LOCUS       NM_198014               2875 bp    mRNA    linear   ROD 26-NOV-2024
DEFINITION  Mus musculus SLAIN motif family, member 1 (Slain1), transcript
            variant 2, mRNA.
ACCESSION   NM_198014 XM_001006556
VERSION     NM_198014.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2875)
  AUTHORS   Piasecka,A., Szczesniak,M.W., Sekrecki,M., Kajdasz,A.,
            Sznajder,L.J., Baud,A. and Sobczak,K.
  TITLE     MBNL splicing factors regulate the microtranscriptome of skeletal
            muscles
  JOURNAL   Nucleic Acids Res 52 (19), 12055-12073 (2024)
   PUBMED   39258536
REFERENCE   2  (bases 1 to 2875)
  AUTHORS   van der Vaart,B., Franker,M.A., Kuijpers,M., Hua,S., Bouchet,B.P.,
            Jiang,K., Grigoriev,I., Hoogenraad,C.C. and Akhmanova,A.
  TITLE     Microtubule plus-end tracking proteins SLAIN1/2 and ch-TOG promote
            axonal development
  JOURNAL   J Neurosci 32 (42), 14722-14728 (2012)
   PUBMED   23077057
  REMARK    GeneRIF: SLAIN1 is highly enriched in brain and expressed
            throughout brain development.
REFERENCE   3  (bases 1 to 2875)
  AUTHORS   van der Vaart,B., Manatschal,C., Grigoriev,I., Olieric,V.,
            Gouveia,S.M., Bjelic,S., Demmers,J., Vorobjev,I., Hoogenraad,C.C.,
            Steinmetz,M.O. and Akhmanova,A.
  TITLE     SLAIN2 links microtubule plus end-tracking proteins and controls
            microtubule growth in interphase
  JOURNAL   J Cell Biol 193 (6), 1083-1099 (2011)
   PUBMED   21646404
REFERENCE   4  (bases 1 to 2875)
  AUTHORS   Hirst,C.E., Lim,S.M., Pereira,L.A., Mayberry,R.A., Stanley,E.G. and
            Elefanty,A.G.
  TITLE     Expression from a betageo gene trap in the Slain1 gene locus is
            predominantly associated with the developing nervous system
  JOURNAL   Int J Dev Biol 54 (8-9), 1383-1388 (2010)
   PUBMED   20563991
  REMARK    GeneRIF: Data suggest that Slain1 may play a role in the
            development of the nervous system, as well as in the morphogenesis
            of several embryonic structures.
REFERENCE   5  (bases 1 to 2875)
  AUTHORS   Hirst,C.E., Ng,E.S., Azzola,L., Voss,A.K., Thomas,T., Stanley,E.G.
            and Elefanty,A.G.
  TITLE     Transcriptional profiling of mouse and human ES cells identifies
            SLAIN1, a novel stem cell gene
  JOURNAL   Dev Biol 293 (1), 90-103 (2006)
   PUBMED   16546155
  REMARK    GeneRIF: Expressed at the stem cell and epiblast stages of
            embryonic stem cell differentiation and in the epiblast, nervous
            system, tailbud and somites of the developing mouse embryo.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK036190.1, BC079866.1 and BX529670.1.
