LOCUS       NM_138756               3061 bp    mRNA    linear   ROD 31-MAY-2024
DEFINITION  Mus musculus solute carrier family 25, member 36 (Slc25a36), mRNA.
ACCESSION   NM_138756
VERSION     NM_138756.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3061)
  AUTHORS   Xin,Y., Wang,Y., Zhong,L., Shi,B., Liang,H. and Han,J.
  TITLE     Slc25a36 modulates pluripotency of mouse embryonic stem cells by
            regulating mitochondrial function and glutathione level
  JOURNAL   Biochem J 476 (11), 1585-1604 (2019)
   PUBMED   31036718
  REMARK    GeneRIF: Cdx2-positive cells emerged in Slc25a36-deficient colonies
            under trophoblast stem cell culture conditions. As a result of
            Slc25a36 deficiency, mtDNA of knockdown cells declined, leading to
            impaired mitochondria with swollen morphology, decreased
            mitochondrial membrane potential, and low numbers.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3061)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3061)
  AUTHORS   Hildyard,J.C. and Halestrap,A.P.
  TITLE     Identification of the mitochondrial pyruvate carrier in
            Saccharomyces cerevisiae
  JOURNAL   Biochem J 374 (Pt 3), 607-611 (2003)
   PUBMED   12887330
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC121121.13.
            
            On May 1, 2007 this sequence version replaced NM_138756.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK078779.1, BC008171.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-131               AC121121.13        2513-2643
            132-296             AC121121.13        13315-13479
            297-374             AC121121.13        16374-16451
            375-475             AC121121.13        20377-20477
            476-542             AC121121.13        28431-28497
            543-832             AC121121.13        33072-33361
            833-3061            AC121121.13        34315-36543
FEATURES             Location/Qualifiers
     source          1..3061
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 50.84 cM"
     gene            1..3061
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
                     /note="solute carrier family 25, member 36"
                     /db_xref="GeneID:192287"
                     /db_xref="MGI:MGI:1924909"
     exon            1..131
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..1026
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
                     /codon_start=1
                     /product="solute carrier family 25 member 36"
                     /protein_id="NP_620095.1"
                     /db_xref="CCDS:CCDS23420.1"
                     /db_xref="GeneID:192287"
                     /db_xref="MGI:MGI:1924909"
                     /translation="MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYIS
                     EVQLNTMAGASVNRVVSPGPLHCLKAILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAY
                     SNCKEKLNGVFDPDSTQVHMASAAMAGFTAITATNPIWLIKTRLQLDARTRGEKQMGA
                     FECVRKVYQTDGLRGFYRGMSASYAGISETVIHFVIYESIKQKLLECKTASMMETDEE
                     SVKEASDFVRMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLIVQEEG
                     YGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG"
     exon            132..296
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            297..374
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            375..475
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            476..542
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            543..832
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            833..3061
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2274..2279
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2315
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
                     /note="major polyA site"
     regulatory      2574..2579
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
                     /note="hexamer: AATGAA"
     polyA_site      2596
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
     regulatory      2656..2661
