LOCUS       NM_001081072            2598 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus solute carrier family 27 (fatty acid transporter),
            member 6 (Slc27a6), mRNA.
ACCESSION   NM_001081072 XM_128932
VERSION     NM_001081072.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2598)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2598)
  AUTHORS   Kappen,C., Kruger,C., Jones,S. and Salbaum,J.M.
  TITLE     Nutrient Transporter Gene Expression in the Early
            Conceptus-Implications From Two Mouse Models of Diabetic Pregnancy
  JOURNAL   Front Cell Dev Biol 10, 777844 (2022)
   PUBMED   35478964
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2598)
  AUTHORS   Lee,J.G., Kim,G., Park,S.G., Yon,J.M., Yeom,J., Song,H.E.,
            Cheong,S.A., Lim,J.S., Sung,Y.H., Kim,K., Yoo,H.J., Hong,E.J.,
            Nam,K.H., Seong,J.K., Kim,C.J., Nam,S.Y. and Baek,I.J.
  TITLE     Lipid signatures reflect the function of the murine primary
            placentationdagger
  JOURNAL   Biol Reprod 106 (3), 583-596 (2022)
   PUBMED   34850819
REFERENCE   4  (bases 1 to 2598)
  AUTHORS   Hilse,K.E., Rupprecht,A., Egerbacher,M., Bardakji,S.,
            Zimmermann,L., Wulczyn,A.E.M.S. and Pohl,E.E.
  TITLE     The Expression of Uncoupling Protein 3 Coincides With the Fatty
            Acid Oxidation Type of Metabolism in Adult Murine Heart
  JOURNAL   Front Physiol 9, 747 (2018)
   PUBMED   29988383
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2598)
  AUTHORS   Rutledge,E.A., Benazet,J.D. and McMahon,A.P.
  TITLE     Cellular heterogeneity in the ureteric progenitor niche and
            distinct profiles of branching morphogenesis in organ development
  JOURNAL   Development 144 (17), 3177-3188 (2017)
   PUBMED   28705898
REFERENCE   6  (bases 1 to 2598)
  AUTHORS   Mishima,T., Miner,J.H., Morizane,M., Stahl,A. and Sadovsky,Y.
  TITLE     The expression and function of fatty acid transport protein-2 and
            -4 in the murine placenta
  JOURNAL   PLoS One 6 (10), e25865 (2011)
   PUBMED   22028793
REFERENCE   7  (bases 1 to 2598)
  AUTHORS   DiRusso,C.C., Darwis,D., Obermeyer,T. and Black,P.N.
  TITLE     Functional domains of the fatty acid transport proteins: studies
            using protein chimeras
  JOURNAL   Biochim Biophys Acta 1781 (3), 135-143 (2008)
   PUBMED   18258213
REFERENCE   8  (bases 1 to 2598)
  AUTHORS   Schaiff,W.T., Knapp,F.F. Jr., Barak,Y., Biron-Shental,T.,
            Nelson,D.M. and Sadovsky,Y.
  TITLE     Ligand-activated peroxisome proliferator activated receptor gamma
            alters placental morphology and placental fatty acid uptake in mice
  JOURNAL   Endocrinology 148 (8), 3625-3634 (2007)
   PUBMED   17463056
REFERENCE   9  (bases 1 to 2598)
  AUTHORS   Schmuth,M., Ortegon,A.M., Mao-Qiang,M., Elias,P.M., Feingold,K.R.
            and Stahl,A.
  TITLE     Differential expression of fatty acid transport proteins in
            epidermis and skin appendages
  JOURNAL   J Invest Dermatol 125 (6), 1174-1181 (2005)
   PUBMED   16354187
REFERENCE   10 (bases 1 to 2598)
  AUTHORS   Jia,Z., Pei,Z., Li,Y., Wei,L., Smith,K.D. and Watkins,P.A.
  TITLE     X-linked adrenoleukodystrophy: role of very long-chain acyl-CoA
            synthetases
  JOURNAL   Mol Genet Metab 83 (1-2), 117-127 (2004)
   PUBMED   15464426
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC102231.12
            and AC158924.6.
