LOCUS       NM_177787               2461 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus solute carrier family 15, member 5 (Slc15a5), mRNA.
ACCESSION   NM_177787
VERSION     NM_177787.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2461)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2461)
  AUTHORS   Gineste,C., De Winter,J.M., Kohl,C., Witt,C.C., Giannesini,B.,
            Brohm,K., Le Fur,Y., Gretz,N., Vilmen,C., Pecchi,E., Jubeau,M.,
            Cozzone,P.J., Stienen,G.J., Granzier,H., Labeit,S.,
            Ottenheijm,C.A., Bendahan,D. and Gondin,J.
  TITLE     In vivo and in vitro investigations of heterozygous nebulin
            knock-out mice disclose a mild skeletal muscle phenotype
  JOURNAL   Neuromuscul Disord 23 (4), 357-369 (2013)
   PUBMED   23375831
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC121849.3 and
            AC132431.3.
            
            On Jan 1, 2010 this sequence version replaced NM_177787.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript and protein alignments including
            human NP_001164269.1 and other Slc15 family members.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849375
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-340               AC121849.3         128906-129245       c
            341-563             AC121849.3         122182-122404       c
            564-733             AC121849.3         104951-105120       c
            734-954             AC121849.3         92709-92929         c
            955-1141            AC121849.3         86224-86410         c
            1142-1324           AC132431.3         4463-4645
            1325-1444           AC132431.3         10373-10492
            1445-1553           AC132431.3         35086-35194
            1554-2461           AC132431.3         38070-38977
FEATURES             Location/Qualifiers
     source          1..2461
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 67.96 cM"
     gene            1..2461
                     /gene="Slc15a5"
                     /gene_synonym="9830102E05Rik"
                     /note="solute carrier family 15, member 5"
                     /db_xref="GeneID:277898"
                     /db_xref="MGI:MGI:3607714"
     CDS             1..1701
                     /gene="Slc15a5"
                     /gene_synonym="9830102E05Rik"
                     /codon_start=1
                     /product="solute carrier family 15 member 5"
                     /protein_id="NP_808455.2"
                     /db_xref="GeneID:277898"
                     /db_xref="MGI:MGI:3607714"
                     /translation="MPITDFIINDEKTPLVLHGGPEQWKTVGPYGCFRVGICLLLVEL
                     CERFTFFEVVCNMIPFCTGRLGSYNHQAAMLNLGFIGTSVLTPVFMGWLADEYFGRNK
                     LMYIALSLHFLGTALLSMLAFPAENFYRGAYPVFNNTSVEEQAGLFHVALLTLCLGTG
                     GIRAVVCPPDMCGSQERESKKPMPFCNWASWSANLNAAVVFLGISSIQPLGSGALGIL
                     LPSLSVFTALVTLYLKHCDLIYRPENRCSLLTIARAFVRALKTRCLPYCHFGRDGSSW
                     LDHAMEKQGGHHSELQEEDTRNISALLPLFSFQILYRTCLLQIPSGYYLQTMNSNRNW
                     GGFSLPIALMNAISLLPLLILPPFMDYFSNCLLPSKRDGPFLSACMIAGNICAASSVA
                     MAGFLEIYRKLAREQSPSGKLFSVSSMACVCLVPQYVLLGVSEVLVNPAVSMVTHRVI
                     PGASMAFLTLSHGSACFAGAMLIKLLYLISEGNWFPNTLDKGNLENFFFVLASLMLLN
                     ILGLWRASWRYCNLNHFNAQRIRGNRCEETLLLTEKSLKFYGSTQGASSSIDLWETAL
                     "
     exon            1..340
                     /gene="Slc15a5"
                     /gene_synonym="9830102E05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            341..563
                     /gene="Slc15a5"
                     /gene_synonym="9830102E05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            564..733
                     /gene="Slc15a5"
                     /gene_synonym="9830102E05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            734..954
                     /gene="Slc15a5"
                     /gene_synonym="9830102E05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            955..1141
                     /gene="Slc15a5"
