LOCUS       NM_176987               4805 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus SUMO-interacting motifs containing 1 (Simc1), mRNA.
ACCESSION   NM_176987
VERSION     NM_176987.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4805)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC165145.2 and AC155262.2.
            
            On Jan 27, 2022 this sequence version replaced NM_176987.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-212               AC165145.2         140282-140493
            213-2915            AC165145.2         160459-163161
            2916-3148           AC165145.2         164793-165025
            3149-3218           AC165145.2         165643-165712
            3219-3373           AC165145.2         173571-173725
            3374-3526           AC165145.2         176193-176345
            3527-3655           AC165145.2         177913-178041
            3656-3812           AC155262.2         76596-76752
            3813-3897           AC155262.2         76874-76958
            3898-4805           AC155262.2         80002-80909
FEATURES             Location/Qualifiers
     source          1..4805
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 28.74 cM"
     gene            1..4805
                     /gene="Simc1"
                     /gene_synonym="4732471D19Rik"
                     /note="SUMO-interacting motifs containing 1"
                     /db_xref="GeneID:319719"
                     /db_xref="MGI:MGI:2442599"
     exon            1..212
                     /gene="Simc1"
                     /gene_synonym="4732471D19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             84..4148
                     /gene="Simc1"
                     /gene_synonym="4732471D19Rik"
                     /note="platform element for inhibition of autolytic
                     degradation"
                     /codon_start=1
                     /product="SUMO-interacting motif-containing protein 1"
                     /protein_id="NP_795961.3"
                     /db_xref="CCDS:CCDS26528.2"
                     /db_xref="GeneID:319719"
                     /db_xref="MGI:MGI:2442599"
                     /translation="MEDFIVISDDSGSESSAGTRSGRARRLRRALSRTPGALPRRTVD
                     FIDLTRENRARTKDRNGLCVIDLTRNEEENRPIATLDLTLEPVASSQKEPTSLQTCTS
                     LSGKEVMEAHEDRGSQPAAQRIINNDPVDLDLLEENLFEGSRPPTSISQDSVYPPEPN
                     CSSITYKGDLSFLTSLQLSSDVSSFSSTSNQRASLPCPQQDVPCQSQGLLCPLQALSC
                     PQTASPCPPRASSCPPQALSCPPQALSCPSQTLQCQLQALPQPPQEVPCSTQNVPCPQ
                     QNMPSTPQGLSWHPRHTLYPYQDTLGLPQDVPGRPQNMSYPQDVTQLQDMPWSLHDMP
                     LSLQDVLQSLQDVPPLLGDVPPSPEVMQLPGYVTQTSRDVIQSPAGVTQSLGSMMQSP
                     GSVTQSLRSVMQSSGSVTQSLRSVMQSSGSVTQSLRSVMQSSGSVMQSPGGVTQSLRS
                     VTQSPGGVMQSPGGVMQSPRDVMQSPRDVMQSPRDVMQSPRGVTQSLGSMMQSPGGVM
                     QSLRSVMQSSGGVTQSLRSVMQSPGGVMQSPGGVTQSPRGMIKSPGMMLSPGDVIQSL
                     NSVPQSSRDRMQSAGHVPSASGDAIQSPGGMSPTSRDRMQSPGGVSLATEDSIQLPGG
                     VPLSSDVIQSQGGVPLSSKDRMQSPGGVPPSSGDMIQSQGGVPQSLGDAIQSAGGVPQ
                     SSGDAIQSPGGVSLATGDSIQLPGGVPLSSGDVIQSQGGVPRSSRDRMQSPGGVPPSS
                     GGVIQSPGGVSPASGDAIQSPGSVLPASGDAIQSAGGVLLASGDAIQSPRSVPQSPSG
                     TLRSPGNMSESLGDTPNLSGDVSNSPQALLDLARDRPKSSPNDVQNRDTPMDISASSS
                     SSCSANPQSRQSEFKLDKVPWLTITDSSARREKSLPQLANPGSAQIQGQIPQVGVYNR
                     PCLHRLKYFLRPPVHHLFFQTLIPDKDTRESKGQKLEPIPHRRLRMVTNTIEENFPLG
                     TVQFLMDFVSPQHYPPREIVAHIVQKILLSGSETVDVLKEAYMLLMKIQQLHPANAKT
                     VEWDWKLLTYVMEEEGQTLPGRVLFLRYVVQTLEDDFQQILRRQRQHLQQSIANTVLS
                     CDKQPHNVRDVIKWLVKAVTENELTPPQDETQTSPRTGVLKTSSDHLSPRPNQNKNTN
                     QLIVCQLQRMLSIAVEVDRTPTCSSNKIAEMMFGFVLDIPERSQREMFFTTMESHLLR
                     CKVLEIIFLHSCETPTRLPLSLAQTLYFLNNSTSLLKCQSDKTQWQTWDELVEHLQFL
                     LSSYQHVLREHLRSSVIDRKDLIIKRIKPKPQQGDDITVLDVEKQIEAFRSRLVHILG
