LOCUS       NM_001009949            4438 bp    mRNA    linear   ROD 04-MAR-2025
DEFINITION  Mus musculus solute carrier family 25, member 51 (Slc25a51), mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_001009949 XM_006537834 XM_131400
VERSION     NM_001009949.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4438)
  AUTHORS   Fu,Z., Kim,H., Morse,P.T., Lu,M.J., Huttemann,M., Cambronne,X.A.,
            Zhang,K. and Zhang,R.
  TITLE     The mitochondrial NAD+ transporter SLC25A51 is a fasting-induced
            gene affecting SIRT3 functions
  JOURNAL   Metabolism 135, 155275 (2022)
   PUBMED   35932995
  REMARK    GeneRIF: The mitochondrial NAD(+) transporter SLC25A51 is a
            fasting-induced gene affecting SIRT3 functions.
            GeneRIF: The mitochondrial NAD+ transporter SLC25A51 is a
            fasting-induced gene affecting SIRT3 functions in the liver.
REFERENCE   2  (bases 1 to 4438)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4438)
  AUTHORS   Luongo,T.S., Eller,J.M., Lu,M.J., Niere,M., Raith,F., Perry,C.,
            Bornstein,M.R., Oliphint,P., Wang,L., McReynolds,M.R., Migaud,M.E.,
            Rabinowitz,J.D., Johnson,F.B., Johnsson,K., Ziegler,M.,
            Cambronne,X.A. and Baur,J.A.
  TITLE     SLC25A51 is a mammalian mitochondrial NAD+ transporter
  JOURNAL   Nature 588 (7836), 174-179 (2020)
   PUBMED   32906142
  REMARK    GeneRIF: SLC25A51 is a mammalian mitochondrial NAD(+) transporter.
REFERENCE   4  (bases 1 to 4438)
  AUTHORS   Najas,S., Pijuan,I., Esteve-Codina,A., Usieto,S., Martinez,J.D.,
            Zwijsen,A., Arbones,M.L., Marti,E. and Le Dreau,G.
  TITLE     A SMAD1/5-YAP signalling module drives radial glia
            self-amplification and growth of the developing cerebral cortex
  JOURNAL   Development 147 (13) (2020)
   PUBMED   32541003
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4438)
  AUTHORS   Kasowitz,S.D., Ma,J., Anderson,S.J., Leu,N.A., Xu,Y., Gregory,B.D.,
            Schultz,R.M. and Wang,P.J.
  TITLE     Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and
            splicing during mouse oocyte development
  JOURNAL   PLoS Genet 14 (5), e1007412 (2018)
   PUBMED   29799838
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4438)
  AUTHORS   Pan,J., Mor,G., Ju,W., Zhong,J., Luo,X., Aldo,P.B., Zhong,M.,
            Yu,Y., Jenkins,E.C., Brown,W.T. and Zhong,N.
  TITLE     Viral Infection-Induced Differential Expression of LncRNAs
            Associated with Collagen in Mouse Placentas and Amniotic Sacs
  JOURNAL   Am J Reprod Immunol 74 (3), 237-257 (2015)
   PUBMED   26073538
REFERENCE   7  (bases 1 to 4438)
  AUTHORS   Nakahara,M., Tateyama,H., Araki,M., Nakagata,N., Yamamura,K. and
            Araki,K.
  TITLE     Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from
            MSM/Ms mice
  JOURNAL   Mamm Genome 24 (5-6), 228-239 (2013)
   PUBMED   23604909
REFERENCE   8  (bases 1 to 4438)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
REFERENCE   9  (bases 1 to 4438)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   10 (bases 1 to 4438)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL772376.6, AK165253.1, BC089000.1 and AW049773.1.
