LOCUS       NM_027572               2377 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus solute carrier family 22 (organic cation transporter),
            member 16 (Slc22a16), mRNA.
ACCESSION   NM_027572 XM_125547 XM_899485 XM_907868 XM_920606 XM_994568
            XM_994581
VERSION     NM_027572.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2377)
  AUTHORS   Jepsen,K., Solum,D., Zhou,T., McEvilly,R.J., Kim,H.J., Glass,C.K.,
            Hermanson,O. and Rosenfeld,M.G.
  TITLE     SMRT-mediated repression of an H3K27 demethylase in progression
            from neural stem cell to neuron
  JOURNAL   Nature 450 (7168), 415-419 (2007)
   PUBMED   17928865
REFERENCE   2  (bases 1 to 2377)
  AUTHORS   Kellerer,S., Schreiner,S., Stolt,C.C., Scholz,S., Bosl,M.R. and
            Wegner,M.
  TITLE     Replacement of the Sox10 transcription factor by Sox8 reveals
            incomplete functional equivalence
  JOURNAL   Development 133 (15), 2875-2886 (2006)
   PUBMED   16790476
REFERENCE   3  (bases 1 to 2377)
  AUTHORS   Xu,Q., Wonders,C.P. and Anderson,S.A.
  TITLE     Sonic hedgehog maintains the identity of cortical interneuron
            progenitors in the ventral telencephalon
  JOURNAL   Development 132 (22), 4987-4998 (2005)
   PUBMED   16221724
REFERENCE   4  (bases 1 to 2377)
  AUTHORS   Schuurmans,C., Armant,O., Nieto,M., Stenman,J.M., Britz,O.,
            Klenin,N., Brown,C., Langevin,L.M., Seibt,J., Tang,H.,
            Cunningham,J.M., Dyck,R., Walsh,C., Campbell,K., Polleux,F. and
            Guillemot,F.
  TITLE     Sequential phases of cortical specification involve
            Neurogenin-dependent and -independent pathways
  JOURNAL   EMBO J 23 (14), 2892-2902 (2004)
   PUBMED   15229646
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC100473.1.
            
            On or before Jul 24, 2006 this sequence version replaced
            XM_125547.6, XM_899485.2, XM_920606.2, XM_907868.2, XM_994581.1,
            XM_994568.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC100473.1, DQ164804.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..2377
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 21.99 cM"
     gene            1..2377
                     /gene="Slc22a16"
                     /gene_synonym="4921504E14Rik; CT2; FLIPT2; OCT6; OKB1"
                     /note="solute carrier family 22 (organic cation
                     transporter), member 16"
                     /db_xref="GeneID:70840"
                     /db_xref="MGI:MGI:1918090"
     exon            1..160
                     /gene="Slc22a16"
                     /gene_synonym="4921504E14Rik; CT2; FLIPT2; OCT6; OKB1"
                     /inference="alignment:Splign:2.1.0"
     CDS             108..2057
                     /gene="Slc22a16"
                     /gene_synonym="4921504E14Rik; CT2; FLIPT2; OCT6; OKB1"
                     /note="carnitine transporter 2"
                     /codon_start=1
                     /product="solute carrier family 22 member 16"
                     /protein_id="NP_081848.1"
                     /db_xref="CCDS:CCDS23796.1"
                     /db_xref="GeneID:70840"
                     /db_xref="MGI:MGI:1918090"
                     /translation="MESCNVELIFDHIGHFGRFQIVLYLICAYQSLSCGIHYLSSVFL
                     SIIPEHACKPPGMVRKAVFHNVSAWRLEDILALRSPEHKDHIMVELQDGEIWELTRCS
                     RTWRENTSHLGYEYSGYKHDSPCFDGYVYDQSKWRNSAVRNFNLVCDQKWYARMIQPL
                     IIFGVMLGSITFSYLSDRFGRRMALWCTSIGVFFFGIASLFIFDYLSFMITRFFLVMA
                     SSGYFVVVFVYVMEIIGKKARTWASIHLNTFFAIGAMLVALASYLLKTWWLYQIILCI
                     VTTPFILCCWMLPETPFWLLSEGRYKEAQGTVDTMAVWNKSSSCDLVELLSLDVTRSH
                     NKSPHSIRKHRLADLFHNLDVAKMTLIVWLDWFTANLGYYMFGKEVIRRKENEPLYLL
                     LVGAMEIPAYICLCIWLKRVGRRKTMLLFLLVSSLTCMLHVVMPSDYKTAKRMVALLV
                     KSVISSVFAFIYLYTAELYPTTVRCLAVGSSNMVSHVSSIFIPFTSHFSKVWIFLPQI
                     LFGILAILSGLLSLKLPETQDTPMKSTWETTEQQVPENKDSLGEGPPDSFERWDSSRA
                     LSFAERWGLSRASPDAEKWGSGRVPPDAGKWGAGIAPPVTERGASGRASLEDESGGSG
                     RAPPEKNTEMENEIENMKVSNLGGF"
     exon            161..640
                     /gene="Slc22a16"
                     /gene_synonym="4921504E14Rik; CT2; FLIPT2; OCT6; OKB1"
                     /inference="alignment:Splign:2.1.0"
     exon            641..758
                     /gene="Slc22a16"
                     /gene_synonym="4921504E14Rik; CT2; FLIPT2; OCT6; OKB1"
