LOCUS       NM_172685               3383 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus solute carrier family 25 (mitochondrial carrier,
            phosphate carrier), member 24 (Slc25a24), mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_172685
VERSION     NM_172685.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3383)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3383)
  AUTHORS   Liu,Y., Liu,N., He,P., Cao,S., Li,H. and Liu,D.
  TITLE     Arginine-methylated c-Myc affects mitochondrial mitophagy in mouse
            acute kidney injury via Slc25a24
  JOURNAL   J Cell Physiol 239 (1), 193-211 (2024)
   PUBMED   38164038
  REMARK    GeneRIF: Arginine-methylated c-Myc affects mitochondrial mitophagy
            in mouse acute kidney injury via Slc25a24.
REFERENCE   3  (bases 1 to 3383)
  AUTHORS   Urano,T., Shiraki,M., Sasaki,N., Ouchi,Y. and Inoue,S.
  TITLE     SLC25A24 as a novel susceptibility gene for low fat mass in humans
            and mice
  JOURNAL   J Clin Endocrinol Metab 100 (4), E655-E663 (2015)
   PUBMED   25599384
  REMARK    GeneRIF: Genetic analyses in human and mouse models revealed the
            importance of SLC25A24/Slc25a24 in the regulation of body fat mass
            and adipogenesis.
REFERENCE   4  (bases 1 to 3383)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 3383)
  AUTHORS   Amigo,I., Traba,J., Gonzalez-Barroso,M.M., Rueda,C.B.,
            Fernandez,M., Rial,E., Sanchez,A., Satrustegui,J. and Del Arco,A.
  TITLE     Glucagon regulation of oxidative phosphorylation requires an
            increase in matrix adenine nucleotide content through Ca2+
            activation of the mitochondrial ATP-Mg/Pi carrier SCaMC-3
  JOURNAL   J Biol Chem 288 (11), 7791-7802 (2013)
   PUBMED   23344948
REFERENCE   6  (bases 1 to 3383)
  AUTHORS   Traba,J., Del Arco,A., Duchen,M.R., Szabadkai,G. and Satrustegui,J.
  TITLE     SCaMC-1 promotes cancer cell survival by desensitizing
            mitochondrial permeability transition via ATP/ADP-mediated matrix
            Ca(2+) buffering
  JOURNAL   Cell Death Differ 19 (4), 650-660 (2012)
   PUBMED   22015608
  REMARK    GeneRIF: SCaMC-1 exerts a negative feedback control between
            cellular Ca(2+) overload and mPT-dependent cell death, suggesting
            that the carrier might represent a novel target for cancer therapy.
REFERENCE   7  (bases 1 to 3383)
  AUTHORS   del Arco,A. and Satrustegui,J.
  TITLE     Identification of a novel human subfamily of mitochondrial carriers
            with calcium-binding domains
  JOURNAL   J Biol Chem 279 (23), 24701-24713 (2004)
   PUBMED   15054102
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL671921.16
            and AL845310.4.