            
            On or before Mar 13, 2014 this sequence version replaced
            XM_006537834.1, NM_001009949.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK146788.1, AK156342.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG   :: upstream AUG and CDS
                                                  extension is not conserved
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5                 AL772376.6         53974-53978         c
            6-1357              AK165253.1         2-1353
            1358-4295           BC089000.1         1253-4190
            4296-4433           AW049773.1         20-157              c
            4434-4438           AL772376.6         41135-41139         c
FEATURES             Location/Qualifiers
     source          1..4438
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 23.96 cM"
     gene            1..4438
                     /gene="Slc25a51"
                     /gene_synonym="9130208E07Rik; D130005A03Rik; Gm138;
                     Mcart1"
                     /note="solute carrier family 25, member 51"
                     /db_xref="GeneID:230125"
                     /db_xref="MGI:MGI:2684984"
     exon            1..72
                     /gene="Slc25a51"
                     /gene_synonym="9130208E07Rik; D130005A03Rik; Gm138;
                     Mcart1"
                     /inference="alignment:Splign:2.1.0"
     exon            73..181
                     /gene="Slc25a51"
                     /gene_synonym="9130208E07Rik; D130005A03Rik; Gm138;
                     Mcart1"
                     /inference="alignment:Splign:2.1.0"
     exon            182..4438
                     /gene="Slc25a51"
                     /gene_synonym="9130208E07Rik; D130005A03Rik; Gm138;
                     Mcart1"
                     /inference="alignment:Splign:2.1.0"
     CDS             224..1120
                     /gene="Slc25a51"
                     /gene_synonym="9130208E07Rik; D130005A03Rik; Gm138;
                     Mcart1"
                     /note="mitochondrial carrier triple repeat protein 1;
                     mitochondrial carrier triple repeat 1; mitochondrial
                     NAD(+) transporter SLC25A51"
                     /codon_start=1
                     /product="mitochondrial nicotinamide adenine dinucleotide
                     transporter SLC25A51"
                     /protein_id="NP_001009949.3"
                     /db_xref="CCDS:CCDS18137.1"
                     /db_xref="GeneID:230125"
                     /db_xref="MGI:MGI:2684984"
                     /translation="MMDSEAHEKRPPMLTSSNQDLSPHIAGVGDMKHYLCGYCAAFNN
                     VAITYPVQKILFRQQLYGIKTRDAVLQLRKDGFRNLYRGILPPLMQKTTTLALMFGLY
                     EDLSRLLHKHVSSAPEFATRSVAALLAGTTEAILTPFERVQTLLQDHKHHDKFTNTYQ
                     AFRALRCHGIAEYYRGMVPILFRNGFGNVLFFGLRGPIKESLPTATTYSAHLVNDFIC
                     GGVLGAVLGFLSFPINVVKARIQSQIGGPFLSLPMVFKTIWIERDRKLINLFRGAHLN
                     YHRSLISWGIINATYEFLLKIV"
     regulatory      4274..4279
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc25a51"
                     /gene_synonym="9130208E07Rik; D130005A03Rik; Gm138;
