LOCUS       XM_036159695            5718 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus signal-regulatory protein alpha (Sirpa),
            transcript variant X8, mRNA.
ACCESSION   XM_036159695
VERSION     XM_036159695.1
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000068.8) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5718
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="2"
     gene            1..5718
                     /gene="Sirpa"
                     /gene_synonym="Bit; CD172a; Idd13.2; P84; Ptpns1; SHP-1;
                     SHPS-1; SIRP"
                     /note="signal-regulatory protein alpha; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 8 mRNAs, 24 ESTs, 1330 long SRA reads, 22 Proteins,
                     and 87% coverage of the annotated genomic feature by
                     RNAseq alignments, including 24 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:19261"
                     /db_xref="MGI:MGI:108563"
     CDS             2166..3674
                     /gene="Sirpa"
                     /gene_synonym="Bit; CD172a; Idd13.2; P84; Ptpns1; SHP-1;
                     SHPS-1; SIRP"
                     /codon_start=1
                     /product="tyrosine-protein phosphatase non-receptor type
                     substrate 1 isoform X2"
                     /protein_id="XP_036015588.1"
                     /db_xref="GeneID:19261"
                     /db_xref="MGI:MGI:108563"
                     /translation="MKAIKNPVHAKATTPQHLAEGATGKELKVTQPEKSVSVAAGDST
                     VLNCTLTSLLPVGPIRWYRGVGPSRLLIYSFAGEYVPRIRNVSDTTKRNNMDFSIRIS
                     NVTPADAGIYYCVKFQKGSSEPDTEIQSGGGTEVYVLAKPSPPEVSGPADRGIPDQKV
                     NFTCKSHGFSPRNITLKWFKDGQELHPLETTVNPSGKNVSYNISSTVRVVLNSMDVNS
                     KVICEVAHITLDRSPLRGIANLSNFIRVSPTVKVTQQSPTSMNQVNLTCRAERFYPED
                     LQLIWLENGNVSRNDTPKNLTKNTDGTYNYTSLFLVNSSAHREDVVFTCQVKHDQQPA
                     ITRNHTVLGFAHSSDQGSMQTFPDNNATHNWNVFIGVGVACALLVVLLMAALYLLRIK
                     QKKAKGSTSSTRLHEPEKNAREITQIQDTNDINDITYADLNLPKEKKPAPRAPEPNNH
                     TEYASIETGKVPRPEDTLTYADLDMVHLSRAQPAPKPEPSFSEYASVQVQRK"
ORIGIN      
        1 tttttttttt tttttgagac agggtttctc tgtatagccc tggctgtcct ggaactcact
       61 ttgtagacca ggctggcctc gaactcagaa atctgcctgc ctctgcctcc caagtactgg
      121 gcttaggcgt gtgccaccac acccagctaa ttttggagga gggttttcac aaggctttag
      181 tggacaccat ggtcctatca gacacaattt aaagagctgg agacactgca gctcagctca
      241 gatgctagaa ccaagttttc tttcttgccc aggcccccga actccgtatt ctcttccctt
      301 cagccacctc ttattccaac tatagtgacc ctttgagtgt aacaatcaag catggtaggc
      361 cctacttgaa tcttgcctac aggggttcct atttgcagaa ccaattctct tgggcttctg
      421 gaccaccctc ccgacgtgct agccacatac tgttgccctt acctaaccaa gctgacacac
      481 atgtgcactt gtaacctaca ctccctacaa gacctcctct gttcattctt gtcttcccct
      541 gcaccttctc ccagtctgca agtgagttct tgtaatcccc taggtccaaa gaaatacaac
      601 taatcttcct gctagggctg ccccatggtc ccttaaggat tgctgctgcc aaacacttct
      661 caaacactgt ccttgccctt ggtacatggt aggctcttct taaaatgcag tgcaaatatc
      721 agctcatgta actctcccag tggcagttct gggtcgctgc ttatgttggc ctggtctgct
