LOCUS       NM_001316688            2323 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus solute carrier family 27 (fatty acid transporter),
            member 3 (Slc27a3), transcript variant 2, mRNA.
ACCESSION   NM_001316688 XM_006501528
VERSION     NM_001316688.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2323)
  AUTHORS   Song,Z., Xiaoli,A.M., Li,Y., Siqin,G., Wu,T., Strich,R.,
            Pessin,J.E. and Yang,F.
  TITLE     The conserved Mediator subunit cyclin C (CCNC) is required for
            brown adipocyte development and lipid accumulation
  JOURNAL   Mol Metab 64, 101548 (2022)
   PUBMED   35863637
REFERENCE   2  (bases 1 to 2323)
  AUTHORS   Kappen,C., Kruger,C., Jones,S. and Salbaum,J.M.
  TITLE     Nutrient Transporter Gene Expression in the Early
            Conceptus-Implications From Two Mouse Models of Diabetic Pregnancy
  JOURNAL   Front Cell Dev Biol 10, 777844 (2022)
   PUBMED   35478964
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2323)
  AUTHORS   Mishima,T., Miner,J.H., Morizane,M., Stahl,A. and Sadovsky,Y.
  TITLE     The expression and function of fatty acid transport protein-2 and
            -4 in the murine placenta
  JOURNAL   PLoS One 6 (10), e25865 (2011)
   PUBMED   22028793
REFERENCE   4  (bases 1 to 2323)
  AUTHORS   Han,L.Q., Li,H.J., Wang,Y.Y., Zhu,H.S., Wang,L.F., Guo,Y.J.,
            Lu,W.F., Wang,Y.L. and Yang,G.Y.
  TITLE     mRNA abundance and expression of SLC27A, ACC, SCD, FADS, LPIN,
            INSIG, and PPARGC1 gene isoforms in mouse mammary glands during the
            lactation cycle
  JOURNAL   Genet Mol Res 9 (2), 1250-1257 (2010)
   PUBMED   20603810
  REMARK    GeneRIF: analysis of mRNA abundance and expression of SLC27A, ACC,
            SCD, FADS, LPIN, INSIG, and PPARGC1 gene isoforms in mouse mammary
            glands during the lactation cycle
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2323)
  AUTHORS   Schaiff,W.T., Knapp,F.F. Jr., Barak,Y., Biron-Shental,T.,
            Nelson,D.M. and Sadovsky,Y.
  TITLE     Ligand-activated peroxisome proliferator activated receptor gamma
            alters placental morphology and placental fatty acid uptake in mice
  JOURNAL   Endocrinology 148 (8), 3625-3634 (2007)
   PUBMED   17463056
REFERENCE   6  (bases 1 to 2323)
  AUTHORS   Schmuth,M., Ortegon,A.M., Mao-Qiang,M., Elias,P.M., Feingold,K.R.
            and Stahl,A.
  TITLE     Differential expression of fatty acid transport proteins in
            epidermis and skin appendages
  JOURNAL   J Invest Dermatol 125 (6), 1174-1181 (2005)
   PUBMED   16354187
REFERENCE   7  (bases 1 to 2323)
  AUTHORS   Pei,Z., Fraisl,P., Berger,J., Jia,Z., Forss-Petter,S. and
            Watkins,P.A.
  TITLE     Mouse very long-chain Acyl-CoA synthetase 3/fatty acid transport
            protein 3 catalyzes fatty acid activation but not fatty acid
            transport in MA-10 cells
  JOURNAL   J Biol Chem 279 (52), 54454-54462 (2004)
   PUBMED   15469937
  REMARK    GeneRIF: studies cast doubt on the designation of very long-chain
            acyl-CoA synthetase 3 (ACSVL3) as a fatty acid transport protein
REFERENCE   8  (bases 1 to 2323)
  AUTHORS   Jia,Z., Pei,Z., Li,Y., Wei,L., Smith,K.D. and Watkins,P.A.
  TITLE     X-linked adrenoleukodystrophy: role of very long-chain acyl-CoA
            synthetases
  JOURNAL   Mol Genet Metab 83 (1-2), 117-127 (2004)
   PUBMED   15464426
REFERENCE   9  (bases 1 to 2323)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Kitamura,H., Nakagawa,T., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of FLJ
            genes: the complete nucleotide sequences of 110 mouse
            FLJ-homologous cDnas identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (2), 127-135 (2004)
   PUBMED   15449545
REFERENCE   10 (bases 1 to 2323)
  AUTHORS   Hirsch,D., Stahl,A. and Lodish,H.F.
  TITLE     A family of fatty acid transporters conserved from mycobacterium to
            man
  JOURNAL   Proc Natl Acad Sci U S A 95 (15), 8625-8629 (1998)
   PUBMED   9671728
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC145082.10.
