LOCUS       NM_178743               2692 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus solute carrier family 26, member 11 (Slc26a11), mRNA.
ACCESSION   NM_178743 XM_993939
VERSION     NM_178743.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2692)
  AUTHORS   Rahmati,N., Vinueza Veloz,M.F., Xu,J., Barone,S., Rodolfo Ben
            Hamida,N., Schonewille,M., Hoebeek,F.E., Soleimani,M. and De
            Zeeuw,C.I.
  TITLE     SLC26A11 (KBAT) in Purkinje Cells Is Critical for Inhibitory
            Transmission and Contributes to Locomotor Coordination
  JOURNAL   eNeuro 3 (3) (2016)
   PUBMED   27390771
  REMARK    GeneRIF: Study examined at both the cellular and systems
            physiological level the function of a recently discovered chloride
            channel, SLC26A11 or kidney brain anion transporter (KBAT) in
            Purkinje cells; findings support an important role for SLC26A11 in
            moderating chloride homeostasis and neuronal activity in the
            cerebellum.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2692)
  AUTHORS   Lewandowski,J.P., Du,F., Zhang,S., Powell,M.B., Falkenstein,K.N.,
            Ji,H. and Vokes,S.A.
  TITLE     Spatiotemporal regulation of GLI target genes in the mammalian limb
            bud
  JOURNAL   Dev Biol 406 (1), 92-103 (2015)
   PUBMED   26238476
REFERENCE   3  (bases 1 to 2692)
  AUTHORS   Rahmati,N., Kunzelmann,K., Xu,J., Barone,S., Sirianant,L., De
            Zeeuw,C.I. and Soleimani,M.
  TITLE     Slc26a11 is prominently expressed in the brain and functions as a
            chloride channel: expression in Purkinje cells and stimulation of V
            H-ATPase
  JOURNAL   Pflugers Arch 465 (11), 1583-1597 (2013)
   PUBMED   23733100
REFERENCE   4  (bases 1 to 2692)
  AUTHORS   Dawson,P.A., Rakoczy,J. and Simmons,D.G.
  TITLE     Placental, renal, and ileal sulfate transporter gene expression in
            mouse gestation
  JOURNAL   Biol Reprod 87 (2), 43 (2012)
   PUBMED   22674389
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2692)
  AUTHORS   Xu,J., Barone,S., Li,H., Holiday,S., Zahedi,K. and Soleimani,M.
  TITLE     Slc26a11, a chloride transporter, localizes with the vacuolar
            H(+)-ATPase of A-intercalated cells of the kidney
  JOURNAL   Kidney Int 80 (9), 926-937 (2011)
   PUBMED   21716257
  REMARK    GeneRIF: Slc26a11 is a partner of vacuolar H(+)-ATPase facilitating
            acid secretion in the collecting duct.
REFERENCE   6  (bases 1 to 2692)
  AUTHORS   Willnow,T., Antignac,C., Brandli,A., Christensen,E., Cox,R.,
            Davidson,D., Davies,J., Devuyst,O., Eichele,G., Hastie,N.,
            Verroust,P., Schedl,A. and Meij,I.
  TITLE     The European renal genome project: an integrated approach towards
            understanding the genetics of kidney development and disease
  JOURNAL   Organogenesis 2 (2), 42-47 (2005)
   PUBMED   19521566
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF345196.1, AK052202.1 and AL645911.14.
            
            On or before May 4, 2006 this sequence version replaced
            XM_993939.1, NM_178743.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF345196.1, AK089182.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-734               AF345196.1         1-734
            735-2426            AK052202.1         822-2513
            2427-2692           AL645911.14        87746-88011
FEATURES             Location/Qualifiers
     source          1..2692
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 83.36 cM"
     gene            1..2692
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /note="solute carrier family 26, member 11"
                     /db_xref="GeneID:268512"
                     /db_xref="MGI:MGI:2444589"
     exon            1..79
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     exon            80..305
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..1904
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /note="anion exchanger Slc26a11; novel sulfate transporter
                     protein (Slc26a11); kidney brain anion transporter"
                     /codon_start=1
                     /product="sodium-independent sulfate anion transporter"
                     /protein_id="NP_848858.2"
                     /db_xref="CCDS:CCDS25717.1"
                     /db_xref="GeneID:268512"
                     /db_xref="MGI:MGI:2444589"
                     /translation="MAPDTCCCSATALRRRLPVLAWVPDYSLQWLRLDFIAGLSVGLT
                     VIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFRE
                     PAYAVLLAFLSGCIQLAMGLLHLGFLLDFISCPVIKGFTSAASITIGFGQIKNLLGLQ
                     KIPRQFFLQVYHTFLHIGETRVGDAVLGLASMLLLLVLKCMREHMPPPHPEMPLAVKF
                     SRGLVWTVTTARNALVVSSAALIAYAFEVTGSHPFVLTGKIAEGLPPVRIPPFSVTRD
                     NKTISFSEMVQDMGAGLAVVPLMGLLESIAVAKSFASQNNYRIDANQELLAIGLTNVL
                     GSLVSSYPVTGSFGRTAVNAQTGVCTPAGGLVTGALVLLSLNYLTSLFSYIPKSALAA
                     VIITAVTPLFDVKIFRSLWRVQRLDLLPLCVTFLLSFWEIQYGILAGSLVSLLILLHS
                     VARPKTQVSEGQIFVLQPASGLYFPAIDALREAITNRALEASPPRSAVLECTHISSVD