            
            On Feb 6, 2007 this sequence version replaced XM_128932.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK028699.1, BC115435.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN00849387
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-705               AC102231.12        142528-143232
            706-909             AC102231.12        158317-158520
            910-1068            AC102231.12        166081-166239
            1069-1193           AC102231.12        168459-168583
            1194-1388           AC158924.6         213464-213658       c
            1389-1479           AC158924.6         207079-207169       c
            1480-1678           AC158924.6         204385-204583       c
            1679-1776           AC158924.6         202940-203037       c
            1777-1907           AC158924.6         202283-202413       c
            1908-2598           AC158924.6         199338-200028       c
FEATURES             Location/Qualifiers
     source          1..2598
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 33.71 cM"
     gene            1..2598
                     /gene="Slc27a6"
                     /gene_synonym="4732438L20Rik; FACVL2; FATP-6; FATP6;
                     mVLCS-H1; VLACS2; VLCS-H1; VLCSH1"
                     /note="solute carrier family 27 (fatty acid transporter),
                     member 6"
                     /db_xref="GeneID:225579"
                     /db_xref="MGI:MGI:3036230"
     exon            1..705
                     /gene="Slc27a6"
                     /gene_synonym="4732438L20Rik; FACVL2; FATP-6; FATP6;
                     mVLCS-H1; VLACS2; VLCS-H1; VLCSH1"
                     /inference="alignment:Splign:2.1.0"
     CDS             225..2084
                     /gene="Slc27a6"
                     /gene_synonym="4732438L20Rik; FACVL2; FATP-6; FATP6;
                     mVLCS-H1; VLACS2; VLCS-H1; VLCSH1"
                     /EC_number="6.2.1.3"
                     /EC_number="6.2.1.15"
                     /note="arachidonate--CoA ligase; fatty acid transport
                     protein 6; solute carrier family 27 member 6; very
                     long-chain acyl-CoA synthetase homolog 1;
                     fatty-acid-coenzyme A ligase, very long-chain 2;
                     long-chain-fatty-acid--CoA ligase"
                     /codon_start=1
                     /product="long-chain fatty acid transport protein 6"
                     /protein_id="NP_001074541.1"
                     /db_xref="CCDS:CCDS37828.1"
                     /db_xref="GeneID:225579"
                     /db_xref="MGI:MGI:3036230"
                     /translation="MLLSWLTGLGAGLLSLHFLQKLLFPYFWDDFWYLLKVVRYGIQM
                     EMYKLRGELVTVLDKFLSHTRKQPRKAFIIYEGDVYTYEDVDKRSNRIAHALLNHSSL
                     KRGDVVALLMSNEPDFVHVWFGLAKLGCVVAFLNSNLRFDSLLHCINTCEPTAVVVGG
                     DLLGSIEEILPSLPKHVRVWGMKDSVPEGIDSLQEKLSLASDEPVPPSHHVTSSLKST
                     CLYIFTSGTTGLPKAAVISQLQVLKGSVGLWAFGCTADDIIYITLPLYHSSGSLLGIG
                     GCVELGATCVLKKKFSASQFWNDCKKYNVTVFQYIGELCRYLCKQPQREGEKDHRVRL
                     AVGNGLSSDVWRQFLDRFGNIKMCELYGATEGNIVFMNHTGKIGSVGRANFFYSLFFS
                     FELIKYDFQKDEPWRNGQGWCSCVRKGEPGLLISRVNKKNPFFGYAGSDTHTKSKLLF
                     DVFRKGDVYFNTGDLMFQDQENFVYFWDRLGDTFRWKGENVATTEVADVLGRLDFIQE
                     ANVYGVRVPGYEGKAGMTSVILKPNKSLDLEKMYNQVVTSLPAYACPLFLRIQDKMET
                     TGTFKLKKLQLVEEGFDPLKISDPLYFMDNLKKSYVPLTEEIYNQIMSEEVKL"
     exon            706..909
                     /gene="Slc27a6"
                     /gene_synonym="4732438L20Rik; FACVL2; FATP-6; FATP6;
                     mVLCS-H1; VLACS2; VLCS-H1; VLCSH1"
                     /inference="alignment:Splign:2.1.0"
     exon            910..1068
                     /gene="Slc27a6"
                     /gene_synonym="4732438L20Rik; FACVL2; FATP-6; FATP6;
                     mVLCS-H1; VLACS2; VLCS-H1; VLCSH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1193
                     /gene="Slc27a6"
                     /gene_synonym="4732438L20Rik; FACVL2; FATP-6; FATP6;
                     mVLCS-H1; VLACS2; VLCS-H1; VLCSH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1194..1388
                     /gene="Slc27a6"
                     /gene_synonym="4732438L20Rik; FACVL2; FATP-6; FATP6;
                     mVLCS-H1; VLACS2; VLCS-H1; VLCSH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1389..1479
