LOCUS       NM_007451               1317 bp    mRNA    linear   ROD 24-DEC-2024
DEFINITION  Mus musculus solute carrier family 25 (mitochondrial carrier,
            adenine nucleotide translocator), member 5 (Slc25a5), mRNA.
ACCESSION   NM_007451
VERSION     NM_007451.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1317)
  AUTHORS   Zhou,B., Feng,C., Sun,S., Chen,X., Zhuansun,D., Wang,D., Yu,X.,
            Meng,X., Xiao,J., Wu,L., Wang,J., Wang,J., Chen,K., Li,Z., You,J.,
            Mao,H., Yang,S., Zhang,J., Jiao,C., Li,Z., Yu,D., Wu,X., Zhu,T.,
            Yang,J., Xiang,L., Liu,J., Chai,T., Shen,J., Mao,C.X., Hu,J.,
            Hao,X., Xiong,B., Zheng,S., Liu,Z. and Feng,J.
  TITLE     Identification of signaling pathways that specify a subset of
            migrating enteric neural crest cells at the wavefront in mouse
            embryos
  JOURNAL   Dev Cell 59 (13), 1689-1706 (2024)
   PUBMED   38636517
REFERENCE   2  (bases 1 to 1317)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 1317)
  AUTHORS   Bround,M.J., Havens,J.R., York,A.J., Sargent,M.A., Karch,J. and
            Molkentin,J.D.
  TITLE     ANT-dependent MPTP underlies necrotic myofiber death in muscular
            dystrophy
  JOURNAL   Sci Adv 9 (34), eadi2767 (2023)
   PUBMED   37624892
REFERENCE   4  (bases 1 to 1317)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1317)
  AUTHORS   Saragovi,A., Abramovich,I., Omar,I., Arbib,E., Toker,O.,
            Gottlieb,E. and Berger,M.
  TITLE     Systemic hypoxia inhibits T cell response by limiting
            mitobiogenesis via matrix substrate-level phosphorylation arrest
  JOURNAL   Elife 9, e56612 (2020)
   PUBMED   33226340
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1317)
  AUTHORS   Levy,S.E., Chen,Y.S., Graham,B.H. and Wallace,D.C.
  TITLE     Expression and sequence analysis of the mouse adenine nucleotide
            translocase 1 and 2 genes
  JOURNAL   Gene 254 (1-2), 57-66 (2000)
   PUBMED   10974536
REFERENCE   7  (bases 1 to 1317)
  AUTHORS   Sutton,K.A. and Wilkinson,M.F.
  TITLE     The rapidly evolving Pem homeobox gene and Agtr2, Ant2, and Lamp2
            are closely linked in the proximal region of the mouse X chromosome
  JOURNAL   Genomics 45 (2), 447-450 (1997)
   PUBMED   9344676
REFERENCE   8  (bases 1 to 1317)
  AUTHORS   Ellison,J.W., Salido,E.C. and Shapiro,L.J.
  TITLE     Genetic mapping of the adenine nucleotide translocase-2 gene (Ant2)
            to the mouse proximal X chromosome
  JOURNAL   Genomics 36 (2), 369-371 (1996)
   PUBMED   8812469
REFERENCE   9  (bases 1 to 1317)
  AUTHORS   Ellison,J.W., Li,X., Francke,U. and Shapiro,L.J.
  TITLE     Rapid evolution of human pseudoautosomal genes and their mouse
            homologs
  JOURNAL   Mamm Genome 7 (1), 25-30 (1996)
   PUBMED   8903724
REFERENCE   10 (bases 1 to 1317)
  AUTHORS   Cozens,A.L., Runswick,M.J. and Walker,J.E.
  TITLE     DNA sequences of two expressed nuclear genes for human
            mitochondrial ADP/ATP translocase
  JOURNAL   J Mol Biol 206 (2), 261-280 (1989)
   PUBMED   2541251
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BY280917.1, AK003467.1 and
            BY472909.1.
            
            On May 7, 2015 this sequence version replaced NM_007451.3.
