVQAQQAGGSGPRPLDQNPGAGLAAVVASCLSSGFAGV
                     YFEKILKGSSGSVWLRNLQLGLFGTALGLVGLWWAEGTAVASQGFFFGYTPAVWGVVL
                     NQAFGGLLVAVVVKYADNILKGFATSLSIVLSTVASIRLFGFHLDPLFALGAGLVIGA
                     VYLYSLPRGAVKAIASASASGPCIHQQPPGQPPPPQLSSRGDLTTEPFLPKLLTKVKG
                     S"
     exon            191..373
                     /gene="Slc35a2"
                     /gene_synonym="Had-1; Had1; Sfc8; Ugalt; UGT"
                     /inference="alignment:Splign:2.1.0"
     exon            374..525
                     /gene="Slc35a2"
                     /gene_synonym="Had-1; Had1; Sfc8; Ugalt; UGT"
                     /inference="alignment:Splign:2.1.0"
     exon            526..1253
                     /gene="Slc35a2"
                     /gene_synonym="Had-1; Had1; Sfc8; Ugalt; UGT"
                     /inference="alignment:Splign:2.1.0"
     exon            1254..1555
                     /gene="Slc35a2"
                     /gene_synonym="Had-1; Had1; Sfc8; Ugalt; UGT"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccagctaacg ccccgccccc cccagaggtc cggaaacgga cgtgatggat acggaagtag
       61 cctgctgttg ccgaggggac gggacgggca gatgccaaca tggcagcggt tggggttggt
      121 ggatctaccg ctgcggccgg ggctggggct gtgtcctcgg gcgcgttgga acctgggtcc
      181 actacagcgg ctcaccggcg cctcaagtat atatccttag ctgtgctggt ggtccagaat
      241 gcctccctca tcctcagcat ccgctacgct cgcacactgc ctggggaccg cttctttgcc
      301 accactgctg tggtcatggc tgaagtgctc aaaggtctca cctgtctcct gctgctcttc
      361 gcacaaaaga ggggtaatgt gaagcacctg gtcctcttcc tccatgaggc tgtcctggtc
      421 caatatgtgg acacactcaa gcttgcggtg ccctctctca tctatacctt gcagaataac
      481 ctccagtatg ttgccatcag caacctgcca gctgccactt tccaggtgac atatcagctg
      541 aagatcctga ctacagcgct cttctctgtg ctcatgttga atcgcagcct ctcacgcctg
      601 cagtgggcct ctctgctgct gctcttcact ggtgtcgcca ttgtccaggc acagcaagct
      661 ggtgggagtg gcccacggcc actggatcag aacccggggg cgggcttagc ggcagttgtg
      721 gcctcctgtc tctcctcagg cttcgctggg gtctactttg agaagatcct caaaggcagc
      781 tcaggttctg tgtggcttcg taacctacag ctcggcctct ttggcacagc gctgggcctg
      841 gtggggctct ggtgggctga gggcaccgcc gtggccagtc aaggcttctt ctttgggtac
      901 acacctgctg tctggggtgt agtactaaac caagcctttg gtgggcttct ggtggctgtt
      961 gttgtcaagt atgctgacaa catcctcaag ggctttgcca cctccctgtc tattgtgctg
     1021 tccactgttg cctccattcg cctctttggc ttccacctgg acccattatt tgccctgggc
     1081 gctgggctcg tcattggtgc tgtctacctc tacagccttc cccgaggtgc agtcaaagcc
     1141 atagcctcgg cctcggcctc tgggccctgc attcaccagc agcctcctgg gcagccacca
     1201 ccaccgcagc tgtcttctcg aggagacctc accacggagc cctttctgcc aaagttgctc
     1261 accaaggtga aggggtcgta gctgctggac ttgaagatgc tggcctgtct tcgttctccc
     1321 ttcttgccct ggcccaactg ggactaaact cttatcagta ttaggggtag ggtgaggtag
     1381 acacgggaac tccctgtcct taccaacccc tgccccacat agggctgaca tgactaacct
     1441 ctgttaatgg gcccacctct actcctgcta tctttacagt atttcttagg tgagtttctg
     1501 caaataaaat gttttgcacc ttgtgaagtt gggttggaaa gcctggaaag gatgaaaaaa
     1561 aaaaaaaaa
//