                     /gene="Slc27a6"
                     /gene_synonym="4732438L20Rik; FACVL2; FATP-6; FATP6;
                     mVLCS-H1; VLACS2; VLCS-H1; VLCSH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1480..1678
                     /gene="Slc27a6"
                     /gene_synonym="4732438L20Rik; FACVL2; FATP-6; FATP6;
                     mVLCS-H1; VLACS2; VLCS-H1; VLCSH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1679..1776
                     /gene="Slc27a6"
                     /gene_synonym="4732438L20Rik; FACVL2; FATP-6; FATP6;
                     mVLCS-H1; VLACS2; VLCS-H1; VLCSH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1777..1907
                     /gene="Slc27a6"
                     /gene_synonym="4732438L20Rik; FACVL2; FATP-6; FATP6;
                     mVLCS-H1; VLACS2; VLCS-H1; VLCSH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1908..2598
                     /gene="Slc27a6"
                     /gene_synonym="4732438L20Rik; FACVL2; FATP-6; FATP6;
                     mVLCS-H1; VLACS2; VLCS-H1; VLCSH1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtctagccca atgccccagg gcgtatcacc agcgttctgt agctttctgg gcgaaaacct
       61 ttgatttctt tcatgggata tacaaagaca tcttgagcca gaactacagg tgccagcctc
      121 tgagctttca ggacaggagt ctccagggca aaaagaggtg aaactcttgg aaaagaaaga
      181 gacactgcta ggacccatcg ggtctgctgg aggtctgggc acccatgctc ctgtcatggc
      241 tcacaggatt gggggctgga ctgctctccc tgcatttcct gcagaaactt ctgttcccgt
      301 atttctggga tgatttctgg tacttgctga aggtggtgcg ctacggaatt cagatggaga
      361 tgtacaaact gaggggggag ctggtcacgg tgctggataa gttcctgagc cacaccagga
      421 agcaaccacg gaaagccttc atcatttatg agggggacgt ctacacctac gaggacgtgg
      481 acaagaggag taacagaata gcccacgctc tcctgaacca ctcctcgctg aaaagggggg
      541 acgttgtggc tttgttgatg agcaacgagc ccgacttcgt tcatgtgtgg tttggcctgg
      601 ctaaactggg ctgcgtggtg gccttcctca actccaacct tcgcttcgat tccctcctac
      661 actgcatcaa cacctgtgaa cccactgccg tggtggtggg cggagatttg cttggaagca
      721 tagaagaaat acttcccagt ctcccaaaac acgtcagagt ttggggaatg aaggattctg
      781 ttccagaagg tatagattca ctccaagaaa agctgagtct cgcctctgat gagccagtac
      841 caccaagcca tcatgtcacc tcaagcctca agtctacttg cctctacatt tttacctctg
      901 gaacaacagg tctacccaaa gcagctgtga ttagccagtt gcaagtgttg aagggatctg
      961 ttgggctatg ggcgtttggc tgcacagctg atgacatcat ttatataacc ctccctctgt
     1021 accacagctc agggtctctc cttggaattg gtggatgtgt tgagttgggc gccacgtgtg
     1081 tgctaaagaa gaaattctcc gcaagccagt tttggaatga ttgcaagaag tacaacgtga
     1141 ctgtgtttca gtacattggg gaactttgcc gttatctgtg caaacagcct cagagagaag
     1201 gggaaaagga ccatcgggta cgtttggcag ttggaaacgg tttgagcagt gatgtgtgga
     1261 gacaattttt agacagattt ggaaatatta aaatgtgtga actgtacgga gctaccgaag
     1321 gaaacatagt cttcatgaac catactggga agattggatc tgtcgggaga gcaaatttct
     1381 tctacagtct ctttttctcc tttgagttga tcaagtatga ctttcagaaa gatgaaccat
     1441 ggcggaacgg acaaggctgg tgctcctgtg tgagaaaagg agaacctggt ctcctcattt
     1501 ctcgtgtgaa taagaagaat cccttcttcg gctacgctgg ctcggacacg cacacgaaaa
     1561 gcaagctgct ctttgatgtg tttcggaagg gagacgtgta cttcaacacc ggagacctaa
     1621 tgttccaaga ccaggagaac ttcgtttatt tttgggaccg tcttggagac actttcaggt
     1681 ggaaaggaga aaacgtcgca accacagagg tcgctgatgt gcttgggagg ttggacttca
     1741 tccaggaagc aaacgtgtac ggtgtgcgtg tgccaggtta tgaaggaaaa gcaggaatga
     1801 cttctgttat cctaaaacca aacaagtctt tagacttaga aaaaatgtac aaccaagtgg
     1861 tgacatctct gccagcttac gcctgcccac tgtttttaag aattcaggac aaaatggaaa
     1921 ctacagggac attcaagcta aagaagctac aactggtgga agaaggattt gatccgctga
     1981 agatttctga cccgctttac tttatggata acttgaaaaa atcttatgtc ccattgaccg
     2041 aagagattta taatcagata atgtcagagg aagttaaact gtaaagactg tctttgtggg
     2101 actttgatga cttcctggga aagatgaagg aagattcgtg agcttccttg tggacaatca
     2161 gggaggagtt ccttgcatta atcaatcata aatagaaaga aaattgtaca tgaagaatgc
     2221 tttgtagacc caagctttca aggcccccac tctgcagcac agtgggccat gaagtgggag
     2281 ctgtttgcct cgtggttatg ttatgaggct ggcttgagga tgccgcttac agacgctgcc
     2341 cggagtcacc aggaagcagc atacttcata gcatgagccc agagtacagc gatttctgaa
     2401 tgcgtttggg aagtaaaagc caacaggcca tagtattacc acctgactcc gggactcggg
     2461 gaaatgtgag gatttactct gaagcgagat ggggaagcag tgttcagcag gcgatgcatt
     2521 tccttcgcaa gcagaagttc cttgagttta atgaggctta aatttgcttt gattgacata
     2581 aactttagct gttttttt
//
