LOCUS       NM_001109743            3141 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus SKI family transcriptional corepressor 2 (Skor2),
            mRNA.
ACCESSION   NM_001109743 XM_001478978
VERSION     NM_001109743.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3141)
  AUTHORS   Vermeiren,S., Cabochette,P., Dannawi,M., Desiderio,S., San
            Jose,A.S., Achouri,Y., Kricha,S., Sitte,M., Salinas-Riester,G.,
            Vanhollebeke,B., Brunet,J.F. and Bellefroid,E.J.
  TITLE     Prdm12 represses the expression of the visceral neuron determinants
            Phox2a/b in developing somatosensory ganglia
  JOURNAL   iScience 26 (12), 108364 (2023)
   PUBMED   38025786
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3141)
  AUTHORS   Kirjavainen,A., Singh,P., Lahti,L., Seja,P., Lelkes,Z.,
            Makkonen,A., Kilpinen,S., Ono,Y., Salminen,M., Aitta-Aho,T.,
            Stenberg,T., Molchanova,S., Achim,K. and Partanen,J.
  TITLE     Gata2, Nkx2-2 and Skor2 form a transcription factor network
            regulating development of a midbrain GABAergic neuron subtype with
            characteristics of REM-sleep regulatory neurons
  JOURNAL   Development 149 (14) (2022)
   PUBMED   35815619
REFERENCE   3  (bases 1 to 3141)
  AUTHORS   Hwang,I., Kim,B.S., Ko,H.R., Cho,S., Lee,H.Y., Cho,S.W., Ryu,D.,
            Shim,S. and Ahn,J.Y.
  TITLE     Cerebellar dysfunction and schizophrenia-like behavior in
            Ebp1-deficient mice
  JOURNAL   Mol Psychiatry 27 (4), 2030-2041 (2022)
   PUBMED   35165395
REFERENCE   4  (bases 1 to 3141)
  AUTHORS   Tran-Anh,K., Zhang,J., Nguyen-Minh,V.T., Fujita,H., Hirata,T. and
            Sugihara,I.
  TITLE     Common Origin of the Cerebellar Dual Somatotopic Areas Revealed by
            Tracking Embryonic Purkinje Cell Clusters with Birthdate Tagging
  JOURNAL   eNeuro 7 (6) (2020)
   PUBMED   33055198
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3141)
  AUTHORS   Ma,T.C., Vong,K.I. and Kwan,K.M.
  TITLE     Spatiotemporal Decline of BMP Signaling Activity in Neural
            Progenitors Mediates Fate Transition and Safeguards Neurogenesis
  JOURNAL   Cell Rep 30 (11), 3616-3624 (2020)
   PUBMED   32187534
REFERENCE   6  (bases 1 to 3141)
  AUTHORS   Matsumoto,A., Susaki,E., Onoyama,I., Nakayama,K., Hoshino,M. and
            Nakayama,K.I.
  TITLE     Deregulation of the p57-E2F1-p53 axis results in nonobstructive
            hydrocephalus and cerebellar malformation in mice
  JOURNAL   Mol Cell Biol 31 (20), 4176-4192 (2011)
   PUBMED   21844226
REFERENCE   7  (bases 1 to 3141)
  AUTHORS   Miyata,T., Ono,Y., Okamoto,M., Masaoka,M., Sakakibara,A.,
            Kawaguchi,A., Hashimoto,M. and Ogawa,M.
  TITLE     Migration, early axonogenesis, and Reelin-dependent layer-forming
            behavior of early/posterior-born Purkinje cells in the developing
            mouse lateral cerebellum
  JOURNAL   Neural Dev 5, 23 (2010)
   PUBMED   20809939
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 3141)
  AUTHORS   Mizuhara,E., Minaki,Y., Nakatani,T., Kumai,M., Inoue,T.,
            Muguruma,K., Sasai,Y. and Ono,Y.