                     YTVIVGLGELLEDFQKKGVALAFVGLQVPVLRTLLAADLKGFRYFTTLEEAEKFLQQE
                     PGTEPNSIHEDAVPEQRSSLLKSPSGP"
     exon            306..498
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     exon            499..584
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     exon            585..664
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     exon            665..807
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     exon            808..983
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1056
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     exon            1057..1107
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     exon            1108..1168
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1224
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     exon            1225..1365
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1493
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     exon            1494..1593
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     exon            1594..1727
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     exon            1728..1800
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     exon            1801..2692
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2616..2621
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /note="hexamer: ATTAAA"
     regulatory      2646..2651
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /note="hexamer: AATACA"
     polyA_site      2647
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
                     /note="major polyA site"
     polyA_site      2667
                     /gene="Slc26a11"
                     /gene_synonym="F630021I08Rik; KBAT"
ORIGIN      
        1 atgtcctgcc cactctgttt ctgagattcc tgcggactca gctaccgcca cttcggaaga
       61 ccctgagtct cagcgtccgc tctgtgaaag gtctgggtca gaccagatcc cccagcctgc
      121 acatggcacc agacacatgc tgctgctctg ctacggccct gaggaggagg ctacccgtcc
      181 tggcctgggt gcctgactac tctctgcagt ggctgaggct ggacttcatc gctggacttt
      241 ccgtgggact caccgtcatt ccccaggccc tggcctatgc agaagtggct ggactcccac
      301 cccagtacgg cctctactct gccttcatgg gatgcttcgt gtatttcttc ctgggcacct
      361 cccgggatgt gactctgggc cccacggcta tcatgtctct cctggtgtcc ttctacacct
      421 tccgtgagcc tgcctatgct gtgctgcttg ccttcctgtc tgggtgtatc cagctggcca
      481 tggggctcct gcatttgggg ttcctgctgg acttcatctc ctgccctgtc attaaaggct
      541 tcacctccgc tgccagcatc acaattggct ttggacagat caagaacctg ctgggattgc
      601 agaaaatccc ccggcagttc ttcctccagg tgtaccacac cttcctccac atcggagaga
      661 ccagggtagg cgacgctgtc ctcggactgg cctccatgtt gctgctgctt gtgctgaagt
      721 gtatgcggga acacatgcct cctccccatc ctgagatgcc ccttgccgtg aagttcagcc
      781 gtgggctggt gtggactgtc acaacagctc gcaatgccct ggtggtctcc tccgcggctc
      841 tgattgctta cgccttcgag gtgacaggat cccatccctt tgttctgact ggaaagatcg
      901 ccgaggggct ccctccggtg cggatcccac ccttctcagt gaccagggac aataagacca
      961 tctcgttctc tgagatggtg caggacatgg gggccggact ggctgtggta cctctgatgg
     1021 ggctcctgga gagcattgcc gtggccaaat ccttcgcgtc tcagaataac taccgcattg
     1081 atgctaacca ggaactactg gccattggcc tcaccaatgt gctgggctcc ctcgtctcct
     1141 cttacccagt cactggcagc tttgggcgga cagctgtgaa tgcccagaca ggggtgtgta
     1201 ccccggcagg aggcctggtg actggtgccc tggtgctgct gtccctgaac tacttgacct
     1261 cactcttctc ctatatcccc aagtctgccc tggctgccgt gatcatcacg gctgtgaccc
     1321 cactctttga tgtcaagatc ttcaggagtc tctggcgcgt tcagaggctg gatctgctac
     1381 cactgtgtgt gacgttcctg ctgtccttct gggagatcca gtacggtatc ctggccggta
     1441 gcctggtgtc tttgctcatt ctcctgcact cggtagctag gcccaagact caggtgtcag
     1501 aaggacaaat ttttgttctt cagccggcca gcggcctgta cttccctgca attgatgccc
     1561 tccgagaggc aataacgaac cgggcactgg aagcatcccc accacgttcc gcggttctgg
     1621 agtgcacgca tatcagcagt gtagactaca ccgtgatcgt gggactcggt gagctcctgg
     1681 aggacttcca gaagaaagga gtcgccctgg cctttgttgg cctacaggtg cccgtgctcc
     1741 gcacactgtt ggccgctgac ctcaaggggt tccgttactt caccactctg gaggaggctg
     1801 agaaattcct gcagcaggaa ccaggaactg agcccaacag catccatgaa gatgctgttc
     1861 cagagcaaag gagctccctg ctcaagtctc cctccggccc ctgaagagca gatggtatag
     1921 gaagggtttc tggaaggttc tgtcaccatg acttggagtc acctgataga ctcaccaacc
     1981 tggtgggact taaaaggcac tgcataggtg gctctgggga acagcaggga gccatgtatg
     2041 atttccaggg tgtcactttc ctgctgtccc ctaggtgtga gtatttgagg gctgggctga
     2101 ctgaaaagtc tttcagagag agagagagag agacagagac ccagagacac acacatggct
     2161 tctggcctgg tctggcaggg taaggtgaca ctctccagat cccagattct tctttggaat
     2221 caggtcctac tggagaaaaa tcaaagagat tgggcatctc ggagatgtgt ctgaccatgt
     2281 catgaagtct aatctgagct gaagaggtgg ccacagcatg ccacacaagg tcaattctgt
     2341 ttaaaatcat gtgtttttta aatggaagtc actctggtgt ttttgtaaag caaaacaaaa
     2401 acatttatgc ttactttaaa aaaaaaatcc aagaactcat gcatcctgtt cactattctc
     2461 ttaactgagg tcccctgccc ggacaggtgt gtatccgtca gtgtgtgcac acggtgccgt
     2521 ctgatgtgaa gacccgaatc actgtattaa ggtgctttgt aaactgtctt catgcagtca
     2581 ttaattgtga attatttatt gtgatgatca atgacattaa atgcaagatt tatttacctt
     2641 attaaaatac aagatttatt tattgtatta aaatacaata ttctgtgggt cc
//
