LOCUS       NM_001285963            1258 bp    mRNA    linear   ROD 08-NOV-2023
DEFINITION  Mus musculus selection and upkeep of intraepithelial T cells 2
            (Skint2), transcript variant 1, mRNA.
ACCESSION   NM_001285963
VERSION     NM_001285963.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1258)
  AUTHORS   Jandke A, Melandri D, Monin L, Ushakov DS, Laing AG, Vantourout P,
            East P, Nitta T, Narita T, Takayanagi H, Feederle R and Hayday A.
  TITLE     Butyrophilin-like proteins display combinatorial diversity in
            selecting and maintaining signature intraepithelial gammadelta T
            cell compartments
  JOURNAL   Nat Commun 11 (1), 3769 (2020)
   PUBMED   32724083
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1258)
  AUTHORS   Barbee SD, Woodward MJ, Turchinovich G, Mention JJ, Lewis JM,
            Boyden LM, Lifton RP, Tigelaar R and Hayday AC.
  TITLE     Skint-1 is a highly specific, unique selecting component for
            epidermal T cells
  JOURNAL   Proc Natl Acad Sci U S A 108 (8), 3330-3335 (2011)
   PUBMED   21300860
REFERENCE   3  (bases 1 to 1258)
  AUTHORS   Boyden LM, Lewis JM, Barbee SD, Bas A, Girardi M, Hayday AC,
            Tigelaar RE and Lifton RP.
  TITLE     Skint1, the prototype of a newly identified immunoglobulin
            superfamily gene cluster, positively selects epidermal gammadelta T
            cells
  JOURNAL   Nat Genet 40 (5), 656-662 (2008)
   PUBMED   18408721
REFERENCE   4  (bases 1 to 1258)
  AUTHORS   Yang Y, Liu XK, Nguyen T, Bishop C, Graf D and Dong C.
  TITLE     Characterization of B7S3 as a novel negative regulator of T cells
  JOURNAL   J Immunol 178 (6), 3661-3667 (2007)
   PUBMED   17339463
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            EU099299.1.
            
            [WARNING] On Nov 28, 2023 this sequence was replaced by
            NM_001285963.2.
            
            Transcript Variant: This variant (1) represents the shorter
            transcript but encodes the longer isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: EU099299.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1258              EU099299.1         1-1258
FEATURES             Location/Qualifiers
     source          1..1258
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 51.53 cM"
     gene            1..1258
                     /gene="Skint2"
                     /gene_synonym="A430070M19; B7S3; Skint-2"
                     /note="selection and upkeep of intraepithelial T cells 2"
                     /db_xref="GeneID:329919"
                     /db_xref="MGI:MGI:3649629"
     exon            1..26
                     /gene="Skint2"
                     /gene_synonym="A430070M19; B7S3; Skint-2"
                     /inference="alignment:Splign:2.1.0"
     exon            27..98
                     /gene="Skint2"
                     /gene_synonym="A430070M19; B7S3; Skint-2"
                     /inference="alignment:Splign:2.1.0"
     exon            99..446
                     /gene="Skint2"
                     /gene_synonym="A430070M19; B7S3; Skint-2"
                     /inference="alignment:Splign:2.1.0"
     exon            447..728
                     /gene="Skint2"
                     /gene_synonym="A430070M19; B7S3; Skint-2"
                     /inference="alignment:Splign:2.1.0"
     exon            729..836
                     /gene="Skint2"
                     /gene_synonym="A430070M19; B7S3; Skint-2"
                     /inference="alignment:Splign:2.1.0"
     exon            837..944
                     /gene="Skint2"
                     /gene_synonym="A430070M19; B7S3; Skint-2"
                     /inference="alignment:Splign:2.1.0"
     exon            945..1067
                     /gene="Skint2"
                     /gene_synonym="A430070M19; B7S3; Skint-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1068..1258
                     /gene="Skint2"
                     /gene_synonym="A430070M19; B7S3; Skint-2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aactgttgtg gtatcatctg gcttaggtgt aatgggagct acaggagtac ttctctgtgt
       61 tgtcttacac ttcctccaga tggtaacaca gagttcagaa aaattcacag tgactggctt
      121 acagaggcca gtcttggcac cattgggtgg aaatgttgaa ctgagttgtc agttgtctcc
      181 gccacaacaa gcacagcata tggagattcg ttggtttcga aatcgctata gagagcctgt
      241 gtacctgtac aggaatggta aagacctgca tggagaaact atctccaagt atgtggagcg
      301 gactgaactc ctgaaagatg acattggaaa ggggaaggtg accctcagga tctttaaact
      361 gacagctgat gatgatgggt cataccactg tgtcttcaaa gttggagagt tctatgaaga
      421 gcatatcaca gaaatcaagg tcacagccac aagctcagtc atgtacattc taatgcagcc
      481 ccctaatatc aaaggtgtga tgttggagtg tcattcagga ggttggttcc cacagcctca
      541 tatggaatgg agagacaaca agggaaatat cattccagct acatcaaagg cccattcaca
      601 ggatgaaaac aaattgttca acatgacaat gacccttctt attgaagcca gctcccacag
      661 gagtatcact tgctatcttc aaaaccttct aactcaccaa gaagaaagca taagtattgt
      721 cctatcaggt gaactatttt catggaaacg tgtttggata atgattctga ctacaatagg
      781 attcatgatg atagccttct gcatgactta ttgtgttcag caacatctct tatatggtac
      841 cttctctaag gggaaatgtc attggttaaa gagtacaatg atattcatgt tttcagtgat
      901 tgcagttaca ggagtcatgc tcattttgca tctaaaacaa agagtcccag tttcagatca
      961 acattttgaa ttggacactt tgtggcttga agatattagt gtgatcctgt gtgtgctgat
     1021 cgtgtttatc atcaagctca tttcatttat ttacttcaga ttagaaggag atcatcaggg
     1081 gtggagtctg ccaccctatc tttctgccac tcccactgct gctatctgcc gcctagctgt
     1141 tccagagtat tcacgtggtc acctgcagct ggactccgaa gatgatttgg ccggaatggg
     1201 cccctccccc ttcttcataa ccccgtgttt ctgaatagta aaattgagct ttgatcag
//
