LOCUS       NM_028317               4884 bp    mRNA    linear   ROD 13-FEB-2025
DEFINITION  Mus musculus SKI/DACH domain containing 1 (Skida1), mRNA.
ACCESSION   NM_028317 XM_140828
VERSION     NM_028317.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4884)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4884)
  AUTHORS   Youlten,S.E., Kemp,J.P., Logan,J.G., Ghirardello,E.J., Sergio,C.M.,
            Dack,M.R.G., Guilfoyle,S.E., Leitch,V.D., Butterfield,N.C.,
            Komla-Ebri,D., Chai,R.C., Corr,A.P., Smith,J.T., Mohanty,S.T.,
            Morris,J.A., McDonald,M.M., Quinn,J.M.W., McGlade,A.R.,
            Bartonicek,N., Jansson,M., Hatzikotoulas,K., Irving,M.D.,
            Beleza-Meireles,A., Rivadeneira,F., Duncan,E., Richards,J.B.,
            Adams,D.J., Lelliott,C.J., Brink,R., Phan,T.G., Eisman,J.A.,
            Evans,D.M., Zeggini,E., Baldock,P.A., Bassett,J.H.D., Williams,G.R.
            and Croucher,P.I.
  TITLE     Osteocyte transcriptome mapping identifies a molecular landscape
            controlling skeletal homeostasis and susceptibility to skeletal
            disease
  JOURNAL   Nat Commun 12 (1), 2444 (2021)
   PUBMED   33953184
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4884)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4884)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   5  (bases 1 to 4884)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928589.11.
            
            On Jan 27, 2022 this sequence version replaced NM_028317.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BQ771333.1, CF739107.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-130               AL928589.11        173961-174090       c
            131-4884            AL928589.11        168973-173726       c
FEATURES             Location/Qualifiers
     source          1..4884
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 12.83 cM"
     gene            1..4884
                     /gene="Skida1"
                     /gene_synonym="2810030E01Rik; 5730507N06Rik; DLN-1"
                     /note="SKI/DACH domain containing 1"
                     /db_xref="GeneID:72668"
                     /db_xref="MGI:MGI:1919918"
     exon            1..130
                     /gene="Skida1"
                     /gene_synonym="2810030E01Rik; 5730507N06Rik; DLN-1"
                     /inference="alignment:Splign:2.1.0"
     exon            131..4884
                     /gene="Skida1"
                     /gene_synonym="2810030E01Rik; 5730507N06Rik; DLN-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             244..2973
                     /gene="Skida1"
                     /gene_synonym="2810030E01Rik; 5730507N06Rik; DLN-1"
                     /note="protein DLN-1"
                     /codon_start=1
                     /product="SKI/DACH domain-containing protein 1"
                     /protein_id="NP_082593.2"
                     /db_xref="CCDS:CCDS57154.1"
                     /db_xref="GeneID:72668"
