LOCUS       NM_182993               3011 bp    mRNA    linear   ROD 18-MAR-2025
DEFINITION  Mus musculus solute carrier family 17 (sodium-dependent inorganic
            phosphate cotransporter), member 7 (Slc17a7), mRNA.
ACCESSION   NM_182993
VERSION     NM_182993.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3011)
  AUTHORS   Liu,Q., Xiong,J., Kim,D.W., Lee,S.S., Bell,B.J., Alexandre,C.,
            Blackshaw,S., Latremoliere,A. and Wu,M.N.
  TITLE     An amygdalar oscillator coordinates cellular and behavioral rhythms
  JOURNAL   Neuron 112 (22), 3750-3767 (2024)
   PUBMED   39303704
REFERENCE   2  (bases 1 to 3011)
  AUTHORS   Parvathy,S., Basu,B., Surya,S., Jose,R., Meera,V., Riya,P.A.,
            Jyothi,N.P., Sanalkumar,R., Praz,V., Riggi,N., Nair,B.S.,
            Gulia,K.K., Kumar,M., Binukumar,B.K. and James,J.
  TITLE     TLX3 regulates CGN progenitor proliferation during cerebellum
            development and its dysfunction can lead to autism
  JOURNAL   iScience 27 (12), 111260 (2024)
   PUBMED   39628587
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3011)
  AUTHORS   Pratelli,M., Hakimi,A.M., Thaker,A., Jang,H., Li,H.Q.,
            Godavarthi,S.K., Lim,B.K. and Spitzer,N.C.
  TITLE     Drug-induced change in transmitter identity is a shared mechanism
            generating cognitive deficits
  JOURNAL   Nat Commun 15 (1), 8260 (2024)
   PUBMED   39327428
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3011)
  AUTHORS   Zhang,L., Nagel,M., Olson,W.P., Chesler,A.T. and O'Connor,D.H.
  TITLE     Trigeminal innervation and tactile responses in mouse tongue
  JOURNAL   Cell Rep 43 (9), 114665 (2024)
   PUBMED   39215998
REFERENCE   5  (bases 1 to 3011)
  AUTHORS   Chang,Y., Lusk,S., Chang,A., Ward,C.S. and Ray,R.S.
  TITLE     Vglut2-based glutamatergic signaling in central noradrenergic
            neurons is dispensable for normal breathing and chemosensory
            reflexes
  JOURNAL   Elife 12, 88673 (2024)
   PUBMED   39287624
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3011)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   7  (bases 1 to 3011)
  AUTHORS   Schuurmans,C., Armant,O., Nieto,M., Stenman,J.M., Britz,O.,
            Klenin,N., Brown,C., Langevin,L.M., Seibt,J., Tang,H.,
            Cunningham,J.M., Dyck,R., Walsh,C., Campbell,K., Polleux,F. and
            Guillemot,F.
  TITLE     Sequential phases of cortical specification involve
            Neurogenin-dependent and -independent pathways
  JOURNAL   EMBO J 23 (14), 2892-2902 (2004)
   PUBMED   15229646
REFERENCE   8  (bases 1 to 3011)
  AUTHORS   Fremeau,R.T. Jr., Kam,K., Qureshi,T., Johnson,J., Copenhagen,D.R.,
            Storm-Mathisen,J., Chaudhry,F.A., Nicoll,R.A. and Edwards,R.H.
  TITLE     Vesicular glutamate transporters 1 and 2 target to functionally
            distinct synaptic release sites
  JOURNAL   Science 304 (5678), 1815-1819 (2004)
   PUBMED   15118123
  REMARK    GeneRIF: developing hippocampal neurons transiently coexpressed
            VGLUT2 and VGLUT1 at distinct synaptic sites with different
            short-term plasticity; the loss of VGLUT1 reduced the reserve pool
            of synaptic vesicles [vglut1]
REFERENCE   9  (bases 1 to 3011)
  AUTHORS   Wojcik,S.M., Rhee,J.S., Herzog,E., Sigler,A., Jahn,R., Takamori,S.,
            Brose,N. and Rosenmund,C.
  TITLE     An essential role for vesicular glutamate transporter 1 (VGLUT1) in
            postnatal development and control of quantal size
  JOURNAL   Proc Natl Acad Sci U S A 101 (18), 7158-7163 (2004)
   PUBMED   15103023
REFERENCE   10 (bases 1 to 3011)
  AUTHORS   Alvarez,F.J., Villalba,R.M., Zerda,R. and Schneider,S.P.
  TITLE     Vesicular glutamate transporters in the spinal cord, with special
            reference to sensory primary afferent synapses
  JOURNAL   J Comp Neurol 472 (3), 257-280 (2004)
   PUBMED   15065123
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY297164.1, AK159064.1 and BC028989.1.
