LOCUS       NM_177668               1729 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus selection and upkeep of intraepithelial T cells 10
            (Skint10), mRNA.
ACCESSION   NM_177668 XM_149480
VERSION     NM_177668.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1729)
  AUTHORS   Boyden,L.M., Lewis,J.M., Barbee,S.D., Bas,A., Girardi,M.,
            Hayday,A.C., Tigelaar,R.E. and Lifton,R.P.
  TITLE     Skint1, the prototype of a newly identified immunoglobulin
            superfamily gene cluster, positively selects epidermal gammadelta T
            cells
  JOURNAL   Nat Genet 40 (5), 656-662 (2008)
   PUBMED   18408721
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK040044.1, AK037152.1 and BB749775.1.
            
            On Feb 24, 2007 this sequence version replaced NM_177668.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK037152.1, EF494905.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                AK040044.1         7-42
            37-1412             AK037152.1         2-1377
            1413-1729           BB749775.1         124-440
FEATURES             Location/Qualifiers
     source          1..1729
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 51.53 cM"
     gene            1..1729
                     /gene="Skint10"
                     /gene_synonym="A030001H23Rik; Gm570"
                     /note="selection and upkeep of intraepithelial T cells 10"
                     /db_xref="GeneID:230613"
                     /db_xref="MGI:MGI:2685416"
     exon            1..107
                     /gene="Skint10"
                     /gene_synonym="A030001H23Rik; Gm570"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..1105
                     /gene="Skint10"
                     /gene_synonym="A030001H23Rik; Gm570"
                     /note="selection and upkeep of intraepithelial T-cells
                     protein 10; skint 10"
                     /codon_start=1
                     /product="selection and upkeep of intraepithelial T-cells
                     protein 10 precursor"
                     /protein_id="NP_808336.1"
                     /db_xref="CCDS:CCDS38841.1"
                     /db_xref="GeneID:230613"
                     /db_xref="MGI:MGI:2685416"
                     /translation="MFLRTQMEQSQADIFALIKPHFGVMESSASYLPGFFMTFLLLQT
                     TVLTQAMSLDIQINIQVPDTEGVLLECTSGSLIPPAEMTWRDSKGNIIPHSTTFDSQD
                     RAGLLYLKSSILLKNRVQSPITCSIYNVTTNREKKRSVVLPDILFKSEYMSLMSNKFS
                     CPLTYLFIIIFLNCLKGMLDFCCLKGKPVYFRELINKIKEVLNIKMRACCTLIWEFLL
                     IVLYIAFLPFYLKFRSRASILDDAYPLHSNWLWDICIVLSVLMIFFTGLSLFLLWTLN
                     CYGQMSYLPSMSMDLSKHDFEQNSSKSSEFQENYDVSCEIFLGTFEETIFSQHQESCI
                     EDSFNPLQPLRLDCSLNWKT"
     exon            108..188
                     /gene="Skint10"
                     /gene_synonym="A030001H23Rik; Gm570"
                     /inference="alignment:Splign:2.1.0"
     exon            189..470
                     /gene="Skint10"
                     /gene_synonym="A030001H23Rik; Gm570"
                     /inference="alignment:Splign:2.1.0"
     exon            471..641
                     /gene="Skint10"
                     /gene_synonym="A030001H23Rik; Gm570"
                     /inference="alignment:Splign:2.1.0"
     exon            642..746
                     /gene="Skint10"
                     /gene_synonym="A030001H23Rik; Gm570"
                     /inference="alignment:Splign:2.1.0"
     exon            747..869
                     /gene="Skint10"
                     /gene_synonym="A030001H23Rik; Gm570"
                     /inference="alignment:Splign:2.1.0"
     exon            870..1729
                     /gene="Skint10"
                     /gene_synonym="A030001H23Rik; Gm570"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1394..1399
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Skint10"
                     /gene_synonym="A030001H23Rik; Gm570"
                     /note="hexamer: TATAAA"
     polyA_site      1415
                     /gene="Skint10"
                     /gene_synonym="A030001H23Rik; Gm570"
                     /note="major polyA site"
ORIGIN      
        1 tttcctttct ttgcacacag caactttggc ttacacagta atgtttctga ggacacagat
       61 ggagcaaagt caagctgaca tttttgcatt gattaaacca cattttggtg tgatggagtc
      121 ttcagcttcc tatttacctg gattctttat gaccttcctt ctcttacaga ccacagtact
      181 cacccaagct atgagcttgg atatacagat taacattcag gttccagata cagaaggggt
      241 actcttggag tgtacttcag gaagcttgat cccacctgct gagatgacat ggagagacag
      301 caaagggaat ataattccac attcaaccac atttgactct caggatagag ctgggttatt
      361 gtatttgaaa agcagcattc ttctgaagaa cagagttcaa agtcctatta cttgctccat
      421 ttacaatgta acaactaatc gggagaaaaa aagaagcgtt gtcctaccag atatcctatt
      481 caaatcggaa tatatgtcat tgatgtcaaa caaattttca tgtcctttaa catatttatt
      541 cattataatt tttcttaatt gtctcaaagg aatgcttgat ttctgttgtc tcaaaggaaa
      601 acctgtttat ttcagagaac taatcaataa aatcaaggaa gttttgaata ttaaaatgag
      661 agcttgctgt acacttatct gggagtttct actgatagtt ttgtatattg cgttcctccc
      721 tttctacttg aaattcagaa gcagagcttc tattttggat gatgcatacc cattacatag
      781 taattggctg tgggacatat gcatagtctt gagtgtgctg atgatatttt tcactgggct
      841 cagtttgttt ctactttgga ccctaaactg ttatggtcag atgtcatact taccttccat
      901 gagcatggat ctttccaaac atgactttga gcaaaatagt tctaaatctt ctgagttcca
      961 agaaaattat gatgtgagct gcgaaatatt cctaggaact tttgaagaaa caatatttag
     1021 tcaacaccaa gaaagttgta tagaggatag cttcaaccca cttcagccct taagattgga
     1081 ttgcagtctt aattggaaaa cttgaggcac taaagaaaga cagaaatgga tgtcttgaac
     1141 tataaaattt atatctatga aacatacaat caaggggatc ttctgattac attttgttat
     1201 gcttcaaaag gataattttt aaaaaataca ttttagtatg ttagaattac attatattcc
     1261 acttcttctc tttcatctct ctatcttctc ccaggtactt tcctttcgat gctttccatg
     1321 tacccctgct caaactgata ctctattgat tattattgtt aaacatgcac atctgtatat
     1381 gtatgcaaag atatataaat acaaccttct gcacatattt tgttgtttgt gtctatataa
     1441 tttcagggca aaaattagag attttgatgc taggaagtat ccacatggcc tgtgattaat
     1501 atccccctcc atatattaaa ttgaataagg atttaatcaa tgtaattttt tttaaatgat
     1561 gtcttgacaa cttttcttca agtgtgaaga taggtttttc ttattttaag aaaggatgat
     1621 tgaaagcaat aaaaacatca agacaaaact ttaagggaaa gttttgaaaa tgaaatattt
     1681 ttgtataaaa tcagtgttta tcagcaaaat aaaatatctt gttagctac
//
