LOCUS       NM_001347180            4012 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus selection and upkeep of intraepithelial T cells 4
            (Skint4), transcript variant 2, mRNA.
ACCESSION   NM_001347180 XM_006503165
VERSION     NM_001347180.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4012)
  AUTHORS   Bebee,T.W., Park,J.W., Sheridan,K.I., Warzecha,C.C., Cieply,B.W.,
            Rohacek,A.M., Xing,Y. and Carstens,R.P.
  TITLE     The splicing regulators Esrp1 and Esrp2 direct an epithelial
            splicing program essential for mammalian development
  JOURNAL   Elife 4, e08954 (2015)
   PUBMED   26371508
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4012)
  AUTHORS   Boyden,L.M., Lewis,J.M., Barbee,S.D., Bas,A., Girardi,M.,
            Hayday,A.C., Tigelaar,R.E. and Lifton,R.P.
  TITLE     Skint1, the prototype of a newly identified immunoglobulin
            superfamily gene cluster, positively selects epidermal gammadelta T
            cells
  JOURNAL   Nat Genet 40 (5), 656-662 (2008)
   PUBMED   18408721
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL831778.8.
            
            On Nov 17, 2016 this sequence version replaced XM_006503165.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR and
            coding sequence compared to variant 1. The resulting isoform (2) is
            shorter at the N-terminus compared to isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK162813.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-73                AL831778.8         76537-76609
            74-264              AL831778.8         77268-77458
            265-342             AL831778.8         91509-91586
            343-690             AL831778.8         122463-122810
            691-972             AL831778.8         124357-124638
            973-1080            AL831778.8         129084-129191
            1081-1134           AL831778.8         129668-129721
            1135-1242           AL831778.8         140492-140599
            1243-1365           AL831778.8         148228-148350
            1366-1491           AL831778.8         151013-151138
            1492-1617           AL831778.8         162507-162632
            1618-4012           AL831778.8         170203-172597
FEATURES             Location/Qualifiers
     source          1..4012
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 51.53 cM"
     gene            1..4012
                     /gene="Skint4"
                     /gene_synonym="9530098N22Rik"
                     /note="selection and upkeep of intraepithelial T cells 4"
                     /db_xref="GeneID:320640"
                     /db_xref="MGI:MGI:2444425"
     exon            1..73
                     /gene="Skint4"
                     /gene_synonym="9530098N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            74..264
                     /gene="Skint4"
                     /gene_synonym="9530098N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            265..342
                     /gene="Skint4"
                     /gene_synonym="9530098N22Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             270..1694
                     /gene="Skint4"
                     /gene_synonym="9530098N22Rik"
                     /note="isoform 2 precursor is encoded by transcript
                     variant 2; selection and upkeep of intraepithelial T-cells
                     protein 4; skint 4"
                     /codon_start=1
                     /product="selection and upkeep of intraepithelial T-cells
                     protein 4 isoform 2 precursor"