            
            Summary: This gene encodes a transmembrane domain-containing
            protein that localizes to the mitochondrial inner membrane. The
            encoded protein facilitates the exchange of ADP from the cytoplasm
            with ATP from the mitochondria. Pseudogenes for this gene are found
            on multiple chromosomes. [provided by RefSeq, May 2015].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK012751.1, BC004570.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-55                BY280917.1         2-56
            56-1293             AK003467.1         2-1239
            1294-1317           BY472909.1         430-453
FEATURES             Location/Qualifiers
     source          1..1317
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 21.2 cM"
     gene            1..1317
                     /gene="Slc25a5"
                     /gene_synonym="Ant2"
                     /note="solute carrier family 25 (mitochondrial carrier,
                     adenine nucleotide translocator), member 5"
                     /db_xref="GeneID:11740"
                     /db_xref="MGI:MGI:1353496"
     exon            1..245
                     /gene="Slc25a5"
                     /gene_synonym="Ant2"
                     /inference="alignment:Splign:2.1.0"
     exon            246..732
                     /gene="Slc25a5"
                     /gene_synonym="Ant2"
                     /inference="alignment:Splign:2.1.0"
     exon            733..873
                     /gene="Slc25a5"
                     /gene_synonym="Ant2"
                     /inference="alignment:Splign:2.1.0"
     exon            874..1295
                     /gene="Slc25a5"
                     /gene_synonym="Ant2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1275..1280
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc25a5"
                     /gene_synonym="Ant2"
                     /note="hexamer: AATAAA"
     polyA_site      1294
                     /gene="Slc25a5"
                     /gene_synonym="Ant2"
                     /note="major polyA site"
ORIGIN      
        1 ggcagctcac cgcctggctg ccgctatata agtcggccat ttgctttgct ccgccccaga
       61 gcccgggagt caaagccggt tgtcaaccca gccctgtccc gcactcgcct gcctcttctt
      121 tttttgcttt caacatgaca gatgccgctg tgtccttcgc caaggacttc ttggccggtg
      181 gagtggccgc agccatctcc aagacagcgg tagcacccat cgagagggtc aagctgctgc
      241 tgcaggtgca gcatgccagc aagcaaatca cggcagataa gcaatacaag ggcatcatag
      301 actgcgtggt tcgtatcccc aaggaacagg gagtcctgtc cttctggcgt gggaacctgg
      361 ccaatgtcat cagatacttc cccacccagg ctctcaactt tgccttcaaa gataaataca
      421 agcagatctt tctgggtggt gtggacaaga ggacccagtt ctggcgctac tttgcaggga
      481 acctggcatc aggtggtgcc gctggggcta catccttgtg ctttgtgtac cctcttgatt
      541 ttgcccgtac ccgtctagca gctgatgtgg gcaaagctgg agctgaaagg gaattcaaag
      601 gccttggtga ctgcctggtt aagatctaca aatctgatgg gattaagggc ctgtaccaag
      661 gctttaatgt gtcagtacag ggcattatca tctaccgagc tgcctacttt ggtatctatg
      721 acactgcaaa gggaatgctc ccagatccca agaatactca catcttcatc agctggatga
      781 ttgcacagtc tgtcactgct gtcgctggcc tgacttccta tccttttgac acggttcgcc
      841 gtcgtatgat gatgcagtct ggacgcaaag gaactgatat catgtacaca ggcacgcttg
      901 actgctggcg gaagatcgcg cgcgatgaag ggagcaaggc ttttttcaag ggcgcatggt
      961 ccaacgttct cagaggcatg ggtggcgcct ttgtgcttgt cttgtatgat gagatcaaga
     1021 aatacacata attatgtcct aggtgttctc cccgagaaca ggcatgttgt ataatatacc
     1081 atatcttgaa cattctggac agattctctg ggcttgtctg ttttatcagt ggcaactatt
     1141 taccagttga aaagtgggaa gcaataatat tcatctgacc agttttctct taaagccatt
     1201 tccataatga caataatgat gggactcaat tatatttttt atttcagtca ctcctgataa
     1261 taaaaaattg aagaaataaa aatacccaaa accagaaaaa aaaaaaaaaa aaaaaaa
//
