LOCUS       NM_011394               3658 bp    mRNA    linear   ROD 10-MAR-2023
DEFINITION  Mus musculus solute carrier family 20, member 2 (Slc20a2), mRNA.
ACCESSION   NM_011394
VERSION     NM_011394.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3658)
  AUTHORS   Zhang Y, Ren Y, Zhang Y, Li Y, Xu C, Peng Z, Jia Y, Qiao S, Zhang Z
            and Shi L.
  TITLE     T-cell infiltration in the central nervous system and their
            association with brain calcification in Slc20a2-deficient mice
  JOURNAL   Front Mol Neurosci 16, 1073723 (2023)
   PUBMED   36741925
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3658)
  AUTHORS   Frangi G, Guicheteau M, Jacquot F, Pyka G, Kerckhofs G, Feyeux M,
            Veziers J, Guihard P, Halgand B, Sourice S, Guicheux J, Prieur X,
            Beck L and Beck-Cormier S.
  TITLE     PiT2 deficiency prevents increase of bone marrow adipose tissue
            during skeletal maturation but not in OVX-induced osteoporosis
  JOURNAL   Front Endocrinol (Lausanne) 13, 921073 (2022)
   PUBMED   36465661
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3658)
  AUTHORS   Ren Y, Shen Y, Si N, Fan S, Zhang Y, Xu W, Shi L and Zhang X.
  TITLE     Slc20a2-Deficient Mice Exhibit Multisystem Abnormalities and
            Impaired Spatial Learning Memory and Sensorimotor Gating but Normal
            Motor Coordination Abilities
  JOURNAL   Front Genet 12, 639935 (2021)
   PUBMED   33889180
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3658)
  AUTHORS   Pastor-Arroyo EM, Knopfel T, Imenez Silva PH, Schnitzbauer U,
            Poncet N, Biber J, Wagner CA and Hernando N.
  TITLE     Intestinal epithelial ablation of Pit-2/Slc20a2 in mice leads to
            sustained elevation of vitamin D3 upon dietary restriction of
            phosphate
  JOURNAL   Acta Physiol (Oxf) 230 (2), e13526 (2020)
   PUBMED   32564464
REFERENCE   5  (bases 1 to 3658)
  AUTHORS   Chande S, Caballero D, Ho BB, Fetene J, Serna J, Pesta D, Nasiri A,
            Jurczak M, Chavkin NW, Hernando N, Giachelli CM, Wagner CA, Zeiss
            C, Shulman GI and Bergwitz C.
  TITLE     Slc20a1/Pit1 and Slc20a2/Pit2 are essential for normal skeletal
            myofiber function and survival
  JOURNAL   Sci Rep 10 (1), 3069 (2020)
   PUBMED   32080237
  REMARK    GeneRIF: Slc20a1/Pit1 and Slc20a2/Pit2 are essential for normal
            skeletal myofiber function and survival.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3658)
  AUTHORS   Filie JD, Burbelo PD and Kozak CA.
  TITLE     Genetic mapping of the alpha 1 and alpha 2 (IV) collagen genes to
            mouse chromosome 8
  JOURNAL   Mamm Genome 6 (7), 487 (1995)
   PUBMED   7579895
REFERENCE   7  (bases 1 to 3658)
  AUTHORS   Miller DG and Miller AD.
  TITLE     A family of retroviruses that utilize related phosphate
            transporters for cell entry
  JOURNAL   J Virol 68 (12), 8270-8276 (1994)
   PUBMED   7966619
REFERENCE   8  (bases 1 to 3658)
  AUTHORS   Lyu MS and Kozak CA.
  TITLE     Genetic mapping of the amphotropic murine leukemia virus receptor
            on mouse chromosome 8
  JOURNAL   Virology 204 (2), 868-869 (1994)
   PUBMED   7941361
REFERENCE   9  (bases 1 to 3658)
  AUTHORS   Garcia JV, Jones C and Miller AD.
  TITLE     Localization of the amphotropic murine leukemia virus receptor gene
            to the pericentromeric region of human chromosome 8
  JOURNAL   J Virol 65 (11), 6316-6319 (1991)
   PUBMED   1656098
REFERENCE   10 (bases 1 to 3658)
  AUTHORS   Gazdar,A.F., Oie,H., Lalley,P., Moss,W.W. and Minna,J.D.