                     /gene_synonym="9830102E05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1142..1324
                     /gene="Slc15a5"
                     /gene_synonym="9830102E05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1325..1444
                     /gene="Slc15a5"
                     /gene_synonym="9830102E05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1445..1553
                     /gene="Slc15a5"
                     /gene_synonym="9830102E05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1554..2461
                     /gene="Slc15a5"
                     /gene_synonym="9830102E05Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1880..1885
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc15a5"
                     /gene_synonym="9830102E05Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1899
                     /gene="Slc15a5"
                     /gene_synonym="9830102E05Rik"
                     /note="major polyA site"
ORIGIN      
        1 atgcccatta cagacttcat cataaatgat gaaaaaacac ccttagtctt acatggtggc
       61 cctgagcagt ggaagacagt gggcccttat ggatgttttc gagttggaat ctgcttgctt
      121 ctggtggagc tgtgtgagag gttcactttc ttcgaagtcg tctgcaacat gatccccttt
      181 tgcacaggga ggcttggctc ctacaaccac caggcagcca tgctcaactt gggctttatt
      241 ggaacctcag tccttacccc tgtgttcatg ggatggcttg cggatgagta cttcggaagg
      301 aacaaactga tgtacatagc cttatctcta catttcctag gcactgcctt gttatccatg
      361 ctggcttttc cagcggagaa tttctacaga ggcgcttatc ctgtgtttaa caacacgtct
      421 gtggaggaac aggctgggtt gtttcatgta gcactgctga ctctctgcct gggcacagga
      481 ggaataaggg ctgtcgtctg tccgccagat atgtgtggca gtcaggaacg ggaatcaaag
      541 aagccaatgc cattttgtaa ctgggcctcc tggtccgcga acctgaatgc agctgttgtc
      601 tttctgggaa tctcaagcat ccagcccttg gggtccgggg cccttggcat cctgcttcct
      661 tctctgtccg tgttcaccgc cctggtgact ctttacctga agcactgcga cctgatctat
      721 cggccagaga accgttgctc cctcctgacg atcgccaggg cgtttgttag ggccctgaaa
      781 acacgctgcc tgccatactg ccactttggg cgagatggat cgagttggtt agaccatgcc
      841 atggaaaaac aaggtggaca ccacagtgaa ctccaagagg aagacacaag aaacatctct
      901 gcccttttgc ctctcttcag cttccagatc ctgtacagaa cgtgcctcct gcagattcct
      961 tcaggatatt atcttcagac catgaattcc aaccggaact ggggtggatt ttctctgccg
     1021 attgcgctaa tgaacgccat cagccttctg ccgttattaa ttctccctcc ctttatggat
     1081 tacttcagca actgtctact tccctctaag agagatggac cattcctgtc agcgtgcatg
     1141 attgctggta acatttgtgc agcatcctct gtggcaatgg ctggcttcct agaaatatac
     1201 agaaaacttg cccgggagca gtctccttca ggcaaacttt tctctgtttc ctccatggcc
     1261 tgtgtctgtc tggttccaca gtatgtgctg cttggagtat ctgaagtcct ggtaaaccct
     1321 gctgtctcca tggtaactca cagagtcatc ccaggcgctt ccatggcttt tttgacactg
     1381 tcccatggat ctgcctgttt cgcaggggca atgctgatta agttgcttta tctcatctcg
     1441 gaaggcaatt ggtttccaaa cacattagac aaaggcaatc tagagaactt cttcttcgtg
     1501 ctggcatcct tgatgctgct caacatcctg ggactctgga gggcttcatg gagatattgt
     1561 aatctaaatc attttaatgc ccagcgcatc cgtggaaatc gttgtgaaga aactcttctc
     1621 ctcactgaga agtctctgaa gttttatggc agtacacagg gagcatcttc aagtattgat
     1681 ctttgggaga cagccctctg aaactggatt tgattctctt gtgagacccg ttatccacta
     1741 ttttcttctt caatcgaata cttcatacgt ttcactggga aagtcaacat aaagaagagt
     1801 gtactttatt tacaatgaat aattatgatc cttccaataa actatgatga cttttaatga
     1861 tatattatgc tcttgaacta ataaagcgat tttaaagtct tggtgattac tctgtgaccg
     1921 gaaacaatca ttttccatgt tagcgtgtca atcatattgt ataatcatta cagtggttca
     1981 gcagttgaag gtgatatgaa agatttattt ataattttaa tgtcattaga agctaagaaa
     2041 caatatgctt ctacttcttc tttctgtata ttcactaagg ctttattgca ttctaggtat
     2101 tataaaccat aagtaatatg atgtttagat aataaatgtg tatagaattc tgctatattt
     2161 gaccttggca ttctactaaa atatatcttg attaagaaac tttcttcaga atttaaaagc
     2221 aatgttacta aaatagaggt cgtttggttt ggttttattt ggtcttatca ggtttgggac
     2281 aagatctcat agagcccagg ctgccctcaa acttaactat gtagcagagg atgatcaaag
     2341 aagtggaaat acagacagat gcctctctag gccatacaat tattattatt attattattg
     2401 ttgttgttgt tattattatt attattattg aataaagtta atgtcctgtc atctctttat
     2461 c
//