            
            On Jan 23, 2023 this sequence version replaced NM_001316688.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK037042.1, SRR7345562.4146308.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-798               AC145082.10        84041-84838         c
            799-1030            AC145082.10        83559-83790         c
            1031-1189           AC145082.10        83197-83355         c
            1190-1314           AC145082.10        82505-82629         c
            1315-1509           AC145082.10        82124-82318         c
            1510-1600           AC145082.10        81933-82023         c
            1601-1799           AC145082.10        81617-81815         c
            1800-1897           AC145082.10        81349-81446         c
            1898-2028           AC145082.10        81119-81249         c
            2029-2323           AC145082.10        80108-80402         c
FEATURES             Location/Qualifiers
     source          1..2323
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 39.22 cM"
     gene            1..2323
                     /gene="Slc27a3"
                     /gene_synonym="Acsvl3; FATP-3; FATP3; Vlcs-3"
                     /note="solute carrier family 27 (fatty acid transporter),
                     member 3"
                     /db_xref="GeneID:26568"
                     /db_xref="MGI:MGI:1347358"
     exon            1..798
                     /gene="Slc27a3"
                     /gene_synonym="Acsvl3; FATP-3; FATP3; Vlcs-3"
                     /inference="alignment:Splign:2.1.0"
     CDS             589..2205
                     /gene="Slc27a3"
                     /gene_synonym="Acsvl3; FATP-3; FATP3; Vlcs-3"
                     /EC_number="6.2.1.3"
                     /EC_number="6.2.1.15"
                     /note="isoform 2 is encoded by transcript variant 2; very
                     long-chain acyl-CoA synthetase homolog 3; long-chain fatty
                     acid transport protein 3; mFLJ00207 protein; solute
                     carrier family 27 member 3; long-chain-fatty-acid--CoA
                     ligase; arachidonate--CoA ligase"
                     /codon_start=1
                     /product="long-chain fatty acid transport protein 3
                     isoform 2"
                     /protein_id="NP_001303617.1"
                     /db_xref="GeneID:26568"
                     /db_xref="MGI:MGI:1347358"
                     /translation="MRLLEGRPRPLWHPGRPWRCSSQRARISFGFGSDWPKLACARPL
                     CPPLYAEDPCCTASAAAVRVRSCWPQLGLPTLVEFLESLEPDLPALRAMGLHLWATGP
                     ETNVAGISNLLSEAADQVDEPVPGYLSAPQNIMDTCLYIFTSGTTGLPKAARISHLKV
                     LQCQGFYHLCGVHQEDVIYLALPLYHMSGSLLGIVGCLGIGATVVLKPKFSASQFWDD
                     CQKHRVTVFQYIGELCRYLVNQPPSKAECDHKVRLAVGSGLRPDTWERFLRRFGPLQI
                     LETYGMTEGNVATFNYTGRQGAVGRASWLYKHIFPFSLIRYDVMTGEPIRNAQGHCMT
                     TSPGEPGLLVAPVSQQSPFLGYAGAPELAKDKLLKDVFWSGDVFFNTGDLLVCDEQGF
                     LHFHDRTGDTFRWKGENVATTEVAEVLETLDFLQEVNIYGVTVPGHEGRAGMAALALR
                     PPQALNLVQLYSHVSENLPPYARPRFLRLQESLATTETFKQQKVRMANEGFDPSVLSD
                     PLYVLDQDIGAYLPLTPARYSALLSGDLRI"
     exon            799..1030
                     /gene="Slc27a3"
                     /gene_synonym="Acsvl3; FATP-3; FATP3; Vlcs-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1189
                     /gene="Slc27a3"
                     /gene_synonym="Acsvl3; FATP-3; FATP3; Vlcs-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..1314
                     /gene="Slc27a3"
                     /gene_synonym="Acsvl3; FATP-3; FATP3; Vlcs-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1315..1509
                     /gene="Slc27a3"
                     /gene_synonym="Acsvl3; FATP-3; FATP3; Vlcs-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1510..1600
                     /gene="Slc27a3"
                     /gene_synonym="Acsvl3; FATP-3; FATP3; Vlcs-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1601..1799