            
            On Mar 29, 2018 this sequence version replaced NM_198014.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079866.1, SRR1660819.76137.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                AK036190.1         2-16
            16-2758             BC079866.1         1-2743
            2759-2875           BX529670.1         1-117               c
FEATURES             Location/Qualifiers
     source          1..2875
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 52.75 cM"
     gene            1..2875
                     /gene="Slain1"
                     /gene_synonym="9630044O09Rik"
                     /note="SLAIN motif family, member 1"
                     /db_xref="GeneID:105439"
                     /db_xref="MGI:MGI:2145578"
     exon            1..681
                     /gene="Slain1"
                     /gene_synonym="9630044O09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..1867
                     /gene="Slain1"
                     /gene_synonym="9630044O09Rik"
                     /note="isoform 2 is encoded by transcript variant 2; SLAIN
                     motif-containing protein 1"
                     /codon_start=1
                     /product="SLAIN motif-containing protein 1 isoform 2"
                     /protein_id="NP_932131.2"
                     /db_xref="CCDS:CCDS27316.1"
                     /db_xref="GeneID:105439"
                     /db_xref="MGI:MGI:2145578"
                     /translation="MMAEQVKCASPVAASGAGPGPVVNAELEVKKLQELVRKLEKQNE
                     QLRSRAASAAAAPHLLLLQPPPPSAPPPAGACSPLATHRAPASTTSPGPGALGPAFPG
                     TYCLPSPAPSLLCSLQPADAPFVYSKPAAGFFGGGGSPEPGTAGTPPGEAATPPLPPP
                     TLLDEVEPLDLESLAAWSEEDDYTWLYVGSSKTFTSPEKSPSPLQWCRHVLDNPTPEM
                     EAARRSLRFRLEQGYTSRGSPLSPQSSIDSELSTSELEDDSISMGYKLQDLTDVQIMA
                     RLQEESLRQDYASTSASVSRNSSSVSLSSGKKGTCSDQEYDRYSLEDEEEFDHLPPPQ
                     PRLPRCSPFQRGIPHSQTFSSIRDCRRSPSTQYFPSNNFQQPQYYPPQAQTADQQPNR
                     TNGDKLRRSMPNLARMPSTAAASSNLSSPVTVRSSQSFDSSLHGAGSGVSRVPSCIPS
                     PGQIQHRVHSVGHFPVPIRQPLKATAYVSPTVQGSSSSGSSGSSGGSGSGMPLSNGTQ
                     LYSTTGIPTPNKAAASGILGRSALPRPSLAINGSNLPRSKIAQPVRSFLQPPKPLSSL
                     STLRDGNWRDGCY"
     exon            682..821
                     /gene="Slain1"
                     /gene_synonym="9630044O09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            822..971
                     /gene="Slain1"
                     /gene_synonym="9630044O09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1313
                     /gene="Slain1"
                     /gene_synonym="9630044O09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1314..1469
                     /gene="Slain1"
                     /gene_synonym="9630044O09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1470..1791
                     /gene="Slain1"
                     /gene_synonym="9630044O09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1792..2863
                     /gene="Slain1"
                     /gene_synonym="9630044O09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2842..2847
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Slain1"
                     /gene_synonym="9630044O09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2863
                     /gene="Slain1"
                     /gene_synonym="9630044O09Rik"
                     /note="major polyA site"
ORIGIN      
        1 agagcacggt gcagagctgc gcggctgctt cttcctcggc cggaggctgg gccctggtgc
