LOCUS       NM_001033167            6251 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus solute carrier family 22, member 23 (Slc22a23),
            transcript variant 1, mRNA.
ACCESSION   NM_001033167 XM_127295 XM_911058
VERSION     NM_001033167.3
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6251)
  AUTHORS   Christoforou,N., Miller,R.A., Hill,C.M., Jie,C.C., McCallion,A.S.
            and Gearhart,J.D.
  TITLE     Mouse ES cell-derived cardiac precursor cells are multipotent and
            facilitate identification of novel cardiac genes
  JOURNAL   J Clin Invest 118 (3), 894-903 (2008)
   PUBMED   18246200
REFERENCE   2  (bases 1 to 6251)
  AUTHORS   Jacobsson,J.A., Haitina,T., Lindblom,J. and Fredriksson,R.
  TITLE     Identification of six putative human transporters with structural
            similarity to the drug transporter SLC22 family
  JOURNAL   Genomics 90 (5), 595-609 (2007)
   PUBMED   17714910
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC129019.4, AC102087.12 and AC139242.2.
            
            On May 2, 2007 this sequence version replaced NM_001033167.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147397.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164141 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1024              AC129019.4         83664-84687         c
            1025-1128           AC102087.12        209802-209905       c
            1129-1283           AC102087.12        203641-203795       c
            1284-1452           AC102087.12        126547-126715       c
            1453-1580           AC139242.2         188165-188292       c
            1581-1683           AC139242.2         182050-182152       c
            1684-1916           AC139242.2         179500-179732       c
            1917-1949           AC139242.2         177642-177674       c
            1950-1973           AC139242.2         177497-177520       c
            1974-2097           AC139242.2         176404-176527       c
            2098-6251           AC139242.2         163406-167559       c
FEATURES             Location/Qualifiers
     source          1..6251
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 14.05 cM"
     gene            1..6251
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /note="solute carrier family 22, member 23"
                     /db_xref="GeneID:73102"
                     /db_xref="MGI:MGI:1920352"
     exon            1..1024
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             386..2455
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="solute carrier family 22 member 23 isoform 1"
                     /protein_id="NP_001028339.1"
                     /db_xref="CCDS:CCDS26446.1"
                     /db_xref="GeneID:73102"
                     /db_xref="MGI:MGI:1920352"
                     /translation="MAIDRRREAAGSGAGRQPAPAEENGSLPPGDAAASAPLGGRAGS
                     GSSAEIQPLPALHPSGGPHSSCCAATAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVVL
                     TWIPALFIGFSQFSDSFLLDQPDFWCRGAGKGTELAGATVTGRWGDMGNWTSPSATPF
                     STASWGTTSNRSNSSDTPPLPSPPGKGNNDSNCDCHAWDYGIRTGLIQNVVSKWDLVC
                     DNTWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSTIFILIFGLTVALSVNVT
