LOCUS       NM_134256               2165 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus solute carrier family 22, member 27 (Slc22a27),
            transcript variant 1, mRNA.
ACCESSION   NM_134256 XM_922697 XM_984546
VERSION     NM_134256.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2165)
  AUTHORS   Tsuchida,H., Anzai,N., Shin,H.J., Wempe,M.F., Jutabha,P.,
            Enomoto,A., Cha,S.H., Satoh,T., Ishida,M., Sakurai,H. and Endou,H.
  TITLE     Identification of a novel organic anion transporter mediating
            carnitine transport in mouse liver and kidney
  JOURNAL   Cell Physiol Biochem 25 (4-5), 511-522 (2010)
   PUBMED   20332632
  REMARK    GeneRIF: Oat9S appears to be the first member to mediate the
            transport of carnitine and possesses eight transmembrane domains.
REFERENCE   2  (bases 1 to 2165)
  AUTHORS   Wu,W., Baker,M.E., Eraly,S.A., Bush,K.T. and Nigam,S.K.
  TITLE     Analysis of a large cluster of SLC22 transporter genes, including
            novel USTs, reveals species-specific amplification of subsets of
            family members
  JOURNAL   Physiol Genomics 38 (2), 116-124 (2009)
   PUBMED   19417012
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB056442.1.
            
            On or before Jun 27, 2009 this sequence version replaced
            XM_922697.2, XM_984546.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB056442.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN00849386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on computational evidence
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..2165
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 5.36 cM"
     gene            1..2165
                     /gene="Slc22a27"
                     /gene_synonym="OAT6-L; OAT6-S; Oat9"
                     /note="solute carrier family 22, member 27"
                     /db_xref="GeneID:171405"
                     /db_xref="MGI:MGI:3042283"
     exon            1..66
                     /gene="Slc22a27"
                     /gene_synonym="OAT6-L; OAT6-S; Oat9"
                     /inference="alignment:Splign:2.1.0"
     exon            67..509
                     /gene="Slc22a27"
                     /gene_synonym="OAT6-L; OAT6-S; Oat9"
                     /inference="alignment:Splign:2.1.0"
     CDS             108..1763
                     /gene="Slc22a27"
                     /gene_synonym="OAT6-L; OAT6-S; Oat9"
                     /note="isoform 1 is encoded by transcript variant 1;
                     organic anion transporter 6; mOAT6 related protein;
                     organic anion transporter 9"
                     /codon_start=1
                     /product="solute carrier family 22 member 27 isoform 1"
                     /protein_id="NP_599017.1"
                     /db_xref="CCDS:CCDS50380.1"
                     /db_xref="GeneID:171405"
                     /db_xref="MGI:MGI:3042283"
                     /translation="MSFQELLNQVGSLGRFQILQIVFLLLLNAIVVPHIAMENFTAAI
                     PNHRCWVPILDNDTASDNGSRILSQDDLLRISIPLDSNLRPEKCRRFAQPQWHLLHLN
                     GTFSNVSEPDTEPCVDGWVYDRSNFLSTIVTEWDLVCESQALNSVTKFSFMIGLFIGG
                     IICGHLSDRLGRKFILTCALLQFAITETCVAFAPSFFIYCSLRFLAGLSVEPILVNSH
                     LLMLEWTSPKFLTMMAALLSCAPNIGYMISAGLAFLFRIWHHLQLTMSVPIFFFLILT
                     RWLSESARWLIVTNKPQKGLKELRKVAHMNGMKNSGDLTMEIVRTSMKAELEAAKTKP
                     SLRDLFHTSILRKRICVLSFMRLFFTVSIFGLAVHLQHLSSNIILLQFLISALAILVS
                     VIGPFVLNHIGRRITYLVLMSLRGIFILIAVFVPQEMQTLRIIMATLAEGISSLCVGV
                     SRLHTNELLPTTLRATAVGVIGFFGNSGSFLSPLFMLLATYYANMPWIFYGGFSIFNA
                     FTVFLLPETKNQPLPDSTHDVGNDWKESRKGKKEDPIIKVTRF"
     exon            510..613
                     /gene="Slc22a27"
                     /gene_synonym="OAT6-L; OAT6-S; Oat9"
                     /inference="alignment:Splign:2.1.0"
     exon            614..768
                     /gene="Slc22a27"
                     /gene_synonym="OAT6-L; OAT6-S; Oat9"
                     /inference="alignment:Splign:2.1.0"
     exon            769..937
                     /gene="Slc22a27"
                     /gene_synonym="OAT6-L; OAT6-S; Oat9"