       61 tgatgctggt aggctgcgcg agctgggccc gcgtagcctc ctcgccgcgg cgctcggggc
      121 tcccgcgatg atggcggagc aggtgaaatg cgcctcgccg gtggcggcct ccggcgccgg
      181 cccggggccg gtggtgaacg ccgagctgga ggtgaagaag ctgcaggagc tggtgcgcaa
      241 gctggagaag cagaacgagc agctgcgcag ccgggcggcc agtgcggccg ccgccccgca
      301 cctgctgctg ctgcagccgc cgccgccctc cgccccgccg ccagccgggg cctgcagccc
      361 gctcgccacg cacagggccc cggccagcac gacctccccg ggcccggggg cgctgggccc
      421 cgcgttcccg ggcacctact gcttgcccag ccccgcgccc tccctgctct gcagcctgca
      481 gccggctgac gcgcccttcg tctactccaa gccggcggcg ggcttcttcg gcggaggtgg
      541 cagcccggaa ccggggaccg cagggacccc gccgggggaa gccgccacgc cgccgttgcc
      601 gcctccaacg ctgctggacg aggtggagcc gctggacctg gagagcttgg ccgcctggag
      661 cgaggaggac gactacacct ggttatatgt tggctcttca aagacattca cctcaccaga
      721 gaaatccccg agtcctttgc agtggtgtag acatgtccta gataacccaa ctcctgagat
      781 ggaagcagcc agacgctctc tgcgcttcag actggagcaa ggttatacct ccaggggctc
      841 tccacttagt ccgcagtcat ccatcgacag tgagctgagt acctcggagt tggaggatga
      901 ctctatatcc atgggatata aattacagga ccttactgat gttcagatca tggctcgtct
      961 gcaagaagag agtctcaggc aagactacgc ttccacgtca gcatcagtgt ccagaaacag
     1021 ttccagtgta tccctgagtt cagggaaaaa ggggacatgc agtgatcaag agtatgatcg
     1081 ctacagcctg gaggacgagg aagagtttga ccatctgccg ccaccccagc cccgtcttcc
     1141 gaggtgttca cctttccaaa gagggatccc ccactcacag actttctcca gcatccggga
     1201 ttgcaggagg agccccagta cccagtattt cccctcaaat aacttccagc agccacagta
     1261 ttacccacct caagcccaga ctgcagacca gcaaccaaat aggaccaatg gagataagct
     1321 acgaagaagc atgcctaatc tggcccggat gccgagcacc gctgcggcca gcagcaacct
     1381 cagctctcct gtgacagtga ggagcagtca gagctttgac tccagcttgc atggagctgg
     1441 aagtggggtt tctcgggtac cgtcctgcat cccgtcacca ggacagattc agcacagagt
     1501 tcacagcgtg ggccacttcc cagtgcccat ccggcagccc ctgaaggcca cagcctatgt
     1561 gagcccaact gttcaaggca gcagcagcag cggcagcagt ggtagcagcg gcggcagcgg
     1621 cagcggcatg cctttatcca atggcacgca gttatattcc accacgggca tccctactcc
     1681 gaacaaagct gcggcttctg ggatcctggg tcgcagcgcc cttccgagac cttcactggc
     1741 aataaatggg agtaacctgc ctcggagcaa gattgcacag cctgtcagaa gcttcctgca
     1801 gcctcccaag cctctgtctt cactcagcac actgagggat ggaaattgga gagacggttg
     1861 ctactgatgc agttttacgg acccttgaag aatgggaaga agtgaaaatg agggtgtgtt
     1921 acctagctgg ctgggtaacc atggatgctg ggatgctttc cccttcacgc taaccacacg
     1981 cacggcatcg ttttcagtgg accaatcacc agagactaac gagctcacct actctctgcc
     2041 tgagatactg cggcgttccc aaacccgcgg ccgcggtatc gttaccttag atctaggaag
     2101 tttttgtaga actgctccgt atctgaatac tttttgagag agattgaggc gtatcaataa
     2161 tgctttgcca tatgaggttt ttaaaagtac cttgttcatt ttacctacat gttttaaaca
     2221 ccttccatta catgttctgc attttaatac attgcatatt tacaactagg ttctataaca
     2281 tggtttgaat tttaattttt tatagtttac aggaatttta ttttttgtgc ctatttcttt
     2341 ttatgcctat gtgaaccact atggaacaac ttaaattttg tgccataaaa atatttttgt
     2401 ggtaaggtac tattttttta gctctaggga tatatcagca aaaacacacc atacgatttg
     2461 agacataatt ttacgttgaa cgagcacaat ttaatctaaa gcgttgcaag gagacagcca
     2521 gacggcagag ttaaacggtc ttgtcttttt cattgttaat ttattgtctt acatgagttt
     2581 catatttatg atggtatcac aagctcattg cacttaagac ccgcaatgtt tgctactcaa
     2641 ccacacaatt gattttcaat actttattac aaaggatgaa actgtaatgt tttattaaca
     2701 atgcttctgg aaacgaatgc attttaaata aatctttttg atagaccttt tacaaaaacc
     2761 catttgcact aatgaatgct ttcttagggt ctatgactta ctgtttgtta ctgtgtacac
     2821 tgctgttttg gaatgttcgg aaataaagac tctatttcag caaaaaaaaa aaaaa
//