  TITLE     Purkinje cells originate from cerebellar ventricular zone
            progenitors positive for Neph3 and E-cadherin
  JOURNAL   Dev Biol 338 (2), 202-214 (2010)
   PUBMED   20004188
REFERENCE   9  (bases 1 to 3141)
  AUTHORS   Minaki,Y., Nakatani,T., Mizuhara,E., Inoue,T. and Ono,Y.
  TITLE     Identification of a novel transcriptional corepressor, Corl2, as a
            cerebellar Purkinje cell-selective marker
  JOURNAL   Gene Expr Patterns 8 (6), 418-423 (2008)
   PUBMED   18522874
  REMARK    GeneRIF: Results strongly suggest that Corl2 is a specific marker
            for Purkinje cells in the cerebellum from their emergence until the
            adult stage.
REFERENCE   10 (bases 1 to 3141)
  AUTHORS   Arndt,S., Poser,I., Schubert,T., Moser,M. and Bosserhoff,A.K.
  TITLE     Cloning and functional characterization of a new Ski homolog,
            Fussel-18, specifically expressed in neuronal tissues
  JOURNAL   Lab Invest 85 (11), 1330-1341 (2005)
   PUBMED   16200078
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB358976.1.
            
            On Oct 5, 2007 this sequence version replaced XM_001478978.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB358976.1, SRR7345562.3081675.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164136, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3141
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 51.93 cM"
     gene            1..3141
                     /gene="Skor2"
                     /gene_synonym="Corl2; EG664805; Fussel18; Gm7348"
                     /note="SKI family transcriptional corepressor 2"
                     /db_xref="GeneID:664805"
                     /db_xref="MGI:MGI:3645984"
     exon            1..34
                     /gene="Skor2"
                     /gene_synonym="Corl2; EG664805; Fussel18; Gm7348"
                     /inference="alignment:Splign:2.1.0"
     exon            35..2682
                     /gene="Skor2"
                     /gene_synonym="Corl2; EG664805; Fussel18; Gm7348"
                     /inference="alignment:Splign:2.1.0"
     CDS             85..3111
                     /gene="Skor2"
                     /gene_synonym="Corl2; EG664805; Fussel18; Gm7348"
                     /note="ladybird homeobox corepressor 1-like protein;
                     transcriptional corepressor Corl2; LBX1 corepressor 1-like
                     protein; fussel-18 homolog; functional Smad suppressor
                     element on chromosome 18"
                     /codon_start=1
                     /product="SKI family transcriptional corepressor 2"
                     /protein_id="NP_001103213.1"
                     /db_xref="CCDS:CCDS50322.1"
                     /db_xref="GeneID:664805"
                     /db_xref="MGI:MGI:3645984"
                     /translation="MASSPLPGPNDILLASPSSAFQPDALSQPRPGHANLKPNQVGQV
                     ILYGIPIVSLVIDGQERLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEIL
                     RRAGAMPISSRRCGMITKREAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFI
                     PARYNSSRAKCIKCSYCNMYFSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDK
                     SPQDELVFAWEDVKAMFNGGSRKRALPQPSAHPACHPLSSVKAAAVAAAAAVAGGGGL
                     LGPHLLGAPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAAS
                     LSVAAATGGAGPGAGGPGGGCVAGVGVGASAGAGAAAGTKGPRSYPVIPVPSKGSFGG
                     VLQKFPGCGGLFPHPYTFPAAAAAFGLCHKKEDAGTAAEALGGAGAGSAGAAPKAGLS
                     GLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGDSPALLRQA
                     FLDLAEPGGAGGSAEAAPPPGQPPPVVANGPGSGPPATGGTGARDTLFESPPGGSGGD
                     CSAGSTPPAEQGVTSGTGSASSGAGSVGTRVPAPHHPHLLEGRKAGGGSYHHSSAFRP
                     VGGKDDAESLAKLHGASAGTPHSAPAHHHHHHHHPHHHHHHPPQPPSPLLLLQPQPDE
                     PGSERHHPAPPPPPPPPPLAPQPHHRGLLSPEGTSCSYPSEDSSEDEEDEEEEQEVDV
                     EGHKPLEGEEEEDGRDPEDEEEEDEETRVLLGDSLVGGGRFLQGRGLSEKGSGRDRTT
                     PAVGAFPLALNSSRLLQEDGKLGDSGGSDLPAPPPPPLAPQKASSSGGSRPGSPVHHP
                     SLEEEPSYKDNQKPKENNQVIISTKDDNFSDKNKGHGFFITDSDSSGDFWRERSGEHT
                     QETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEFQVLKGNTSFPVFNNFQDQM
                     KRELAYREEMVQQLQIIPYAASLIRKEKLGAHLSKS"
     exon            2683..2743
                     /gene="Skor2"
                     /gene_synonym="Corl2; EG664805; Fussel18; Gm7348"
                     /inference="alignment:Splign:2.1.0"
     exon            2744..2815
                     /gene="Skor2"
                     /gene_synonym="Corl2; EG664805; Fussel18; Gm7348"
                     /inference="alignment:Splign:2.1.0"
     exon            2816..2881
                     /gene="Skor2"
                     /gene_synonym="Corl2; EG664805; Fussel18; Gm7348"
                     /inference="alignment:Splign:2.1.0"
     exon            2882..2980
                     /gene="Skor2"
                     /gene_synonym="Corl2; EG664805; Fussel18; Gm7348"
                     /inference="alignment:Splign:2.1.0"
     exon            2981..3048
                     /gene="Skor2"
                     /gene_synonym="Corl2; EG664805; Fussel18; Gm7348"
                     /inference="alignment:Splign:2.1.0"
     exon            3049..3114
                     /gene="Skor2"
                     /gene_synonym="Corl2; EG664805; Fussel18; Gm7348"
                     /inference="alignment:Splign:2.1.0"
     exon            3115..3141
                     /gene="Skor2"
                     /gene_synonym="Corl2; EG664805; Fussel18; Gm7348"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agctacaagc ctaaagacgt caagggctta ccagtctcca aggcaaaccc ggagctctaa
       61 gcccgctgtt cttccgtgga ggagatggct tccagcccac tgccagggcc caatgatatc
      121 ctacttgcat cgccatcgag cgccttccag cccgacgcat tgagccaacc gcggccgggt
      181 cacgccaacc ttaaacccaa ccaggtgggc caggtgatcc tctatggcat tcccatcgtg
      241 tccttggtga tcgacgggca ggagcgcctg tgcctggcgc agatctccaa cactcttctc
      301 aagaacttca gctataacga gatccacaac cgccgagtgg ctctgggcat cacgtgcgtg
      361 cagtgcacac ctgtccaact ggagatcctg cggcgggccg gggccatgcc catctcttcg
      421 cggcgttgtg gcatgatcac caagcgtgag gccgagcgcc tttgtaagtc attcctgggc
      481 gaaaatcggc cacccaagct gccggacaac ttcgccttcg acgtgtcgca cgagtgtgcc
      541 tggggctgcc gcggcagctt catcccggcg cgctacaaca gctctcgcgc caagtgcatc
