LOCUS       NM_001416062            1680 bp    mRNA    linear   ROD 26-JUN-2024
DEFINITION  Mus musculus solute carrier family 16 (monocarboxylic acid
            transporters), member 11 (Slc16a11), transcript variant 2, mRNA.
ACCESSION   NM_001416062 XM_006532916
VERSION     NM_001416062.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1680)
  AUTHORS   Zhang,D., Deng,W., Jiang,T., Zhao,Y., Bai,D., Tian,Y., Kong,S.,
            Zhang,L., Wang,H., Gao,S. and Lu,Z.
  TITLE     Maternal Ezh1/2 deficiency impairs the function of mitochondria in
            mouse oocytes and early embryos
  JOURNAL   J Cell Physiol 239 (6), e31244 (2024)
   PUBMED   38529784
REFERENCE   2  (bases 1 to 1680)
  AUTHORS   Zhang,T., Qi,Z., Wang,H. and Ding,S.
  TITLE     Adeno-Associated Virus-Mediated Knockdown of SLC16A11 Improves
            Glucose Tolerance and Hepatic Insulin Signaling in High Fat
            Diet-Fed Mice
  JOURNAL   Exp Clin Endocrinol Diabetes 129 (2), 104-111 (2021)
   PUBMED   31185508
  REMARK    GeneRIF: Adeno-Associated Virus-Mediated Knockdown of SLC16A11
            Improves Glucose Tolerance and Hepatic Insulin Signaling in High
            Fat Diet-Fed Mice.
REFERENCE   3  (bases 1 to 1680)
  AUTHORS   Zhao,Y., Feng,Z., Zhang,Y., Sun,Y., Chen,Y., Liu,X., Li,S.,
            Zhou,T., Chen,L., Wei,Y., Ma,D., Lui,K.O., Ying,H., Chen,Y. and
            Ding,Q.
  TITLE     Gain-of-Function Mutations of SLC16A11 Contribute to the
            Pathogenesis of Type 2 Diabetes
  JOURNAL   Cell Rep 26 (4), 884-892 (2019)
   PUBMED   30673611
  REMARK    GeneRIF: Gain-of-Function Mutations of SLC16A11 Contribute to the
            Pathogenesis of Type 2 Diabetes.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL669869.10.
            
            On Jan 11, 2023 this sequence version replaced XM_006532916.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784645.1318056.1,
                                           SRR17784647.85922.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-144               AL669869.10        79563-79706
            145-491             AL669869.10        79808-80154
            492-635             AL669869.10        80397-80540
            636-1403            AL669869.10        80726-81493
            1404-1680           AL669869.10        81579-81855
FEATURES             Location/Qualifiers
     source          1..1680
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 42.99 cM"
     gene            1..1680
                     /gene="Slc16a11"
                     /gene_synonym="MCT 11; MNCb-2717"
                     /note="solute carrier family 16 (monocarboxylic acid
                     transporters), member 11"
                     /db_xref="GeneID:216867"
                     /db_xref="MGI:MGI:2663709"
     exon            1..144
                     /gene="Slc16a11"
                     /gene_synonym="MCT 11; MNCb-2717"
                     /inference="alignment:Splign:2.1.0"
     exon            145..491
                     /gene="Slc16a11"
                     /gene_synonym="MCT 11; MNCb-2717"
                     /inference="alignment:Splign:2.1.0"
     CDS             290..1633
                     /gene="Slc16a11"
                     /gene_synonym="MCT 11; MNCb-2717"
                     /note="novel RNA polymerase Rpb1 C-terminal repeat domain
                     containing protein; solute carrier family 16 member 11"
                     /codon_start=1
                     /product="monocarboxylate transporter 11"
                     /protein_id="NP_001402991.1"
                     /db_xref="GeneID:216867"
                     /db_xref="MGI:MGI:2663709"