            
            On May 2, 2007 this sequence version replaced NM_172685.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK032806.1, AK146034.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-239               AL671921.16        101838-102076
            240-366             AL671921.16        114901-115027
            367-454             AL845310.4         6728-6815
            455-566             AL845310.4         12239-12350
            567-725             AL845310.4         14092-14250
            726-872             AL845310.4         15743-15889
            873-980             AL845310.4         16593-16700
            981-1148            AL845310.4         18462-18629
            1149-1299           AL845310.4         20664-20814
            1300-3383           AL845310.4         23571-25654
FEATURES             Location/Qualifiers
     source          1..3383
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 48.13 cM"
     gene            1..3383
                     /gene="Slc25a24"
                     /gene_synonym="2610016M12Rik; SCaMC-1"
                     /note="solute carrier family 25 (mitochondrial carrier,
                     phosphate carrier), member 24"
                     /db_xref="GeneID:229731"
                     /db_xref="MGI:MGI:1917160"
     exon            1..239
                     /gene="Slc25a24"
                     /gene_synonym="2610016M12Rik; SCaMC-1"
                     /inference="alignment:Splign:2.1.0"
     exon            240..366
                     /gene="Slc25a24"
                     /gene_synonym="2610016M12Rik; SCaMC-1"
                     /inference="alignment:Splign:2.1.0"
     exon            367..454
                     /gene="Slc25a24"
                     /gene_synonym="2610016M12Rik; SCaMC-1"
                     /inference="alignment:Splign:2.1.0"
     exon            455..566
                     /gene="Slc25a24"
                     /gene_synonym="2610016M12Rik; SCaMC-1"
                     /inference="alignment:Splign:2.1.0"
     exon            567..725
                     /gene="Slc25a24"
                     /gene_synonym="2610016M12Rik; SCaMC-1"
                     /inference="alignment:Splign:2.1.0"
     exon            726..872
                     /gene="Slc25a24"
                     /gene_synonym="2610016M12Rik; SCaMC-1"
                     /inference="alignment:Splign:2.1.0"
     exon            873..980
                     /gene="Slc25a24"
                     /gene_synonym="2610016M12Rik; SCaMC-1"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1148
                     /gene="Slc25a24"
                     /gene_synonym="2610016M12Rik; SCaMC-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1149..1299
                     /gene="Slc25a24"
                     /gene_synonym="2610016M12Rik; SCaMC-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1300..3383
                     /gene="Slc25a24"
                     /gene_synonym="2610016M12Rik; SCaMC-1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acaggcctcc gcactcggat cgcgccccac cagctcacgg tgacttcccc gggaccatgc
       61 tgcgctggct gcgggccttt gtgctgccca ccgccgcctg ccacgacgcg gagccgccca
      121 cacgctacga aacgctcttc cgggcgctgg accgcaatgg ggacggcgtg gtggacatcg
      181 gagagctgca gcaggggctg caaagcctgg gcatcccgct gggccaggac gcggaggaga
      241 aaattttcac cactggcgat gtcaacaaag atgggaagct ggattttgaa gaatttatga
      301 aatacctgaa agaccatgag aagaaaatga aattagcatt taaaagtttg gacaagaata
      361 atgacgggaa aatcgagcct tctgaaattg tccagtctct ccagatgctc ggtttacata
      421 tttctgaaaa gcaagcagag ctgattcttc aaagcatcga ctctgatggg acgatgaccg
