LOCUS       NM_026542               1678 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus solute carrier family 25, member 39 (Slc25a39), mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_026542
VERSION     NM_026542.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1678)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1678)
  AUTHORS   Wang,Y., Yen,F.S., Zhu,X.G., Timson,R.C., Weber,R., Xing,C.,
            Liu,Y., Allwein,B., Luo,H., Yeh,H.W., Heissel,S., Unlu,G.,
            Gamazon,E.R., Kharas,M.G., Hite,R. and Birsoy,K.
  TITLE     SLC25A39 is necessary for mitochondrial glutathione import in
            mammalian cells
  JOURNAL   Nature 599 (7883), 136-140 (2021)
   PUBMED   34707288
  REMARK    GeneRIF: SLC25A39 is necessary for mitochondrial glutathione import
            in mammalian cells.
REFERENCE   3  (bases 1 to 1678)
  AUTHORS   Nilsson,R., Schultz,I.J., Pierce,E.L., Soltis,K.A.,
            Naranuntarat,A., Ward,D.M., Baughman,J.M., Paradkar,P.N.,
            Kingsley,P.D., Culotta,V.C., Kaplan,J., Palis,J., Paw,B.H. and
            Mootha,V.K.
  TITLE     Discovery of genes essential for heme biosynthesis through
            large-scale gene expression analysis
  JOURNAL   Cell Metab 10 (2), 119-130 (2009)
   PUBMED   19656490
  REMARK    GeneRIF: Required for functional heme biosynthesis in erythroid
            cells. Possibly regulate ALAS2 through iron-sulfur cluster
            biogenesis.
REFERENCE   4  (bases 1 to 1678)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY291748.1, AK161289.1 and BU758028.1.
            
            On Dec 17, 2009 this sequence version replaced NM_026542.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK019396.1, AK161289.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN00849386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-286               BY291748.1         2-287
            287-1495            AK161289.1         279-1487
            1496-1678           BU758028.1         1-183               c
FEATURES             Location/Qualifiers
     source          1..1678
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 66.29 cM"
     gene            1..1678
                     /gene="Slc25a39"
                     /gene_synonym="3010027G13Rik; D11Ertd333e"
                     /note="solute carrier family 25, member 39"
                     /db_xref="GeneID:68066"
                     /db_xref="MGI:MGI:1196386"
     exon            1..128
                     /gene="Slc25a39"
                     /gene_synonym="3010027G13Rik; D11Ertd333e"
                     /inference="alignment:Splign:2.1.0"
     exon            129..228
                     /gene="Slc25a39"
                     /gene_synonym="3010027G13Rik; D11Ertd333e"
                     /inference="alignment:Splign:2.1.0"
     CDS             144..1223
                     /gene="Slc25a39"
                     /gene_synonym="3010027G13Rik; D11Ertd333e"
                     /note="probable mitochondrial glutathione transporter
                     SLC25A39"
                     /codon_start=1
                     /product="mitochondrial glutathione transporter SLC25A39"
                     /protein_id="NP_080818.1"
                     /db_xref="CCDS:CCDS25498.1"
                     /db_xref="GeneID:68066"
                     /db_xref="MGI:MGI:1196386"
                     /translation="MDDQDPGGISPLQQMVASGAGAVVTSLFMTPLDVVKVRLQSQRP
                     SATSELTTPSRFWSLSYTKSSSALQSPGKCLLYCNGVLEPLYLCPNGTRCATWFQDPT
                     RFTGTLDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGQSLTSD
                     LYAPMVAGALARMGTVTVVSPLELVRTKLQAQHVSYRELASSVQAAVTQGGWRSLWLG
                     WGPTALRDVPFSALYWFNYELVKSWLSGLRPKDQTSVGISFVAGGISGMVAATLTLPF
                     DVVKTQRQMSLGAVEAVRVKPPRVDSTWLLLRRIRAESGTRGLFAGFLPRIIKAAPSC
                     AIMISTYEFGKSFFQRLNQEQPLGR"
     exon            229..288
                     /gene="Slc25a39"
                     /gene_synonym="3010027G13Rik; D11Ertd333e"
