LOCUS       NM_001085497            1243 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus solute carrier family 25, member 43 (Slc25a43),
            transcript variant 1, mRNA.
ACCESSION   NM_001085497 XM_110743 XM_909147
VERSION     NM_001085497.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1243)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1243)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1243)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC147709.1.
            
            On Feb 12, 2013 this sequence version replaced NM_001085497.1.
            
            Transcript Variant: This variant (1) encodes the functional
            protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC147709.1, SRR11927932.2130682.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: PMID: 18614015; reported by
                                                  MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1243              BC147709.1         1-1243
FEATURES             Location/Qualifiers
     source          1..1243
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 21.15 cM"
     gene            1..1243
                     /gene="Slc25a43"
                     /gene_synonym="Gm8"
                     /note="solute carrier family 25, member 43"
                     /db_xref="GeneID:194744"
                     /db_xref="MGI:MGI:2684854"
     exon            1..387
                     /gene="Slc25a43"
                     /gene_synonym="Gm8"
                     /inference="alignment:Splign:2.1.0"
     CDS             113..1138
                     /gene="Slc25a43"
                     /gene_synonym="Gm8"
                     /note="mitochondrial solute carrier protein"
                     /codon_start=1
                     /product="solute carrier family 25 member 43"
                     /protein_id="NP_001078966.1"
                     /db_xref="CCDS:CCDS40925.1"
                     /db_xref="GeneID:194744"
                     /db_xref="MGI:MGI:2684854"
                     /translation="MATWRRDGRLTGSQRLLCAGLAGAFSLSLTAPLELATVLAQVGK
                     VQSHSLGLWATGRRVWLSEGPRALWKGNGVACLRLFPCSMVQLAAYRKFVVLFMDDLG
                     RISQWSSIVTGSLAGMVSTIVTYPTDLIKTRLMVQNVLEPSYRGLIHAFSTIYQQEGF
                     LALYRGVSLTVLGAVPFSAGSLLVYMNLEKVWNGPRDRFSHLQNFANVCVAAAVSQTL
                     SFPFDTVKRKMQAQSPYLPHYGGVDVHFSGAADCFRQIVKTQGVLGLWNGLTANLLKV
                     VPYFGVMFSMFEFCKRIFLYQNGYTLSPLTYKLTPGVDQSLKPQELRELKKFFKRRKL
                     HSKTPPW"
     exon            388..629
                     /gene="Slc25a43"
                     /gene_synonym="Gm8"
                     /inference="alignment:Splign:2.1.0"
     exon            630..802
                     /gene="Slc25a43"
                     /gene_synonym="Gm8"
                     /inference="alignment:Splign:2.1.0"
     exon            803..937
                     /gene="Slc25a43"
                     /gene_synonym="Gm8"
                     /inference="alignment:Splign:2.1.0"
     exon            938..1243
                     /gene="Slc25a43"
                     /gene_synonym="Gm8"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1138..1143
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc25a43"
                     /gene_synonym="Gm8"
                     /note="hexamer: AATAAA"
     polyA_site      1159
                     /gene="Slc25a43"
                     /gene_synonym="Gm8"
                     /note="major polyA site"
ORIGIN      
        1 gttcatctcc caagtccgcc ccacgccggg cggggcctgg ccggactgct ctaactgccc
       61 ccgcgagccc agggcaccag ccacgaggtg gccggcacgg gcctgggtca ggatggctac
      121 gtggagacgg gatggccggt taaccggcag ccagcggctc ctgtgtgcgg ggctggccgg
      181 ggcgttcagc ctcagcctca ccgcgcccct ggagcttgcc actgtgctgg cccaagtcgg
      241 caaggtgcaa agccactccc tggggctgtg ggccaccgga cgccgggtgt ggctgtccga
      301 ggggccaagg gccctgtgga aagggaatgg cgtggcctgc ctgcgcctct tcccctgcag
      361 catggtacag ctggccgcct accgaaagtt cgttgtgcta ttcatggatg acctgggccg
      421 tatttcccag tggagttcca ttgtgactgg aagtctcgca ggcatggttt ccacgattgt
      481 cacataccct acagacctca tcaaaacccg attgatggtg cagaacgtgc tggaaccatc
      541 atacaggggg ctaatccatg ctttttctac tatttatcaa caagaagggt tcctggccct
      601 ttatcgaggg gtatccctca ctgttttagg tgctgttccc ttctctgctg gctcccttct
      661 agtttacatg aacctggaaa aagtctggaa tggaccccgg gaccgctttt ctcacctgca
      721 gaactttgcc aatgtctgtg tggctgctgc tgtgagccag accctctcct ttccctttga
      781 cactgtgaag agaaagatgc aggctcaaag tccttatctt ccccactatg gaggagtaga
      841 tgtccacttc tcaggagcag ctgactgctt ccggcagatc gtgaaaaccc aaggggtact
      901 ggggctctgg aacggactga cggctaactt actaaaggta gttccatatt ttggagttat
      961 gtttagcatg tttgagttct gtaagagaat ttttctttat caaaatggtt acaccctgtc
     1021 cccactgacc tataaactga ccccaggagt ggaccaaagt ttgaagcccc aggaattacg
     1081 ggagctaaag aagttcttca aacgcagaaa actgcactcc aaaacaccac cttggtaaat
     1141 aaagctgact agaactacac tggtagaagt gcagcaatca tagatgaata tggtgacctc
     1201 ttaactgtgc acatcaggag gagggagagg aaatgggagc acg
//