                     /gene="Slc27a3"
                     /gene_synonym="Acsvl3; FATP-3; FATP3; Vlcs-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1800..1897
                     /gene="Slc27a3"
                     /gene_synonym="Acsvl3; FATP-3; FATP3; Vlcs-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1898..2028
                     /gene="Slc27a3"
                     /gene_synonym="Acsvl3; FATP-3; FATP3; Vlcs-3"
                     /inference="alignment:Splign:2.1.0"
     exon            2029..2323
                     /gene="Slc27a3"
                     /gene_synonym="Acsvl3; FATP-3; FATP3; Vlcs-3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2305..2310
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc27a3"
                     /gene_synonym="Acsvl3; FATP-3; FATP3; Vlcs-3"
                     /note="hexamer: AATAAA"
     polyA_site      2323
                     /gene="Slc27a3"
                     /gene_synonym="Acsvl3; FATP-3; FATP3; Vlcs-3"
                     /note="major polyA site"
ORIGIN      
        1 actcctggct cccgcgccac accgcagaag ctgggtggga agggcgggtg ccagcgcacg
       61 cgcgccacgt tcccgggaag aaaggttgtc cgagccggac caaagctggc ttagtgtttc
      121 aggaaggacc acctggagtg tgtgtgagct gctgggacgg actagaggaa aagggcacca
      181 tggcggccct cctgctgctg ctgcccttac tcttgctcct gcctctgctg ctgaagctag
      241 acgtctggcc tcagctgcgc tggctgccgg ccgacctggc cttcacagtt cgcgccctcc
      301 gctgcaaaag ggcccttcga gcacgcgcgc tggccgcagc ggccgccgac cccgaaagct
      361 ctgagagcgg gtgcagtctg gcctggcgtc tcgcgtacct ggcccgggag cagccgacac
      421 acaccttcct catccacggc gcgcagcgct ttagctacgc ggaggctgag cgcgagagca
      481 accggattgc tcgcgccttt ctgcgcgcac ggggctggac cgggggccgc cgaggctcgg
      541 gcaggggcag cactgaggaa ggcgcacgcg tggcgcctcc ggctggagat gcggctgcta
      601 gagggacgac cgcgccccct ctggcacccg gggcgaccgt ggcgctgctc ctcccagcgg
      661 gcccggattt cctttggatt tggttcggac tggccaaagc tggcctgcgc acggcctttg
      721 tgcccaccgc tttacgccga ggacccctgc tgcactgcct ccgcagctgc ggtgcgagtg
      781 cgctcgtgct ggccacagct gggtttgcct acccttgtag agttcctgga gtccctggag
      841 ccggacctgc cggccttgag agccatgggg ctccacctat gggcgacggg ccctgaaact
      901 aatgtagctg gaatcagcaa tttgctatcg gaagcagcag accaagtgga tgagccagtg
      961 ccggggtacc tctctgcccc ccagaacata atggacacct gcctgtacat cttcacctct
     1021 ggcactactg gcctgcccaa ggctgctcga atcagtcatc tgaaggttct acagtgccag
     1081 ggattctacc atctgtgtgg agtccaccag gaggacgtga tctacctcgc actcccactg
     1141 taccacatgt ctggctccct tctgggcatt gtgggctgct tgggcattgg ggccaccgtg
     1201 gtgctgaaac ccaagttctc agctagccag ttctgggacg attgccagaa acacagggtg
     1261 acagtgttcc agtacattgg ggagttgtgc cgatacctcg tcaaccagcc cccgagcaag
     1321 gcagagtgtg accataaggt gcgcttggca gtgggcagtg ggttgcgccc agacacctgg
     1381 gagcgtttcc tgcggcgatt tggacctctg cagatactgg agacgtatgg catgacagag
     1441 ggcaacgtag ctacgttcaa ttacacagga cggcagggtg cagtggggcg agcttcctgg
     1501 ctttacaagc acatcttccc cttctccttg attcgatacg atgtcatgac aggggagcct
     1561 attcggaatg cccaggggca ctgcatgacc acatctccag gtgagccagg cctactggtg
     1621 gccccagtga gccagcagtc ccccttcctg ggctatgctg gggctccgga gctggccaag
     1681 gacaagctgc tgaaggatgt cttctggtct ggggacgttt tcttcaatac tggggacctc
     1741 ttggtctgtg atgagcaagg ctttcttcac ttccacgatc gtactggaga caccttcagg
     1801 tggaagggag agaatgtggc cacaactgaa gtggctgagg tcttggagac cctggacttc
     1861 cttcaggagg tgaacatcta tggagtcacg gtgccagggc acgaaggcag ggcaggcatg
     1921 gcggccttgg ctctgcggcc cccgcaggct ctgaacctgg tgcagctcta cagccatgtt
     1981 tctgagaact tgccaccgta tgcccgacct cggtttctca ggctccagga atctttggcc
     2041 actactgaga ccttcaaaca gcagaaggtt aggatggcca atgagggctt tgaccccagt
     2101 gtactgtctg acccactcta tgttctggac caagatatag gggcctacct gcccctcaca
     2161 cctgcccggt acagtgccct cctgtctgga gaccttcgaa tctgaaacct tccacttgag
     2221 ggaggggctc ggagggtaca ggccaccatg gctgcaccag ggagggtttt cgggtatctt
     2281 ttgtatatgg agtcattatt ttgtaataaa cagctggagc tta
//