      601 aagtgtagct actgcaacat gtacttctcc cccaacaagt tcattttcca ctcccaccgc
      661 accccagacg ccaagtacac acagccagac gcggctaact tcaattcctg gcgccgccat
      721 ctcaagctca cagacaagag ccctcaggac gagctagtct tcgcctggga ggacgtcaag
      781 gccatgttca acggtggcag ccgcaagcgc gcgctacctc aacccagcgc gcacccggcc
      841 tgtcacccac tcagttccgt caaggctgct gcggtggcgg ccgcagccgc agtggccggg
      901 ggcggaggcc tgctgggccc gcacctgctg ggggctccac ccccgccacc gccgccacca
      961 cccttggctg agctggcggg cgcacctcac gcccatcaca agcggccgcg cttcgacgac
     1021 gatgacgatt ccctccagga agctgccgtg gtggctgcag ccagcctctc ggcagccgca
     1081 gccagcctct cggtggccgc agccacaggc ggcgccgggc caggcgcagg tggccccggg
     1141 ggtggctgcg tggccggcgt gggcgtgggt gccagtgcgg gggctggtgc agcagctggc
     1201 accaaaggtc cacgcagcta cccagtcatc ccagtgccca gcaagggttc gttcgggggc
     1261 gtgctacaga agttcccggg ctgcgggggc ctcttcccgc atccttacac cttcccggca
     1321 gcggccgcag ccttcggctt gtgccacaag aaggaggacg cggggacagc ggccgaggcc
     1381 ctggggggag cgggcgcggg gagcgcaggt gcggcgccca aggcagggct gtcgggtctc
     1441 ttctggcccg cgggtcgcaa ggacgccttc taccctccct tctgcatgtt ctggccaccg
     1501 cggacccccg gcgggctgcc cgtgcccacc tacctacagc ccccgccgca gcccccgtct
     1561 gcgctcggct gcgcgctggg tgatagcccg gccctgctgc gtcaggcctt cctggacctg
     1621 gccgagccgg gcggtgcagg tggcagcgcc gaggcagcgc cccctccggg ccaacctccc
     1681 cccgtggtgg ccaatggccc tggctccggt cctccagcta ctgggggcac tggagcacgc
     1741 gacacgctct tcgagtcgcc cccgggcggc agcggcgggg actgcagcgc cgggtccacg
     1801 ccacccgcag agcaaggagt gacgtccggg accgggtctg cgtcctccgg agcaggctct
     1861 gtgggcaccc gagtgccggc tccccatcac ccgcacctcc tggaagggcg caaggcgggc
     1921 ggcggcagct accaccattc cagcgccttc cgtccggtgg gcggcaagga cgacgcagaa
     1981 agcctggcca agctgcacgg ggcgtcggcg ggcacacccc actcagcccc agcgcatcac
     2041 catcaccacc accatcaccc gcaccatcac caccatcacc ctccgcagcc gccgtcgcca
     2101 ctgctgctgt tgcagcccca gcccgatgag ccggggtcgg agcgccacca cccagccccg
     2161 ccacccccgc caccgccgcc ccctctggcc ccgcagccgc accaccgagg ccttctgtcc
     2221 cccgagggca ccagctgcag ctaccccagt gaggacagct ctgaagacga ggaggacgag
     2281 gaggaagagc aggaggtgga cgtggagggc cacaagccac tcgaaggcga ggaagaggag
     2341 gacggtcgcg atcctgaaga tgaggaggaa gaagatgagg agacccgggt ccttctagga
     2401 gactccctgg ttggcggtgg ccggttcctc cagggccgag ggctatcgga gaaggggagc
     2461 ggtcgggacc gcacgacgcc cgccgtgggt gctttccctc tagcgctgaa ctcctccagg
     2521 ctgctacaag aggatgggaa actgggggac tctggaggct cggacctgcc ggcgcccccg
     2581 cccccacccc tggcccccca gaaagcaagc agcagtgggg gcagcaggcc aggcagccct
     2641 gtccaccatc catcactgga ggaggagccc tcgtacaaag ataatcagaa acctaaggaa
     2701 aacaaccaag ttattatatc tacaaaggat gacaacttct cagataagaa caagggacat
     2761 ggcttcttca tcacagattc tgattcttct ggagactttt ggagagaaag atcaggtgaa
     2821 catacacaag aaaccaattc acctcattcg ctcaaaaagg atgtagaaaa catgggaaaa
     2881 gaggaacttc agaaggtttt gtttgagcaa atagatttgc ggaggcggct ggagcaagaa
     2941 ttccaagtgt taaaaggaaa tacgtccttc ccagtcttca ataactttca ggatcagatg
     3001 aaaagggaac tggcttaccg agaagagatg gtgcaacagt tacaaatcat cccctatgca
     3061 gcaagcttga tcaggaaaga gaagcttggc gcccatctca gcaaaagcta aaaggcgaca
     3121 gacccactca ctcttgttct g
//