                     /inference="alignment:Splign:2.1.0"
     exon            759..1290
                     /gene="Slc22a16"
                     /gene_synonym="4921504E14Rik; CT2; FLIPT2; OCT6; OKB1"
                     /inference="alignment:Splign:2.1.0"
     exon            1291..1418
                     /gene="Slc22a16"
                     /gene_synonym="4921504E14Rik; CT2; FLIPT2; OCT6; OKB1"
                     /inference="alignment:Splign:2.1.0"
     exon            1419..1528
                     /gene="Slc22a16"
                     /gene_synonym="4921504E14Rik; CT2; FLIPT2; OCT6; OKB1"
                     /inference="alignment:Splign:2.1.0"
     exon            1529..1628
                     /gene="Slc22a16"
                     /gene_synonym="4921504E14Rik; CT2; FLIPT2; OCT6; OKB1"
                     /inference="alignment:Splign:2.1.0"
     exon            1629..2243
                     /gene="Slc22a16"
                     /gene_synonym="4921504E14Rik; CT2; FLIPT2; OCT6; OKB1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2217..2222
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc22a16"
                     /gene_synonym="4921504E14Rik; CT2; FLIPT2; OCT6; OKB1"
                     /note="hexamer: AATAAA"
     polyA_site      2241
                     /gene="Slc22a16"
                     /gene_synonym="4921504E14Rik; CT2; FLIPT2; OCT6; OKB1"
                     /note="major polyA site"
ORIGIN      
        1 aaggaaggag ggcggcctcc ccagcagggg cacccaaggc cacgggcagg tgaggcgggt
       61 cgggtgcggt gctccaagtc cagggcgctc agcactgcca cccggacatg gagtcctgca
      121 acgtggagct gatttttgac cacataggac acttcggcag gttccagata gtcctgtatc
      181 tgatatgtgc ctaccagagc ctctcttgtg gtatccacta tctgtcttct gtgttcctgt
      241 caattatccc tgagcatgcg tgcaagcccc caggcatggt gcggaaggct gttttccaca
      301 acgtatctgc ttggaggttg gaggacatat tggctctgcg gtcaccagag cacaaagatc
      361 acatcatggt ggagctgcag gatggggaga tctgggaact cacgagatgt agcaggactt
      421 ggagggagaa cacgtcacat ttgggctatg agtacagtgg ttataagcat gacagtcctt
      481 gcttcgatgg ctacgtctat gatcagagca aatggaggaa ttctgcggtg agaaatttca
      541 acctggtctg tgatcagaaa tggtatgcaa gaatgatcca gcccttgatt atatttggcg
      601 tgatgctggg atcaattact tttagctacc tttctgacag atttggaagg cgaatggccc
      661 tgtggtgcac gagcatcggc gtgttcttct ttggaatagc atccctcttt atatttgatt
      721 atctcagctt catgatcaca cgctttttcc ttgtgatggc ctcgagtggc tattttgtgg
      781 tggtctttgt ctatgtaatg gagatcattg gcaaaaaggc tcgcacatgg gcatccatac
      841 atctcaatac cttctttgct attggagcaa tgttggtggc tttggcaagc tatttgttga
      901 aaacgtggtg gctctatcag atcatcctgt gcatcgtgac tacccccttc atcctgtgct
      961 gttggatgct tccagagact cccttttggc tcctctcaga aggaagatac aaggaagcac
     1021 aaggcaccgt ggacaccatg gctgtgtgga ataagtccag ctcctgtgac ctggtagagc
     1081 tcttatcact agatgtgacg aggtcccaca ataaaagccc ccacagcatt aggaagcaca
     1141 ggctagcaga tctgtttcat aacctggatg tcgcaaagat gacccttatc gtttggctgg
     1201 attggttcac ggcgaatttg ggatactaca tgtttggcaa ggaggttatt cggagaaaag
     1261 aaaatgaacc cctttacctc ctcctagtgg gtgctatgga aatccctgcc tacatctgtc
     1321 tgtgcatctg gttgaagagg gtgggaagaa gaaagactat gctcctcttc ctcttggtgt
     1381 cctcgctcac ctgtatgctg catgtggtga tgccctcgga ttacaagact gcgaaaagga
     1441 tggtagcttt acttgtcaag agtgttataa gttccgtatt tgcctttatt tatctttata
     1501 cggcggagct gtatccaaca accgtaaggt gcttggctgt agggagcagc aacatggtgt
     1561 cccacgtgtc gagcatcttc atcccattca ccagtcactt ctccaaagtc tggatcttcc
     1621 tgccgcagat tttatttggg atcctggcca tactgagtgg attgttgtca ttgaagcttc
     1681 cagaaaccca ggacacacca atgaaatcta cttgggagac gactgaacag caggtgccag
     1741 aaaacaagga tagtttaggc gaaggccctc ctgatagttt tgagagatgg gattcaagca
     1801 gagccctttc ttttgctgag aggtggggtt taagcagagc ctctcctgat gctgagaagt
     1861 ggggttcagg cagagtccct cctgatgctg ggaagtgggg tgcaggcata gcccctcctg
     1921 tgactgagag gggtgcttca ggcagagctt ctcttgaaga tgagagtggg ggttcaggca
     1981 gagcccctcc tgaaaagaac actgagatgg aaaatgagat agaaaacatg aaagtgagta
     2041 acctgggggg attctgatgg tgataaataa atatcttcca tggtgcccag cacccaggat
     2101 gttggcatca gttactttgt gttagagagg tgttattctt cctttccaca tgttacttat
     2161 gtatctgcat aaaaaatgtg agaaagtatt aaacactgtt ttgtaaaagt aaatgaaata
     2221 aaaccagtat gtgttggaga atgaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     2281 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     2341 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
