LOCUS       NM_029415               2001 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus solute carrier family 10 (sodium/bile acid
            cotransporter family), member 6 (Slc10a6), mRNA.
ACCESSION   NM_029415 XM_979964
VERSION     NM_029415.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2001)
  AUTHORS   Bakhaus,K., Bennien,J., Fietz,D., Sanchez-Guijo,A., Hartmann,M.,
            Serafini,R., Love,C.C., Golovko,A., Wudy,S.A., Bergmann,M. and
            Geyer,J.
  TITLE     Sodium-dependent organic anion transporter (Slc10a6-/-) knockout
            mice show normal spermatogenesis and reproduction, but elevated
            serum levels for cholesterol sulfate
  JOURNAL   J Steroid Biochem Mol Biol 179, 45-54 (2018)
   PUBMED   28743544
  REMARK    GeneRIF: Slc10a6 role in the supply of steroids in the testis and
            consequently for spermatogenesis and fertility.
REFERENCE   2  (bases 1 to 2001)
  AUTHORS   Grosser,G., Fietz,D., Gunther,S., Bakhaus,K., Schweigmann,H.,
            Ugele,B., Brehm,R., Petzinger,E., Bergmann,M. and Geyer,J.
  TITLE     Cloning and functional characterization of the mouse
            sodium-dependent organic anion transporter Soat (Slc10a6)
  JOURNAL   J Steroid Biochem Mol Biol 138, 90-99 (2013)
   PUBMED   23562556
REFERENCE   3  (bases 1 to 2001)
  AUTHORS   Gineste,C., De Winter,J.M., Kohl,C., Witt,C.C., Giannesini,B.,
            Brohm,K., Le Fur,Y., Gretz,N., Vilmen,C., Pecchi,E., Jubeau,M.,
            Cozzone,P.J., Stienen,G.J., Granzier,H., Labeit,S.,
            Ottenheijm,C.A., Bendahan,D. and Gondin,J.
  TITLE     In vivo and in vitro investigations of heterozygous nebulin
            knock-out mice disclose a mild skeletal muscle phenotype
  JOURNAL   Neuromuscul Disord 23 (4), 357-369 (2013)
   PUBMED   23375831
REFERENCE   4  (bases 1 to 2001)
  AUTHORS   Bailey,P.J., Klos,J.M., Andersson,E., Karlen,M., Kallstrom,M.,
            Ponjavic,J., Muhr,J., Lenhard,B., Sandelin,A. and Ericson,J.
  TITLE     A global genomic transcriptional code associated with CNS-expressed
            genes
  JOURNAL   Exp Cell Res 312 (16), 3108-3119 (2006)
   PUBMED   16919269
REFERENCE   5  (bases 1 to 2001)
  AUTHORS   Willnow,T., Antignac,C., Brandli,A., Christensen,E., Cox,R.,
            Davidson,D., Davies,J., Devuyst,O., Eichele,G., Hastie,N.,
            Verroust,P., Schedl,A. and Meij,I.
  TITLE     The European renal genome project: an integrated approach towards
            understanding the genetics of kidney development and disease
  JOURNAL   Organogenesis 2 (2), 42-47 (2005)
   PUBMED   19521566
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161169.10.
            
            On Sep 30, 2022 this sequence version replaced NM_029415.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK018423.1, BC127608.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-431               AC161169.10        33998-34428
            432-550             AC161169.10        44810-44928
            551-639             AC161169.10        45565-45653
            640-812             AC161169.10        50742-50914
            813-970             AC161169.10        54146-54303
            971-2001            AC161169.10        56537-57567
FEATURES             Location/Qualifiers
     source          1..2001
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 50.45 cM"
     gene            1..2001
                     /gene="Slc10a6"
                     /gene_synonym="8430417G17Rik; Soat"
                     /note="solute carrier family 10 (sodium/bile acid
                     cotransporter family), member 6"
                     /db_xref="GeneID:75750"
                     /db_xref="MGI:MGI:1923000"
     exon            1..431
                     /gene="Slc10a6"
                     /gene_synonym="8430417G17Rik; Soat"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..1176
                     /gene="Slc10a6"
                     /gene_synonym="8430417G17Rik; Soat"
                     /note="solute carrier family 10 member 6"
                     /codon_start=1
                     /product="sodium-dependent organic anion transporter"
                     /protein_id="NP_083691.1"
                     /db_xref="CCDS:CCDS19477.1"
                     /db_xref="GeneID:75750"
                     /db_xref="MGI:MGI:1923000"
