LOCUS       NM_133668               1550 bp    mRNA    linear   ROD 09-FEB-2024
DEFINITION  Mus musculus solute carrier family 25 (mitochondrial carrier,
            phosphate carrier), member 3 (Slc25a3), mRNA.
ACCESSION   NM_133668
VERSION     NM_133668.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1550)
  AUTHORS   Nakanishi,T., Kawasaki,Y., Nakamura,Y., Kimura,Y., Kawamura,K.,
            Shumba,M.N. and Shimokawa,N.
  TITLE     An implication of the mitochondrial carrier SLC25A3 as an oxidative
            stress modulator in NAFLD
  JOURNAL   Exp Cell Res 431 (1), 113740 (2023)
   PUBMED   37557977
  REMARK    GeneRIF: An implication of the mitochondrial carrier SLC25A3 as an
            oxidative stress modulator in NAFLD.
REFERENCE   2  (bases 1 to 1550)
  AUTHORS   Montanes-Agudo,P., Aufiero,S., Schepers,E.N., van der Made,I.,
            Cocera-Ortega,L., Ernault,A.C., Richard,S., Kuster,D.W.D.,
            Christoffels,V.M., Pinto,Y.M. and Creemers,E.E.
  TITLE     The RNA-binding protein QKI governs a muscle-specific alternative
            splicing program that shapes the contractile function of
            cardiomyocytes
  JOURNAL   Cardiovasc Res 119 (5), 1161-1174 (2023)
   PUBMED   36627242
REFERENCE   3  (bases 1 to 1550)
  AUTHORS   Wang,Y., Yen,F.S., Zhu,X.G., Timson,R.C., Weber,R., Xing,C.,
            Liu,Y., Allwein,B., Luo,H., Yeh,H.W., Heissel,S., Unlu,G.,
            Gamazon,E.R., Kharas,M.G., Hite,R. and Birsoy,K.
  TITLE     SLC25A39 is necessary for mitochondrial glutathione import in
            mammalian cells
  JOURNAL   Nature 599 (7883), 136-140 (2021)
   PUBMED   34707288
REFERENCE   4  (bases 1 to 1550)
  AUTHORS   Peoples,J.N., Ghazal,N., Duong,D.M., Hardin,K.R., Manning,J.R.,
            Seyfried,N.T., Faundez,V. and Kwong,J.Q.
  TITLE     Loss of the mitochondrial phosphate carrier SLC25A3 induces
            remodeling of the cardiac mitochondrial protein acylome
  JOURNAL   Am J Physiol Cell Physiol 321 (3), C519-C534 (2021)
   PUBMED   34319827
  REMARK    GeneRIF: Loss of the mitochondrial phosphate carrier SLC25A3
            induces remodeling of the cardiac mitochondrial protein acylome.
REFERENCE   5  (bases 1 to 1550)
  AUTHORS   Boulet,A., Vest,K.E., Maynard,M.K., Gammon,M.G., Russell,A.C.,
            Mathews,A.T., Cole,S.E., Zhu,X., Phillips,C.B., Kwong,J.Q.,
            Dodani,S.C., Leary,S.C. and Cobine,P.A.
  TITLE     The mammalian phosphate carrier SLC25A3 is a mitochondrial copper
            transporter required for cytochrome c oxidase biogenesis
  JOURNAL   J Biol Chem 293 (6), 1887-1896 (2018)
   PUBMED   29237729
  REMARK    GeneRIF: SLC25A3 is a mitochondrial copper transporter.
REFERENCE   6  (bases 1 to 1550)
  AUTHORS   Kwong,J.Q., Davis,J., Baines,C.P., Sargent,M.A., Karch,J., Wang,X.,
            Huang,T. and Molkentin,J.D.
  TITLE     Genetic deletion of the mitochondrial phosphate carrier
            desensitizes the mitochondrial permeability transition pore and
            causes cardiomyopathy
  JOURNAL   Cell Death Differ 21 (8), 1209-1217 (2014)
   PUBMED   24658400
REFERENCE   7  (bases 1 to 1550)
  AUTHORS   Baseler,W.A., Thapa,D., Jagannathan,R., Dabkowski,E.R.,
            Croston,T.L. and Hollander,J.M.
  TITLE     miR-141 as a regulator of the mitochondrial phosphate carrier
            (Slc25a3) in the type 1 diabetic heart
  JOURNAL   Am J Physiol Cell Physiol 303 (12), C1244-C1251 (2012)
   PUBMED   23034391
  REMARK    GeneRIF: The results indicated that miR-141 can regulate Slc25a3
            protein expression in the diabetic heart. Further, diabetes-induced
            miRNA changes may influence mitochondrial proteomes and functional
            processes such as mitochondrial ATP production.
REFERENCE   8  (bases 1 to 1550)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
REFERENCE   9  (bases 1 to 1550)
  AUTHORS   Baughman,G., Harrigan,M.T., Campbell,N.F., Nurrish,S.J. and
            Bourgeois,S.
  TITLE     Genes newly identified as regulated by glucocorticoids in murine
            thymocytes
  JOURNAL   Mol Endocrinol 5 (5), 637-644 (1991)
   PUBMED   2072923
REFERENCE   10 (bases 1 to 1550)
  AUTHORS   Harrigan,M.T., Baughman,G., Campbell,N.F. and Bourgeois,S.
