LOCUS       NM_001102474            3843 bp    mRNA    linear   ROD 04-APR-2024
DEFINITION  Mus musculus selection and upkeep of intraepithelial T cells 3
            (Skint3), transcript variant 1, mRNA.
ACCESSION   NM_001102474
VERSION     NM_001102474.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3843)
  AUTHORS   Boyden,L.M., Lewis,J.M., Barbee,S.D., Bas,A., Girardi,M.,
            Hayday,A.C., Tigelaar,R.E. and Lifton,R.P.
  TITLE     Skint1, the prototype of a newly identified immunoglobulin
            superfamily gene cluster, positively selects epidermal gammadelta T
            cells
  JOURNAL   Nat Genet 40 (5), 656-662 (2008)
   PUBMED   18408721
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK040383.1, EF494894.1 and AL611968.7.
            
            On Jan 27, 2017 this sequence version replaced NM_001102474.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EF494894.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849375,
                                           SAMN00849376 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-176               AK040383.1         2-177
            177-1620            EF494894.1         1-1444
            1621-3843           AL611968.7         91272-93494
FEATURES             Location/Qualifiers
     source          1..3843
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 51.53 cM"
     gene            1..3843
                     /gene="Skint3"
                     /gene_synonym="A430090E18Rik; Skint-3"
                     /note="selection and upkeep of intraepithelial T cells 3"
                     /db_xref="GeneID:195564"
                     /db_xref="MGI:MGI:3045331"
     exon            1..200
                     /gene="Skint3"
                     /gene_synonym="A430090E18Rik; Skint-3"
                     /inference="alignment:Splign:2.1.0"
     exon            201..281
                     /gene="Skint3"
                     /gene_synonym="A430090E18Rik; Skint-3"
                     /inference="alignment:Splign:2.1.0"
     CDS             206..1582
                     /gene="Skint3"
                     /gene_synonym="A430090E18Rik; Skint-3"
                     /note="isoform a precursor is encoded by transcript
                     variant 1; Selection and upkeep of intraepithelial T-cells
                     protein 3"
                     /codon_start=1
                     /product="selection and upkeep of intraepithelial T-cells
                     protein 3 isoform a precursor"
                     /protein_id="NP_001095944.1"
                     /db_xref="CCDS:CCDS51268.1"
                     /db_xref="GeneID:195564"
                     /db_xref="MGI:MGI:3045331"
                     /translation="MGSIQIIFAAYCVVLCVLQMLVLSSEQFTITGLERPVLAPLGGI
                     LELSCQLSPPQNAQQMEIRWFRNRYTEPVYLYRNGKDLHGETISKYVERTELLKHDIG
                     KGKVTLRVFKVTVDDDGSYHCVFKDGIFYEEHITEVKVTATSSDIKIIMHPPNIKGVM
                     LECHSRGWFPQPHMEWRDSNGQVIPATSKSQSQDENKLFNMTMNLFADVGLHQIVTCY
                     IQNLLTHQEESISIVLTGDLFSWKIDWILILSIIACVMIPYSMTSYLQQHLIHGSCSQ
                     RSHHWRKNAMVCMSSVIAIIGSMLILHLKQRVPISDQHFELDTLYLEDISVILCVVIV
                     FNLKLNLLTYYRLERKYDGCTPGCKACFYILKIIIIILPFVFTFGCYNAIFLKYHQLQ
                     KKVSIPDPLYYFYTSWLVNMEMLGVFLVFFPTFINLIEFSQFIKTVPKPIWLCQENMR
                     EDDAIRHR"
     exon            282..629
                     /gene="Skint3"
                     /gene_synonym="A430090E18Rik; Skint-3"
                     /inference="alignment:Splign:2.1.0"
     exon            630..911
                     /gene="Skint3"
                     /gene_synonym="A430090E18Rik; Skint-3"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1019
                     /gene="Skint3"
                     /gene_synonym="A430090E18Rik; Skint-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..1127
                     /gene="Skint3"
                     /gene_synonym="A430090E18Rik; Skint-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1262
                     /gene="Skint3"
                     /gene_synonym="A430090E18Rik; Skint-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1263..1388
                     /gene="Skint3"
                     /gene_synonym="A430090E18Rik; Skint-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1389..1513
                     /gene="Skint3"
                     /gene_synonym="A430090E18Rik; Skint-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1514..3843
                     /gene="Skint3"
                     /gene_synonym="A430090E18Rik; Skint-3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atatcaggct tgcagaatca taggggcaga ctttcagagt aggagagtgg acattaatat