                     EPLVPQLQDKVHLLKLLLFYAADLNPDTEPASEH"
     exon            213..2915
                     /gene="Simc1"
                     /gene_synonym="4732471D19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2916..3148
                     /gene="Simc1"
                     /gene_synonym="4732471D19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3149..3218
                     /gene="Simc1"
                     /gene_synonym="4732471D19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3219..3373
                     /gene="Simc1"
                     /gene_synonym="4732471D19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3374..3526
                     /gene="Simc1"
                     /gene_synonym="4732471D19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3527..3655
                     /gene="Simc1"
                     /gene_synonym="4732471D19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3656..3812
                     /gene="Simc1"
                     /gene_synonym="4732471D19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3813..3897
                     /gene="Simc1"
                     /gene_synonym="4732471D19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3898..4805
                     /gene="Simc1"
                     /gene_synonym="4732471D19Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4376..4381
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Simc1"
                     /gene_synonym="4732471D19Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      4403
                     /gene="Simc1"
                     /gene_synonym="4732471D19Rik"
                     /note="major polyA site"
     regulatory      4784..4789
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Simc1"
                     /gene_synonym="4732471D19Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4805
                     /gene="Simc1"
                     /gene_synonym="4732471D19Rik"
ORIGIN      
        1 gcagtcgctt cagcagctgg aaccggagtc ggagtcgccg gggccgctcg ccgctcgcgc
       61 gtggctccgc cgggcccgta gccatggagg actttatcgt gatctccgac gacagtggct
      121 ccgagagctc ggccgggacc cgctcgggca gggcgcggag gctgcgccgg gccctgtctc
      181 ggacccccgg cgcgctgccc cgccgaaccg tggacttcat tgacttaact agagaaaacc
      241 gagcaaggac aaaagaccgg aatggactct gtgtgattga tctaacaaga aatgaggaag
      301 aaaataggcc tattgccact cttgatttga ctttagaacc tgtagcttcc tctcagaagg
      361 agccaaccag tcttcagaca tgtaccagtc tctcgggcaa agaagtgatg gaagcccatg
      421 aagatagagg ctctcagcct gcagcacaga gaatcattaa caatgatcct gtagatttgg
      481 atttgctaga ggaaaacctg tttgaaggtt ctcgaccccc tacatctatc agccaggact
      541 ctgtttatcc accagaacca aactgtagct caatcacata taaaggtgac ctcagcttct
      601 tgacaagcct acagctctct tcagatgtta gctccttctc ctccacaagc aatcagaggg
      661 cctctttgcc atgcccacag caagatgtgc cttgtcaatc acaaggcttg ctatgcccgc
      721 tacaggcctt atcatgccca caaacagctt caccatgtcc accacgagct tcctcatgcc
      781 caccacaagc cctgtcatgc ccacctcaag ctttgtcatg cccatcacaa actttacagt
      841 gccaactcca agctttgcct caaccacctc aagaagtgcc atgctctacc caaaatgtac
      901 cgtgccctca gcagaatatg ccaagcacac ctcaaggctt atcatggcat cctcgacaca
      961 ccctataccc atatcaagac actctgggcc tacctcaaga tgttccaggc cgacctcaaa
     1021 acatgtcata tccacaagat gtgacacaac tgcaagacat gccatggtca ctacatgaca
     1081 tgccactgtc actacaagat gtgttacagt cactgcaaga tgtgccacca ttgctgggag
     1141 atgtgccgcc atcaccagaa gtgatgcagt taccaggata tgtgacacag acatcaagag
     1201 atgtgattca gtcaccggca ggtgtgacac agtcactagg aagtatgatg cagtcaccag
     1261 gaagtgtgac ccagtcacta agaagtgtga tgcagtcatc aggaagtgtg acccagtcac
     1321 taagaagtgt gatgcagtca tcaggaagtg tgacccagtc actaagaagt gtgatgcagt
     1381 catcaggaag tgtgatgcag tcaccaggag gtgtgacaca gtcactaaga agtgtgacgc
     1441 agtcaccagg aggtgtgatg cagtcaccag gaggtgtaat gcagtcacca agagatgtga
     1501 tgcagtcacc aagagatgtg atgcagtcac caagagatgt gatgcagtca ccaagaggtg
     1561 tgacacagtc actaggaagt atgatgcagt caccaggagg tgtgatgcag tcactaagaa