                     /db_xref="MGI:MGI:1919918"
                     /translation="MGDLKSGFEEVDGVRLGYLIIKGKQMFALSQVFTDLLKNIPRTT
                     VHKRMDHLKVKKHHCDLEELRKLKAINSIAFHAAKCTLISREDVEALYTSCKTERVLK
                     TKRRRVGRALATKAPPPERAAAASPRPAFWKDKHQLWRGLSGAARPLPISAQSQRPGA
                     AAARPAAHLPQIFSKYPGSHYPEIVRSPCKSSLNYETAQLQGNYVAFHSDPAYFRSLL
                     CSKHPAAAAAAAAAAAAAAAAAAYYQTAGPQPKAATGAGGPVSLTYRCKRKRGGAKNC
                     LLPPHAGARRLLLLPRSYKAKAAAAAAAAAAAAAAAAGATCLERFHLVNSFCPPPHHH
                     HHHHHHHHHHHHRAQQPTPSHHPSHHHRPQPHLGSFPESCSSDSESSSYSDHAANDSD
                     FGSSLSSSSNSVSSEEEEEEGEEEEEEEEEEEGGSGASDSSEISSEEEDSSTESDSSS
                     GSSQVSVQSIRFRRTSFCKPPSVQAQANFLYHLASAAAATKPAAFEDAGRLPDLKSSV
                     KAESPEEWSLQSWAPKGTPVYCPASLGSCFPEIRNDRVSEITFPHSEISSTVKRTDLT
                     INCHAEGASSPSPKTNNVFPQQRILREARKCLQATPTTHCAENSTIAARFLNNDSCGT
                     TANSGKDSKIPHCPEFATDLPSLQSDPRVDTATAAAAAAAATKAESLCTGTGDKTLPF
                     LHNIKIKVEDSSANEEYEPELITNKLKWECNDAEGEFYNMTEKKEEDALVPTAKEGFA
                     CPEKETPSLNPLAQSQGLSCTLGSPKPEDGEYKFGARVRKNYRTLVLGKRPVLQTPPV
                     KPNLKSARSPRPTGKTETHEGTLDDFTVLNRRKKVASNVASAVKRPFNFMANFPCPPS
                     LIIGKDGDLWPAYSLNTTKDSQPPHKAHPIWKWQLGGSAIPLPPSHKFRKFNS"
     regulatory      4226..4231
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Skida1"
                     /gene_synonym="2810030E01Rik; 5730507N06Rik; DLN-1"
                     /note="hexamer: ATTAAA"
     polyA_site      4245
                     /gene="Skida1"
                     /gene_synonym="2810030E01Rik; 5730507N06Rik; DLN-1"
                     /note="major polyA site"
     regulatory      4476..4481
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Skida1"
                     /gene_synonym="2810030E01Rik; 5730507N06Rik; DLN-1"
                     /note="hexamer: ATTAAA"
     polyA_site      4496
                     /gene="Skida1"
                     /gene_synonym="2810030E01Rik; 5730507N06Rik; DLN-1"
                     /note="major polyA site"
     regulatory      4507..4512
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Skida1"
                     /gene_synonym="2810030E01Rik; 5730507N06Rik; DLN-1"
                     /note="hexamer: CATAAA"
     polyA_site      4528
                     /gene="Skida1"
                     /gene_synonym="2810030E01Rik; 5730507N06Rik; DLN-1"
     regulatory      4860..4865
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Skida1"
                     /gene_synonym="2810030E01Rik; 5730507N06Rik; DLN-1"
                     /note="hexamer: AATACA"
     polyA_site      4884
                     /gene="Skida1"
                     /gene_synonym="2810030E01Rik; 5730507N06Rik; DLN-1"
ORIGIN      
        1 acttcactct gtcattttat ttgtagctaa agcagcggcg ggaatagcag ctgcatttct
       61 tttctctttc tcccttcaca ttccattatc atagtgctcc aatggagaag gaaggagtag