                     /inference="alignment:Splign:2.1.0"
     exon            289..333
                     /gene="Slc25a39"
                     /gene_synonym="3010027G13Rik; D11Ertd333e"
                     /inference="alignment:Splign:2.1.0"
     exon            334..467
                     /gene="Slc25a39"
                     /gene_synonym="3010027G13Rik; D11Ertd333e"
                     /inference="alignment:Splign:2.1.0"
     exon            468..535
                     /gene="Slc25a39"
                     /gene_synonym="3010027G13Rik; D11Ertd333e"
                     /inference="alignment:Splign:2.1.0"
     exon            536..660
                     /gene="Slc25a39"
                     /gene_synonym="3010027G13Rik; D11Ertd333e"
                     /inference="alignment:Splign:2.1.0"
     exon            661..834
                     /gene="Slc25a39"
                     /gene_synonym="3010027G13Rik; D11Ertd333e"
                     /inference="alignment:Splign:2.1.0"
     exon            835..944
                     /gene="Slc25a39"
                     /gene_synonym="3010027G13Rik; D11Ertd333e"
                     /inference="alignment:Splign:2.1.0"
     exon            945..1026
                     /gene="Slc25a39"
                     /gene_synonym="3010027G13Rik; D11Ertd333e"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1107
                     /gene="Slc25a39"
                     /gene_synonym="3010027G13Rik; D11Ertd333e"
                     /inference="alignment:Splign:2.1.0"
     exon            1108..1674
                     /gene="Slc25a39"
                     /gene_synonym="3010027G13Rik; D11Ertd333e"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1501
                     /gene="Slc25a39"
                     /gene_synonym="3010027G13Rik; D11Ertd333e"
                     /note="major polyA site"
ORIGIN      
        1 ggtctcaccg ctctcccggg cggccgctgt gcgaagcggg cacgcgcgga ccctgcaccg
       61 gccgcggagc cgctatgggc ccgccaggcc cctggcgtgg cgcggcgcaa ggaccggctc
      121 cgagccagga ttgaaattcc aagatggatg atcaggaccc tgggggcatt agcccccttc
      181 agcaaatggt ggcctcagga gccggggctg tggtcacctc cctcttcatg acacccctgg
      241 atgtggtgaa ggtccgcctt cagtctcaga gaccctcggc aaccagcgaa ttgacaactc
      301 cctccagatt ctggagtctc tcctacacca aatcatcctc cgctctacag tccccaggga
      361 agtgcctcct atactgcaat ggagtcctgg agcccctgta cctgtgccca aatggtaccc
      421 gctgtgccac ctggtttcag gaccccacac ggttcactgg caccttggat gcctttgtga
      481 agattgtgcg gcatgagggc actaggaccc tgtggagcgg cctcccagcc accctggtga
      541 tgaccgtgcc agctactgct atctacttca ctgcttacga ccaactcaag gccttcctgt
      601 gtggtcagtc cttgacctct gacctctacg cacccatggt ggctggtgcc ctcgcccgaa
      661 tgggcaccgt gacagttgtc agccccttgg agctcgtgcg gaccaagctg caggctcagc
      721 atgtgtcata ccgtgagctg gcttcctctg ttcaagctgc ggtgactcag ggtggctggc
      781 gctctctgtg gctgggctgg ggtcccacag ctcttcgaga tgtccccttc tcagctctgt
      841 actggttcaa ctacgagttg gtgaagagct ggctgagcgg actgagacca aaagaccaga
      901 catcggtggg catcagcttc gtggccggtg gcatctcagg aatggtggct gccaccctta
      961 ccctaccctt cgatgtggtg aagacacagc gacagatgtc actgggagcg gtggaggctg
     1021 tgagagtgaa gccgcccaga gtggactcca cctggctcct gcttcgcaga atccgggctg
     1081 aatctggcac caggggactc tttgcaggct tcctccccag gatcatcaag gctgcaccct
     1141 cctgtgccat catgatcagc acttacgagt ttggcaaaag cttcttccag aggctcaacc
     1201 aggagcagcc tctgggccgc tgaaagtcgg ggagcaaccg gctcttgcac gggtgggatc
     1261 aggagactga gccaagtgcc ttccctccca gtccagtcac ccaggctgtc ctcagacctg
     1321 gattcctgct gtttcccttc ccaggattgc ccctctcccg cctcccgaat tcaagaccaa
     1381 atctgatgat cgcccttttt tgtatcccca tgtttgttat agcttggccc gaggagcttg
     1441 ggccaggcag tatcttggcc ccattcattc cttgtctaaa gatgatggtc ttctgtgcac
     1501 agctgtggct gtagtgtctt ggggtacgtg tgcacgtttg ggggtcccca gtcagacaca
     1561 gtggcccaca cctgttattc cttcacttgg gaggctgagg caggaggagt gcctccaata
     1621 ccaagccagc caggactaca cagccaaatt ctatcttcac aaaaaaaaaa aaaaaaaa
//