       61 ttaattttcc tgatttccat ataactctga tatactttat ggcttcaaga aaactgtgga
      121 agtattatca gaaactcaag tgacctaact gatacattca cagacgcgat agagagctga
      181 cttaggatca tccatctcag gtgtgatggg atctatacaa ataatttttg ctgcatactg
      241 tgttgtcttg tgcgtcctcc agatgttagt actgagttca gagcagttca caattactgg
      301 cttagagagg ccagtccttg ccccattagg tggaatcctt gaactcagtt gtcagttgtc
      361 cccaccacaa aatgcacaac aaatggagat tcgctggttc cggaatcgct atacagaacc
      421 tgtgtacctg tacaggaatg gtaaagacct gcatggagaa actatctcca agtatgtgga
      481 gcggacagaa ctcctaaaac atgacattgg aaaagggaaa gtgaccctca gggtctttaa
      541 agtgacagtt gatgatgatg gatcatacca ttgtgtcttc aaagatggta tattctatga
      601 agagcatatc acagaggtca aggtcactgc cacaagctca gatataaaga ttataatgca
      661 tcccccgaat attaaaggtg tgatgcttga gtgtcattca agaggttggt tccctcagcc
      721 tcatatggaa tggagagata gcaatggaca ggtcattcca gctacatcaa aatcccagtc
      781 acaggatgaa aacaaattgt tcaacatgac aatgaacctt tttgctgatg ttggcctaca
      841 ccagattgtc acttgctaca ttcaaaacct tttaactcat caagaagaaa gcataagtat
      901 tgtcctaaca ggtgatcttt tttcatggaa aattgattgg atattgattt tgagtataat
      961 agcatgtgtg atgataccct actccatgac ttcctatctt caacaacatc tcatacatgg
     1021 tagctgctct cagagatcac atcattggag aaagaatgca atggtatgca tgagttcagt
     1081 gattgcaatt ataggatcca tgcttatttt gcatctaaaa caaagagtcc caatttcaga
     1141 tcaacatttt gaattggata ctttatactt ggaagatatt agtgtgatcc tgtgtgtggt
     1201 gattgtgttt aacctcaagc tcaatttact tacttactac agattggaac gtaaatatga
     1261 tggatgtaca cctggatgca aagcatgctt ctatatatta aaaataataa taataatatt
     1321 gccattcgtg tttacctttg ggtgctataa tgcaatcttt ttaaaatatc atcaattaca
     1381 gaaaaaagtt tctattccag atcccttata ttacttctac actagctggc ttgtgaatat
     1441 ggaaatgctg ggagtatttc tggtcttctt tcctactttt ataaacttaa tagaattttc
     1501 gcaattcata aaaactgttc caaagcccat atggttatgc caagagaata tgagagaaga
     1561 tgatgcaata agacacagat aaacattaat ttgaactgga gaatcctgca aaagatggag
     1621 cagaagaatt gtagtagcca gaggagtgga ggacaccatg agaacatggg tcacagaatc
     1681 aactaagcag ggctcatagg ggattataaa gactgaagtg aaaattacaa gcctatacgg
     1741 gtctatggtt ggttttcagc atatatgtat tgtttattta acttgttttt ttttttttaa
     1801 tgggactcct aaccctaaaa gtgcacttat gtgaggaaat ggggactctt ttgcctgctc
     1861 ttgaaatcct ttttctccca ttgtattgct tttgccaact tcagtaggag ggtttgtgcc
     1921 cagtgttatt gtaacttatt atgcttggtg tgtttggtag atatccctgg gaggcctgtt
     1981 tgtttctgaa gagttagttg cagaggagag ataaatgggt tagattggga gtagtagagt
     2041 aaggggaaac tggtcaggag tattgtatga gagaagaatg aatgtaaaaa tcttacattg
     2101 tgcttacact aaatatgtga ggacattatt ttcttgtcaa tataaaaatt aataactgaa
     2161 acaagaaaga gggtagagaa taaaaatcta tagaatacta agcagagaac ataaagcatg
     2221 ctacctccac taaaggatca cagattattt agaaagagga gagaaatgag tacaaaagcc
     2281 agaaacaaga gataattaca aggaaataat actttttgga tacacaaggg tagctacaca
     2341 tatgaactca caatggtttg tacaccatga ataagacttg tccaactcta agtcagatga
     2401 aatcttggca atcagagaag agtttagcat gagttctcat ccctggcata aaagttattg
     2461 actggtgtta ggtgtttgga aaggaaggtt agtttttttg ttgttgtttt gattttttaa
     2521 tataatagct gccaataagt tgctcatgct ggagtggatg gccacacaac aaacatattt
     2581 tggaagcaca aattgtcctg aatgaaaagc caaaagacac aaatttaggt ggttaaggat
     2641 aaagagatgg atctgtaaag agttggggat aaataataaa agatatgcaa aattctcaaa
     2701 aaatgaataa aaaacatttt aaaaactgat aaaaaatccc taaataatat catgaccttc
     2761 aaagaaggaa agtatattgc ttggatgtat tgtatgagat aataagtaaa aataaaaata
     2821 gaaaaagtat cataaaacac ttgtttagca cttcagtttt agtaggtagt aaaaatactc
     2881 cgatatgatt tgacttatga aatatatatg agaatgatta tttgatataa ataaattctg
     2941 tatcatttta tatatagtat ttgaatactg agcatccttt tgtactcata gataagccaa
     3001 gggataccca tcttgggcag tttaattgta ctccctttca aaataatttc cctactcaca
     3061 tttgtttact gcttattcca ccttctggag ggatgaagag ggtcacaaaa ggctgctcac
     3121 cacgtgttgt agaaactcct ccttgattgc acagggctag aatatataga ccaaagagaa
     3181 gactctacct atgtgactaa gaaaaagtcc tcatttcttc ttggtaaagg ctctccaagt
     3241 atagcctgct tcagttataa gggagcaact acatccccac aagcaaatcc taacctagac
     3301 tgtcttagga agtcaaataa atttatttgt tgctcaggat aattttggga ccttaacaga
     3361 gttggtagat gttgtttaaa atgtctctct atgtgaagga attatagcaa tactgtctgg
     3421 gaatcaatat tccatggaca tcaagacata taattcccca gatctatatt catgtcagag
     3481 tcaataatca tcaatatctg gaactataaa aaaacagaga ttgtgtttaa tggatataag
     3541 ataactaatc tacctattgt actgatgaga gaaattgaaa tacaatgatt ttctgtactt
     3601 tatggctaat attcactgat aagtgagtaa ataccatgta ttctttttgg gtctgcttac
     3661 cttactcaag atgatatttt gtaattccat ccatttgcct gaaaaattaa tgatgttctt
     3721 gtttttaata gctgagtagt attctattat ataaacctac attttatata tcaattttcc
     3781 ttaagttgag aggcatctga gttgtttcct gtctcgggtt attacaaata aagctctatg
     3841 aac
//