      781 ttaaaaagag cagagacaca gaaacaaggt ctttctccaa gactgcagct tcttagacca
      841 ggaggaacga tctaaggctt ggaagctggg tcctgggttc aacagatgca cccttcctgc
      901 ctctcaaaaa caaacaaaca aacaaacaat aaaagaagaa aagaaagaaa aaaaactaaa
      961 aaatctccca ggcttttggt catgggtgca gaggactctg tggtgtgtgt gtgcgtgcgc
     1021 gcgcaccatt gcataagggg ctttctacat cattaggcaa tcatcctcca ctcctctgcc
     1081 cctaaacatc ctctttattg agaggatggg ccagtagggc ctgtcttgct tcattatgtc
     1141 cctcaaccac cattgtgaga agcaaaattt gctatctctg aacttccaac tcagaaactc
     1201 tccagttaat aagagagggt cttgattcct cttccctgcc ttggtgccca gccttctgcc
     1261 gattaaccaa gcacctgacc tagctcatgg aaatccagag ctagggtaca ttttgcatcc
     1321 agaggctctg tcctttggga taggctctcc tgtccctcct cttcctcatt agggtaacta
     1381 ttttgcagcc caggtctctc ctagtacagt gctgcctggg ccctctccac ctccaatcta
     1441 ttctccctga tagaaggcct ctggtctgtc tcctccctag ggcccagccc tgcccctctc
     1501 ctttccctgc cacagcattt ttgctgctcc tctcccccag cgcgtcttta ccaagaggca
     1561 ctgaagtcct tcctacacac acgctatttt tgtaccatca ctctctcctt cctctccccc
     1621 ttccccctgc atttacttcc tgcttttgct atacctcggg gccagctagg aaagatttgg
     1681 gcccctagga ctcacgccca cccggaggcc gaccttcggc tttgggacac acaagcaggg
     1741 cctctcgggg aggggcagaa agcaaacctc cccgccccct ccactctcca cccttgcaag
     1801 ctcccctgcc gcgggcagcc tcttgcccac tggagtctaa ggactggccg ggtgagaggc
     1861 cgagaccagg gggcgatcgg ccgccacttc cccagtccac cttaagagga ccaagtagcc
     1921 agcccgccgc gccgacctca gaaaaacaag tttgcgcaaa gtggtgcgcg gccagcctct
     1981 gggcagaggg agcggtgctt ccaccgcctg gcagccctgc gcgcggcggc gcagccgcgg
     2041 cccatggagc ccgccggccc ggcccctggc cgcctagggc cgctgctgct ctgcctgctg
     2101 ctctccgcgt cctgtttctg tacagaagta catcaagatg ggctcatgct acacatttca
     2161 cagaaatgaa ggccatcaaa aaccctgtcc atgctaaagc cacaactcca cagcatttgg
     2221 cagagggagc cacggggaag gaactgaagg tgactcagcc tgagaaatca gtgtctgttg
     2281 ctgctgggga ttcgaccgtt ctgaactgca ctttgacctc cttgttgccg gtgggaccca
     2341 ttaggtggta cagaggagta gggccaagcc ggctgttgat ctacagtttc gcaggagaat
     2401 acgttcctcg aattagaaat gtttcagata ctactaagag aaacaatatg gacttttcca
     2461 tccgtatcag taatgtcacc ccagcagatg ctggcatcta ctactgtgtg aagttccaga
     2521 aaggatcatc agagcctgac acagaaatac aatctggagg gggaacagag gtctatgtac
     2581 tcgccaaacc ttctccaccg gaggtatccg gcccagcaga caggggcata cctgaccaga
     2641 aagtgaactt cacctgcaag tctcatggct tctctccccg gaatatcacc ctgaagtggt
     2701 tcaaagatgg gcaagaactc caccccttgg agaccaccgt gaaccctagt ggaaagaatg
     2761 tctcctacaa catctccagc acagtcaggg tggtactaaa ctccatggat gttaattcta
     2821 aggtcatctg cgaggtagcc cacatcacct tggatagaag ccctcttcgt gggattgcta
     2881 acctgtctaa cttcatccga gtttcaccca ccgtgaaggt cacccaacag tccccgacgt
     2941 caatgaacca ggtgaacctc acctgccggg ctgagaggtt ctaccccgag gatctccagc
     3001 tgatctggct ggagaatgga aacgtatcac ggaatgacac gcccaagaat ctcacaaaga
     3061 acacggatgg gacctataat tacacaagct tgttcctggt gaactcatct gctcatagag
     3121 aggacgtggt gttcacgtgc caggtgaagc acgaccaaca gccagcgatc acccgaaacc
     3181 ataccgtgct gggatttgcc cactcgagtg atcaagggag catgcaaacc ttccctgata
