LOCUS       NM_001170638            1957 bp    mRNA    linear   ROD 06-NOV-2024
DEFINITION  Mus musculus solute carrier family 17 (sodium phosphate), member 1
            (Slc17a1), transcript variant 2, mRNA.
ACCESSION   NM_001170638
VERSION     NM_001170638.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1957)
  AUTHORS   Li,V.L., Xiao,S., Schlosser,P., Scherer,N., Wiggenhorn,A.L.,
            Spaas,J., Tung,A.S., Karoly,E.D., Kottgen,A. and Long,J.Z.
  TITLE     SLC17A1/3 transporters mediate renal excretion of Lac-Phe in mice
            and humans
  JOURNAL   Nat Commun 15 (1), 6895 (2024)
   PUBMED   39134528
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1957)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 1957)
  AUTHORS   Oh,H., Lee,S., Oh,Y., Kim,S., Kim,Y.S., Yang,Y., Choi,W., Yoo,Y.E.,
            Cho,H., Lee,S., Yang,E., Koh,W., Won,W., Kim,R., Lee,C.J., Kim,H.,
            Kang,H., Kim,J.Y., Ku,T., Paik,S.B. and Kim,E.
  TITLE     Kv7/KCNQ potassium channels in cortical hyperexcitability and
            juvenile seizure-related death in Ank2-mutant mice
  JOURNAL   Nat Commun 14 (1), 3547 (2023)
   PUBMED   37321992
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1957)
  AUTHORS   Manuel,M., Tan,K.B., Kozic,Z., Molinek,M., Marcos,T.S.,
            Razak,M.F.A., Dobolyi,D., Dobie,R., Henderson,B.E.P.,
            Henderson,N.C., Chan,W.K., Daw,M.I., Mason,J.O. and Price,D.J.
  TITLE     Pax6 limits the competence of developing cerebral cortical cells to
            respond to inductive intercellular signals
  JOURNAL   PLoS Biol 20 (9), e3001563 (2022)
   PUBMED   36067211
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1957)
  AUTHORS   Nguyen,U.P. and Imamura,F.
  TITLE     Regional differences in mitral cell development in mouse olfactory
            bulb
  JOURNAL   J Comp Neurol 527 (14), 2233-2244 (2019)
   PUBMED   30864157
REFERENCE   6  (bases 1 to 1957)
  AUTHORS   Wakabayashi,S., Shigekawa,M. and Pouyssegur,J.
  TITLE     Molecular physiology of vertebrate Na+/H+ exchangers
  JOURNAL   Physiol Rev 77 (1), 51-74 (1997)
   PUBMED   9016300
  REMARK    Review article
REFERENCE   7  (bases 1 to 1957)
  AUTHORS   Kos,C.H., Tihy,F., Murer,H., Lemieux,N. and Tenenhouse,H.S.
  TITLE     Comparative mapping of Na+-phosphate cotransporter genes, NPT1 and
            NPT2, in human and rabbit
  JOURNAL   Cytogenet Cell Genet 75 (1), 22-24 (1996)
   PUBMED   8995482
REFERENCE   8  (bases 1 to 1957)
  AUTHORS   Cole,T.J., Blendy,J.A., Monaghan,A.P., Krieglstein,K., Schmid,W.,
            Aguzzi,A., Fantuzzi,G., Hummler,E., Unsicker,K. and Schutz,G.
  TITLE     Targeted disruption of the glucocorticoid receptor gene blocks
            adrenergic chromaffin cell development and severely retards lung
            maturation
  JOURNAL   Genes Dev 9 (13), 1608-1621 (1995)
   PUBMED   7628695
REFERENCE   9  (bases 1 to 1957)
  AUTHORS   Chong,S.S., Kozak,C.A., Liu,L., Kristjansson,K., Dunn,S.T.,
            Bourdeau,J.E. and Hughes,M.R.
  TITLE     Cloning, genetic mapping, and expression analysis of a mouse renal
            sodium-dependent phosphate cotransporter
  JOURNAL   Am J Physiol 268 (6 Pt 2), F1038-F1045 (1995)
   PUBMED   7611445
REFERENCE   10 (bases 1 to 1957)
  AUTHORS   Chong,S.S., Kristjansson,K., Zoghbi,H.Y. and Hughes,M.R.