  TITLE     Identification of mouse chromosomes required for murine leukemia
            virus replication
  JOURNAL   Cell 11 (4), 949-956 (1977)
   PUBMED   196770
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CX633041.1, BY237432.1, BY011867.1, BC094562.1 and CF949043.1.
            
            [WARNING] On Oct 16, 2023 this sequence was replaced by
            NM_011394.4.
            
            On Jan 16, 2008 this sequence version replaced NM_011394.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660817.259700.1,
                                           SRR1660811.207002.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-49                CX633041.1         79-127              c
            50-58               BY237432.1         29-37
            59-439              BY011867.1         5-385
            440-1681            BC094562.1         820-2061
            1682-1683           CF949043.1         473-474
            1684-3658           BC094562.1         2064-4038
FEATURES             Location/Qualifiers
     source          1..3658
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 11.42 cM"
     gene            1..3658
                     /gene="Slc20a2"
                     /gene_synonym="MolPit2; Pit-2; Pit2; Ram-1; Ram1"
                     /note="solute carrier family 20, member 2"
                     /db_xref="GeneID:20516"
                     /db_xref="MGI:MGI:97851"
     exon            1..226
                     /gene="Slc20a2"
                     /gene_synonym="MolPit2; Pit-2; Pit2; Ram-1; Ram1"
                     /inference="alignment:Splign:2.1.0"
     exon            227..780
                     /gene="Slc20a2"
                     /gene_synonym="MolPit2; Pit-2; Pit2; Ram-1; Ram1"
                     /inference="alignment:Splign:2.1.0"
     CDS             492..2462
                     /gene="Slc20a2"
                     /gene_synonym="MolPit2; Pit-2; Pit2; Ram-1; Ram1"
                     /note="sodium-dependent phosphate transporter 2; type III
                     sodium-dependent phosphate transporter"
                     /codon_start=1
                     /product="sodium-dependent phosphate transporter 2
                     precursor"
                     /protein_id="NP_035524.2"
                     /db_xref="CCDS:CCDS22178.1"
                     /db_xref="GeneID:20516"
                     /db_xref="MGI:MGI:97851"
                     /translation="MAMDGYLWMVILGFIIAFILAFSVGANDVANSFGTAVGSGVVTL
                     RQACILASIFETTGSVLLGAKVGETIRKGIIDVNLYNETVETLMAGEVSAMVGSAVWQ
                     LIASFLRLPISGTHCIVGSTIGFSLVAIGPKGVQWMELVKIVASWFISPLLSGFMSGV
                     LFILIRMFILTKEDPVPNGLQALPLFYAATIAINVFSIMYTGAPVLGLSLPIWAIALI
                     SFGVALLFAFFVWLFVCPWMKRKIAGRLEKESALSRASDESLRKVQEAESPGFKELPG
                     AKPSDDSAVPLTSLAGEAVGASEGTSAGNHPRASYGRALSMTHGSAKSPISNGTFGFE
                     GHMRNDGHVYHTVHKDSGLYKDLLHKIHVDRGSEEKPTQENNYRLLRRNNSYTCYTAA
                     ICGMPVHTTFRASDTSSAPEDSEKLVGDSVSYSKKRLRYDSYSSYCNAVAEAEIEAEE
                     GGVEMRLASELADPDRPHEDPTEEEKEEKDSAEVHLLFHFLQVLTACFGSFAHGGNDV
                     SNAIGPLVALWLIYQQGGVTQEAATPVWLLFYGGVGICTGLWVWGRRVIQTMGKDLTP