                     /translation="MTPKPAGPPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAE
                     HFERSAQDTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFAR
                     SLLHLYLGLGLLAGSGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPAL
                     QFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLALSGDPLAPPRTPLAALGLGLFKRR
                     AFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAALVVAVAAVGDACARLASGWL
                     ADQGWVPLPRLLVVFGSLTGLGVLAMGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAP
                     LVFGVLPGLVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDFSASFLVCSSFI
                     LSGSFIYMGLPRALPSCRPASPPATPPPERGELLPVPQVSLLSAGGTGSIRDTTC"
     exon            492..635
                     /gene="Slc16a11"
                     /gene_synonym="MCT 11; MNCb-2717"
                     /inference="alignment:Splign:2.1.0"
     exon            636..1403
                     /gene="Slc16a11"
                     /gene_synonym="MCT 11; MNCb-2717"
                     /inference="alignment:Splign:2.1.0"
     exon            1404..1680
                     /gene="Slc16a11"
                     /gene_synonym="MCT 11; MNCb-2717"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1661..1666
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc16a11"
                     /gene_synonym="MCT 11; MNCb-2717"
                     /note="hexamer: AATAAA"
     polyA_site      1680
                     /gene="Slc16a11"
                     /gene_synonym="MCT 11; MNCb-2717"
                     /note="major polyA site"
ORIGIN      
        1 gtttactgga gagagcggtc caagttgggc tccatctctg tgctggctag ctgctccgca
       61 gaaccctttc tgcggaaagc gcggagaaaa tccggccgaa cccaccttcg ccctttccct
      121 acccccaacg ccgggagagg tcgggcctgg ttcccgcgcc catgctccgg gcgacgtgcc
      181 ctccctgggc gagcagcccg aggctggatc tcagggacgt cagctcccta gcggaggccc
      241 aggcgtggag acttcattca caggtgtttc cccaccccag cagacggcga tgacccccaa
      301 gccggccgga cccccggacg ggggctgggg ctgggtggtg gcggccgcag cattcgccgt
      361 gaacgggctc tcctacgggc tcttacgctc cctgggcctt gccctccccg acctcgcgga
      421 gcactttgaa cgaagcgccc aggacactgc gtgggtcagc gccctggcct tggccgtgca
      481 gcaggcagcc agcccagtgg gcagcgccct gagcactcgc tggggggcac gccccgtggt
      541 gatggttggg ggagtcctaa cctcgcttgg cttggtcttc tcggctttcg cccgaagcct
      601 cctgcacctc tacctcggcc tgggcctcct cgctggctct ggctgggccc tggtgtttgc
      661 cccagccctg ggtaccctct ctcggtactt ctcccgccgt cgggtcttgg cggtagggtt
      721 ggcgctcacc ggtaatgggg catcctcgct gctcctggca cctgccttgc agttcctcct
      781 tgatactttc ggctggcggg gtgccttgct cctccttggc gctgtcaccc ttcacctcac
      841 accctgtggc gccttgctaa gacctttagc tctctctggt gacccgctgg ccccacctcg
      901 caccccccta gctgcccttg gcctaggtct gttcaagcgc cgggcctttt cagtctttgc
      961 tttgggcacc gccttgatcg ggggcggata cttcgtcccc tacgttcatt tgggtccgca
     1021 tgctttagat caaggcatgg gtggttatgg ggcagcgtta gtggtggctg tcgctgcagt
     1081 gggagatgcc tgtgcccgat tggccagcgg atggctggca gaccagggct gggtgcccct
     1141 tccgaggctt ctggtggtgt ttgggtctct gactgggtta ggggtactag caatgggact
     1201 agtgcccact gtggggacag aggagggttg gggggctcct ctgctggccg ctgctggggc
     1261 ctatgggctg agcgctggga gttatgcccc actggttttc ggtgtgctcc cggggctggt
     1321 gggcattgga ggtgtggtgc aggccacagg gctggtgatg atgctgatga gcctcggggg
     1381 actcctgggc cctcctctgt caggcttcct aagggataag acaggagact tcagtgcctc
     1441 tttcctggtg tgcagctctt tcatcctctc tggcagtttc atctacatgg ggctgcccag
     1501 agccctcccc tcctgccgtc cagcctcacc tccagcaacc cctccaccag agagagggga
     1561 gctgctccca gttccacaag tctccctgct ttccgcaggg ggtactggct ccatccggga
     1621 taccacttgt tgatcatttt cttggttgac ctccttccct aataaagaat ttttatctta
//
