LOCUS       NM_001357930            2015 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus solute carrier family 22 (organic cation transporter),
            member 22 (Slc22a22), transcript variant 2, mRNA.
ACCESSION   NM_001357930 XM_006520696
VERSION     NM_001357930.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2015)
  AUTHORS   Shiraya,K., Hirata,T., Hatano,R., Nagamori,S., Wiriyasermkul,P.,
            Jutabha,P., Matsubara,M., Muto,S., Tanaka,H., Asano,S., Anzai,N.,
            Endou,H., Yamada,A., Sakurai,H. and Kanai,Y.
  TITLE     A novel transporter of SLC22 family specifically transports
            prostaglandins and co-localizes with 15-hydroxyprostaglandin
            dehydrogenase in renal proximal tubules
  JOURNAL   J Biol Chem 285 (29), 22141-22151 (2010)
   PUBMED   20448048
  REMARK    GeneRIF: OAT-PG is proposed to be involved in the local PGE(2)
            clearance and metabolism for the inactivation of prostaglandin
            signals in the kidney cortex.
REFERENCE   2  (bases 1 to 2015)
  AUTHORS   Jacobsson,J.A., Haitina,T., Lindblom,J. and Fredriksson,R.
  TITLE     Identification of six putative human transporters with structural
            similarity to the drug transporter SLC22 family
  JOURNAL   Genomics 90 (5), 595-609 (2007)
   PUBMED   17714910
REFERENCE   3  (bases 1 to 2015)
  AUTHORS   Katayama,K., Furuno,A., Akiyama,K., Tsuji,T. and Kunieda,T.
  TITLE     Characterization of chromosomal inversion of the mouse hairy ears
            (Eh) mutation associated with cleft palate
  JOURNAL   Mamm Genome 18 (4), 246-254 (2007)
   PUBMED   17520166
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124678.7 and AC161480.9.
            
            On Nov 10, 2017 this sequence version replaced XM_006520696.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC026439.1, AB520670.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-68                AC124678.7         24253-24320
            69-484              AC124678.7         25726-26141
            485-588             AC124678.7         30234-30337
            589-743             AC124678.7         32785-32939
            744-912             AC124678.7         34159-34327
            913-1036            AC124678.7         35098-35221
            1037-1152           AC161480.9         2197-2312
            1153-1367           AC161480.9         3401-3615
            1368-1476           AC161480.9         5628-5736
            1477-1680           AC161480.9         8149-8352
            1681-2015           AC161480.9         9074-9408
FEATURES             Location/Qualifiers
     source          1..2015
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 23.88 cM"
     gene            1..2015
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg"
                     /note="solute carrier family 22 (organic cation
                     transporter), member 22"
                     /db_xref="GeneID:210463"
                     /db_xref="MGI:MGI:2446114"
     exon            1..68
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg"
                     /inference="alignment:Splign:2.1.0"
     exon            69..484
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg"
                     /inference="alignment:Splign:2.1.0"
     exon            485..588
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg"
                     /inference="alignment:Splign:2.1.0"
     exon            589..743
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg"
                     /inference="alignment:Splign:2.1.0"
     exon            744..912
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1036
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1152
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..1367
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg"
                     /inference="alignment:Splign:2.1.0"
     exon            1368..1476
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg"
                     /inference="alignment:Splign:2.1.0"
     exon            1477..1680
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg"
                     /inference="alignment:Splign:2.1.0"
     exon            1681..2015
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1992..1997
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg"
                     /note="hexamer: AATAAA"
     regulatory      1996..2001
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg"
                     /note="hexamer: AACAAA"
     polyA_site      2012
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg"
                     /note="major polyA site"
     polyA_site      2015
                     /gene="Slc22a22"
                     /gene_synonym="oat-pg"
                     /note="major polyA site"
ORIGIN      
        1 cttttggtaa agagacatag ctattctcta tgtgtgattt ggctgtgtgc aacagaagtc
       61 ctatatagca tttgcaagaa tagccatgga ttttgatgaa attctacatc atgtaggtga
      121 cagtggaaga tttcagattt gtatgatcat ccttctcaac attttatcct tggtgttatc
      181 ccctcatgat gtcctggaga attttacagc agccatccct gctcatcact gtagtataaa
      241 ccttgacaat tcaagatctg aagttagtac tgacatgaac ttaactactg aagatttgat
      301 gaaggtctcc atcccaatgg gcccaaatca gaaacccgag caatgccgac gctttaggta
      361 cacccaatgg caatttttag attccaacat atcaactttt aacagcactg agctagagac
      421 tgagccgtgt ctagatggat ggacatatga ccacagtgtt tttacttcta ccattgtcac
      481 tgagtgggat ttagtatgtg attttcagtc attcaaatac tatgcacaag ccacgtcttt
      541 ggcaggacat ttggtatctt gtcctctatc tggcattatt tctgacaggt ttggaaggaa
      601 gccattgttg atgtattgtt ccctagccta tggggctgtg ggaacctact gtgcctttgc
      661 ccccaatttc tccgtttact gtgttttgag attcctgtta tctgccttcc aaagtactat
      721 tttgatcaac tctcttatcc ttgttttgga agaagcatca gtccagtggc accccacaat
      781 catagtactc agtggactgt tcaacagtat tggccagggt gtacttgggg gactagccta
      841 tgtgatttcg gattggcact tacttcaact tgcatatgcc ttgcccttct tcatcttttt
      901 tgttttgttc tgctgggtgc cagaatcagt ccggtggctc ataatcactg gcaaaacaga
      961 tcaagcatgg aaggaactcc agagaattgc ctccatcaat gggaagaaag gcattgcaca
     1021 aaatctaact actgaggact tgcgatccaa acttaagaaa gatgtgaatt caactggaaa
     1081 gcttttcaga ataaaggaca tctttattaa tcccttgata cgtaaaatag tgctttcgaa
     1141 ttccagttta ctttttgcag aacttttcag ctttgttggc ctcttgttgg atgttcaact
     1201 gttgggaaag aacatgttct tgacccagat ttttctagga gcgatagacg tgcccagtaa
     1261 atcactcaca tattttacaa taagaaatgt aagccgtcgt cctttaattg cttttttgct
     1321 acttacaact ggaagttgta ttaccatcac catattcatc tctgaagaga tgtatgtcct
     1381 gcgtactatt attttcattt tgggaaaagg atgttttgca gctttcactt gtataagcac
     1441 aacctacatc aatgaactct caccagtaga actcaggtca actctaaatg gtgttttttt
     1501 agctgttgtt cgattggcag gggtcctgtc tgcactaaca cttgctacta gaaagtattt
     1561 tgtatatctt cccatgatac tctatggagt cctacccatc gtggcaacaa tcagcatcct
     1621 ctttctgcca gagaccttta accttccaca tactgacatt atcaaggata tggagaaaag
     1681 gaaaagattg atgagcaaaa acatcagtaa aaaagaaggg caagacttct tggaaactac
     1741 cgagtgctaa agagagtcaa gatccacagg gttccatcca tataaagact ctttattctg
     1801 tcctgtaccc tagagacttt acccattgat cagcagttac ggatatattt attaaatgaa
     1861 gctactgcaa aagtaaatct cttagccaat ccgttatata gatgcaagtc ctaaggtttt
     1921 tatcaaatac tggagtacaa tcccctttca taaaaaatgt gagaataaat ctgtgcaaca
     1981 acaacaacaa aaataaacaa aaagaaaaac cacaa
//