      121 cggggcccag caggatgcct tgagacacac gcagcatctg gcggaggatt aacatacata
      181 catgtgtatg tatgcgtcac gtatatattt actgcaaatg gtggggatca tttagtgccc
      241 gagatgggag acctgaagtc aggtttcgaa gaggtggatg gcgtgaggct cggctacctc
      301 atcattaaag ggaagcaaat gtttgctctc tcccaagtct tcacagatct gctgaaaaac
      361 atcccgagga cgaccgtgca caagcgcatg gatcatctga aagtgaaaaa gcaccactgc
      421 gatctggagg agttgcggaa actcaaagca atcaacagta tcgccttcca cgcggccaaa
      481 tgcacgctca tctcccggga agacgtagaa gcgctctaca catcctgcaa aaccgagcgt
      541 gtgctcaaga ccaagcgaag gagagtcggt cgggccctgg ccacaaaggc gccgccgcca
      601 gagcgcgccg ccgccgccag cccccgcccg gctttttgga aggacaagca ccaactttgg
      661 cggggcctga gcggagccgc gcggcccctg ccaatcagcg cgcagtccca gcgtccgggc
      721 gccgccgccg cgcgccccgc cgcccatcta cctcagattt ttagcaaata cccgggctcc
      781 cactacccgg agatcgttcg ctcgccttgc aaatcctctt taaactatga aactgcccag
      841 ctccagggaa actacgtcgc cttccactcg gaccccgctt attttcggag cctgctgtgc
      901 agcaagcacc cggctgcagc cgccgccgcc gccgccgccg ctgctgctgc cgccgccgcc
      961 gccgcctact accagactgc cgggcctcag cccaaggcgg cgaccggcgc gggaggccca
     1021 gtgagcctga cttaccgctg caagcgcaag cgcgggggcg ccaagaactg cctgctcccg
     1081 cctcacgccg gagcccggcg cctgctgctg ctgcccagat cctacaaagc caaggcggcg
     1141 gcggcggcag cagcggcggc tgctgctgcg gcggcggcgg ccggggccac ttgcttggag
     1201 aggtttcatc tggtcaacag cttctgcccg cctccccacc accaccatca ccatcaccac
     1261 catcatcatc accatcacca ccgagcccag cagccaacgc cgagtcacca cccctctcat
     1321 caccaccggc cgcaacccca tctaggaagc tttcccgaga gttgtagcag cgactccgag
     1381 tccagctcct actccgacca tgcagccaat gactcggatt ttggctccag tttgtccagc
     1441 tccagcaact cggtgtcctc agaggaagag gaggaggaag gagaggagga ggaggaagag
     1501 gaggaggagg aagagggggg cagcggggcc tcggattcca gtgaaatcag ctcggaggag
     1561 gaggattctt ccaccgagtc agactccagc tccgggtcca gccaagtgtc agtgcagagc
     1621 atccgtttca ggcgcaccag cttctgcaag cctcccagcg tgcaggcgca ggccaacttc
     1681 ttgtaccatc tggcctccgc cgccgctgca accaaacccg ctgctttcga ggatgccggc
     1741 cgacttcccg acctcaagag tagtgtcaaa gccgagtcac cagaggagtg gagtctgcag
     1801 agctgggctc ccaaagggac tccggtgtac tgcccggcca gcttggggag ttgtttccca
     1861 gagataagaa acgatagggt atctgagatt acattcccac actctgaaat atccagtact
     1921 gtaaagagaa ctgacctgac aattaactgc catgcagagg gggcctcttc acctagccca
     1981 aagacaaaca atgtatttcc acaacaaaga atactccgag aggctaggaa atgcctacaa
     2041 gcaactccta ctacacactg tgcagaaaac agcacaatag ctgctaggtt cttaaataat
     2101 gattcgtgtg gaacaacagc aaattcagga aaagattcca aaatccctca ttgtcctgaa
     2161 tttgctacgg atttaccctc tcttcaaagt gatcccagag tggatacagc aacagcagca
     2221 gcagcagcag cagcagcaac taaagctgag agtctctgca ctggtacagg tgacaagaca
     2281 ttgccatttc tgcacaatat taaaatcaaa gtagaagaca gtagtgctaa tgaagaatat
     2341 gaacctgagc ttattacaaa taagctaaag tgggagtgca atgatgccga gggtgagttt
     2401 tacaatatga ctgagaagaa ggaggaggac gccttggtac ccacagccaa ggaaggtttt
     2461 gcatgccctg agaaagaaac gccttcctta aatccactgg ctcagagtca gggcctctca