                     MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFIITMVASFVAMAGQFLMPGLAALC
                     RDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKKLILYLTQKNCVSPESD
                     IKGVMPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGH
                     EVKVPLLENFYADYYTMASIALASCLAMCLVVKFLGRRGGLLLFMILTALASLLQLGL
                     LNLIGKYSQHPDSELQLKLAVGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEIT
                     PTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPES
                     RNQNLPENIANGEHYTRQPLLPHKKGEQPLLLTNAELKDYSGLHDVAAVGDGLPEGAT
                     ANGMKTM"
     exon            1025..1128
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1129..1283
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..1452
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1453..1580
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1581..1683
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1684..1916
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1917..1949
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1950..1973
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1974..2097
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2098..6251
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5745..5750
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /note="hexamer: AATAAA"
     polyA_site      5766
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /note="major polyA site"
     regulatory      6221..6226
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /note="hexamer: AATAAA"
     polyA_site      6240
                     /gene="Slc22a23"
                     /gene_synonym="3110004L20Rik"
                     /note="major polyA site"
ORIGIN      
        1 gaagtccgtg gaggatctcc caacccgcgg ccgccggcgg ccccagcaca acgcgcaccg
       61 gtgcccgcag ggccccgagt cgcgacaagg gcgcgggtcc ggctcctcct cctccccggc
      121 cggcgcgcat cagcggagag cctcgtagct aggcgggcgc ccgggccgcg gcgcggatga
      181 gccgcggcgg ctgaggactc gaacggtttc tgcccggcgc ccagggcacg ggggtgcgcg
      241 ggtgacatgg gggtggcctg actcgccggg cccggagcac tctctccggc cgcgggccct
      301 cctcctcggc ggcggcgctg tgcccgggcg cccgccgagc tccgccgcgc tctatgcgcc
      361 tctgcgggag ccgcgggccc tggccatggc gatagaccgg cggcgtgagg cggcgggtag
      421 tggtgccggg cggcagccgg ccccggcgga ggagaacggc tccctgccgc ccggggacgc
      481 ggcggcctcg gcgcccctcg gagggcgcgc gggctccggc agcagcgcgg agatccagcc
      541 actgcctgcg ctgcacccca gcggcggccc gcactcgagc tgctgcgcgg cgacagccgc
      601 cccgagcctc ctgttgctgg actacgatgg ctccgtgctg cccttcctcg ggggcctggg
      661 cggcggctac cagaagaccc tggtggtgct cacctggatc ccggcactgt tcattggctt
      721 cagccagttc tcggactcct tccttctgga ccagcccgat ttctggtgcc gcggggccgg
      781 caaaggcacc gagctggcgg gtgccactgt caccggccga tggggtgaca tgggcaattg
      841 gaccagcccc tcggccaccc ccttctccac tgcctcctgg gggaccacga gcaaccgaag
      901 caacagcagc gacacaccac ccctcccatc ccctccaggc aaggggaaca acgactcaaa
      961 ttgcgactgc cacgcgtggg actacggcat ccgcactggt ctcatccaaa acgtggtcag
     1021 caagtgggat cttgtgtgtg ataatacctg gaaagtccat atcgctaagt tctccttact
     1081 ggttggatta atctttggct acctaataac tggatgcatt gctgactggg ttggccggcg