                     ITPSSGFTIELASAFTVVIASNIGLPVSTTHCKVGSVVAVGWIRSRKAVDWRLFRNIF
                     VAWFVTVPVAGLFSAAIMALLMYICGLFSSSR"
     exon            781..921
                     /gene="Slc20a2"
                     /gene_synonym="MolPit2; Pit-2; Pit2; Ram-1; Ram1"
                     /inference="alignment:Splign:2.1.0"
     exon            922..1007
                     /gene="Slc20a2"
                     /gene_synonym="MolPit2; Pit-2; Pit2; Ram-1; Ram1"
                     /inference="alignment:Splign:2.1.0"
     exon            1008..1104
                     /gene="Slc20a2"
                     /gene_synonym="MolPit2; Pit-2; Pit2; Ram-1; Ram1"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1221
                     /gene="Slc20a2"
                     /gene_synonym="MolPit2; Pit-2; Pit2; Ram-1; Ram1"
                     /inference="alignment:Splign:2.1.0"
     exon            1222..1425
                     /gene="Slc20a2"
                     /gene_synonym="MolPit2; Pit-2; Pit2; Ram-1; Ram1"
                     /inference="alignment:Splign:2.1.0"
     exon            1426..2017
                     /gene="Slc20a2"
                     /gene_synonym="MolPit2; Pit-2; Pit2; Ram-1; Ram1"
                     /inference="alignment:Splign:2.1.0"
     exon            2018..2203
                     /gene="Slc20a2"
                     /gene_synonym="MolPit2; Pit-2; Pit2; Ram-1; Ram1"
                     /inference="alignment:Splign:2.1.0"
     exon            2204..2288
                     /gene="Slc20a2"
                     /gene_synonym="MolPit2; Pit-2; Pit2; Ram-1; Ram1"
                     /inference="alignment:Splign:2.1.0"
     exon            2289..3658
                     /gene="Slc20a2"
                     /gene_synonym="MolPit2; Pit-2; Pit2; Ram-1; Ram1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggcggtga cgcagccgcg cgcgggcggg cgagcgagcg ggagagcggg cgggcgggcg
       61 ctcggcggct gctgaggtgc ggaggccgcc gcgccgagcc gctccgctcc gctcgggctg
      121 ttccgggagt cgggcgggga gcgcgggccg agacccagcg gaccggacga cctcgccttc
      181 gtcacttcct gccggcccgc ggtttccgga gggaacgaga agccagaaag aaagatcaca
      241 gctttcccag cctgggagaa aaactatgga atgcggtgta ccactgactg accgtaacca
      301 aacgaactgt accgacagta gtttgaaagc cagcagttag cagtttcttc agacttcaac
      361 actgtccagc gctttccaga gcagactcac tgtttacaag aactcttggc ctcccgaagt
      421 tagcaacctc agattttgtt tatttaaaga atttctgtga aagaaaagga ccccagagcc
      481 cattttccaa aatggccatg gacgggtatc tgtggatggt cattttgggt ttcattattg
      541 ctttcatcct ggcgttttca gtcggtgcca acgatgttgc caattccttc ggaaccgcgg
      601 tgggctctgg cgtggtgacc ctgagacagg catgcattct ggcttccata tttgaaacca
      661 ctggctctgt gctgctgggg gcgaaggtgg gggagaccat tcggaaaggc atcattgacg
      721 tgaatctcta caacgagacc gtggaaacgc taatggctgg ggaagtgagc gccatggttg
      781 gttcagctgt ctggcagttg atcgcgtcct tcctgagact gccaatctcg gggactcact
      841 gcatcgtcgg ctccaccatc ggcttctcac tcgtggcgat tggcccgaaa ggagtgcagt
      901 ggatggagct cgtcaagatt gtcgcctcct ggtttatatc gccacttctt tctggcttca
      961 tgtccggcgt gctgttcata ctaatcagaa tgttcatcct tactaaggag gaccctgttc
     1021 caaacggtct ccaggcactg cctctgtttt atgctgctac catagcaata aatgtctttt