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2688
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
     regulatory      2758..2763
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2788
                     /gene="Slc25a36"
                     /gene_synonym="C330005L02Rik"
ORIGIN      
        1 gcgtccccct tcttggccct cgccgctggc cgtggcggcc tgctgggtcc gcgtcccgcc
       61 tctactcccg gaggacatgc agaagagaga atgagccaga gggacacgct ggtgcatctg
      121 tttgccgggg gatgtggtgg cacagtggga gctattctga catgtccact ggaagttgtc
      181 aaaacacggc tgcagtcttc ttctgtgaca ctgtatattt ctgaagttca gctgaacacc
      241 atggctggag ccagtgtgaa ccgagtagtg tcccctggac ctcttcattg tctgaaggct
      301 atcctggaaa aagagggccc tcgctcgttg tttagaggat tgggccccaa tttggtgggg
      361 gttgctccct ccagagcaat atactttgct gcttattcaa actgcaagga aaagttgaat
      421 ggtgtttttg atcctgattc tacccaagtg cacatggctt cagctgcaat ggcaggtttt
      481 actgcaatca ctgcaacaaa ccccatttgg cttataaaga ctcgcttaca gcttgatgca
      541 aggactcgtg gggaaaagca aatgggtgct tttgaatgtg ttcgtaaagt ctatcagaca
      601 gacggactgc gaggatttta taggggcatg tctgcctcct atgccggcat atcagagact
      661 gttatccatt ttgttattta tgaaagtata aagcaaaaac tactggaatg taagactgct
      721 tctatgatgg aaactgatga ggagtctgtg aaagaagcat cggattttgt gagaatgatg
      781 ctagctgctg ccacctcaaa aacctgtgcc acaaccatag cgtatccaca cgaagttgta
      841 agaacaagac tacgtgaaga agggacaaaa tataggtctt tttttcaaac attgtctttg
      901 attgttcaag aagaaggcta tggatctctt taccgcggtc taacaactca tctggtgagg
      961 cagattccaa acacggccat tatgatggcc acctacgaac tggtggtcta ccttctcaac
     1021 ggatagcagc aagggctgcc atactgcaga gcaggaagac caaaagatca cagtggacca
     1081 tggaatcttg aagccagcca gcatggtgga cagaagacag tagttgggaa acatgtaact
     1141 actatggctg agtggaagtt tggttttagg aagtaaggta ccatacgaca ttaatctttc
     1201 agtgagtaaa ccctgggccg cctcgtcaag aatgctttga aaagcattcc tttctcaaaa
     1261 ttgccatttt ctctattgtt caccagctcc agtttgtttt actggtttat gacattcaga
     1321 atacagtgtt gattccatga gcatttttgg ttgtttaaac aaaatcattc ctaagtgtat
     1381 actgtactgt aattttccaa agatggtagt gacaattaca aatgactaac ttgaacgtct
     1441 gcaatactgt aaaataacaa gtcgatcctc agtaacactt ccccaggagg gcctgcctgt
     1501 tacagtgttt tatgttatct gacacccata atcactgtat tttgacagcc agtgaagtag
     1561 tatctaaata cttcacattt tcaacatcaa aatgttatgg tcacatctaa aagatctcca
     1621 tcataattga acatatcaaa caaacacaca cagctaatgg tttgggacta taaaataagc
     1681 tagtggatac tgactcagtg acttagcatc ctcatacctt ttccaattat gtgatgcagg
     1741 tatggatata attttgattc ataatgtgat tatcacagtc tcatacctac atattattta
     1801 ctttaaaagt agaaaactaa caacttgaat tttttctact tactttcaca ttaagaattt
     1861 taacctttga attatttcca catctgtata agttattctt tgttggtaga ggaaatggta
     1921 attttcagtt ttgcccttta taggctcctt gaagtgatat taatatttag gacaatataa
     1981 atattacaaa aagacacgct cagctatcag atacaataaa tcttagttgg cagagagcct
     2041 gtaagcgagt gtgctacatt gcacaaatgt tattcctagt tccctaaatg ctctctcata
     2101 gagtcaggct agttttagtt cattgtgtta acaagataat agtttttaaa ttttgctgtt
     2161 gagtcaacaa catgtttgaa tactttaata tatatggcca ttataaaggt atttgctgca
     2221 atactataga ttttcctatg gatgttgcta tactggcata tgaaacgtct acaattaaac
     2281 tctagtgtgg tgctcatcag aggaccttca ctttacactt tgtgcaatgg ctttctcttc
     2341 agaatgactt tgtgaatgca ctttgtggcc ttttgagggg gtaagggtca ggagagaatt
     2401 catgttaatt tctttaacat tgttatgtat taggcagaag cagtgttcat aatatttttc
     2461 tggattttag gtatgttttg gagatcttac agtattttaa gtatgctgtg taatgccaca
     2521 ttattatgga aaaaaatagc cgcatgccat tgaaagcttt ctctgctgtc accaatgaag
     2581 tttaatccct cttaaatttc tcaccttgac ttccttgtaa tcagtaactg gatgtttttg
     2641 aggtgctcaa ttggaattaa aaatattcca atctatttgg agaccaaagg cacgtttaga
     2701 tccgttacct ttggaattat tgtagctttg acatctatga catggaacat accaaaaaat
     2761 aaatccccac gcaggggttt aacttaaatg tgtagagaag gtctcaggct atagtgtttg
     2821 cctcttcagg tgccactgat actgcctaat acagcgccat ttgctctgtg aagatcaata
     2881 acaattatgt tgaatgtcag acatgttctc ctgtgttaca cagatctcag atgatgaaga
     2941 atgacatgaa aaccagcagc caaggaacag cttgtgttgt cgtagcaagt ccacaataag
     3001 tgtccttcag ggataacatg tagcagtcgg tattttacaa gtaaaactca cattagcctc
     3061 t
//