                     Mcart1"
                     /note="hexamer: AATAAA"
     polyA_site      4298
                     /gene="Slc25a51"
                     /gene_synonym="9130208E07Rik; D130005A03Rik; Gm138;
                     Mcart1"
                     /note="major polyA site"
     regulatory      4417..4422
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc25a51"
                     /gene_synonym="9130208E07Rik; D130005A03Rik; Gm138;
                     Mcart1"
                     /note="hexamer: ATTAAA"
     polyA_site      4438
                     /gene="Slc25a51"
                     /gene_synonym="9130208E07Rik; D130005A03Rik; Gm138;
                     Mcart1"
                     /note="major polyA site"
ORIGIN      
        1 ggaccagtct gcgcctgcgc gggcgcgggc tcgctcgcca gccgtcctgc gggcttgcgc
       61 cccgggccgt gggaaatgca gttatcaaaa ctggcttcag aagagagaag gctaacaatg
      121 gacaacactg ggaaagttcc cagaaagctg tcatcctcag tgccaggctc agatgtcaca
      181 ggttaaagaa actcttcccc agagaggaaa ggccggaagc accatgatgg actccgaagc
      241 acatgagaag aggcccccaa tgttgacctc ttcgaaccag gacttgtcac ctcacattgc
      301 gggcgtggga gacatgaaac attacttgtg tggctactgc gcggccttca acaacgtggc
      361 gatcacttac ccggttcaga agatcctctt ccggcagcag ctttacggca tcaagacccg
      421 ggatgcagtc ctgcagctga ggaaggatgg gttccgcaac ttgtaccgcg gaatcctgcc
      481 cccgctgatg cagaagacga ccacgctggc acttatgttt ggtctgtatg aggacctgtc
      541 gcgcctgctc cacaagcacg tgagcagcgc tcccgagttt gccacccgta gcgtggcggc
      601 gctgctggcc gggacgacgg aagccattct cactccattc gaaagggttc agactttgct
      661 tcaggaccac aaacatcacg ataagttcac aaacacttac caggccttca gggcgctcag
      721 atgccatggg attgcagagt attaccgagg catggtgccc atccttttcc ggaatgggtt
      781 cggcaatgtc cttttttttg gccttcgagg gcccattaag gagagcctgc ctactgccac
      841 tacatacagc gcccacctgg tcaacgactt catctgtgga ggtgtactcg gggccgtgct
      901 gggcttctta agcttcccca ttaacgttgt caaagctcga atacagtctc agattggcgg
      961 gccattcctg tctctcccca tggtcttcaa gactatctgg atagagcggg acaggaagct
     1021 gatcaatctc ttcagaggtg cacatctgaa ttaccaccgc tctctcatct cctggggaat
     1081 aatcaatgcc acttacgagt ttttgttaaa gattgtatga tgaaatcatt atgtgagatg
     1141 ttattctcat ctaactagac ctaaggaaaa tgcaatttgg ctttgttcct aattggctta
     1201 agtacagttt ggtgtccaag accaagccat aacttgcaga cagagcactg acaagaacag
     1261 agtccaggtt tcagtgggca ggtgtcaggg ttcgggtgtg gtcattactc cagagcttta
     1321 ggctgctgtt gcccgggaac cagcctgcac cgctgggctg tggcctccgc agccagagcg
     1381 cgtgcttcgc ccccagcccg gggcatctca ggctcattct cacctcattt actttgtctc
     1441 tgctcttaag agggccataa tcattagacc ccagctctgc acggaggact ggagcagagg
     1501 tgccactcag tgccatgcct gagctccatg atgaatggtt ggggttagct ttgaaataag
     1561 tgctgttgag atagccgcga tctaaacttt ctgttcacat ttgatagagt tgagcagcta
     1621 atgaacgctt ccattttgct gtttggcttt gaacactttc tgtttaattc tgagtctgac
     1681 tttaagccct tccagaatgt ccttgtgctg tttttactga attcattgcc aaaagatagg
     1741 gtgccctagt taaattccgt tgtgtgcttc atcgtggtaa gctggtcact gcaggctctg
     1801 ctattctgct tgcttctttg tgctactgct gtcgacagcc aaccagtgag gacactgtcc
     1861 cttgtgaata gtaactgtca tgtctgtcct gctctctggt actggacttt aaacaaataa