      481 tggactggaa tgaatggagg gattactttt tatttaaccc tgtgacagac attgaggaaa
      541 ttatccgttt ctggaaacac tctactggaa ttgacatagg ggatagttta actattccag
      601 atgaattcac agaagatgag aaaaaatcag gacagtggtg gaggcagctc ctggcaggag
      661 gtgtggcggg cgccgtctct agaacgagca ccgctccttt ggatcgcctc aaggtcatga
      721 tgcaggttca tggttccaaa tcaatgaata tatttggagg ctttcggcag atggtaaagg
      781 aaggaggaat ccgttccctt tggagaggaa atggcaccaa tgtcatcaaa atagctcccg
      841 agacagctgt gaagttctgg gcttatgaac agtacaagaa gttgcttacc gaggaaggac
      901 aaaaattagg gacctttgag aggtttatct ctggttccat ggctggagca actgctcaga
      961 cttttattta ccccatggag gttttgaaaa cccggctagc tgtagccaaa actggacaat
     1021 actccggaat atacggttgt gccaagaaga ttttgaaaca cgaaggcttt ggggcttttt
     1081 acaaaggcta cattcccaat ttactaggca tcattcctta cgcaggcatt gatctcgctg
     1141 tgtacgagct tttgaagtct tattggctgg ataactttgc caaagactcg gtcaaccctg
     1201 gcgtgatggt gctgctgagc tgtggagccc tatccagcac ctgtgggcag ctggccagct
     1261 accccctggc tttggtgaga actcgcatgc aggctcaagc cacggtagaa ggagccccgc
     1321 agctgagcat ggttggcctt tttcagcgaa tcgtctccaa agaaggagtg tcaggacttt
     1381 acagaggcat caccccaaac ttcatgaaag tgctcccggc cgtgggcatc agctatgtgg
     1441 tgtatgaaaa tatgaagcag accctgggag tagctcagaa gtgaccagtc caagcctttg
     1501 cttttctgtg gtgaccgaga ctgtcagtgc tctccagtga cttctggggt tgcatcaagt
     1561 ctatcacaaa ggaagctgtt tgcctcgcca aagggaagag tgtagccgtg atcactacaa
     1621 gcctttgggt tcagttttat accttcagcg atgctctgaa tcgtagttcc agtaagtgaa
     1681 gaaaccacaa aattgtactg tatttttgct gatagagatc tctgccctgc accctaaatc
     1741 tgaaaatgta ctggcttgag atgaaatcat tttgtgtggt aggattataa atcactaacc
     1801 tttgttctga ttggttcaag ctcatgtcaa tttttctttt tcacccaaac tttaaaaaaa
     1861 tcaaaaatga tcagaaagcc tcaggactta aattgtttaa tatattttag atgtctttgt
     1921 agatgtaaaa gttcccaaca gagacattag tagaaaaatc actatattca aagtctactt
     1981 tgcacagttt atctcctcat ctgtaagcag aataggaatg aattatagaa ggcacattca
     2041 gcggacagga gccgtgaggt aatgcttatt tcagtgggca tgcttctttc tacttgccct
     2101 gctgtttggc cctagtttta gaccttgatt gacattgttg ttacattatt gacaggggac
     2161 aggtcatttg gaagatcata tttattcggt catcactttg aaaagcatca atgaacaaaa
     2221 ctgtgacttg taccatttcc cagtgagcat cttggttttg ttcatttttt ttactcattt
     2281 aatcaaattc tcttaatcag gaaggctcct tgggaccttc acagtaatct gaaactgccc
     2341 ttctcctact tgagtgtcaa gttcaggtaa ataaaccctt gtttccctct tactgttgag
     2401 gtctttgaac ctgtgcttct caaatggagc ggcacaaagc taaggcacca gcacacttca
     2461 atagtagtat atattcatct acctgtttta atgaaaggct caatctgcat aatattcatc
     2521 tacatattca cttgcctcaa gatttaggaa gatgacagaa aatttgtaat atcaagagca
     2581 tttccttttt ttaaactaaa gctgattttg tagtctttta tgatttattt taaaacttag
     2641 aaaaatatta ttttttctat aagaagatgt ttgatagtct tagcctggca atattggcac
     2701 atgcctttag ttctagcact caggaggcag aggtgggcat atctctgagt ttgaggccag
     2761 cctggtctac agagagagtt ccagggcagc taggggcaca cagagaaacc ctgtctccaa
     2821 aacaaaacaa ccccaaccaa acaaaaaaga tagttttaat gttttaagat ttagtccata
     2881 tactcatttg gtttctggta atttctatat agttgctttc tgaaaagtct agtgaaaatc
     2941 tttaccttta aacctaccta cctctttttt tttttgaacc aaagagaaag atggcctgtg
     3001 tttatgaaac ttattctaaa acacagcttg gtttgtacta cggatgcctg cattgtcttg
     3061 gtatttttgt actatataaa gaaaggaggg gactctgctt catcttcggg gttattgtat
     3121 tttggagtaa tacctagaat gacaatatta aggtacatga ttcacacctt ttttaaaatg
     3181 tgtaacaatt atggaaatgc atattactgt taatgtcttt ggaattttaa gttgataaaa
     3241 actatgaaaa tggccatact tcattatgaa attgaatcgt ctcccagtga acatgtgtaa
     3301 ggtatgactg atttatctgt acatcttgta tcttttttgg ggaaaaaacc ctcctattga
     3361 acacagctta ttctgatatt gct
//
