LOCUS       NP_853621                569 aa            linear   ROD 04-MAR-2025
DEFINITION  protein SHQ1 homolog [Mus musculus].
ACCESSION   NP_853621
VERSION     NP_853621.2
DBSOURCE    REFSEQ: accession NM_181590.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 569)
  AUTHORS   Chang,C.H., Wong,L.C., Huang,C.W., Li,Y.R., Yang,C.W., Tsai,J.W.
            and Lee,W.T.
  TITLE     Pathogenic SHQ1 variants result in disruptions to neuronal
            development and the dopaminergic pathway
  JOURNAL   Exp Neurol 382, 114968 (2024)
   PUBMED   39326821
REFERENCE   2  (residues 1 to 569)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 569)
  AUTHORS   Hieronymus,H., Iaquinta,P.J., Wongvipat,J., Gopalan,A., Murali,R.,
            Mao,N., Carver,B.S. and Sawyers,C.L.
  TITLE     Deletion of 3p13-14 locus spanning FOXP1 to SHQ1 cooperates with
            PTEN loss in prostate oncogenesis
  JOURNAL   Nat Commun 8 (1), 1081 (2017)
   PUBMED   29057879
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY776788.1, AK012978.1, CF746515.1, AC162389.6 and CB522035.1.
            
            On Feb 6, 2008 this sequence version replaced NP_853621.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK012978.1, SRR9219380.43009.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 46.82 cM"
     Protein         1..569
                     /product="protein SHQ1 homolog"
                     /calculated_mol_wt=63327
     Region          236..421
                     /region_name="SHQ1"
                     /note="SHQ1 protein; pfam04925"
                     /db_xref="CDD:461483"
     Region          439..482
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q7TMX5.2)"
     Region          545..569
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q7TMX5.2)"
     CDS             1..569
                     /gene="Shq1"
                     /gene_synonym="2810403P18Rik; Grim-1"
                     /coded_by="NM_181590.5:97..1806"
                     /db_xref="CCDS:CCDS39580.2"
                     /db_xref="GeneID:72171"
                     /db_xref="MGI:MGI:1919421"
ORIGIN      
        1 mltpafeltq dcdfltvair vpharasefd vyfegvdfkf yakpyflrlt lpgrivengs
       61 eqgtydadkg iftirlpket pgqhfeglnm ltallaprks rsakplveei gasgvaeega
      121 ddedeefdwe ieqtpyeevs estlqsqchy gfgnlragvv qrlqdelsev idikdpdftp
      181 vterrqkrla aelakfdpdh yladffedea veqilkyspw wndahaemva slgknqeqgd
      241 saalvsfsee ekyqlrkfvn ksylldktah rqvyyglvdi llaycyevrv tegehsvesa
      301 wtirklsptl cwfetwtdvh eilvsfgrrv lcyplyrhfk lvlkayrdti kilqlgksav
      361 lkclldvhkv fqendpayil ndlyisdycv wiqkakskkl aaltealkav slskaqlgle
      421 lpeleaaall vqeeegagra aqcnpshqap hsspepsdsd stsssgteds aseqeepagt
      481 qpslltslqa plleedsali iresglcrnm asqgcevsqg qplasarapl ieelgdalkm
      541 lrvstphgvs agshgsveda eergqvpcd
//