                     /translation="MSTDCAGNSTCPVNSTEEDPPVGMEGHANLKLLFTVLSAVMVGL
                     VMFSFGCSVESQKLWLHLRRPWGIAVGLLSQFGLMPLTAYLLAIGFGLKPFQAIAVLM
                     MGSCPGGTISNVLTFWVDGDMDLSISMTTCSTVAALGMMPLCLYIYTRSWTLTQNLVI
                     PYQSIGITLVSLVVPVASGVYVNYRWPKQATVILKVGAILGGMLLLVVAVTGMVLAKG
                     WNTDVTLLVISCIFPLVGHVTGFLLAFLTHQSWQRCRTISIETGAQNIQLCIAMLQLS
                     FSAEYLVQLLNFALAYGLFQVLHGLLIVAAYQAYKRRQKSKCRRQHPDCPDVCYEKQP
                     RETSAFLDKGDEAAVTLGPVQPEQHHRAAELTSHIPSCE"
     exon            432..550
                     /gene="Slc10a6"
                     /gene_synonym="8430417G17Rik; Soat"
                     /inference="alignment:Splign:2.1.0"
     exon            551..639
                     /gene="Slc10a6"
                     /gene_synonym="8430417G17Rik; Soat"
                     /inference="alignment:Splign:2.1.0"
     exon            640..812
                     /gene="Slc10a6"
                     /gene_synonym="8430417G17Rik; Soat"
                     /inference="alignment:Splign:2.1.0"
     exon            813..970
                     /gene="Slc10a6"
                     /gene_synonym="8430417G17Rik; Soat"
                     /inference="alignment:Splign:2.1.0"
     exon            971..2001
                     /gene="Slc10a6"
                     /gene_synonym="8430417G17Rik; Soat"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1978..1983
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slc10a6"
                     /gene_synonym="8430417G17Rik; Soat"
                     /note="hexamer: ATTAAA"
     polyA_site      2001
                     /gene="Slc10a6"
                     /gene_synonym="8430417G17Rik; Soat"
                     /note="major polyA site"
ORIGIN      
        1 agtgcttgct actcatgttc ctttgtgttc ctgtgttcta attcatgaga ggagatgagc
       61 acagactgtg cgggcaactc cacctgccct gtcaacagta cggaggaaga cccgcccgtg
      121 ggaatggagg gccatgcgaa tctaaagctg ctttttacag tgctctcggc tgtgatggtg
      181 ggtttggtca tgttctcttt tggatgttct gtggagagtc agaagctctg gttgcacctc
      241 agaagaccct ggggcatcgc agtgggcctg ctttcccagt ttggacttat gcctctgaca
      301 gcttatctgt tagccattgg cttcggtctg aaaccattcc aagctattgc tgtcctcatg
      361 atggggagct gccctggggg caccatctct aatgttctca ccttctgggt tgatggagat
      421 atggatctca gcatcagtat gacaacctgt tccacagtgg ccgccctggg aatgatgcct
      481 ctctgcctct acatctacac ccggtcctgg actctgacac agaacctcgt cattccgtat
      541 cagagcatag gaattaccct tgtgtccctg gtggttcctg tggcttctgg cgtctatgtg
      601 aattataggt ggccaaagca agcaacggtc attctcaagg tcggagccat tctgggtggc
      661 atgctcctcc tggtggtggc agttactggc atggtcctgg caaaaggctg gaacacagac
      721 gtcactcttc tggtcatcag ctgcattttc cccttggtcg gccatgtcac aggcttcctg
      781 ctggcattcc tcacccacca atcttggcaa aggtgcagga ccatttccat agagactggc
      841 gctcagaaca tccagctgtg catcgccatg ctgcagctgt ccttctctgc tgagtacctg
      901 gtccagctgc taaactttgc attggcctat ggactcttcc aagtgctgca cgggctgctc
      961 attgtcgcag catatcaggc atacaagagg aggcagaaga gtaaatgcag gagacagcac
     1021 ccggattgcc cagacgtctg ctacgagaag cagcccagag agaccagtgc tttcttggat
     1081 aaaggggatg aggctgccgt aactctgggg ccagtgcagc cagagcagca ccacagggct
     1141 gctgagctga ctagccacat tccttcatgt gaatagtggg aggcacggac cagcttggcc
     1201 ctccatcctc ctccgtggcc agtgaagacc atgtatggtt ggcagaaagc agaggtgtct
     1261 ccccacaaag ctgtcctccc attgtggaat gtaatccaag agggagaatg ccatgcagag
     1321 gagacatcac tcacactgca ggacagagct tcttgacttc aggcaggtgc tctggagaac
     1381 tagagaagag acactaagag aattagcttc ggtggtatga tgcttattct taaggaatca
     1441 agcattgttt aaatttgatt atgtgtgtaa tgcaagcggg ctagctcttt ctcttgagag
     1501 ggacaggtgc cttgaatctc ctaactgtag atatacagga tcgccccaat ctccaaaaca
     1561 ccagagacat acgttcatcc attcaagtat tctgagcacc aaatcaccag aaaagcctgt
     1621 ggcttgtttc ctgtttgttt tcatagctga tcagtgatta tctcagaaca tcttcacaca
     1681 cctgtgttac ctacctcatt ccttagaaca gtggctgctt ccaaatgttg tgtaatgtag
     1741 gactgtaatt tattgaaggc atctttataa gtatttagac atcttccagc gcagggctgc
     1801 tgcgaacccc tggccctgac cccatgtccc cgtaggttct ttcctgcagc tgcagtgggc
     1861 aggcccacag ctcctcagaa tcccggacag attgttcagt ctcagaaggg ctttgctgtt
     1921 cactcccgcc agtcctaaga aatgattgct catcgttttg acttgcgaaa acatctcatt
     1981 aaaattatga tctcaaaatt a
//