  TITLE     Isolation and characterization of glucocorticoid- and cyclic
            AMP-induced genes in T lymphocytes
  JOURNAL   Mol Cell Biol 9 (8), 3438-3446 (1989)
   PUBMED   2552295
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK150641.1, AK077274.1 and BP769168.1.
            
            [WARNING] On Mar 22, 2024 this sequence was replaced by
            NM_133668.5.
            
            On Jun 23, 2018 this sequence version replaced NM_133668.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK151887.1, AK077274.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849379
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 AK150641.1         2-5
            5-1516              AK077274.1         2-1513
            1517-1550           BP769168.1         1-34                c
FEATURES             Location/Qualifiers
     source          1..1550
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 45.6 cM"
     gene            1..1550
                     /gene="Slc25a3"
                     /gene_synonym="5730556H19Rik; Phc; PTP"
                     /note="solute carrier family 25 (mitochondrial carrier,
                     phosphate carrier), member 3"
                     /db_xref="GeneID:18674"
                     /db_xref="MGI:MGI:1353498"
     exon            1..52
                     /gene="Slc25a3"
                     /gene_synonym="5730556H19Rik; Phc; PTP"
                     /inference="alignment:Splign:2.1.0"
     exon            53..201
                     /gene="Slc25a3"
                     /gene_synonym="5730556H19Rik; Phc; PTP"
                     /inference="alignment:Splign:2.1.0"
     exon            202..323
                     /gene="Slc25a3"
                     /gene_synonym="5730556H19Rik; Phc; PTP"
                     /inference="alignment:Splign:2.1.0"
     exon            324..503
                     /gene="Slc25a3"
                     /gene_synonym="5730556H19Rik; Phc; PTP"
                     /inference="alignment:Splign:2.1.0"
     exon            504..685
                     /gene="Slc25a3"
                     /gene_synonym="5730556H19Rik; Phc; PTP"
                     /inference="alignment:Splign:2.1.0"
     exon            686..858
                     /gene="Slc25a3"
                     /gene_synonym="5730556H19Rik; Phc; PTP"
                     /inference="alignment:Splign:2.1.0"
     exon            859..969
                     /gene="Slc25a3"
                     /gene_synonym="5730556H19Rik; Phc; PTP"
                     /inference="alignment:Splign:2.1.0"
     exon            970..1520
                     /gene="Slc25a3"
                     /gene_synonym="5730556H19Rik; Phc; PTP"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctgtgagc cgcaaccttg cccagcgagc ggttgggtgt tcgccatctt aggaggatgt
       61 tctcgtccgt agcgcacctg gcgcgggcga accccttcaa cgcgccacac ctgcagctgg
      121 tgcacgatgg cctgtcgggt ccccgcagtc ccccagctcc gccccggcgt tcccgccacc
      181 tggccgccgc cgccgtggaa gagtacagtt gtgaatttgg ctccatgaag tattatgcac
      241 tgtgtggctt tggtggggtc ttaagttgtg ggctgacaca cactgctgtt gttcccctgg
      301 acttagtaaa gtgccgcatg caggtggacc ctcagaagta caaaggcata tttaatggat
      361 tctccattac actgaaagaa gatggcgttc gtggtttggc taaaggatgg gccccaactt
      421 tgattggcta ttccatgcaa gggctctgca aattcggctt ttatgaagtc ttcaaagcct
      481 tatatagcaa catacttggt gaggaaaaca cctacctgtg gcgcacatca ctgtatttag
      541 cttcttctgc cagtgctgaa ttcttcgctg acattgccct ggctcctatg gaagctgcta
      601 aagttcgaat tcaaacccag cctggttatg ccaacacctt gagggaagct gttcccaaaa
      661 tgtataaaga ggaaggctta aatgcgttct acaagggcgt tgctcctctg tggatgagac
      721 agatcccgta caccatgatg aagttcgcct gctttgaacg tactgttgaa gctttgtaca
      781 aatttgtggt tcctaagccc cgaagtgaat gtacaaaggc agagcagctg gttgtgacat
      841 ttgtggcagg ttacatagct ggagtcttct gtgcgatcgt ctcccaccct gctgactctg
      901 tggtctctgt gctgaataaa gagaaaggca gcaccgcgtc tcaggtcctg cagaggctgg
      961 gcttcagagg tgtgtggaag gggctcttcg cccgaatcat catgattggc actctgactg
     1021 cactacagtg gttcatctac gactctgtga aggtctactt caggctccct cgccctcctc
     1081 cccctgagat gccagagtct ctgaagaaga agcttgggtt aactgagtag atacatcaaa
     1141 gtaacatgga ctgaatctgc ttgttgatca gtgttgaaag tgcaaaggaa cttttatata
     1201 tttgacagtg taggaaatgt ctgttcctga tataattact gtagtaccct tgcttaaagc
     1261 aagagtttca aacttaatgc taaataaacc catctattcc tgatgtctat gagtttgtta
     1321 ttttaaaaac tagtattgaa aaaagattta gtcctaaaac aaaaagaata attaaggtat
     1381 tcaccccagg aaaaaagtgt aaactaagta aaccattggt gctattccta aattgtcccc
     1441 tcacttaaga aactcctgtg tttaggaaat agtcttgggt tttcaaaaac atggtttatt
     1501 aaatatggat aaacactgaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