  TITLE     Molecular cloning of the cDNA encoding a human renal sodium
            phosphate transport protein and its assignment to chromosome
            6p21.3-p23
  JOURNAL   Genomics 18 (2), 355-359 (1993)
   PUBMED   8288239
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ065843.1, AA986929.1, AK132800.1, AI663290.1, AK164712.1 and
            AW261800.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Variants 1 and 2 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X77241.1, SRR5189682.113313.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-603               CJ065843.1         2-604
            604-736             AA986929.1         363-495
            737-957             AK132800.1         1378-1598
            958-1215            AI663290.1         206-463
            1216-1924           AK164712.1         1218-1926
            1925-1957           AW261800.1         450-482             c
FEATURES             Location/Qualifiers
     source          1..1957
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 9.97 cM"
     gene            1..1957
                     /gene="Slc17a1"
                     /gene_synonym="NAPI-1; Napi1; Npt1"
                     /note="solute carrier family 17 (sodium phosphate), member
                     1"
                     /db_xref="GeneID:20504"
                     /db_xref="MGI:MGI:103209"
     exon            1..79
                     /gene="Slc17a1"
                     /gene_synonym="NAPI-1; Napi1; Npt1"
                     /inference="alignment:Splign:2.1.0"
     exon            80..148
                     /gene="Slc17a1"
                     /gene_synonym="NAPI-1; Napi1; Npt1"
                     /inference="alignment:Splign:2.1.0"
     exon            149..321
                     /gene="Slc17a1"
                     /gene_synonym="NAPI-1; Napi1; Npt1"
                     /inference="alignment:Splign:2.1.0"
     exon            322..555
                     /gene="Slc17a1"
                     /gene_synonym="NAPI-1; Napi1; Npt1"
                     /inference="alignment:Splign:2.1.0"
     exon            556..643
                     /gene="Slc17a1"
                     /gene_synonym="NAPI-1; Napi1; Npt1"
                     /inference="alignment:Splign:2.1.0"
     exon            644..730
                     /gene="Slc17a1"
                     /gene_synonym="NAPI-1; Napi1; Npt1"
                     /inference="alignment:Splign:2.1.0"
     exon            731..849
                     /gene="Slc17a1"
                     /gene_synonym="NAPI-1; Napi1; Npt1"
                     /inference="alignment:Splign:2.1.0"
     exon            850..1011
                     /gene="Slc17a1"
                     /gene_synonym="NAPI-1; Napi1; Npt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..1144
                     /gene="Slc17a1"
                     /gene_synonym="NAPI-1; Napi1; Npt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1145..1292
                     /gene="Slc17a1"
                     /gene_synonym="NAPI-1; Napi1; Npt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1293..1383
                     /gene="Slc17a1"
                     /gene_synonym="NAPI-1; Napi1; Npt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1384..1520
                     /gene="Slc17a1"
                     /gene_synonym="NAPI-1; Napi1; Npt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1521..1957
                     /gene="Slc17a1"
                     /gene_synonym="NAPI-1; Napi1; Npt1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1913..1918
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc17a1"
                     /gene_synonym="NAPI-1; Napi1; Npt1"
                     /note="hexamer: AACAAA"
     polyA_site      1943
                     /gene="Slc17a1"
                     /gene_synonym="NAPI-1; Napi1; Npt1"
                     /note="major polyA site"
ORIGIN      
        1 agcaagtagg aaaaattcca cactaaagtc gagctaaaag tcttcctgga agaaggaagg
       61 gccgttctgt cttaatcagt ggatggagac caagcccagc aacaagaaga taaatctcaa
      121 atggagaacc agtgcctccc caagaaagtt ccagggttct gttccttccg gtatggactg
      181 gctatccttc tgcacttctg taacattgcc atcatggccc agagagtgtg cctgaacctc
      241 accatggtag ccatggtgaa caacacaggg tcaccccatt tatctaacga atctgtagtg
      301 gagatgttgg acaatgtaaa gaaccctgtg tattcctgga gtcctgatat ccaagggctt
      361 attctcagtt ctgtcttctt tggtatggtc gtggttcagg ctcctgtcgg gtacctatct
      421 ggaatatacc caatgaagag aataattggg tcttcactgt tcctcagctc tttgatgtcc
      481 ttgctcctcc cacctgctgc acaagtcgga gctgctttag tcattgtgtg tcgagtactc
      541 cagggaatag cccagggaac agtgtcaaca ggccagcatg aaatatgggt caaatgggca
      601 cctcccttag aacgaggcag acttacctct atgactctat cagggtttgt aatgggacca
      661 tttattgtcc tgcttgtgag tggcttcatc tgtgatcttc tgggctggcc catggtcttc
      721 tacatctttg gtattgttgg gtgtgttctg agtctttcct ggttctttct attctttgat
      781 gaccccaagg accacccgta tatgagcagc agtgagaagg actacatcat atcctccctc
      841 atgcaacagg ccagctcagg cagacaatcc ctgccaatca aagctatgct taaatctctt
      901 ccactctggg ccattatcct caatagcttt gctttcatat ggtcgaacag tctcctggtt
      961 acatacacgc cgacatttat cagcactgtg cttcatgtta atgttagaga gaatggactg
     1021 ctgtccagcc tcccctatct gcttgcctac atctgtggta tcctagcagg tcagatgtca
     1081 gacttcttcc tgaccaggaa gattttcagc atagttaccg tccggaaact cttcaccaca
     1141 ctagggagtt tctgtcccgt gatcttcatc atgtgcttgc tctacctgag ctacaacttc
     1201 tacagcaccg tcattttcct gacacttgcc aactcaacac ttagcttttc ctactgcgga
     1261 caacttatca atgccttgga tattgctccc agatattatg gatttcttaa ggcagtcaca
     1321 gctttaattg gaatgtttgg gggcctgatt tcttcaactc ttgctgggtt gattcttaat
     1381 caggatccgg aatatgcttg gcataaaatt ttcttcttga tggcaggcat taatgtgaca
     1441 tgcctggttt tctattttct atttgctaaa ggagaaattc aggactgggc taaagaaata
     1501 aaaaccacac gactgtgaag ggaagacatg tgaaaatggc attgataacc tttcactgga
     1561 caagaaagac aacttgagaa aaatcttcta gcctagacta atgtctctga agtgttggac
     1621 tcttcagtga catctctctg tgttttgttt cctttttcta caaaagttag tagaaaaagg
     1681 agaagctgag aagcctgagg tcagcatcct tatagaaaga aagaggatcc ttcatgggac
     1741 tgcagtcctg ggagagtcgt gaacacctgg agacaggtag catgaggctc ctgaacgctc
     1801 agtcgcaccc acttctgtct gagtgattct tttgcactgt gtattgtatg taacaagtta
     1861 tacttctgac tttaaaggag gatttattta tgtcttcctc tatgatctaa taaacaaaca
     1921 taagacaaaa ttttactcta caacttcagg aaaagta
//