     1141 gcctgtgctg ctgttttcca ccatcttcat cctcatcttt ggactgactg tggcactgtc
     1201 agtgaatgtg acaatgttca gcacactcag gttctttgaa ggattttgcc tggctggaat
     1261 catcctcacc ttgtatgcat tacgaataga gctatgccct ccaggaaaac ggttcataat
     1321 taccatggtg gcgagcttcg tggccatggc gggccagttc ctcatgccgg ggctggctgc
     1381 gctgtgccgg gactggcagg tgttgcaggc cctcatcatc tgtcccttcc tgctcatgct
     1441 gctctactgg tcgattttcc ctgagtctct ccgatggcta atggctaccc agcaatttga
     1501 atcagcaaag aagttgatcc tgtaccttac tcagaagaac tgtgtgagcc ctgagagtga
     1561 tatcaaggga gtgatgccag agctcgagaa agagctttca cggaggccca agaaggtgtg
     1621 catcgtgaag gtggtgggga cgaggaacct gtggaaaaac attgtggttc tctgtgtgaa
     1681 ctcgctgaca gggtacggga tccaccactg ctttgcaaga agcatgatgg gccatgaagt
     1741 gaaggtgccg ctcctggaga acttctacgc tgactactac accatggcca gcatcgcact
     1801 ggcctcctgc ctagccatgt gtctggtagt caagttcctc gggcgcaggg gagggctgct
     1861 gctcttcatg atcctcactg ccctggcctc acttctacag ctcgggcttc tcaacttgat
     1921 cggcaaatac agccagcatc cagactcaga attgcagctg aagttggccg tagggatgag
     1981 tgacagcgtc aaggacaagt tctccattgc gttttccatc gtgggaatgt ttgcatccca
     2041 tgcggtgggg agcctcagtg tcttcttctg tgcagagatc actcccacag tgataaggtg
     2101 tggtgggctc gggctggtgc tggccagtgc aggttttggc atgctgacag cgcccattat
     2161 tgagctgcac aaccaaaaag gctacttcct gcaccatatc atcttcgcct gctgcacgct
     2221 catctgcatc atttgcatcc tcctgcttcc tgagagcagg aaccagaacc tgcctgagaa
     2281 tatcgccaac ggggaacact acacacggca accgctgctg ccacacaaga agggagagca
     2341 gcccttgctg ctcaccaacg cggagctcaa ggactactcg ggcctgcatg acgtggctgc
     2401 agtgggtgac gggctgccag agggggccac tgccaatggc atgaagacta tgtagctcgc
     2461 tggaccacgc caccattcca ccagtccccc cggggcttga agggctgggg agagtttgca
     2521 cacaggttta cagaccaggg aggaagtcca tctctgctgc tgactccact caattgtgag
     2581 actttcaacc ggtgtgggga attctgtctt tccagacatc cgaggaacac atctgagaaa
     2641 ccagatgctc tggaaataac cctctgaaga ctttcttttc tgccattcaa tgtttgtatt
     2701 tattttggtc atttttacga gaagcacttt atccccttcc cccctccact gatcatgaag
     2761 cagaacctcc ttcaggagtg agggtcactc tgaggaagtc cctgtaagtg accaatgcag
     2821 tggccagtcc cctccctgga ggccagactc aatttccttc tccactcaag gagacagagg
     2881 tcatctgtag gccaggaccc ctacctccag gctccctgcc atggacagct gtgcctctca
     2941 agcagagagt ccttgggact acattttaca cagaggaaaa tgtacatgaa ttgttgtttt
     3001 tctttttttc ttttcctaga gtctgtatat tttaaagttg ggtactttac tttctgtttg
     3061 ttaggtagtt tccatgctgt gttgggaaaa cagcctccag atgtcatacg agccagctta
     3121 atctttcttt ccttcaggat catccttttg tacttgatct ggaagttttt gtggggaaac
     3181 ttccatactt caccagaaat cctacatgat gagaaagcgc cagttcccgc cgccgcccgg
     3241 tttgcttagt taagtccaca gcagctgttg tgttgaggtg ggagccatgt ttgtttctgc
     3301 taagacactt tccttgactg agctccagca gcaaaggtcc ctcttcccca gccagccctg
     3361 ttgccagtac tacttgaaaa tgtggccact tccagaactc caaacaaaag gaaaataaca
     3421 gaaaaaggca aatcccagga gggagtctcg atgtcccaca catggccgcc actcacgtct
     3481 ccagcacata ccatagagag ctccagcttg gatggctgcc actctgacat cacaacagtg
     3541 cccacagcac ctggaggcgg tccacctcat gtcttcctca atggcttcct gcctgtcact
     3601 cactcagcac aaaagggccc tgggcaggag tgcaggttgc tcacaggtca gtccacgtgg
     3661 cctctagtcc cttgaaagca gcaagaagtg agagaaagca ataactcacc aaagctcaac