                     /protein_id="NP_001334109.1"
                     /db_xref="CCDS:CCDS84779.1"
                     /db_xref="GeneID:320640"
                     /db_xref="MGI:MGI:2444425"
                     /translation="MGATEVLTSYCVVLCLLQMVALSSGHFTVIGSQRPILATLGGNV
                     ELNCQLSPPQQAQHMEIRWFRNRYTQPVHLYRNGKNLHGETMSKYVERTELLTDAFNE
                     GKVILRILNVTVDDGGAYHCVFKDGEFYEEHITEVKVTATSSDIQILMHTPNIKGVML
                     ECHSGGWFPQPHMEWRNSKGEVIQATSKFHSQDKNKLFNMSMVLFIEASSHRNVICYF
                     QNLVTHQEQSINIVLSGELFSWKIVWIMILSTISFVMIDFCMTYCVQQQLIHEESLST
                     VDNDQCESDQSEGTCYKRNYPWIIIAVVPIISVFAIIGVMLFLHLEQRVTILEQHFEL
                     DTLWLEDISVILCVVIVSNINLIPLIYFRLHEHVPRFKDRSPILNKAVVFLHFIYFSI
                     VCGTILLVHLQLRNKVSISDSLFSLYNSWLTDISMILGFLLSIFIVTTIAKSSLFNKK
                     WCIGLCIHMKEAEATGGPCEGEEL"
     exon            343..690
                     /gene="Skint4"
                     /gene_synonym="9530098N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            691..972
                     /gene="Skint4"
                     /gene_synonym="9530098N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1080
                     /gene="Skint4"
                     /gene_synonym="9530098N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..1134
                     /gene="Skint4"
                     /gene_synonym="9530098N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1242
                     /gene="Skint4"
                     /gene_synonym="9530098N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1243..1365
                     /gene="Skint4"
                     /gene_synonym="9530098N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1491
                     /gene="Skint4"
                     /gene_synonym="9530098N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1492..1617
                     /gene="Skint4"
                     /gene_synonym="9530098N22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1618..4012
                     /gene="Skint4"
                     /gene_synonym="9530098N22Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actgatgtcc tacaaggcca tcctctgcta cttatgaggc tggagccatg gatccctcca
       61 tgtgtacact ttggaatgct gatttgagat tgacaagaaa aaacaccatc tcagtggata
      121 tcagttgaat ttctgaaaga gtatcgtttc tgatctagag gagttgttga tgactaatgt
      181 tgaagaagct tcgctaaaca acctgaaggc actgaaacat tttcaagaac cagaaaaaaa
      241 ttctctgtga agtctggagc tcaagtgtaa tgggagctac agaagtactt acttcatact
      301 gtgttgtctt atgcctcctc cagatggtag cactgagttc aggacacttt acagtgattg
      361 gctcacagag gcccatattg gctacattgg gtggaaatgt agaactcaat tgtcaattgt
      421 ccccaccaca acaagcacaa cacatggaga ttcgctggtt tcggaaccgt tatacacaac
      481 ctgtgcacct ataccgtaat ggtaaaaacc tacatggaga aactatgtct aagtatgtag
      541 aacggacaga actcctgact gatgccttta atgaggggaa agtgatcctc aggattctta
      601 atgtaactgt tgatgatggt ggtgcatacc actgtgtctt taaagatggt gaattctatg
      661 aagagcatat cacagaggtc aaggtcacag ccacaagctc agacatacag attctcatgc
      721 atacgcctaa tattaaaggt gtgatgttgg agtgtcattc aggcggttgg ttcccacagc
      781 ctcatatgga atggagaaat agcaaaggag aggtcattca agccacatca aaattccatt
      841 cacaggataa aaacaaattg ttcaacatgt caatggttct ttttattgaa gccagctctc
      901 acaggaatgt catttgctac tttcaaaacc ttgtaactca ccaagaacaa agcataaata
      961 ttgttctatc aggtgaactg ttttcatgga aaattgtttg gataatgatt ctgagcacaa
     1021 tatcatttgt gatgatagat ttctgcatga cttactgtgt tcagcaacag ctcatacatg
     1081 aagagtcact gtctaccgtg gacaatgatc agtgtgagtc tgatcaatct gagggtacct