            
            On Dec 17, 2008 this sequence version replaced NM_182993.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK159064.1, ERR3363658.2386576.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-28                BY297164.1         2-29
            29-1660             AK159064.1         2-1633
            1661-3011           BC028989.1         424-1774
FEATURES             Location/Qualifiers
     source          1..3011
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 29.16 cM"
     gene            1..3011
                     /gene="Slc17a7"
                     /gene_synonym="2900052E22Rik; Vglut1"
                     /note="solute carrier family 17 (sodium-dependent
                     inorganic phosphate cotransporter), member 7"
                     /db_xref="GeneID:72961"
                     /db_xref="MGI:MGI:1920211"
     exon            1..224
                     /gene="Slc17a7"
                     /gene_synonym="2900052E22Rik; Vglut1"
                     /inference="alignment:Splign:2.1.0"
     CDS             163..1845
                     /gene="Slc17a7"
                     /gene_synonym="2900052E22Rik; Vglut1"
                     /note="brain-specific Na(+)-dependent inorganic phosphate
                     cotransporter; solute carrier family 17 member 7"
                     /codon_start=1
                     /product="vesicular glutamate transporter 1"
                     /protein_id="NP_892038.2"
                     /db_xref="CCDS:CCDS52244.1"
                     /db_xref="GeneID:72961"
                     /db_xref="MGI:MGI:1920211"
                     /translation="MEFRQEEFRKLAGRALGRLHRLLEKRQEGAETLELSADGRPVTT
                     HTRDPPVVDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHV
                     VVQKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNML
                     IPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGA
                     VVAMPLAGVLVQYSGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIED
                     AIGESAKLMNPVTKFNTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFG
                     FEISKVGLVSALPHLVMTIIVPIGGQIADFLRSRHIMSTTNVRKLMNCGGFGMEATLL
                     LVVGYSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGM
                     VCPIIVGAMTKHKTREEWQYVFLIASLVHYGGVIFYGVFASGEKQPWAEPEEMSEEKC
                     GFVGHDQLAGSDESEMEDEAEPPGAPPAPPPSYGATHSTVQPPRPPPPVRDY"
     exon            225..477
                     /gene="Slc17a7"
                     /gene_synonym="2900052E22Rik; Vglut1"
                     /inference="alignment:Splign:2.1.0"
     exon            478..596
                     /gene="Slc17a7"
                     /gene_synonym="2900052E22Rik; Vglut1"
                     /inference="alignment:Splign:2.1.0"
     exon            597..711
                     /gene="Slc17a7"
                     /gene_synonym="2900052E22Rik; Vglut1"
                     /inference="alignment:Splign:2.1.0"
     exon            712..799
                     /gene="Slc17a7"
                     /gene_synonym="2900052E22Rik; Vglut1"
                     /inference="alignment:Splign:2.1.0"
     exon            800..886
                     /gene="Slc17a7"
                     /gene_synonym="2900052E22Rik; Vglut1"
                     /inference="alignment:Splign:2.1.0"
     exon            887..1029
                     /gene="Slc17a7"
                     /gene_synonym="2900052E22Rik; Vglut1"
                     /inference="alignment:Splign:2.1.0"
     exon            1030..1179
                     /gene="Slc17a7"
                     /gene_synonym="2900052E22Rik; Vglut1"
                     /inference="alignment:Splign:2.1.0"
     exon            1180..1312
                     /gene="Slc17a7"
                     /gene_synonym="2900052E22Rik; Vglut1"
                     /inference="alignment:Splign:2.1.0"
     exon            1313..1423
                     /gene="Slc17a7"
                     /gene_synonym="2900052E22Rik; Vglut1"
                     /inference="alignment:Splign:2.1.0"
     exon            1424..1551
                     /gene="Slc17a7"
                     /gene_synonym="2900052E22Rik; Vglut1"
                     /inference="alignment:Splign:2.1.0"
     exon            1552..2940