     3241 ataatgctac ccacaactgg aatgtcttca tcggtgtggg cgtggcgtgt gctttgctcg
     3301 tagtcctgct gatggctgct ctctacctcc tccggatcaa acagaagaaa gccaaggggt
     3361 caacatcttc cacacggttg cacgagcccg agaagaacgc cagggaaata acccagatcc
     3421 aggacacaaa tgacatcaac gacatcacat acgcagacct gaatctgccc aaagagaaga
     3481 agcccgcacc ccgggcccct gagcctaaca accacacaga atatgcaagc attgagacag
     3541 gcaaagtgcc taggccagag gataccctca cctatgctga cctggacatg gtccacctca
     3601 gccgggcaca gccagccccc aagcctgagc catctttctc agagtatgct agtgtccagg
     3661 tccagaggaa gtgaatgggg ctgtggtctg tactaggccc catccccaca agttttcttg
     3721 tcctacatgg agtggccatg acgaggacat ccagccagcc aatcctgtcc ccagaaggcc
     3781 aggtggcacg ggtcctagga ccaggggtaa gggtggcctt tgtcttccct ccgtggctct
     3841 tcaacacctc ttgggcaccc acgtcccctt cttccggagg ctgggtgttg cagaaccaga
     3901 gggcgaactg gagaaagctg cctggaatcc aagaagtgtt gtgcctcggc ccatcactcg
     3961 tgggtctgga tcctggtctt ggcaacccca ggttgcgtcc ttgatgttcc agagcttggt
     4021 cttctgtgtg gagaagagct caccatctct acccaacttg agctttggga ccagactccc
     4081 tttagatcaa accgccccat ctgtggaaga actacaccag aagtcagcaa gttttcagcc
     4141 aacagtgctg gcctccccac ctcccaggct gactagccct ggggagaagg aaccctctcc
     4201 tcctagacca gcagagactc cctgggcatg ttcagtgtgg ccccacctcc cttccagtcc
     4261 cagcttgctt cctccagcta gcactaactc agcagcatcg ctctgtggac gcctgtaaat
     4321 tattgagaaa tgtgaactgt gcagtcttaa agctaaggtg ttagaaaatt tgatttatgc
     4381 tgtttagttg ttgttgggtt tcttttcttt ttaatttctt tttctttttt gatttttttt
     4441 ctttccctta aaacaacagc agcagcatct tggctctttg tcatgtgttg aatggttggg
     4501 tcttgtgaag tctgaggtct aacagtttat tgtcctggaa ggattttctt acagcagaaa
     4561 cagatttttt tcaaattccc agaatcctga ggaccaagaa ggatccctca gctgctactt
     4621 ccagcaccca gcgtcactgg gacgaaccag gccctgttct tacaaggcca catggctggc
     4681 cctttgcctc catggctact gtggtaagtg cagccttgtc tgacccaatg ctgacctaat
     4741 gttggccatt ccacattgag gggacaaggt cagtgatgcc ccccttcact cacaagcact
     4801 tcagaggcat gcagagagaa gggacactcg gccagctctc tgaggtaatc agtgcaagga
     4861 ggagtccgtt ttttgccagc aaacctcagc aggatcacac tggaacagaa cctggtcata
     4921 cctgtgacaa cacagctgtg agccagggca aaccacccac tgtcactggc tcgagagtct
     4981 gggcagaggc tctgaccctc caccctttaa actggatgcc ggggcctggc tgggcccaat
     5041 gccaagtggt tatggcaacc ctgactatct ggtcttaaca tgtagctcag gaagtggagg
     5101 cgctaatgtc cccaatccct ggggattcct gattccagct attcatgtaa gcagagccaa
     5161 cctgcctatt tctgtaggtg cgactgggat gttaggagca cagcaaggac ccagctctgt
     5221 agggctggtg acctgatact tctcataatg gcatctagaa gttaggctga gttggcctca
     5281 ctggcccagc aaaccagaac ttgtctttgt ccgggccatg ttcttgggct gtcttctaat
     5341 tccaaagggt tggttggtaa agctccaccc ccttctcctc tgcctaaaga catcacatgt
     5401 gtatacacac acgggtgtat agatgagtta aaagaatgtc ctcgctggca tcctaatttt
     5461 gtcttaagtt tttttggagg gagaaaggaa caaggcaagg gaagatgtgt agctttggct
     5521 ttaaccaggc agcctggggg ctcccaagcc tatggaaccc tggtacaaag aagagaacag
     5581 aagcgccctg tgaggagtgg gatttgtttt tctgtagacc agatgagaag gaaacaggcc
     5641 ctgttttgta catagttgca acttaaaatt tttggcttgc aaaatatttt tgtaataaag
     5701 atttctgggt aacaataa
//