     1081 ccatcatgta cacaggagcg ccagtgctgg gcctgtcgct ccccatctgg gcaatagcgc
     1141 tcatatcctt cggcgttgct ctgctgttcg ccttcttcgt gtggctattc gtgtgtccat
     1201 ggatgaagag gaagatagca ggcagattag agaaggagag cgctctgtcc cgcgcttccg
     1261 atgaaagcct caggaaagta caggaagctg agtcccctgg cttcaaggag ctccctggtg
     1321 ccaaacccag cgatgacagc gctgtccccc tcaccagcct ggctggggag gccgtggggg
     1381 cctcagaagg cacgtcagca gggaaccacc cccgggcttc ctatggacgg gcactttcca
     1441 tgactcacgg ctctgccaag tcacccatct ccaatggtac atttggcttt gaaggccaca
     1501 tgaggaatga cggtcacgtt tatcatactg tacacaaaga ctcggggctc tacaaagact
     1561 tgctgcacaa aatccacgta gacaggggct ccgaggagaa acccactcag gaaaacaact
     1621 acaggctgct tcggaggaac aacagttaca cctgctacac tgcggccatc tgcggcatgc
     1681 cggtgcacac cactttcaga gcctcggaca cctcctctgc ccccgaggac agtgagaagc
     1741 tggtgggtga cagtgtgtcc tattccaaga agaggctccg ctacgacagc tactccagct
     1801 actgcaacgc agtggctgag gccgagattg aggccgaaga gggtggtgtg gaaatgaggc
     1861 tggcctctga gctggccgac cctgaccggc ctcacgagga ccccacggag gaagagaagg
     1921 aggagaagga ctcggcagag gtccacctgc tcttccactt cctgcaagtc ctcactgcct
     1981 gcttcgggtc cttcgctcac ggtggcaatg acgtgagcaa tgctattggt ccccttgtgg
     2041 ctttgtggct gatatatcaa caaggcggag ttacacaaga agctgctact ccagtctggc
     2101 tgctgtttta cggaggagtt ggcatttgca caggtctctg ggtttggggc agaagagtga
     2161 tccagaccat ggggaaggac ctcacgccca tcacaccgtc cagtggcttc actattgagc
     2221 tggcctctgc cttcaccgtg gtgattgcct ccaacatcgg gcttcctgtc agcaccacgc
     2281 actgcaaggt gggctccgtg gtagctgtgg gctggatccg ctcgcggaag gctgtggact
     2341 ggcgcctctt ccggaacatt tttgttgcct ggttcgtgac tgtgcccgtg gctggactct
     2401 tcagtgctgc tatcatggct ctcctcatgt acatatgtgg tctcttttct tccagtcggt
     2461 agacggctgg agggatgttc tgacgtggct aagatactca cacctcccac ccttgctttc
     2521 cctgacacat gcacaccctt ccacacgcct tccagatggc ttcgtgccgg ccctgcttac
     2581 ccaggccaca gctcatcttc cagaattaac ctacctactg tacatagtag catacatcga
     2641 gctgatgctg tgatggcatg atgtggtgcg gttacttaca gtagatgtgt attgtgtacc
     2701 tagaataggt agcatttatc tccagcaaac taagaacgaa agcagaggca ttgcctagac
     2761 cgcaagactc tgttaattgt atataatgat ttcagtggtg gcaagtgtag agtataaaat
     2821 ccttttttaa atacactgta atataagtga gatacagtat acttaatgca aacctgggcg
     2881 agtgcccagg cccttgagtg actgcacaac cctgggacag gtgttcacaa gtgctctctc
     2941 tgaagaatgc gctcctgagc tgggtctgag ttactgtcat gtgtcacaat ggcttcaacg
     3001 gtaaactcaa actactttta accgtctgct tcctgtacac ctttttgatt ggagaaactt
     3061 ggaaagtacc aaagaaatag gggataacgt gccagtgttg catcttccca ttgcttgtcc
     3121 cctccccacg ggccacgaca gtgaacctgg tgacaccagc agcagccagg tggctgccac
     3181 accaggtact ggtaagcttg ttcagcggcc tttccctgtc accagcgtgg atggcgtacg
     3241 gcagtggggg tgtagagttg tacactacat acatatcaag tcccactcgg tgtccctccc
     3301 cgccgtgccc tgcaacctga aaagcagaat ccttgttgcc agcatcagag ccagtgagcg
     3361 cttgatgggc tcggatgctg caagttcacg gttagtggga ggcactggcg aggacactgg
     3421 gcttggggat cttagaggcc ttttctctgt aggacatccg aggttctcct gtggagccgc
     3481 tgttctcttc tgacggtggg agagagtcag gatgactaaa atgttaaggg cccgaaacca
     3541 tggaaatgct gctaatattt ttatattgac atacattttc acggtacttc attgtaattt
     3601 ttttcattaa tcaagcatat taaatttata ataaaaaaaa gtgcccctca aaaactta
//