     1141 gctacaagag aaattatcct tggattatta ttgcagtggt acccataatt tcagtgtttg
     1201 caatcatagg agtcatgctc tttttgcatc tagaacaaag agttacaatt ctagaacaac
     1261 attttgaatt ggacaccttg tggttggaag atattagtgt gatcctgtgt gtggtgatag
     1321 tgtccaacat caatctcata cctttgatat acttcagatt gcatgaacat gtacctagat
     1381 tcaaagaccg ttccccaata ttaaacaaag cagtggtatt cctgcatttc atttatttct
     1441 caatcgtatg tggaacaatc cttcttgtgc atctgcaatt acgtaacaaa gtttctattt
     1501 cagattcctt attttccttg tacaacagct ggctgacaga tatttcaatg attttaggat
     1561 ttctattgtc aattttcatt gttacaacca ttgcaaaatc atcattattt aataaaaagt
     1621 ggtgcattgg actgtgcatt cacatgaagg aagcagaagc aactggagga ccctgtgaag
     1681 gagaagaatt gtagcagcta gaagagttga agacatcagg aaaacatgcc acacaattaa
     1741 ccacacaggg ctagtggggg ctcacagaga cttaagggga aattataaag ccttaatgag
     1801 tctgcactgg gacctctgaa tatatgttgt ggttgttagg cttgttcttc ttgtgagagt
     1861 cttaacaatg ggtgtgcgta catgtttgtg catgtgcatg tatgcatgag tgtgtgtggg
     1921 gggggcattt ctgactattt tacctgcctt tggaatcatt ttacatcata cgaccttggt
     1981 atgagggtct gtgcctagta ttgttaaatg tatttcttta ggtgcttctt agccattagg
     2041 tattcctcag ttgagaatat tttgtttagc tctgtacccc atttttaata gggtcatttg
     2101 attttctgga gtacagcttc ttgagttctt tatatatatt agatattagc cctctatcag
     2161 atgtaggata gataaagatc ttttttcaat cttttggttg ccattttgtc ctattgcctt
     2221 acagaagctt tttaatttta tgagatccca tttgttgttt cttgatctca gagcataaac
     2281 caatggtgct ctgttcaggg aaattcctct gtgctcatgg gctctttccc acttactcct
     2341 ctattagttt tagtgtatct ggttttgagg tccttgatcc acttggacct gagcttttta
     2401 aaaggtgata agaatgggtt catttgcatt cttctacatg ctgacctcta gcaccatttg
     2461 ttgaaaatgc tgttcccctc ccccactgga tagctttagc acctatgtca aagatcaagt
     2521 gaccataggt gtgtaggtta atttctgggt cttcaatcct agtctattga tctacttgcc
     2581 tgtctctgta ccagtaccat gtagtctttt tatcactatt gctctgtaat acagcttgag
     2641 gtcagggatg gtgattacac cagaagtact tttattgttg agaatacttt atgctatcct
     2701 ggaagcaact aaagaaatgt tcaacatcct tagtcatcag agaaatgtaa atcaaaacaa
     2761 ccctgagatt tcagctcata ccagtcggaa tcactaagat caaaaactca ggtgacagca
     2821 gaagctagca aagatgtgga gaaagaagaa cattcctcca tttccagagt tgtctggaaa
     2881 tcagtctggt agttcctcag aaaactggac atagtattac ctaaggaccc agctggtata
     2941 ggagtggtat actcctggcc atatacccaa aagattctcc aacatataac actatgttca
     3001 tagcagcctt atttgtaata gccagaagct ggaaagaacc cagatgtact tcaacagagg
     3061 catagataca gaaaaggtgc tatatctaca caatggagta ctatcagcta ttaaaaacaa
     3121 tgagtttatg aaattcttag gcaaatggat ggaacaagaa aatatcatcc tgaaagaggt
     3181 aacccaatca taaaaaacaa acaaacacag caaaaaacca aaccaaacta aaaacaaaaa
     3241 caaaaacgaa tatggtattc actcattggt aagtggatat tagccccaaa gcttggaata
     3301 cctaatatac aattcacaga acagaagaag ctaaaaaacg aaggaagacc aaaatgtggg
     3361 tgctttgttc cttctgaaaa ggggaataaa atactcacag gagcaaatac agaaacaaac
     3421 tatgaagcag agactgaagg gaaggccatt caaaggttgc tccacctggg aatccatcct
     3481 atatatagcc aacaaatcca gacactattg tggattccaa gaagttcaag ctgacaggaa
     3541 cctgatatag ctgtctcctg agaggctctg ccagaacatg acaaatacag aggctgatgt
     3601 ttggactgag catgcgctcc ccagtggagg aattagagaa aggactgaag gacatgaagg
     3661 gatttgtaac tccatagaaa gaacaataat atcaacctac cagacccccc cccccccagc
     3721 tcctagggac taaaccatca accaaggagc acacatggag ggacccatgc cttgagctgc
     3781 atatgtagca gagctttgtc cagcatcaat ggtaggagaa atcctttgtc ctttgaaggc
     3841 tcaatgcctt agtgtaggga aattcaaggg tggagagaag agcatgggtg ggtaggtggg
     3901 ggaacataga agcaggggac aggtgatggg ttaggggatt ttgtgggtag agaactggga
     3961 aaattgataa tatttgaaat gtaaataaag aaaatatcca ataataaaat tt
//