     1621 gtgtaatgca gtcatcagga ggtgtgacac agtcactaag aagtgtgatg cagtcaccag
     1681 gaggtgtgat gcagtcacca ggaggtgtga cacagtcacc aagaggtatg attaagtcac
     1741 caggaatgat gctgtcacca ggagatgtga tacagtcact aaacagtgtg ccacagtcat
     1801 caagagatag gatgcagtca gcaggacatg tgccatcagc atcaggagat gcaatacaat
     1861 caccaggagg tatgtcaccg acatcaagag ataggatgca gtcaccagga ggtgtgtcac
     1921 tggcaacaga agattcgata cagttaccag gaggtgtgcc actatcatca gatgtgatac
     1981 agtcacaagg aggtgtgcca ttatcatcaa aagataggat gcagtcacca ggaggtgtgc
     2041 caccatcatc tggagatatg atacagtcac aaggaggtgt gccacaatca ttaggagatg
     2101 caatacagtc agcaggaggt gtgccacaat catcaggaga tgcgatacag tcaccaggag
     2161 gtgtgtcact ggcaacagga gattcgatac agttaccagg aggcgtgcca ctatcatcgg
     2221 gagatgtgat acagtcccaa ggaggtgtgc cacggtcatc aagggatagg atgcagtcac
     2281 caggaggtgt gccaccatca tctggaggtg tgatacagtc accaggaggt gtgtcaccag
     2341 catcaggaga tgcaatacag tcaccaggaa gtgtgttacc ggcatcagga gatgcaatac
     2401 agtcagcagg aggtgtgtta ctggcatcag gagatgcaat acagtcacca agaagtgtgc
     2461 cacagtcacc tagcggtaca ttgcggtcac caggcaatat gtcagagtca cttggagata
     2521 caccaaactt atcaggagat gtgtcaaact caccacaagc attattggac ttagcaagag
     2581 acaggccgaa gtcttccccg aatgatgtgc agaatcgtga tactcctatg gatatctcag
     2641 cttcatcctc ttcaagttgc tctgctaacc cacaatctcg acagtctgaa tttaaattag
     2701 ataaagttcc ttggctcact atcacagata gctcagccag gagagagaaa tcactgccac
     2761 agcttgccaa ccctgggtct gctcagatac aaggacaaat accacaagtt ggggtataca
     2821 atagaccttg cctgcataga ctgaaatact tcttacggcc tccagtacat catctcttct
     2881 tccagacatt aataccagat aaagatacac gagagagcaa gggtcagaaa ttagaaccca
     2941 tccctcatcg aagactaaga atggtgacaa acactattga agaaaacttc cctttgggga
     3001 ctgtgcagtt tttaatggac tttgtttcac cccaacatta cccacccaga gaaattgtgg
     3061 ctcacatcgt ccagaaaatc ctgctcagtg gctctgagac tgtggatgtc ctcaaggagg
     3121 cctacatgct tctcatgaaa atccaacagc tgcatccagc caatgccaag acagtggagt
     3181 gggactggaa actgctcacc tatgtcatgg aggaagaggg acaaactctg cctggacgag
     3241 ttctctttct acgctacgta gtgcaaaccc tggaagatga cttccagcag atcttgagga
     3301 gacagcggca gcacctacag caatccattg caaacactgt tctgtcatgt gacaaacagc
     3361 ctcacaatgt cagagatgtt attaagtggc tggtcaaagc agtgactgaa aatgaattaa
     3421 ctccacccca agatgagact cagacctctc caagaacagg agtcttgaaa actagcagtg
     3481 accatctgtc tccccggcct aaccagaaca agaacaccaa tcaactgatt gtgtgtcagc
     3541 ttcagaggat gttgtccatc gctgtagagg tggacaggac tccaacctgc agctccaata
     3601 aaatagcgga gatgatgttt gggtttgtgc tggatatccc tgagaggagc cagagggaga
     3661 tgttctttac taccatggaa agccaccttc tgcgatgcaa agtcctggag atcatattcc
     3721 tgcacagctg tgagacaccc acccgtctcc ccttgtctct ggcccagacc ctctattttc
     3781 tgaacaactc cacgtccctg ctcaagtgtc aatcagataa aacgcagtgg cagacatggg
     3841 atgagctggt tgaacatctg cagttcctgc tgtccagtta tcaacacgtg ctgagagagc
     3901 acctacggag ctcagtgatt gatcggaaag acttaatcat caaaagaatt aagcccaagc
     3961 cccaacaagg agatgacatc acggtgctgg atgtggagaa gcagatcgag gccttccgca
     4021 gccgcctggt ccacatattg ggagaacctt tagtccccca gctccaagac aaagtgcatt
     4081 tgttgaagct gctgctcttc tatgctgcgg acttgaaccc cgacacagag cctgcttcag
     4141 agcactgagg cagccagact tctaagcact gcgcaccaag aatacctcct gactaccgcc
     4201 agctacttag aagccctgaa gtatgaacag tagttaggaa catcatagga ccaaacctat
     4261 cttatttatc agtaggttgt aataactttg taactcttca gtatatattt tttttataat
     4321 ctttatccta gcctattcaa atttggctta aatatacaag gtgtatatat tttttattaa
     4381 attatttatc tatgcttttg aaacaggcag tgatatgcac tatatgtcca acatttccat
     4441 gcaagatgtg aaagaaccct tctgcacaat ccatcagtgt tacactggtc aagatactga
     4501 cggcccgctc ggcccagctc tgaaaaaaac attagttttt cctgaataga ccatgttcta
     4561 tactagactt tttatattgc ccataaatat gactctgtgg ccagtttatt aagtctaaca
     4621 aagcaggcaa agaaacaaga gcctgtcaaa cctgtggtgt taataagata gaataagatg
     4681 tttacagtgc ttgggctcca ctatggggca ggcagaatgg acaagacaga cctgggcttg
     4741 agaaagtagt aaagattttt atttgtcaat acaagataac acaaataaat taatttttac
     4801 aacaa
//