     3721 tcccatcctg taccagcctc ccaggatgtc ctttatctgt gtccctcatc ttgccccaga
     3781 cagcagggca ccagggctgc taagaaacca gcctctggac ctcttgcagc agctcaggca
     3841 ccagcttctc tgggcatcgt ggcttcttat caaccatctg ccttgcctct tgccatgcgt
     3901 ctctcccacg tgctcttcca gggaaatcat ggccttgggc ctatgtaggc aacaaagtga
     3961 cttctaaatg acagttgcta gaattcaaag gccagaaaaa gggttgagtt gagccccttc
     4021 cagctccttg tctgatctgt ttcttacagt cttacccact tctcttccac atctgataga
     4081 gacatcagtg gaatccagcc gccttgatca agccctcttg agagtactga ttccatatgc
     4141 aaccctgttt ctggcagctg gcctatgttc tctttgatgc ctggggtcct gagtgctttg
     4201 cttgaggacc aacatgtcta ggagggcggc catgtggcca gtccttgata cctgttttaa
     4261 gtccagcttc ccttcactct ccctggtctc tcagtcatcc ctcttccatg ccttgaggtt
     4321 agtacacatt ctctttccaa agcctctgtg atctgtgcag cctttgcgtg ccaaacttgt
     4381 aagataccat tcacctttcc caggtacctg ctaccaagtc acctggcagc aaccttctgt
     4441 taaggacaga atgggacatt tgcagtcatg agcaggctta cactggttgt gttggcctgc
     4501 agaaatcact aggttagtgg tgtcaaggta tagcacttcg aaacttcttt tcaaggtctc
     4561 caatctccac ctcaaatgac agtggtaaga acactaggcc aatgcagaca gtgttaatgg
     4621 ctgcagcgac cagaggcaac ccatcaggga ttagcaaaga agctgccact gaggcagggg
     4681 ccagaggacc atcaaccaga aggcagactg ctggcagtgt cttatgccag cctcagggaa
     4741 agactaagca gctcagtttc tgcttcagtg catggacacc tgaagttgct agaacacctt
     4801 catgaaagat agccaaaaca ggaaagcttg cttgtgagcc agcttgctgt gtggtctgac
     4861 caagtgagaa agacagcagg cacccaggcc tcagacactc tgacctagct ccagaaagat
     4921 ggccacagcc cagctccctg gtaccaagct gtcatcccta aacttggccc tttgtccctt
     4981 gtgggcagat gctcctcaag cactggcctt tgtgtggggc ccctccctcc ctggagaacg
     5041 ttaaaaggtc ttactctcca cccatcccta cacctgtttt cataagttat gcacaaatgt
     5101 caacagctga gacggggtgg gacaagttct tcattttgct ctttattaag tcaaatatta
     5161 tggaaatatc tacttattag cacccaagac aaatagggga aaggtttaga tgtttttgtg
     5221 tttttaagac tataaccacc tgcaactgga ggacagggct gataacgggt ttggccacaa
     5281 aatggaaagc aagcaaaatc agacctcgta aggggagtat cacacacagt cacgactact
     5341 tcccagagcc aaacgagaag tccctgaact agaagtgcca ttcaaagaat ctcgtgacca
     5401 tcacacaccc agcccctggg tggcacatgg gttgagggag gcccacactt caactcctcc
     5461 ctgttctgaa tgacaccacc tcactctaat gtattgtgtg tgttttagag aaacaatatg
     5521 gtgtgttgtg tctagtgagg aacgcctccc tacctctgtc ctttctgcaa cccaaccatg
     5581 cgtgcttttc ctctaagagc cgcgtgactg tacgtgttga agggggcggt acctgttcac
     5641 agcacaagtt tatgttgagc tctgaactgt cattcacagc tgcgtgtctg catggtgtcg
     5701 catctgttgt acctttgggg aaaatttgta tgtaaatgta cagaaataaa aatgttgccc
     5761 cattaacaga tttcctctgg aatgtcttcc ctacctcacc tgatggtatc cacaaagggc
     5821 atttcactac cactgaggac gagtaagaaa atcctccacg ttgatcagac ctccccacgt
     5881 cactactttc aaggcttctt ctgtgagcgg ccttcattcg ccctgcagat ggtggggcct
     5941 ctcactctgc tttaagagtc ctagtcttaa aaggtagtca gaggctgaga tcggattaaa
     6001 cttaaatgct tatgtagtgt aattctcaaa accatctgag aatcctgcac atttaagatg
     6061 aatttttttc cctcctttgt gttctgctaa tccgtggcct gaggattcct agagaggaca
     6121 aggaatgact atctacactg tgattctggg aggaaagact gataacacaa aactctcttc
     6181 tctaatgtag tattttttaa caagaaaata atatttcttt aataaagcat ttataccaaa
     6241 ctcttctctc c
//