     1921 acacttccat aaagttttat ttcaggggtt ttaatgcaac cccaagtctt ctttttttct
     1981 ggtttctcag tgctacagag tgagctaagg agtggagggt gcttcccctc tggccgcccg
     2041 tctctttctc tgggaagaaa gatttcaggg ttctgctact caggagccca gttgccactg
     2101 tgccgtttag gaatgtctgc tctaagtagc agccctgact tctggtcagg taggatccaa
     2161 ctggcaggaa ccaggccaag gagtcacata gctattttct gggtaaatgc tgtaatggaa
     2221 ataccatcag tctgggaagt agcttagaat tttcaggaag ctgtctgtga ccaccaccgg
     2281 tcagcttggt tcccaggagt cgacataagc aagtcagttt ctttgctttt tttttttttg
     2341 tttgtttgtt tattttttta aatggtgcta gggattgaac ccagggcctt gcacatccta
     2401 ggcaaatgct gtcccactac actccagcct tcccagtttt ggttttattt ggttttattt
     2461 tattttgaga cagattctca acaggtagcc caggctcgtc ttgaactctc ctggctctgc
     2521 cttctgagtg ttgggattaa aggcgtgagc tgccggacct ggcatcccca gtccttaaga
     2581 ataggttcct tcctccctcc ctccctccct ccctccctcc cttccttcct tccttccttt
     2641 ctttccagag ctgaggacct aacccagggc cttgcacttg ctaggcaaga gctctaccac
     2701 tgagctaagt ccccaacccc aaagataggt ttcttactaa gtttttcatt gggtaattgc
     2761 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtacac ctatgtacct ataaactgaa
     2821 atcagaccct cagctgcagt ttgagagaag tttctgggga aggtaatcca aaacagctct
     2881 ttaactacac tgaagctggt tacataaagc taccatcatc cagctgtaac agttgggagc
     2941 ctggtaagca ttggggtggc agtaacggag gtcagcggct ttggagcgac actggtggaa
     3001 gtgcagtgcg gacattaagg ggcaaatgtg aggactcggc agacaagaat ttgtctgaga
     3061 tacatctgag tactactgtc ttcagttaca atttgaaggt gagaagtctc agaaacgaga
     3121 gatggcgcct tgggtcctga cccctgtgtc cacgtgcagc attgcccaga tgcagcacag
     3181 gggaggggag ttaaccaggg attatacttt aatttttgtt tgtttttgtt ttttcgagac
     3241 aaggtttctc tgtgtagccc tggctgtcct ggaactcact ctgtagacca ggctggcctt
     3301 gaactcagaa atccacctgc ctctgcctcc cgagtgctgg gattaaaggc gtgcgccacc
     3361 actgcccagc ccaggattat acttggcctt gttttcttta cactccgtgc aggtggcgca
     3421 agtgtcggct gtaaagcgct cctttgaggg tcaccaggct gttaagggca aggctttggc
     3481 tttgctgact taattatgtg acattttaaa gcaagattaa acttcctaat gctttttaac
     3541 ttttaaacac tttgtcaccc ttagagctct taaagactag attgcagtgt attacagagg
     3601 tggctctgtc tctgataaat ttaagtttga caaaaataaa atcagagctt gtaatccact
     3661 ttgaacttct atgtcagaat gtaattaata gtcttaacta gtgcggtgat attttttaaa
     3721 ggcaaaaaag actaaagaac tctgaaaagc tttaaagtgg cctttgtgtt acatgtgtgg
     3781 cacaggtggc tcatgagtgc aggacacgag tgtcccgtgt gtcctgtctg atgccactag
     3841 aaacctacga gttttgcatt taacacacca gtgctgtaaa ccctcaggac ggtagcaggg
     3901 tcaacacagc ctttgcattg tggcaaattg gggttttgct tcctttgtgg ttagagacag
     3961 atgtttgtgc ctatcaacgt ttatcttgtg gttggtcata taatcacttg ctatatattg
     4021 tgaccctgtg caatgaagca gaattgtaca tacatagtat tatttgagta cctgaaattc
     4081 ctaagctcaa agacaatata gataaacttg taaggtttag agggctggcc tcgtgtaagt
     4141 ggttaataga gagtgaaccc tggtttgagg gtggtgagag ctgggtggat gtggtcaccg
     4201 ctgggccaga ctgttgccag gaaggcattc atgcttgggt tccttatgtc aaatgtattt
     4261 tttctcctat ataaataaat gcatatcaaa agcttgaata tgttctctct agatttaaag
     4321 atttttttac ttttttatgc tctttgtata aacttaatgc tctttgcttg ccaaactgct
     4381 gaggaggtgg gtctgcatat atttcttctt ttcgttatta aaagtagcta aacacaaa
//