                     /gene="Slc17a7"
                     /gene_synonym="2900052E22Rik; Vglut1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2919..2924
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc17a7"
                     /gene_synonym="2900052E22Rik; Vglut1"
                     /note="hexamer: AATAAA"
     polyA_site      2940
                     /gene="Slc17a7"
                     /gene_synonym="2900052E22Rik; Vglut1"
                     /note="major polyA site"
ORIGIN      
        1 gagtccgcta cagccccggg cagcgggcac tcgcagcctg gttccccccc gagcggagct
       61 gcggggccgg gccgggccgg ggcggacccc gggatcccgg acgcggccgc ccgggcccgc
      121 gggcgggggg attggcaggg gacccgcgtg ggcacagcca ccatggagtt ccggcaggag
      181 gagtttcgga agctggcggg gcgcgccctg gggaggctgc accggttact ggagaagcgg
      241 caggaaggcg cggagacact ggagctgagt gccgacgggc ggccagtgac cacgcacact
      301 cgggacccgc ctgtggtgga ctgcacctgc tttggcctcc ctcgtcgcta catcatcgcc
      361 atcatgagcg gtctgggttt ctgtatcagc tttggcatcc gctgcaacct gggcgtggcc
      421 atcgtgtcca tggtcaacaa cagcacaacc caccgtgggg gccacgtggt ggtgcagaaa
      481 gcccagttca actgggatcc agagactgtc ggcctcatac atggctcctt tttctggggc
      541 tacattgtca ctcagattcc tggaggattt atctgccaaa aattcgcagc caacagggtc
      601 tttggctttg ccattgtggc tacctccacc ctaaacatgt tgatcccttc agcagcccgc
      661 gttcactatg gctgtgtcat cttcgtgagg atccttcagg gattggtgga gggggtcaca
      721 taccctgctt gccatggcat ctggagcaaa tgggcccctc ccttagaacg gagtcggctg
      781 gcaacgacag ccttttgcgg ttcctatgct ggggcggtgg ttgccatgcc cttggctggg
      841 gtccttgtgc agtattcagg atggagttct gtcttctatg tctatggcag cttcgggatc
      901 ttttggtacc tgttctggtt gcttgtctcc tatgagtcac cggcactgca ccccagcatc
      961 tctgaggagg agcgcaaata cattgaggat gccatcgggg agagcgccaa gctcatgaac
     1021 cctgttacga agtttaacac accctggagg cgcttcttta cgtccatgcc cgtctatgcc
     1081 atcatcgttg cgaacttttg ccgcagctgg accttctacc tgctcctcat ctctcagccc
     1141 gcctactttg aagaagtgtt cggctttgag atcagcaagg tggggctggt gtcggcgctg
     1201 cctcaccttg tcatgaccat catcgtaccc attggaggcc agatcgctga ctttttgcgc
     1261 agtcgtcaca taatgtccac taccaacgtg cgaaagctca tgaactgcgg gggtttcggg
     1321 atggaagcca cgctgctgct ggtggtcgga tactcgcact ccaagggcgt ggccatctcc
     1381 ttcctggtcc tggctgtggg cttcagtggc tttgccatct ctgggtttaa cgtgaaccac
     1441 ttggacatcg cccctcgcta tgccagcatc ttgatgggca tttccaatgg cgtgggcaca
     1501 ctgtctggga tggtgtgccc catcatcgtg ggtgcaatga ccaagcacaa gacgcgggag
     1561 gagtggcagt acgtgttcct catagcctcc ctggtgcact acggcggtgt catcttctat
     1621 ggggtctttg cttcgggaga gaagcagccg tgggcagagc cggaggagat gagcgaggag
     1681 aagtgtggct ttgttggcca cgaccagctg gctggcagtg acgaaagtga aatggaggac
     1741 gaggctgagc ccccaggggc gccccccgcg ccgcctccgt cctacggggc cacacacagc
     1801 acagtgcagc ctccgaggcc cccgccccct gtccgggact actgaccacg ggcctcccac
     1861 tgtggggcag tttccaggac ttccactcca tacacctcta gcctgagcgg cagtgtcgag
     1921 gaaccccact cctcccctgc ctcaggctta agatgcaagt cctcccttgt tcccagtgct
     1981 gtccgaccag ccctctttcc ctctcaactg cctcctgcgg ggggtgaagc tgcacactag
     2041 cagtttcaag gatacccaga ctcccctgaa agtcgttctc cgcttgtttc tgcctgtgtg
     2101 ggctcaaatc tcccctttga gggctttatt tggagggaca gttcaacctc ttcctctctt
     2161 gtggttttga ggtttcaccc cttcccccaa gaccccaggg attctcaggc taccccgaga
     2221 ttattcaggt ggtcccctac tcagaagact tcatggtcgt cctctattag tttcaaggct
     2281 cgcctaacca attctacatt tttccaagct ggtttaacct aaccaccaat gccgccgttc
     2341 ccaggactga ttctcaccag cgtttctgag ggaaaatggc ggtttcaagt ccccccaccc
     2401 cccttttctt ccctcgtccc ctcaccagca cactttgccg ggccttgacc ttagcttagt
     2461 acaatcattg tccagggaaa tggccaaaat ggctctgctc accccgtgct ctttttctga
     2521 ctcagttttc aggtctcagt agtggctgcc caaagctatt aattcagcgg ctcgaggcca
     2581 cctcttcctc cccgtggtgg tttcaggatc cccctcgccc cccccccccc aaatccttgc
     2641 actttattct cctgggtggt tccaggccgc cctcggtttc tcagtggcca tttgttgtgt
     2701 gtccctcagg ggctaaatga ttccaaatct ggggtgcttc ccctcataga cacccctctc
     2761 tcaacgtaga aatctgggtg ggggtgaggt gtgtgagaga agttacagaa tcccaggaaa
     2821 gggagcgggg ctgggaggag agggttgttc ctggggcagg gtcgtgtctt ggtgtctgtc
     2881 tctgtgacgt aaatcctgcc ctgccccacc ccactcccaa taaacgctct ggtgtacgga
     2941 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     3001 aaaaaaaaaa a
//