                     /inference="alignment:Splign:2.1.0"
     exon            938..1058
                     /gene="Slc22a27"
                     /gene_synonym="OAT6-L; OAT6-S; Oat9"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1174
                     /gene="Slc22a27"
                     /gene_synonym="OAT6-L; OAT6-S; Oat9"
                     /inference="alignment:Splign:2.1.0"
     exon            1175..1389
                     /gene="Slc22a27"
                     /gene_synonym="OAT6-L; OAT6-S; Oat9"
                     /inference="alignment:Splign:2.1.0"
     exon            1390..1498
                     /gene="Slc22a27"
                     /gene_synonym="OAT6-L; OAT6-S; Oat9"
                     /inference="alignment:Splign:2.1.0"
     exon            1499..1702
                     /gene="Slc22a27"
                     /gene_synonym="OAT6-L; OAT6-S; Oat9"
                     /inference="alignment:Splign:2.1.0"
     exon            1703..2152
                     /gene="Slc22a27"
                     /gene_synonym="OAT6-L; OAT6-S; Oat9"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2122..2127
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc22a27"
                     /gene_synonym="OAT6-L; OAT6-S; Oat9"
                     /note="hexamer: AATAAA"
     polyA_site      2152
                     /gene="Slc22a27"
                     /gene_synonym="OAT6-L; OAT6-S; Oat9"
                     /note="major polyA site"
ORIGIN      
        1 gacactgagc cctgtgtgga tggatgggtg tgttacagga gcaacttctt atccactgtg
       61 atcgagtaaa gtctttgtct ccctttggaa atagttattc agcctcaatg tcctttcaag
      121 aactcctgaa tcaagttgga agcctaggaa gattccagat ccttcagata gtttttcttt
      181 tactcctcaa tgccattgtg gtacctcata ttgcaatgga gaactttact gcagccattc
      241 ccaatcatcg ctgctgggtc cccatccttg acaatgacac tgcctctgat aatggcagta
      301 ggatcctgag ccaagatgac ctcctgagga tctccatccc cctggattcc aacctgaggc
      361 cagagaagtg tcgtcgtttt gcccaaccac agtggcatct tcttcatttg aatggcactt
      421 tctccaatgt gtcagagcca gacactgagc cctgtgtgga tggttgggtg tatgacagga
      481 gcaacttcct ttctaccatt gtgactgagt gggacttggt atgtgaatcc caggcactga
      541 attctgtcac taaattttca ttcatgattg gcctatttat agggggtatc atatgtggcc
      601 atctgtcaga caggcttggg aggaagttca ttttaacatg tgctttatta caatttgcca
      661 tcactgaaac ctgtgtagct tttgccccct ccttcttcat ctactgctca cttcgattcc
      721 tggcaggatt gtctgtggaa cccatattag taaatagtca cttgctcatg ttagaatgga
      781 caagccctaa atttctaacc atgatggcag cgcttttatc ttgtgctcct aatattggat
      841 acatgatatc agcaggcctg gcttttctat ttagaatctg gcatcacctc cagctgacaa
      901 tgtctgtgcc aatattcttc ttccttatac tcacaaggtg gctgtcagag tcagctcggt
      961 ggctgattgt gaccaacaaa ccccagaagg gcttaaagga acttagaaaa gttgcacaca
     1021 tgaatggaat gaagaattct ggagacctaa ccatggagat tgtgagaaca agtatgaagg
     1081 cagaacttga ggcagcaaag actaaacctt ctctaagaga tttgttccat acatctatcc
     1141 tacgtaagcg gatatgtgtc ctgtccttta tgagactttt ttttacagta tcaatttttg
     1201 gcctggcagt tcacctccaa cacctgagtt ctaatattat cctgttgcag tttctcatta
     1261 gtgcattggc catactagtc agtgttattg gaccttttgt acttaatcac attggccgta
     1321 gaataaccta tctggttctc atgtctctga ggggaatctt cattctgatt gctgtatttg
     1381 tacctcaaga aatgcagacc ctgcgtatta ttatggccac attggcagaa ggaatttctt
     1441 ctctgtgtgt gggtgttagt cgtcttcata caaatgagct actcccaacc acactaaggg
     1501 caacagctgt aggagtcatt gggttctttg gtaatagtgg atcattccta tcccccctgt
     1561 ttatgctgct agcgacatac tatgccaaca tgccctggat cttctatgga ggcttctcca
     1621 tcttcaacgc gtttactgtg tttctccttc ctgaaaccaa gaatcagcct cttcctgact
     1681 ccacccatga tgtaggaaat gattggaaag aatcaagaaa aggaaagaag gaggatccca
     1741 tcattaaagt cacgaggttt taaggaactc ctggaattgt catctgatca aagaataaga
     1801 gaagaaaatg gtattcagaa catggcgaca attttcccag gatcattact cagaagtatt
     1861 cactgatatt atcaaaagta ttaataactc aagataaaac agaaaactga tcacactgga
     1921 attgctacaa tcgattacta tatgttaaat acctatgagt aatcacatag gtaatttgaa
     1981 gtattggaac gaacattgaa agattttaaa agtacattga aaaaatcata cttgacaatt
     2041 tttgcaatca tgtacacctg ttttgttttg agatggtata tctattctat ttttccactt
     2101 ctgtgatata atacctgagg aaataaaagg aagtaatcct ttttccccca aaaaaaaaaa
     2161 aaaaa
//