     2521 tgcactttag gatctccaaa acctgaggat ggggaatata aatttggtgc cagggtgaga
     2581 aaaaattacc ggacactagt actgggcaaa cgaccagtcc ttcagacacc tccagtcaaa
     2641 ccaaatttga aatcagctag aagccctcgt cctacaggta aaactgagac acatgaagga
     2701 acactggatg actttacagt tttaaacaga cgcaaaaagg tagccagcaa tgtagcatca
     2761 gcagtgaaaa ggccatttaa tttcatggca aattttcctt gtccaccttc actcattatt
     2821 gggaaggatg gggatttgtg gccagcgtat tccttaaaca ccactaagga ttcccaacct
     2881 cctcacaagg cccatcctat atggaaatgg cagctgggcg gttctgcaat acctcttcca
     2941 cctagtcaca aattcaggaa atttaattca taaaaaaatg ttttggaaga tattttctcg
     3001 aaccatatta ccttcctttt gttgtaaact gcacaggatg gcttgtacca agtccattaa
     3061 tggtgttaca ccccttttgg agtcctggtt tatcgcattt tgaagacaaa aatcggatta
     3121 cttttttttc ccattgcggg ttgttttttt ttttttttta tggtggggga ggggtgggag
     3181 aagggttggt ttacatacca cagactactt caggctaaag actcaagtaa cactcagtta
     3241 ttatggtaga gctggaacac tttactgttt caatggtaat aatgcaccgg tacctcaatt
     3301 caactgctac aaataaatgt caaaaggttg aataataaat atcacaatga gccattaagt
     3361 ttatgcacta gatttcagac ctgaaagtgt aactggtatt cagtgaaagt ttgttaggtt
     3421 acatggttac acaatgaggt agcaagaagt ttctgtgagc ccaaatgtaa ttttctggag
     3481 ctcttatttg tggggtgtct tttttatttt ttttctaaac ccagattccc tttccaatag
     3541 tagttgcact taactgtttt tttgttttgt tttgttttgt tttttaatgg aaagattggg
     3601 ggtctgagtc ctgattggat gctgatttaa aagctgccca ttgtgtgaga agtaaaaaaa
     3661 tacttttttt tttttaacct ttacagtcac tccttgcaac tggaaaagcc ccttctgcgc
     3721 tctcacccaa acatttaaaa taggatgact cttgctgtgc tcctgcttgt cttctgatct
     3781 gaagataact cttcaagctt tcaaaacaat taaaacattt ctcttaatag caggatgttt
     3841 aatggtctaa ctcatcctag tgtccaagca gtaaatacaa ccaagaaaaa gagtcataac
     3901 accccaagtg aaaaataact gatttcaggg ctttttggta ttagaactca ggcacttgga
     3961 ttttattacc ttatgctttt ttttttctgc atctctctaa acttctgttt caggccatcc
     4021 tgtgtataga acaggagagt ttctactgca agtgacaatc agaggtgact atctatattt
     4081 gcacttaaaa tcaaagtagt tccacaggca agtggtctag cccttggtga ggccatgctg
     4141 gtggactgtg ttgtaaagat gagagcagta aatcaaaatt atggaaattt gcactgttga
     4201 aaagcatgct ttagctttat tttcaattaa aaacactgtt taaaattcct ggttccatac
     4261 atttctactt attccagatt gaagaagggt taacaagaat gaatggcttt gttgacattt
     4321 tcacttgtaa tgtttttgcc tgaaagaaat gcatttattg ggtgcagtgt tttgtggtaa
     4381 tactttgtga tgagaccaat caggttctgg gcacaacact ggcaaacttc ctctcaaata
     4441 acagaaaaac ttttcaaact tgttataggc caactattaa aaagtttcat atctaagaaa
     4501 gtgaagcata aatcagttgt tattttaacg aaagttgtat ctagtaattt ttgggtcacc
     4561 aaattatgta tcttagatcc tggttatctt tagtctaaga agttgcatct acagaccata
     4621 aatcacaaag caaaacaaaa caccactaag atgtttactg tgtgaattta aagcattatt
     4681 tctcatggaa attcagctat ttattttcct taacctttta attcctaccc ccctttgaaa
     4741 ttttcccctt gactataaat gtttcagata gttctggatg gtctcagacc taattgctgt
     4801 gtattatctg tggttttcct cctgttgtaa aggacagagg ctgagaatac ctgcatccaa
     4861 atacatttgg atagagtgaa caga
//
